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11.发明公开公开(公告)号：US20240310381A1
公开(公告)日：2024-09-19
申请号：US18575123
申请日：2022-06-24
发明人： Hyun Woo RHEE , Jae Myoung SUH , Jong-Seo KIM , Isaac PARK , Kwang-eun KIM
IPC分类号： G01N33/68 , A01K67/0275 , C12N9/08 , C12N15/85
CPC分类号： G01N33/6848 , A01K67/0275 , C12N9/0065 , C12N15/8509 , A01K2227/105 , C07K2319/07 , C12Y111/01011
摘要： The present invention relates to a transgenic animal in which APEX2 is specifically expressed in a mitochondrial matrix and to uses thereof. When the transgenic animal according to the present invention is used, it is possible to overcome the limitation of being susceptible to contamination with proteins derived from other organelles or other tissue cells in existing mitochondrial proteomic studies. Accordingly, mitochondrial matrix proteomic research with a high reliability is possible, tissue-specific mitochondrial matrix proteomics can easily be analyzed, and a wide range of applications are possible in basic life science research, drug development, and diagnostic research related to mitochondrial proteomics.
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公开(公告)号：US12096043B2
公开(公告)日：2024-09-17
申请号：US18298711
申请日：2023-04-11
发明人： Mun Churl Kim , Bum Shik Lee , Jae Il Kim , Chang Seob Park , Sang Jin Hahm , In Joon Cho , Keun Sik Lee , Byung Sun Kim
IPC分类号： H04N19/86 , H04N19/103 , H04N19/117 , H04N19/122 , H04N19/124 , H04N19/13 , H04N19/14 , H04N19/159 , H04N19/176 , H04N19/61 , H04N19/80 , H04N19/172 , H04N19/174 , H04N19/182
CPC分类号： H04N19/86 , H04N19/103 , H04N19/117 , H04N19/122 , H04N19/124 , H04N19/13 , H04N19/14 , H04N19/159 , H04N19/176 , H04N19/61 , H04N19/80 , H04N19/172 , H04N19/174 , H04N19/182
摘要： Disclosed are a method of encoding a division block in video encoding and a method of decoding a division block in video decoding. An input picture is divided into encoding unit blocks. The encoding unit blocks are divided into sub-blocks. The sub-blocks are encoded by selectively using at least one of intra prediction encoding and inter prediction encoding. A decoding process is performed through a reverse process of the encoding method. When pixel values of an encoding unit block are encoded in video encoding, the flexibility in selecting an encoding mode is increased and the efficiency of encoding is increased.
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公开(公告)号：US12091699B2
公开(公告)日：2024-09-17
申请号：US17586234
申请日：2022-01-27
发明人： Jin Woo Kim , Jun Woo Park
IPC分类号： C12P21/02
CPC分类号： C12P21/02
摘要： A composition for enhancing the production of a homeoprotein includes an inhibitor of lysosomal function. A method for enhancing the production of a homeoprotein, includes treating cells with an inhibitor of lysosomal function, a method for producing an animal cell line continuously expressing a homeoprotein and a method for mass-producing a homeoprotein using the animal cell line.
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公开(公告)号：US12091448B2
公开(公告)日：2024-09-17
申请号：US18089393
申请日：2022-12-27
发明人： Jin Woo Kim , Eun Jung Lee
CPC分类号： C07K16/18 , C12N15/86 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C12N2750/14143
摘要： The present disclosure relates to a PROX1 (Prospero homeobox protein 1) protein binding molecule. More specifically, the binding molecule of the present disclosure relates to a binding molecule having excellent binding ability to the PROX1 protein and having an excellent neutralizing effect on the PROX1 protein, and it is very useful for diagnosis, prevention or treatment of retinal neurodegenerative diseases.
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15.发明公开公开(公告)号：US20240304826A1
公开(公告)日：2024-09-12
申请号：US18514109
申请日：2023-11-20
发明人： In Yu Park , Jong Kil Oh , Woo Chul Jung , Seung Hyun Kim , Dong Hwan Oh
CPC分类号： H01M4/8892 , H01M4/8817 , H01M4/9016 , H01M4/92
摘要： A highly durable electrolyte membrane using cerium oxide supported with an alloy catalyst that is a hydrogen-oxygen reaction catalyst for improving chemical durability of an electrolyte membrane increases durability of a membrane-electrode assembly including the same and decreases the manufacturing cost thereof.
