公开(公告)号：US5292977A

公开(公告)日：1994-03-08

申请号：US49607

申请日：1993-04-20

Applicant: Barry M. Trost ,  Jacques Dumas

Inventor： Barry M. Trost ,  Jacques Dumas

IPC: B01J31/18 ,  B01J31/24 ,  C07B37/04 ,  C07B37/10 ,  C07B61/00 ,  C07C2/86 ,  C07C13/465 ,  C07C17/26 ,  C07C17/272 ,  C07C22/00 ,  C07C23/18 ,  C07C29/44 ,  C07C33/44 ,  C07C35/21 ,  C07C41/30 ,  C07C43/178 ,  C07C401/00 ,  C07F7/18 ,  C07C13/36 ,  C07C13/38 ,  C07C403/00

CPC classification number: C07F7/1892 ,  C07B37/10 ,  C07C17/2635 ,  C07C22/00 ,  C07C33/44 ,  C07C35/21 ,  C07C401/00 ,  Y02P20/55

Abstract: An alkylative cycloaddition method is provided that is particularly useful for the synthesis of many of the Vitamin D analogues with differing side chains. Thus, a preferred synthesis is of Vitamin D analogues having a side chain R.sub.1 where a substantially geometrically pure first precursor having the structure ##STR1## and a second precursor are provided, the second precursor being a 1,7 enyne. These precursors are reacted in the presence of a palladium catalyst to form compounds having the structure ##STR2## where R.sub.2 hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group, and R.sub.3 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group.

Abstract translation: 提供了对于合成具有不同侧链的许多维生素D类似物特别有用的烷基环加成方法。 因此，优选的合成是具有侧链R1的维生素D类似物，其中提供具有结构（*化学结构*）和第二前体的基本上几何纯的第一前体，第二前体是1,7烯。 这些前体在钯催化剂的存在下反应形成具有结构（*化学结构*）的化合物，其中R2氢，羟基，低级烷氧基，氟或保护基，R3是氢，羟基，低级烷氧基，氟 ，或保护基团。

公开(公告)号：US20170362583A1

公开(公告)日：2017-12-21

申请号：US15534681

申请日：2015-12-03

Applicant: DSM IP ASSETS B.V.

Inventor： John ROYER

IPC: C12N9/88 ,  C07C13/38 ,  C12N15/52 ,  C12N15/81 ,  C12N15/70 ,  C07C2602/18

Abstract: The present disclosure relates to a novel method, expression vectors, and host cells for producing abienol by converting geranylgeranyl diphosphate (GGPP) to abienol in the presence of a combination of a class II diterpene synthase and a bifunctional class I/II abienol synthase.

公开(公告)号：US5324875A

公开(公告)日：1994-06-28

申请号：US911447

申请日：1992-07-10

Applicant: Charles Fehr ,  Jose Galindo

Inventor： Charles Fehr ,  Jose Galindo

IPC: A61K8/33 ,  A61K8/35 ,  A61Q13/00 ,  C07C13/48 ,  C07C45/00 ,  C07C45/28 ,  C07C45/29 ,  C07C45/30 ,  C07C45/46 ,  C07C45/51 ,  C07C45/61 ,  C07C45/67 ,  C07C45/69 ,  C07C47/546 ,  C07C49/792 ,  C11B9/00 ,  C11D3/50 ,  C11D9/44 ,  D06M23/00 ,  D06M23/02 ,  C07C13/38 ,  C07C13/547

CPC classification number: C11B9/0053 ,  C07C13/48 ,  C07C45/004 ,  C07C45/28 ,  C07C45/305 ,  C07C45/513 ,  C07C45/673 ,  C07C45/676 ,  C07C45/69 ,  C07C47/546 ,  C07C49/792 ,  C07C2102/10 ,  C07C2103/16

