-
公开(公告)号：US09903796B2
公开(公告)日：2018-02-27
申请号：US14323812
申请日：2014-07-03
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hun-joo Lee , Yeon-jeong Kim , Dong-hyun Park , Jong-myeon Park
IPC: G01N1/30
CPC classification number: G01N1/30 , G01N2001/305
Abstract: A photocleavable polymer comprising a photocleavable linker and a polymer having a functional group that binds to a protein, lipid, sugar of a cell, or any combination thereof, as well as a method of selectively lysing cells by incubating a sample comprising two or more cells with the photocleavable polymer to reversibly fix the cells; selectively irradiating the fixed cells or a target or non-target cell among the fixed cells to cleave the photocleavable polymer; and adding a cell lysis solution to selectively lyse the irradiated cells.
-
公开(公告)号：US09657345B2
公开(公告)日：2017-05-23
申请号：US13899223
申请日：2013-05-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Dong-hyun Park , Sung-woo Hong , Kyung-hee Park , Myo-yong Lee
CPC classification number: C12Q1/6876 , C12Q1/6844 , C12Q2525/207 , C12Q2525/307 , C12Q2531/119
Abstract: Provided is a dual-hybridization polynucleotide including a first complementary region that is complementary to the 3′-terminus of a target nucleic and a second complementary region that is complementary to the 5′-terminus of the target nucleic acid, a composition and kit including the polynucleotide, and a method of producing a nucleotide sequence complementary to the target nucleic acid. The first complementary region to be bound at the 3′-terminus of the target nucleic acid can be shortened and the target nucleic acid may be amplified with excellent specificity and/or sensitivity.
-
公开(公告)号：US09828645B2
公开(公告)日：2017-11-28
申请号：US15425120
申请日：2017-02-06
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung-hee Park , Ye-ryoung Yong , Hyun-ju Kang , Ga-hee Kim , Dong-hyun Park , Myo-yong Lee
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The composition or kit includes a polynucleotide that is the same as or complementary to at least one microRNA (miRNA) selected from the group consisting of hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c in a vesicle, or a fragment of the microRNA.
-
公开(公告)号：US20150044725A1
公开(公告)日：2015-02-12
申请号：US14222314
申请日：2014-03-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Chang-eun YOO , Yeon-jeong Kim , Dong-hyun Park , Kyung-yeon Han
IPC: C12Q1/68
CPC classification number: C12N15/1013 , C12N15/1006
Abstract: A method of separating nucleic acids from cells, the method comprising incubating a sample comprising cells with a solid substrate that binds to the cells, whereby the cells adhere to the solid substrate; suspending the solid substrate adhered to the cells in a lysis composition comprising about 100 mM to about 300 mM of alkaline metal salt, and having a pH of about 6 to about 8; lysing the cells in the lysis composition to obtain a lysed solution; and obtaining the nucleic acids from the lysed solution; as well as related compositions and kits.
Abstract translation: 一种从细胞中分离核酸的方法，所述方法包括将包含细胞的样品与固定于细胞上的固体底物孵育，由此所述细胞粘附到固体基质上; 将固体底物悬浮在包含约100mM至约300mM碱金属盐并且pH为约6至约8的裂解组合物中的细胞上; 裂解裂解组合物中的细胞以获得裂解溶液; 从裂解的溶液中获得核酸; 以及相关组合物和试剂盒。
-
公开(公告)号：US20170145519A1
公开(公告)日：2017-05-25
申请号：US15425120
申请日：2017-02-06
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung-hee Park , Ye-ryoung Yong , Hyun-ju Kang , Ga-hee Kim , Dong-hyun Park , Myo-yong Lee
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The composition or kit includes a polynucleotide that is the same as or complementary to at least one microRNA (miRNA) selected from the group consisting of hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c in a vesicle, or a fragment of the microRNA.
-
Patent Agency Ranking
6.发明申请COMPOSITION AND KIT FOR SEPARATING CANCER CELL, AND METHOD OF SEPARATING CANCER CELL BY USING THE COMPOSITION AND KIT 审中-公开用于分离癌细胞的组合物和试剂盒，以及使用组合物和试剂盒分离癌细胞的方法公开(公告)号：US20150064721A1
公开(公告)日：2015-03-05
申请号：US14252284
申请日：2014-04-14
Inventor： Yeon-jeong KIM , Kyung-yeon Han , You-Sun Kim , Hui-sung Moon , Dong-hyun Park , Jong-myeon Park
IPC: G01N33/574 , C07K16/30 , C07K16/40
CPC classification number: G01N33/57492 , C07K16/2851 , C07K16/30 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N2333/70596
Abstract: Provided is a composition and a kit for separating a cancer stem cell or a circulating tumor cell, a method of separating a cancer stem cell or a circulating tumor cell in a biological sample, and a method for diagnosing metastatic cancer.