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公开(公告)号：US12084643B2
公开(公告)日：2024-09-10
申请号：US17082344
申请日：2020-10-28
发明人： Hyunjoo Lee , Chaeyun Shim , Yehhyun Jo , Kiup Kim , Joo-Hyeon Lee , Eunyoung Jang
CPC分类号： C12M23/26 , B01L3/505 , C12M23/12 , C12M41/00 , B01L2200/12 , B01L2300/0609 , B01L2300/0848 , B01L2300/123
摘要： An apparatus for measuring an electrophysiological signal of a three-dimensional (3D) cell and a method of fabricating the apparatus. The apparatus includes a flexible substrate including a plurality of protrusions, and a conductor formed on the plurality of protrusions, and regions other than the plurality of protrusions are partially removed from the flexible substrate.
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公开(公告)号：US20240292162A1
公开(公告)日：2024-08-29
申请号：US18573839
申请日：2021-11-19
发明人： Woojin Ahn , Kyousik Min , Hoseung Lee , Minkyu Je
CPC分类号： H04R25/505 , A61N1/0541 , A61N1/36039 , A61N1/36157 , A61N1/37252 , H04R25/606
摘要： The present disclosure discloses a method for improving an effective dynamic range including acquiring a hearing profile of a user, setting a section between a T level and a C level as a target range of a stimulation current for each of a plurality of electrodes included in an electrode array of a cochlear implant system based on the hearing profile, and mapping a plurality of current levels to an output current within the target range.
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公开(公告)号：US20240290356A1
公开(公告)日：2024-08-29
申请号：US18586642
申请日：2024-02-26
发明人： Junyong NOH , Dawon LEE , Jung Eun YOO , Kyungmin CHO , Bumki KIM , GyeongHun IM
IPC分类号： G11B27/031 , G06V20/40 , G06V40/16 , G11B27/10
CPC分类号： G11B27/031 , G06V20/46 , G06V20/49 , G06V40/171 , G11B27/10
摘要： Disclosed is an apparatus for generating a cross-edited video and a method of operating the apparatus. The method includes: obtaining a plurality of videos; sequentially generating video pieces such that one of the plurality of videos is played according to a timeline, based on a first transition reward that is based on a similarity between a video before a transition and a video after the transition in a specific frame and a continuous play time and on a second transition reward that is based on an elapsed time from a previous transition point; and generating a cross-edited video by connecting the video pieces.
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19.发明公开公开(公告)号：US20240270914A1
公开(公告)日：2024-08-15
申请号：US18568984
申请日：2022-10-12
发明人： Byeong-Soo BAE , Yung LEE
IPC分类号： C08J5/24 , B29C70/12 , B29C70/54 , B29K83/00 , B29K277/00 , B29K309/08
CPC分类号： C08J5/244 , B29C70/12 , B29C70/545 , C08J5/246 , B29K2083/00 , B29K2277/10 , B29K2309/08 , B29K2995/0046 , B29K2995/0077 , C08J2383/04
摘要： The present invention provides a fiber-reinforced composite film with omnidirectional stretchability on which an auxetic structure 100 is formed integrally with the film on a film, wherein the auxetic structure 100 comprises a plurality of space regions 130 in the form of single closed curves regularly arranged on the film; an island 120 formed surrounded by the space region 130; and a connection portion 110 formed at regular intervals by the space region 130 to connect adjacent islands 120; wherein the film, island 120 and connection portion 110 are plastic materials reinforced with fibers wherein the space region 130 is filled with the elastic auxiliary member 20 and a manufacturing method thereof.
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公开(公告)号：US20240261366A1
公开(公告)日：2024-08-08
申请号：US18427249
申请日：2024-01-30
发明人： Hail KIM , Hoeyune JUNG , Kyun Hoo KIM , Joonyub LEE , Hyeonkyu LEE , Heon Jong LEE
摘要： A method and composition for treating and/or preventing β-cell dysfunction and/or protecting impaired β-cells are disclosed. The method includes administering an effective amount of cyclo (his-pro) (CHP), alone or with zinc, to a subject. The composition contains an effective amount of cyclo (his-pro) (CHP) as an active ingredient. The composition may further contain zinc and/or other antidiabetic agent, or can be administered in combination with zinc and/or other antidiabetic agent.
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