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11.发明申请公开(公告)号：US20250002836A1
公开(公告)日：2025-01-02
申请号：US18739573
申请日：2024-06-11
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Tokio TAKAGI , Toyohiko YAMAUCHI , Tatsuo DOUGAKIUCHI , Yoichi KAWADA , Yoshiyuki SHIMIZU , Gen TAKEBE
Abstract: A cell sample evaluation apparatus includes an evaluation light irradiation unit for irradiating an irradiation region set in a culture region of a plurality of cells in an object cell sample with evaluation light having a wavelength in a mid-infrared region under a predetermined irradiation condition, a dead cell number measurement unit for measuring a dead cell number generated according to an irradiation amount of the evaluation light in the irradiation region of the object cell sample, and a culture state analysis unit for evaluating a culture state of the object cell sample by obtaining an object correlation between the irradiation amount of the evaluation light and the dead cell number for the object cell sample and comparing a reference correlation between the irradiation amount of the evaluation light and the dead cell number for a reference cell sample and the object correlation.
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公开(公告)号：US20190064209A1
公开(公告)日：2019-02-28
申请号：US16106134
申请日：2018-08-21
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yoichi KAWADA , Hironori TAKAHASHI , Jun TAKEDA , Ikufumi KATAYAMA , Yusuke ARASHIDA , Katsumasa YOSHIOKA
Abstract: A tunnel current control apparatus includes a terahertz wave generation element configured to generate and output a terahertz wave pulse, a CEP adjustment unit configured to adjust a CEP of the terahertz wave pulse, and an off-axis parabolic mirror serving as a focusing element configured to focus the terahertz wave pulse in a gap between a first conductive object and a second conductive object. The CEP adjustment unit can arbitrarily adjust the CEP of the terahertz wave pulse.
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13.发明申请公开(公告)号：US20190025124A1
公开(公告)日：2019-01-24
申请号：US16039163
申请日：2018-07-18
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Takashi YASUDA , Yoichi KAWADA , Kazuki HORITA , Hironori TAKAHASHI , Takayoshi KUGA , Atsushi NAKANISHI , Kazutaka TOMARI
IPC: G01J3/42 , G01J3/02 , G01N21/3586
Abstract: A measurement auxiliary member is placed on an arrangement surface of a prism. A measurement object is placed on an upper surface of the measurement auxiliary member. The measurement auxiliary member totally reflects the terahertz wave input from a lower surface by the upper surface and outputs the totally-reflected terahertz wave from the lower surface. A main pulse of a terahertz wave totally reflected by the upper surface of the measurement auxiliary member without multiply-reflected inside any optical element on an optical path of the terahertz wave, and a noise pulse of a terahertz wave multiply-reflected inside any optical element on the optical path and reflected on an interface between the prism and the measurement auxiliary member, are temporally separated from each other when detecting a correlation by a terahertz wave detection element.
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公开(公告)号：US20160313182A1
公开(公告)日：2016-10-27
申请号：US15131390
申请日：2016-04-18
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yoichi KAWADA , Yoshiyuki SHIMIZU , Toyohiko YAMAUCHI
CPC classification number: G01J3/0229 , G01J3/42 , G01J2003/1213 , G01N2021/3595
Abstract: A spectroscopic measurement apparatus includes a light source, a diffraction grating being a spectroscopic unit, a spatial filter unit, a detection unit, and an analysis unit. The diffraction grating spatially disperses light from the light source, and outputs the light to different optical paths according to a wavelength. The spatial filter unit inputs the light from the diffraction grating to different positions according to the wavelength, applies loss depending on the wavelength to the light, and outputs the light. The detection unit detects the intensity of the light from the spatial filter unit. The analysis unit obtains the intensities of light in an absorption band and light in a non-absorption band of a component in a measurement sample on an optical path between the light source and the detection unit based on the detection result, and evaluates the component in the measurement sample.
Abstract translation: 光谱测量装置包括光源，衍射光栅是分光单元，空间滤光单元，检测单元和分析单元。 衍射光栅在空间上分散来自光源的光，并根据波长将光输出到不同的光路。 空间滤波器单元根据波长将来自衍射光栅的光输入到不同的位置，根据对光的波长施加损耗，并输出光。 检测单元检测来自空间滤波器单元的光的强度。 分析单元基于检测结果，在光源和检测单元之间的光路上获得吸收带中的光的强度和测量样本中的成分的非吸收带中的光，并且评估其中的分量 测量样品。
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公开(公告)号：US20160154176A1
公开(公告)日：2016-06-02
申请号：US14906924
申请日：2014-05-20
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yoichi KAWADA , Takashi YASUDA , Atsushi NAKANISHI
Abstract: A wave plate comprising: a prism member having an entrance surface for receiving a terahertz wave T, and an exit surface for emitting the terahertz wave T received by the entrance surface; wherein the prism member is constituted by a plurality of waveguide regions having: a partial entrance surface for receiving a part of the terahertz wave T, a plurality of total reflection surfaces for totally reflecting the terahertz wave T from the partial entrance surface, and a partial exit surface for emitting the terahertz wave T totally reflected from the total reflection surfaces; and each of the partial entrance surfaces combine to constitute the entrance surface of the prism member, and each of the partial exit surfaces combine to constitute the exit surface of the prism member, by stacking waveguide regions.