Abstract translation: 提供了用于分离癌症干细胞或循环肿瘤细胞的组合物和试剂盒，分离生物样品中的癌症干细胞或循环肿瘤细胞的方法，以及诊断转移性癌症的方法。
-
7.发明申请COMPOSITION AND KIT FOR DIAGNOSING BREAST CANCER INCLUDING POLYNUCLEOTIDE WITHIN VESICLE, AND METHOD OF DIAGNOSING BREAST CANCER USING THE SAME 有权用于诊断包括在囊内的多核苷酸的乳腺癌的组合物和试剂盒，以及使用该方法诊断乳腺癌的方法公开(公告)号：US20140178885A1
公开(公告)日：2014-06-26
申请号：US14132964
申请日：2013-12-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung-hee PARK , Ye-ryoung Yong , Hyun-ju Kang , Ga-hee Kim , Dong-hyun Park , Myo-yong Lee
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The composition or kit includes a polynucleotide that is the same as or complementary to at least one microRNA (miRNA) selected from the group consisting of hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c in a vesicle, or a fragment of the microRNA.
Abstract translation: 提供乳腺癌诊断组合物和试剂盒，以及通过使用该组合物或试剂盒诊断乳腺癌或获取乳腺癌诊断信息的方法。 该组合物或试剂盒包括与选自hsa-miR-126，hsa-miR-23a，hsa-miR-24，hsa-miR- 19b，hsa-miR-103，hsa-miR-142-3p，hsa-miR-144，hsa-miR-15a，hsa-miR-185，hsa-miR-93和hsa-miR-30c， 或微小RNA的片段。
-
8.发明授权Composition and kit for diagnosing breast cancer including polynucleotide within vesicle, and method of diagnosing breast cancer using the same 有权用于诊断乳腺癌的组合物和试剂盒，包括囊泡内的多核苷酸，以及使用该乳腺癌诊断乳腺癌的方法公开(公告)号：US09593379B2
公开(公告)日：2017-03-14
申请号：US14132964
申请日：2013-12-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung-hee Park , Ye-ryoung Yong , Hyun-ju Kang , Ga-hee Kim , Dong-hyun Park , Myo-yong Lee
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The composition or kit includes a polynucleotide that is the same as or complementary to at least one microRNA (miRNA) selected from the group consisting of hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c in a vesicle, or a fragment of the microRNA.
Abstract translation: 提供乳腺癌诊断组合物和试剂盒，以及通过使用该组合物或试剂盒诊断乳腺癌或获取乳腺癌诊断信息的方法。 该组合物或试剂盒包括与选自hsa-miR-126，hsa-miR-23a，hsa-miR-24，hsa-miR- 19b，hsa-miR-103，hsa-miR-142-3p，hsa-miR-144，hsa-miR-15a，hsa-miR-185，hsa-miR-93和hsa-miR-30c， 或微小RNA的片段。
-
公开(公告)号：US09523118B2
公开(公告)日：2016-12-20
申请号：US14189762
申请日：2014-02-25
Applicant: Samsung Electronics Co., Ltd.
Inventor： Dong-hyun Park , Yeon-jeong Kim , Kyung-yeon Han
IPC: C12Q1/68
CPC classification number: C12Q1/6858 , C12Q2537/163
Abstract: Provided are a composition or a kit for detecting a nucleic acid with genetic variation including a first amplification blocking nucleic acid and a second amplification blocking nucleic acid, and a method of detecting a nucleic acid with genetic variation by using the same. Based on the above, a nucleic acid with genetic variation can be detected with high sensitivity and accuracy.
Abstract translation: 提供了用于检测具有遗传变异的核酸的组合物或试剂盒，包括第一扩增阻断核酸和第二扩增阻断核酸，以及通过使用该核酸检测具有遗传变异的核酸的方法。 基于上述，可以以高灵敏度和准确度检测出具有遗传变异的核酸。
-
公开(公告)号：US09193994B2
公开(公告)日：2015-11-24
申请号：US13866655
申请日：2013-04-19
Applicant: Samsung Electronics Co., Ltd.
Inventor： Dong-hyun Park , Sung-woo Hong , Myo-yong Lee
CPC classification number: C12Q1/6853 , C12Q1/6844 , C12Q2525/161 , C12Q2525/185
Abstract: A first polynucleotide including at least two complementary regions that are complementary to a target nucleic acid and have a reverse configuration, a second polynucleotide complementary to the first polynucleotide, and uses thereof, are provided.
Abstract translation: 提供了包含与靶核酸互补并具有反向构型的至少两个互补区的第一多核苷酸，与第一多核苷酸互补的第二个多核苷酸及其用途。
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.017 seconds)
