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公开(公告)号:US20250102429A1
公开(公告)日:2025-03-27
申请号:US18725845
申请日:2022-12-02
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kouichiro AKIYAMA , Hiroshi SATOZONO
IPC: G01N21/3581
Abstract: There is provided an optical member for terahertz. The optical member is constituted by a molded body containing a mixture of an organic nonlinear optical material and an excipient. There is also provided an optical element including: the optical member; and a support member configured to support the optical member. There is also provided a method for manufacturing an optical member for terahertz. The method includes: a first process of mixing an organic nonlinear optical material and an excipient to form a mixture; and a second process of forming a molded body of the mixture by applying a pressure to the mixture after the first process.
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公开(公告)号:US20240418641A1
公开(公告)日:2024-12-19
申请号:US18703413
申请日:2022-10-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuhiro TAKAHASHI , Kouichiro AKIYAMA , Hiroshi SATOZONO
IPC: G01N21/3581 , G01N21/3563
Abstract: A crystal form determination method includes a first process of preparing a measurement target object; a second process of entering a terahertz wave to the measurement target object and detecting the terahertz wave from the measurement target object to acquire a plurality of detection results corresponding to a plurality of times separated from each other; and a third process of determining a type of crystal form contained in the measurement target object. In the third process, when a frequency characteristic having a third peak at a third frequency different from a first frequency related to a first peak corresponding to an anhydride and a second frequency related to a second peak corresponding to a hydrate exists among the plurality of frequency characteristics, determination is made that the crystal form different from the anhydride and the hydrate is contained in the measurement target object.
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公开(公告)号:US20240142360A1
公开(公告)日:2024-05-02
申请号:US18280497
申请日:2022-03-24
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuhiro TAKAHASHI , Kouichiro AKIYAMA , Hiroshi SATOZONO
CPC classification number: G01N15/042 , G01N2015/0053 , G01N2015/045
Abstract: A dispersion stability evaluation method is a method for evaluating a dispersion stability of dispersoid dispersed in a dispersion medium. The dispersion stability evaluation method includes a first step of holding a sample including the dispersion medium and the dispersoid on a reflective surface, and a second step of causing terahertz waves to be incident on the reflective surface from a side opposite to the sample and detecting the terahertz waves reflected by the reflective surface. In the second step, while a state where the dispersoid are allowed to move toward the reflective surface is maintained, a plurality of detection results respectively corresponding to a plurality of times apart from each other are acquired.
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公开(公告)号:US20200173916A1
公开(公告)日:2020-06-04
申请号:US16701242
申请日:2019-12-03
Inventor: Kouichiro AKIYAMA , Kazuki HORITA , Hironori TAKAHASHI , Hiroshi SATOZONO , Tomoaki SAKAMOTO
IPC: G01N21/3581 , G01N21/55
Abstract: A fermentation state monitoring apparatus includes: a terahertz wave generation element that outputs inspection light using a terahertz wave to a fermented food under fermentation in a sealed product container; a terahertz wave detection element that detects return light of the inspection light reflected by the fermented food in the product container; and a determination unit that determines a fermentation progress of the fermented food based on an index value including a reflectance of the return light with respect to the inspection light or an absorption coefficient of the return light with respect to the inspection light.
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公开(公告)号:US20240175811A1
公开(公告)日:2024-05-30
申请号:US18283296
申请日:2022-01-31
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuki HORITA , Kouichiro AKIYAMA , Yoichi KAWADA , Hiroshi SATOZONO
IPC: G01N21/3577 , G01N1/44
CPC classification number: G01N21/3577 , G01N1/44
Abstract: An ATR apparatus includes a prism having a reflection surface, a holding unit holding a sample including a suspension on the reflection surface, and an adjustment unit adjusting a fluidal state of the sample held on the reflection surface. The adjustment unit adjusts the fluidal state of the sample to a first fluidal state in order to acquire a first detection result relating to the sample in the first fluidal state and adjusts the fluidal state of the sample to a second fluidal state in order to acquire a second detection result relating to the sample in the second fluidal state.