Abstract translation: 一种波片，包括：具有用于接收太赫兹波T的入射表面的棱镜构件和用于发射由入射表面接收的太赫兹波T的出射表面; 其中所述棱镜部件由多个波导区域构成，所述多个波导区域具有用于接收太赫兹波T的一部分的部分入射面，用于从所述部分入射面全面反射太赫兹波T的多个全反射面， 出射面，用于发射从全反射面全反射的太赫兹波; 并且每个部分入射面组合成构成棱镜构件的入射面，并且通过堆叠波导区域，各部分出射面组合成构成棱镜构件的出射面。
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Patent Agency Ranking
16.发明公开公开(公告)号：US20240175811A1
公开(公告)日：2024-05-30
申请号：US18283296
申请日：2022-01-31
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Kazuki HORITA , Kouichiro AKIYAMA , Yoichi KAWADA , Hiroshi SATOZONO
IPC: G01N21/3577 , G01N1/44
CPC classification number: G01N21/3577 , G01N1/44
Abstract: An ATR apparatus includes a prism having a reflection surface, a holding unit holding a sample including a suspension on the reflection surface, and an adjustment unit adjusting a fluidal state of the sample held on the reflection surface. The adjustment unit adjusts the fluidal state of the sample to a first fluidal state in order to acquire a first detection result relating to the sample in the first fluidal state and adjusts the fluidal state of the sample to a second fluidal state in order to acquire a second detection result relating to the sample in the second fluidal state.
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公开(公告)号：US20200150339A1
公开(公告)日：2020-05-14
申请号：US16739214
申请日：2020-01-10
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yoichi KAWADA , Takashi YASUDA , Atsushi NAKANISHI
Abstract: A wave plate comprising: a prism member having an entrance surface for receiving a terahertz wave T, and an exit surface for emitting the terahertz wave T received by the entrance surface; wherein the prism member is constituted by a plurality of waveguide regions having: a partial entrance surface for receiving a part of the terahertz wave T, a plurality of total reflection surfaces for totally reflecting the terahertz wave T from the partial entrance surface, and a partial exit surface for emitting the terahertz wave T totally reflected from the total reflection surfaces; and each of the partial entrance surfaces combine to constitute the entrance surface of the prism member, and each of the partial exit surfaces combine to constitute the exit surface of the prism member, by stacking waveguide regions.
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公开(公告)号：US20190064210A1
公开(公告)日：2019-02-28
申请号：US16108447
申请日：2018-08-22
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yoichi KAWADA , Hironori TAKAHASHI , Jun TAKEDA , Ikufumi KATAYAMA , Yusuke ARASHIDA , Katsumasa YOSHIOKA
Abstract: A tunnel current control apparatus includes a light source, a branching unit, a chopper, an optical path difference adjustment unit, a polarizer, a terahertz wave generation element, a CEP adjustment unit, a terahertz wave detection element, a quarter-wave plate, a polarization separation element, photodetectors, a differential amplifier, a lock-in amplifier, a current measurement unit, a processing unit, mirrors, and off-axis parabolic mirrors. The CEP adjustment unit can arbitrarily adjust a CEP of a terahertz wave pulse. The processing unit obtains a conversion filter used for conversion from an electric field waveform of a far field of the terahertz wave pulse to an electric field waveform of a near field based on a tunnel current measured by the current measurement unit and a correlation detected by the terahertz wave detection element.
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19.发明申请公开(公告)号：US20170248833A1
公开(公告)日：2017-08-31
申请号：US15505963
申请日：2015-08-28
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Kouichiro AKIYAMA , Yoichi KAWADA , Takashi YASUDA , Atsushi NAKANISHI , Hironori TAKAHASHI
IPC: G02F1/361 , G02F1/355 , G01N21/3581
CPC classification number: G02F1/3612 , C07C309/30 , C07D213/38 , G01N21/3581 , G02F1/3551 , G02F1/3613
Abstract: Disclosed is a non-linear optical crystal containing pyridinium represented by the following Formula (1), 4-substituted phenylsulfonate represented by the following Formula (2a), and 2,4,6-substituted phenylsulfonate represented by the following Formula (2b).
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公开(公告)号：US20130187050A1
公开(公告)日：2013-07-25
申请号：US13742616
申请日：2013-01-16
Applicant: Hamamatsu Photonics K.K.
Inventor： Gen TAKEBE , Yoichi KAWADA , Kouichiro AKIYAMA
IPC: G01N21/35
CPC classification number: G01N21/3577 , G01N21/3563 , G01N21/3586 , G01N21/552
Abstract: The drug evaluation device obtains, by an attenuated reflection method using a terahertz wave, an evaluation absorption spectrum for a frequency with respect to a liquid to be evaluated. When crystalline particles are suspended in a liquid, an absorption peak having a peak area corresponding to the amount of suspension appears in its absorption spectrum. Therefore, whether or not and by what ratio crystalline particles are suspended in the liquid can be determined according to whether or not the absorption peak exists and the peak area. When amorphous particles are suspended in the liquid, the baseline of its absorption spectrum lowers according to the ratio of amorphous particles suspended in the liquid. Therefore, whether or not and by what ratio amorphous particles are suspended in the liquid can be determined according to the lowering amount of the baseline.
Abstract translation: 药物评价装置通过使用太赫兹波的衰减反射法获得关于待评价液体的频率的评价吸收光谱。 当结晶颗粒悬浮在液体中时，具有对应于悬浮液量的峰面积的吸收峰出现在其吸收光谱中。 因此，可以根据是否存在吸收峰和峰面积来确定晶体颗粒悬浮在液体中的比例和比例。 当无定形颗粒悬浮在液体中时，其吸收光谱的基线根据悬浮在液体中的无定形颗粒的比例而降低。 因此，可以根据基线的降低量来确定无定形颗粒悬浮在液体中的比例和比例。
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