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公开(公告)号：US08778270B2
公开(公告)日：2014-07-15
申请号：US13648081
申请日：2012-10-09
Applicant: Samsung Electronics Co., Ltd.
Inventor： Jong-myeon Park , Byung-chul Kim
IPC: G01N9/30
CPC classification number: G01N21/07 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2300/0806 , B01L2300/0864 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/0021 , F16K99/0063 , F16K2099/0074 , F16K2099/0076 , F16K2099/0084 , Y10T436/111666 , Y10T436/25375
Abstract: An apparatus for separating components and a method of separating components using the apparatus are provided. The apparatus includes: a main chamber which contains a sample that is separated into a plurality of layers by a centrifugal force; a component separating chamber which is connected to the main chamber, and receives a specific layer including specific components among the plurality of layers; a first channel which connects the component separating chamber to the main chamber; and a first channel valve which is disposed in the first channel to control a liquid flowing through the first channel.
Abstract translation: 提供了一种用于分离组件的装置和使用该装置分离组件的方法。 该装置包括：主室，其包含通过离心力分离成多个层的样品; 分离室，其连接到所述主室，并且在所述多个层中接收包括特定成分的特定层; 将部件分离室连接到主室的第一通道; 以及第一通道阀，其设置在第一通道中以控制流过第一通道的液体。
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12.发明申请NUCLEIC ACID STRUCTURE COMPLEX INCLUDING NUCLEIC ACIDS, RAMAN-ACTIVE MOLECULES, AND METAL PARTICLES, METHOD OF PREPARING THE SAME, AND METHOD OF DETECTING TARGET MATERIAL BY USING THE NUCLEIC ACID STRUCTURE COMPLEX 有权包含核酸，拉曼活性分子和金属颗粒的核酸结构复合物，其制备方法以及通过使用核酸结构复合物检测目标材料的方法公开(公告)号：US20140120629A1
公开(公告)日：2014-05-01
申请号：US14067825
申请日：2013-10-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Myoung-soon KIM , Jong-myeon Park , Jung-won Keum , Chang-eun Yoo
CPC classification number: C12Q1/6816 , G01N33/5308 , C12Q2563/149 , C12Q2563/179 , C12Q2565/632
Abstract: Provided are nucleic acid structures suitable for reproducible Raman spectroscopy, methods of preparing the same, and methods of detecting a target material using the nucleic acid structures, whereby various target materials may be analyzed by using reproducible Raman spectroscopy.
Abstract translation: 提供了适用于可重复拉曼光谱的核酸结构，其制备方法，以及使用核酸结构检测靶材料的方法，由此通过使用可再现的拉曼光谱分析各种靶材料。
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13.发明授权公开(公告)号：US09410127B2
公开(公告)日：2016-08-09
申请号：US13941117
申请日：2013-07-12
Applicant: Samsung Electronics Co., Ltd.
Inventor： Min Seok S Kim , Jong-myeon Park
CPC classification number: C12N5/0693 , B01L3/502753 , B01L2200/0621 , B01L2200/16 , B01L2300/0803 , B01L2300/0864 , B01L2400/0409 , B01L2400/0677 , B01L2400/086 , C12N15/1006
Abstract: A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference.
Abstract translation: 微流体装置包括：样品室，其由于离心力将样品分成第一流体层和第二流体层; 从样品室接收第一流体层的第一富集单元a形成第一微粒和第一目标材料的第一复合物，并且使用密度差从第一流体层分离第一络合物; 以及第二富集单元，其从所述样品室接收所述第二流体层，形成第二微粒和所述第二目标材料的第二配合物，并且使用密度差从所述第二流体层分离所述第二配合物。
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14.发明申请公开(公告)号：US20150140684A1
公开(公告)日：2015-05-21
申请号：US14334342
申请日：2014-07-17
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ga-hee KIM , Hyun-ju Kang , Ye-ryoung Yong , Jong-myeon Park
IPC: G01N33/548 , C08B37/08
CPC classification number: C08B37/0072 , G01N33/544
Abstract: A target affinity material comprising a biodegradable polymer, wherein the biodegradable polymer comprises one or more solid particles and one or more materials that specifically binds to a target, as well as related methods and kits.
Abstract translation: 包含可生物降解聚合物的靶亲和材料，其中所述生物可降解聚合物包含一种或多种固体颗粒和特异性结合靶的一种或多种材料，以及相关方法和试剂盒。
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15.发明申请COMPOSITION FOR DIAGNOSING LIVER CANCER AND METHODS OF DIAGNOSING LIVER CANCER AND OBTAINING INFORMATION FOR DIAGNOSING LIVER CANCER 有权用于诊断肝癌的组合物和诊断肝癌的方法以及用于诊断肝癌的获得信息公开(公告)号：US20150104879A1
公开(公告)日：2015-04-16
申请号：US14322570
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ye-ryoung YONG , Hyun-ju Kang , Ga-hee Kim , Kyung-hee Park , Jong-myeon Park
IPC: G01N33/574 , C07K16/30
CPC classification number: C07K16/303 , C07K16/2896
Abstract: Provided is method of diagnosing liver cancer in a subject, the method comprising contacting a sample from a subject with a substance that specifically binds to transmembrane emp24 domain trafficking protein 2 (TMED2), cluster of differentiation 43 (CD43), or any combination thereof on the surface of a microvesicle; and measuring the level of the substance bound to microvesicles in the sample; and related methods and compositions.