Abstract: Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R.sup.1 and R.sup.2 are identical and represent each a hydrogen atom, or are different and represent each a hydrogen atom or a methyl radical, symbols R.sup.5 and R.sup.8 stand each for a methyl radical, symbols R.sup.6 and R.sup.7 can be identical or different and designate each a hydrogen atom or a methyl radical and, either symbol R.sup.4 represents a methyl radical and symbol R.sup.3 stands for a hydrogen atom or a methyl radical, or symbols R.sup.3 and R.sup.4 represent each a methylene radical belonging to a ring such as indicated by the dotted line, with the proviso that the following combinations are excluded:1. R.sup.1 =R.sup.2 =R.sup.3 =R.sup.6 =R.sup.7 =H, or2. R.sup.1 =R.sup.2 =R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or3. R.sup.2 =CH.sub.3 and R.sup.3 =R.sup.6 =R.sup.7 =H, or4. R.sup.2 =CH.sub.3 and R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or5. R.sup.1 =R.sup.3 =CH.sub.3, or6. R.sup.3 =R.sup.4 =CH.sub.2 and R.sup.2 or R.sup.7 =CH.sub.3 ; or whereinb) indexes m and n are different and define each an integer number equal to 0 or 1, symbol R.sup.2 stands for a hydrogen atom or a methyl radical, symbols R.sup.1 and R.sup.3 designate each a hydrogen atom, symbol R.sup.4 represents a methyl radical and, either symbols R.sup.5 and R.sup.6 are identical (n=1) and represent each a methylene radical belonging to a ring such as indicated by the dotted line, R.sup.7 representing a hydrogen atom and R.sup.8 a methyl radical, or symbol R.sup.5 stands for a methyl radical and symbol R.sup.6 for a hydrogen atom, R.sup.7 and R.sup.8 being then identical (m=1) and designating each a methylene radical belonging to a ring such as indicated by the dotted line;or any mixture of two or more structural isomers of formula (I).Compounds (I) develop odor notes of the musky type and can therefore be used as active ingredients in perfuming compositions and perfumed articles of varied nature.A process for the preparation of compounds (I) is described.

公开(公告)号：US09234054B2

公开(公告)日：2016-01-12

申请号：US14366690

申请日：2012-12-13

Applicant: Saudi Basic Industries Corporation

Inventor： Abdulaziz Hamad Al-Humydi ,  Atieh Aburaqabah ,  Christian Gorl ,  Helmut Alt

IPC: C07C13/36 ,  C07C13/38 ,  C07C1/32 ,  C07F17/00 ,  C08F4/6592 ,  C08F10/02 ,  C08F210/16 ,  C08F4/76 ,  C07C13/32 ,  C07C2/66 ,  C08F110/02

CPC classification number: C08F4/76 ,  C07C1/321 ,  C07C2/66 ,  C07C13/32 ,  C07C13/36 ,  C07C13/38 ,  C07F17/00 ,  C08F4/65927 ,  C08F110/02 ,  C08F4/65912

Abstract: A process comprising reacting a 2-indenylboranic acid (ester) with a bromosubstituted compound in the presence of the Pd catalyst bis(triphenylphosphin)palladium dichloride and a base to form the corresponding bridged bis(indenyl) ligand. Where the 2-indenylboranic acid (ester) is the pinacolester of 2-indenylboranic acid, the process may further comprise reacting a 2-bromo indene compound with pinacolborane in the presence of a Pd catalyst and a base to form the corresponding 2-indenylpinacolylborane compound. Bridged bis(indenyl)ligands may suitably be used in the preparation of metallocene complexes, such as 2,2′-bis(2-indenyl)biphenyl ZrCl2 and 1,2-bis (2-indenyl)benzene ZrCl2. These metallocene complexes may be used for the polymerization, optionally in the presence of a cocatalyst, of one or more α-olefins, preferably for the polymerization of ethylene.

Abstract translation: 一种方法包括在Pd催化剂双（三苯基膦）二氯化钯和碱的存在下使2-茚基硼烷酸（酯）与溴取代的化合物反应，形成相应的桥连双（茚基）配体。 当2-茚基硼烷酸（酯）是2-茚基硼烷酸的频哪醇酯时，该方法还可以包括在Pd催化剂和碱的存在下使2-溴茚化合物与频哪醇硼烷反应，形成相应的2-茚基茚基苯基硼烷化合物 。 桥连的双（茚基）配体可适当地用于制备茂金属络合物，例如2,2'-双（2-茚基）联苯基ZrCl 2和1,2-双（2-茚基）苯ZrCl 2。 这些金属茂络合物可以用于聚合，任选地在助催化剂存在下一种或多种α-烯烃，优选用于乙烯的聚合。

