公开(公告)号：US12025561B2

公开(公告)日：2024-07-02

申请号：US17604006

申请日：2020-04-15

Applicant: Ohio State Innovation Foundation

Inventor： Heather Allen ,  Juan Velez

IPC: G01N21/65 ,  G01J3/18 ,  G01J3/28 ,  G01J3/44

CPC classification number: G01N21/65 ,  G01J3/18 ,  G01J3/2823 ,  G01J3/4412 ,  G01N2201/06113 ,  G01N2201/1296

Abstract: A hand-held sized imaging instrument identifies molecules with high selectivity and in complex mixtures. The instrument uses inelastic scattering and scattering intensities from with machine learning algorithms based on convolutional neural networks (CNN's) to identify the presence of a specified chemical or combination of chemicals. A laser is housed within the instrument to initiate a material response of a sample using laser light of a specified wavelength. The instrument uses an image sensor to capture visible images with inelastic scattering information. The CNN is able to classify the image to determine whether the specified chemical or combination of chemicals is present in the sample. The instrument is inexpensive, portable, easy to use by anyone (nonchemist, nonprofessional), and safe (laser is completely housed). The instrument can be used efficiently and easily for quality control, security, and other applications to reliably detect the presence of specified substances.

公开(公告)号：US11976971B2

公开(公告)日：2024-05-07

申请号：US17272667

申请日：2019-09-04

Applicant: Michigan Aerospace Corporation

Inventor： Will Johnson

IPC: G01J3/02 ,  F21V8/00 ,  G01J3/18 ,  G01J3/28 ,  G01S17/95

CPC classification number: G01J3/0221 ,  G01J3/18 ,  G01J3/2803 ,  G01S17/95 ,  G02B6/0008 ,  G01J2003/2813

Abstract: Spectrographic measurements are often limited by the amount of light that is available. Photons that are not collected or measured reduce the signal to noise and therefore reduce measurement precision. This invention collects the zero order light and sends it through the spectrometer again. In an atmospheric LIDAR, the zero order recycling is estimated to increase the rotational Raman signal by an additional 20%. A grating based spectrometer where the zero order light is collected by a lens or mirror and focused into a fiber optic that sends the light to the input slit where it is directed into the spectrometer again. There can be a plurality of recycle fibers. The detector can be either a single linear array or a two dimensional array such as a CCD or CMOS camera.

公开(公告)号：US20240133739A1

公开(公告)日：2024-04-25

申请号：US18319615

申请日：2023-05-17

Applicant: Wayne State University

Inventor： Gregory William Auner ,  Michelle Ann Brusatori ,  Changhe Huang

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G01N21/03

CPC classification number: G01J3/44 ,  G01J3/0208 ,  G01J3/1838 ,  G01J3/2803 ,  G01N21/03 ,  G01J2003/1861

Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.

公开(公告)号：US20240102859A1

公开(公告)日：2024-03-28

申请号：US18010430

申请日：2022-09-07

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ki Hun Jeong ,  Jung Woo Park ,  Jae Hun Jeon ,  Gi Beom Kim

IPC: G01J3/02 ,  G01J3/04 ,  G01J3/18 ,  G01J3/28

CPC classification number: G01J3/0259 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/04 ,  G01J3/18 ,  G01J3/2803

Abstract: The disclosure relates to an ultrathin micro-spectrometer and a method of manufacturing the same, and more particularly, relates to an ultrathin micro-spectrometer including: a lens portion including: a convex lens; and a back-reflection grating layer which is formed on a rear surface of the convex lens and on the same surface of which a reflective diffraction grating and a first planar reflector are arranged; a substrate layer which is disposed to be spaced apart from the lens portion and on which a light incidence microslit is formed; a second planar reflector which is formed on the substrate layer; and a complementary metal-oxide-semiconductor (CMOS) sensor on which light reflected by the lens portion is focused, and a method of manufacturing the same.

公开(公告)号：US11933735B2

公开(公告)日：2024-03-19

申请号：US17440896

申请日：2020-03-25

Applicant: OSAKA UNIVERSITY

Inventor： Tsuyoshi Konishi

IPC: G01N21/88 ,  G01J3/18 ,  G01J3/42 ,  G01N21/31

CPC classification number: G01N21/8806 ,  G01J3/18 ,  G01J3/42 ,  G01N21/31 ,  G01N2021/8845 ,  G01N2021/8854

Abstract: An optical detection device is an optical detection device that detects a desired wavelength component included in input light, and includes: a spectrometer including, for instance, a diffraction grating that receives the input light as an input and outputs an alignment of spectra each of which is a duplication of a spectrum of the input light; a second slit array including an array of three or more slits that pass light beams of wavelengths at three or more locations in the alignment of the spectra that are output from the spectrometer; and an imaging element composed of an array of pixels that receive the light beams, having passed through the second slit array, each of the light beams having three or more wavelength components. At least two pitches between slits are different in the array of the three or more slits included in the second slit array.

公开(公告)号：US20240068870A1

公开(公告)日：2024-02-29

申请号：US18272256

申请日：2022-01-11

Applicant: Konica Minolta, Inc.