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公开(公告)号:US20230258620A1
公开(公告)日:2023-08-17
申请号:US18095575
申请日:2023-01-11
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Tetsuya UCHIDA , Kouichiro AKIYAMA , Hiroshi SATOZONO , Tomoyuki HAKAMATA
IPC: G01N33/24 , G01N21/552 , G01N21/3581
CPC classification number: G01N33/246 , G01N21/552 , G01N21/3581
Abstract: A hygroscopicity evaluation method includes: a first step of preparing a first sample and a second sample; a second step of acquiring a first detection result for the first sample and a second detection result for the second sample by making a terahertz wave incident on each of the first and second samples; and a third step of evaluating the hygroscopicity of a measurement target object based on a first frequency characteristic calculated from the first detection result and a second frequency characteristic calculated from the second detection result. In the third step, the magnitude of the hygroscopicity of the measurement target object is evaluated based on the difference between the magnitude of a first peak of the first frequency characteristic in a reference frequency range and the magnitude of a second peak of the second frequency characteristic in the reference frequency range.
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公开(公告)号:US20220091027A1
公开(公告)日:2022-03-24
申请号:US17474338
申请日:2021-09-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuhiro TAKAHASHI , Kouichiro AKIYAMA , Hiroshi SATOZONO
IPC: G01N21/3563 , G01N21/552
Abstract: A terahertz wave attenuated total reflection spectroscopic method, includes: a first step of disposing a measurement target of which a volume is changed during a measurement period on a reflection surface; and a second step of acquiring data including a plurality of detection results respectively corresponding to a plurality of times separated from each other during the measurement period by allowing a terahertz wave to be incident on the reflection surface from a side opposite to the measurement target and by detecting the terahertz wave reflected on the reflection surface, during the measurement period. In the second step, a state in which a substantially constant pressure is applied to the measurement target disposed on the reflection surface is maintained during the measurement period.
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公开(公告)号:US20170248833A1
公开(公告)日:2017-08-31
申请号:US15505963
申请日:2015-08-28
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kouichiro AKIYAMA , Yoichi KAWADA , Takashi YASUDA , Atsushi NAKANISHI , Hironori TAKAHASHI
IPC: G02F1/361 , G02F1/355 , G01N21/3581
CPC classification number: G02F1/3612 , C07C309/30 , C07D213/38 , G01N21/3581 , G02F1/3551 , G02F1/3613
Abstract: Disclosed is a non-linear optical crystal containing pyridinium represented by the following Formula (1), 4-substituted phenylsulfonate represented by the following Formula (2a), and 2,4,6-substituted phenylsulfonate represented by the following Formula (2b).
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公开(公告)号:US20130187050A1
公开(公告)日:2013-07-25
申请号:US13742616
申请日:2013-01-16
Applicant: Hamamatsu Photonics K.K.
Inventor: Gen TAKEBE , Yoichi KAWADA , Kouichiro AKIYAMA
IPC: G01N21/35
CPC classification number: G01N21/3577 , G01N21/3563 , G01N21/3586 , G01N21/552
Abstract: The drug evaluation device obtains, by an attenuated reflection method using a terahertz wave, an evaluation absorption spectrum for a frequency with respect to a liquid to be evaluated. When crystalline particles are suspended in a liquid, an absorption peak having a peak area corresponding to the amount of suspension appears in its absorption spectrum. Therefore, whether or not and by what ratio crystalline particles are suspended in the liquid can be determined according to whether or not the absorption peak exists and the peak area. When amorphous particles are suspended in the liquid, the baseline of its absorption spectrum lowers according to the ratio of amorphous particles suspended in the liquid. Therefore, whether or not and by what ratio amorphous particles are suspended in the liquid can be determined according to the lowering amount of the baseline.
Abstract translation: 药物评价装置通过使用太赫兹波的衰减反射法获得关于待评价液体的频率的评价吸收光谱。 当结晶颗粒悬浮在液体中时,具有对应于悬浮液量的峰面积的吸收峰出现在其吸收光谱中。 因此,可以根据是否存在吸收峰和峰面积来确定晶体颗粒悬浮在液体中的比例和比例。 当无定形颗粒悬浮在液体中时,其吸收光谱的基线根据悬浮在液体中的无定形颗粒的比例而降低。 因此,可以根据基线的降低量来确定无定形颗粒悬浮在液体中的比例和比例。
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