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    METHOD OF EXTRACTING MATERIAL FROM A FLUID AND EXTRACTOR
    41.
    发明申请
    METHOD OF EXTRACTING MATERIAL FROM A FLUID AND EXTRACTOR 审中-公开

    公开(公告)号：US20200038877A1

    公开(公告)日：2020-02-06

    申请号：US16341436

    申请日：2017-10-13

    Applicant: Randox Laboratories Ltd.

    Inventor： Stuart Jackson ,  Stephen Peter Fitzgerald ,  Ivan McConnell ,  John Lamont

    IPC: B03C1/01 ,  B03C1/28 ,  B01F13/08 ,  C12N15/10

    Abstract: There is provided a method of extracting material from a fluid method of extracting material from a fluid, the fluid being held within a fluid chamber. The method comprises drawing, with a magnetic field generating system, at least one magnetically susceptible member through the fluid around a closed path between at least three points in the chamber, said at least one member being adapted to bind to material in fluid in the chamber. The at least three points are arranged relative to each other in a shape having at least two dimensions, the magnetic field generating system being configured to move the at least on magnetically susceptible member directly between the at least three points, material in the fluid binding to the at least one magnetically susceptible member when it comes into contact with the at least one member as it moves through the fluid.

    MEASUREMENT OF FABP FOR DIAGNOSIS
    43.
    发明申请
    MEASUREMENT OF FABP FOR DIAGNOSIS 审中-公开

    公开(公告)号：US20190154672A1

    公开(公告)日：2019-05-23

    申请号：US16313316

    申请日：2017-06-30

    Applicant: Randox Laboratories Ltd. ,  Randox Teoranta

    Inventor： Ivan McConnell ,  Peter Fitzgerald ,  John Lamont ,  Ciaran Richardson

    IPC: G01N33/543 ,  G01N33/92 ,  C07K16/18

    Abstract: The present invention relates to a multiplexing system comprising a support substrate having immobilised thereto one or more of the following proteins, fragments thereof or a binding molecule, wherein the binding molecule binds specifically to one of the following proteins: E-FABP, B-FABP, IL-FABP, I-FABP, M-FABP, A-FABP, H-FABP, L-FABP or T-FABP. Another aspect is directed to a method for characterising the pattern of FABP antigens existing within a biological sample to reveal information useful in the diagnosis or disease or injury.

    Identification of genetic variants
    45.
    发明授权
    Identification of genetic variants 有权
    鉴定遗传变异

    公开(公告)号：US09447469B2

    公开(公告)日：2016-09-20

    申请号：US14323775

    申请日：2014-07-03

    Applicant: RANDOX LABORATORIES LTD.

    Inventor： John V. Lamont

    IPC: C12Q1/68 ,  C12P19/34 ,  A61K31/404 ,  A61K31/4439 ,  A61K31/517

    CPC classification number: C12Q1/6883 ,  A61K31/404 ,  A61K31/4439 ,  A61K31/517 ,  C12Q2600/106 ,  C12Q2600/156

    Abstract: The present disclosure provides a method for identifying whether a subject is more or less likely to be responsive to VEGF-based therapy, comprising screening a nucleic acid sample obtained from the subject to provide output information which identifies the presence or absence of an allelic variant, wherein the presence or absence of an allelic variant indicates whether the subject is more or less likely to be responsive to VEGF-based therapy.

    Abstract translation: 本公开提供了用于鉴定受试者是或多或少可能对基于VEGF的治疗有反应的方法，其包括筛选从受试者获得的核酸样品以提供识别等位变体的存在或不存在的输出信息， 其中等位基因变体的存在或不存在表明受试者是或多或少可能对基于VEGF的治疗有反应。

    Spin trap for use in biological systems
    48.
    发明申请
    Spin trap for use in biological systems 审中-公开
    用于生物系统的旋转阱

    公开(公告)号：US20030109051A1

    公开(公告)日：2003-06-12

    申请号：US10269884

    申请日：2002-10-15

    Applicant: RANDOX LABORATORIES LTD

    Inventor： Stephen Peter Fitzgerald ,  Lynne Hamilton ,  Paul Graham Winyard

    IPC: G01N033/50

    CPC classification number: G01N33/84

    Abstract: A spin-trapping assay for nitric oxide, in a biological system such as whole blood, uses as the spin trap a lipid-soluble nitrobenzene compound such as 2,6-dimethylnitrosobenzene.

    Abstract translation: 在诸如全血的生物系统中，一氧化氮的自旋捕获测定法用作可溶性硝基苯化合物如2,6-二甲基亚硝基苯的自旋阱。

    Assay cartridge and support housing
    50.
    发明授权
    Assay cartridge and support housing 有权

    公开(公告)号：US12246323B2

    公开(公告)日：2025-03-11

    申请号：US17602826

    申请日：2020-04-09

    Applicant: RANDOX LABORATORIES LTD

    Inventor： Marc Wharry ,  Martin Reid ,  Peter Fitzgerald

    IPC: B01L3/00 ,  B01L9/00

    Abstract: An assay cartridge for use in a molecular diagnostics assay having an assay region; a first end comprising a first engagement member for engaging with a support housing; and a second end comprising a second engagement member for engaging with a support housing. The second engagement member has a clip, the clip being formed by a resilient element extending from the second end of the cartridge and a fastening element extending from said resilient element. The clip has a release element extending from the resilient element actuatable to release the clip from a caddy in use.

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