Inventor： Takashi KAWASAKI

IPC: G01J3/28 ,  G01J3/18

CPC classification number: G01J3/2823 ,  G01J3/18

Abstract: A wavelength of incident light is measured based on signals from a plurality of pixels of a photoelectric conversion element that are arranged in a dispersion direction in which the incident light is dispersed by a spectroscopic section. In correction of a shift in wavelength, a measured amount of shift in wavelength that is a difference between a measured value obtained when an emission line wavelength of incident light from a light source for wavelength shift correction that emits light including an emission line at least one wavelength in a range of wavelengths into which light can be dispersed by the spectroscopic section is measured and an original emission line wavelength is calculated. A reference amount of shift in emission line wavelength is calculated by a polynomial in which a characteristic of a wavelength shift that occurs is represented by a linear or higher polynomial with a variable indicating the wavelength or a parameter relating to the wavelength. Each coefficient of the polynomial is determined based on the calculated measured amount of shift in emission line wavelength and the reference amount of shift in emission line wavelength, and the wavelength of the incident light is corrected based on the determined polynomial.

公开(公告)号：US20240044710A1

公开(公告)日：2024-02-08

申请号：US18482411

申请日：2023-10-06

Applicant: GIGAPHOTON INC.

Inventor： Natsuhiko KOUNO ,  Masato MORIYA

IPC: G01J3/45 ,  G01J3/18

CPC classification number: G01J3/45 ,  G01J3/18

Abstract: A deterioration evaluation method of a line sensor includes detecting an interference fringe of pulse laser light using the line sensor; calculating, based on a signal value obtained from each of a plurality of sensor channels included in a sensor channel range being at least a part of the line sensor in accordance with light intensity of the interference fringe, an evaluation value which is an index of deterioration for each of the sensor channels or each group of the sensor channels, and storing the evaluation value in a storage device; and determining a deterioration state of the line sensor based on the evaluation value.

公开(公告)号：US11874168B2

公开(公告)日：2024-01-16

申请号：US17723815

申请日：2022-04-19

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Sung Hyun Nam ,  Woo Chang Lee

IPC: G01J3/02 ,  G01J3/18

CPC classification number: G01J3/0275 ,  G01J3/0202 ,  G01J3/0229 ,  G01J3/18

Abstract: A spectrometer includes: a dispersive element configured to split light; a detector comprising a plurality of pixels configured to receive the split light; an optical mask disposed in an optical path of the light between the dispersive element and the detector and comprising a plurality of light transmitting portions and a plurality of light blocking portions which are arranged alternately; and a driver configured to control a position of the optical mask or a position of the detector, and change a light incident area of each of the plurality of pixels to receive the light incident on the plurality of light transmitting portions of the optical mask.

公开(公告)号：US11867631B2

公开(公告)日：2024-01-09

申请号：US17527828

申请日：2021-11-16

Applicant: OndaVia, Inc.

Inventor： Mark C. Peterman ,  Merwan Benhabib ,  Samuel Kleinman

IPC: G01N21/65 ,  G01N21/47 ,  G01N21/63 ,  G01N21/66 ,  G01N33/18 ,  G01J3/02 ,  G01J3/18 ,  G01J3/44 ,  B01L3/00 ,  G01N27/447 ,  G01N30/60 ,  G01N21/49 ,  G01N21/68 ,  G01N21/27 ,  G01N30/00 ,  G01J3/28

CPC classification number: G01N21/65 ,  B01L3/502715 ,  B01L3/502761 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/18 ,  G01J3/44 ,  G01J3/4412 ,  G01N21/276 ,  G01N21/47 ,  G01N21/4785 ,  G01N21/49 ,  G01N21/63 ,  G01N21/658 ,  G01N21/66 ,  G01N21/68 ,  G01N27/44704 ,  G01N27/44791 ,  G01N30/6095 ,  G01N33/18 ,  B01L2200/04 ,  B01L2200/0652 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/0867 ,  B01L2400/0418 ,  B01L2400/0421 ,  G01J2003/2866 ,  G01J2003/2879 ,  G01N30/6065 ,  G01N2021/651 ,  G01N2021/656 ,  G01N2030/0095 ,  G01N2201/0221 ,  G01N2201/13

Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.

公开(公告)号：US11860122B2

公开(公告)日：2024-01-02

申请号：US18098060

申请日：2023-01-17

Applicant: Life Technologies Corporation

Inventor： Shaohong Wang

IPC: G01J3/44 ,  G01N27/447 ,  G01J3/02 ,  G01J3/18

CPC classification number: G01N27/44721 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0289 ,  G01J3/0294 ,  G01J3/18 ,  G01J3/4406 ,  G01N27/44791

Abstract: A system for separating biological molecules includes a plurality of capillaries, a capillary mount, a plurality of optical fibers, a fiber mount, an optical detector, and a motion stage. The plurality of capillaries are configured to separate biological molecules in a sample. Each capillary comprising a detection portion configured to pass electromagnetic radiation into the capillary. The plurality of capillaries are coupled to the capillary mount such that the detection portions are fixedly located relative to one another. Each optical fiber includes a receiving end to receive emissions. The optical fibers are coupled to the fiber mount such that the receiving ends of the optical fibers are fixedly located relative to one another. The optical detector is configured to produce an alignment signal. The motion stage is configured to align the receiving ends of the optical fibers to the detection portions based on values of the alignment signal.