公开(公告)号：US09657345B2

公开(公告)日：2017-05-23

申请号：US13899223

申请日：2013-05-21

Applicant: Samsung Electronics Co., Ltd.

Inventor： Dong-hyun Park ,  Sung-woo Hong ,  Kyung-hee Park ,  Myo-yong Lee

IPC: C12Q1/68 ,  C07H21/00 ,  C12P19/34

CPC classification number: C12Q1/6876 ,  C12Q1/6844 ,  C12Q2525/207 ,  C12Q2525/307 ,  C12Q2531/119

Abstract: Provided is a dual-hybridization polynucleotide including a first complementary region that is complementary to the 3′-terminus of a target nucleic and a second complementary region that is complementary to the 5′-terminus of the target nucleic acid, a composition and kit including the polynucleotide, and a method of producing a nucleotide sequence complementary to the target nucleic acid. The first complementary region to be bound at the 3′-terminus of the target nucleic acid can be shortened and the target nucleic acid may be amplified with excellent specificity and/or sensitivity.

公开(公告)号：US09193994B2

公开(公告)日：2015-11-24

申请号：US13866655

申请日：2013-04-19

Applicant: Samsung Electronics Co., Ltd.

Inventor： Dong-hyun Park ,  Sung-woo Hong ,  Myo-yong Lee

IPC: C12Q1/68 ,  C12P19/34 ,  C07H21/00

CPC classification number: C12Q1/6853 ,  C12Q1/6844 ,  C12Q2525/161 ,  C12Q2525/185

Abstract: A first polynucleotide including at least two complementary regions that are complementary to a target nucleic acid and have a reverse configuration, a second polynucleotide complementary to the first polynucleotide, and uses thereof, are provided.

Abstract translation: 提供了包含与靶核酸互补并具有反向构型的至少两个互补区的第一多核苷酸，与第一多核苷酸互补的第二个多核苷酸及其用途。