Abstract translation: 提供了一种在受试者中诊断肝癌的方法，所述方法包括使来自受试者的样品与特异性结合跨膜emp24结构域运输蛋白2（TMED2），分化簇43（CD43）或其任何组合的物质接触 微泡的表面; 并测量与样品中微泡结合的物质的含量; 以及相关方法和组成。
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Patent Agency Ranking
16.发明申请INTERPARTICLE SPACING MATERIAL INCLUDING NUCLEIC ACID STRUCTURES AND USE THEREOF 审中-公开颗粒间距材料，包括核酸结构及其用途公开(公告)号：US20140356857A1
公开(公告)日：2014-12-04
申请号：US14285870
申请日：2014-05-23
Applicant: Samsung Electronics Co., Ltd. , Sungkyunkwan University Foundation for Corporate Collaboration
Inventor： Myoung-soon KIM , Sung-ha Park , Jun-wye Lee , Jong-myeon Park , Nam Huh
IPC: G01N21/65
CPC classification number: G01N21/658
Abstract: Provided is an interparticle spacing material comprising a nucleic acid structure which comprises at least one nucleic acid lattice comprising a double helix domain; and at least one metal particle which is in contact with a plane of the nucleic acid lattice, in a direction extending obliquely or perpendicularly away from the plane; wherein the double helix domain comprises a hybridization area in which a single strand is hybridized with another single strand.
Abstract translation: 提供了一种颗粒间距材料，其包含核酸结构，其包含至少一个包含双螺旋结构域的核酸晶格; 以及至少一个与所述核酸晶格的平面接触的金属颗粒，在与所述平面倾斜或垂直的方向上延伸的方向; 其中双螺旋结构域包含其中单链与另一单链杂交的杂交区。
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公开(公告)号：US09903796B2
公开(公告)日：2018-02-27
申请号：US14323812
申请日：2014-07-03
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hun-joo Lee , Yeon-jeong Kim , Dong-hyun Park , Jong-myeon Park
IPC: G01N1/30
CPC classification number: G01N1/30 , G01N2001/305
Abstract: A photocleavable polymer comprising a photocleavable linker and a polymer having a functional group that binds to a protein, lipid, sugar of a cell, or any combination thereof, as well as a method of selectively lysing cells by incubating a sample comprising two or more cells with the photocleavable polymer to reversibly fix the cells; selectively irradiating the fixed cells or a target or non-target cell among the fixed cells to cleave the photocleavable polymer; and adding a cell lysis solution to selectively lyse the irradiated cells.
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公开(公告)号：US09624474B2
公开(公告)日：2017-04-18
申请号：US13949320
申请日：2013-07-24
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Jong-myeon Park
CPC classification number: C12N5/0693 , C07K16/30
Abstract: Provided is a method of separating a rare cell from a sample comprising incubating a sample comprising a rare cell and a second cell with a particle comprising a moiety capable of binding to the rare cell to form a complex comprising the particle and the rare cell; applying the mixture to a medium having a density gradient; and centrifuging the mixture to separate the complex from the second cell.
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19.发明授权公开(公告)号：US09518125B2
公开(公告)日：2016-12-13
申请号：US14322570
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ye-ryoung Yong , Hyun-ju Kang , Ga-hee Kim , Kyung-hee Park , Jong-myeon Park
CPC classification number: C07K16/303 , C07K16/2896
Abstract: Provided is method of diagnosing liver cancer in a subject, the method comprising contacting a sample from a subject with a substance that specifically binds to transmembrane emp24 domain trafficking protein 2 (TMED2), cluster of differentiation 43 (CD43), or any combination thereof on the surface of a microvesicle; and measuring the level of the substance bound to microvesicles in the sample; and related methods and compositions.
Abstract translation: 提供了一种在受试者中诊断肝癌的方法，所述方法包括使来自受试者的样品与特异性结合跨膜emp24结构域运输蛋白2（TMED2），分化簇43（CD43）或其任何组合的物质接触 微泡的表面; 并测量与样品中微泡结合的物质的含量; 以及相关方法和组成。
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20.发明授权Method of sequential and multiple immunostaining for detection of various antigens in the same specimens 有权用于检测同一标本中各种抗原的顺序和多次免疫染色方法公开(公告)号：US09383371B2
公开(公告)日：2016-07-05
申请号：US13935166
申请日：2013-07-03
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hun-joo Lee , Jin-ho Oh , Jong-myeon Park , Yeon-jeong Kim , Mi-jeong Song
IPC: C12Q1/68 , G01N33/53 , C12P19/34 , G01N33/00 , G01N33/566 , C07H21/02 , A61K38/00 , C07K1/00 , A61K39/395 , A61K39/00 , G01N33/68 , G01N33/574
CPC classification number: G01N33/6893 , G01N33/574 , G01N33/582
Abstract: Provided herein is a method of sequential and multiple immunostaining for detection of various antigens in the same specimens, which may be used for qualitative or quantitative analysis of proteins expressed, gene analysis, and morphological analysis even in specimens where only a small amount is available.
Abstract translation: 本文提供了用于检测相同标本中的各种抗原的顺序和多重免疫染色的方法，即使在仅少量可用的标本中，其也可用于表达蛋白质的定性或定量分析，基因分析和形态学分析。
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