公开(公告)号：US5753578A

公开(公告)日：1998-05-19

申请号：US667622

申请日：1996-06-21

Applicant: Roberto Santi ,  Giampiero Borsotti ,  Antonio Proto ,  Liliana Gila ,  Karel Bujadoux

Inventor： Roberto Santi ,  Giampiero Borsotti ,  Antonio Proto ,  Liliana Gila ,  Karel Bujadoux

IPC: C07C13/38 ,  C07C1/32 ,  C07F17/00 ,  C08F4/60 ,  C08F4/64 ,  C08F4/642 ,  C08F4/659 ,  C08F4/6592 ,  C08F10/00

CPC classification number: C07C1/328 ,  C07F17/00 ,  C08F10/00 ,  C07C2101/10 ,  C07C2102/08 ,  C08F4/65908 ,  C08F4/65912 ,  C08F4/65927

Abstract: A catalyst active in the (co)polymerization of .alpha.-olefins is obtained by putting the following components in contact with each other: (i) a "bridged" bis-metallocene derivative of a metal M selected from titanium, zirconium or hafnium, wherein the divalent "bridge" has a rigid structure linked to two .eta..sup.5 -cyclopentadienyl ring with two methylene groups having a distance from each other of less than 3.5 .ANG.;(ii) a co-catalyst consisting of an organic derivative of a metal M' selected from boron, aluminium, gallium and tin. Such a catalyst allows high polymerization rates to be reached and is particularly suitable for high temperature polymerization process and co-polymerization of ethylene with other .alpha.-olefins.

Abstract translation: 通过使以下组分彼此接触获得在α-烯烃的（共）聚合中有活性的催化剂：（i）选自钛，锆或铪的金属M的“桥连”双茂金属衍生物，其中 二价“桥”具有与两个具有小于3.5的距离的两个亚甲基的两个η5-环戊二烯基连接的刚性结构; （ii）由选自硼，铝，镓和锡的金属M'的有机衍生物组成的助催化剂。 这种催化剂允许达到高聚合速率，并且特别适合于高温聚合方法和乙烯与其它α-烯烃的共聚。

公开(公告)号：US4570024A

公开(公告)日：1986-02-11

申请号：US731388

申请日：1985-05-07

Applicant: Kinya Mizui ,  Masami Takeda ,  Yoshimi Ozaki ,  Ryosuke Tomita

Inventor： Kinya Mizui ,  Masami Takeda ,  Yoshimi Ozaki ,  Ryosuke Tomita

IPC: C07C2/66 ,  C07C13/61 ,  C07C13/68 ,  C07C13/38

CPC classification number: C07C13/68 ,  C07C13/61 ,  C07C2/66 ,  C07C2103/68 ,  C07C2103/86

Abstract: An aromatic hydrocarbon in which at least one hydrogen atom on the ring is substituted by a group selected from the class consisting of unsubstituted or lower alkyl-substituted tricyclo[5.2.1.0.sup.2,6 ]dec-3-yl, tricyclo[5.2.1.0.sup.2,6 ]dec-4-yl, tetracyclo[6.2.1.1.sup.3,6.0.sup.2,7 ]dodec-4-yl and tetracyclo[6.2.1.1.sup.3,6.0.sup.2,7 ]dodec-5-yl groups, or its hydrogenation product.The compound is prepared by reacting an aromatic hydrocarbon having at least one hydrogen atom on the ring with a compound selected from the group consisting of unsubstituted or lower alkyl-substituted tricyclo[5.2.1.0.sup.2,6 ]dec-3-ene and tetracyclo[6.2.1.1.sup.3,6.0.sup.2,7 ]dodec-4-ene in the presence of a Friedel-Crafts catalyst, or hydrogenating the thus-obtained compound in the presence of a hydrogenation catalyst.The compound is useful as an additive for adhesives.

Abstract translation: 芳环，其中环上的至少一个氢原子被选自未取代或低级烷基取代的三环[5.2.1.02,6]癸-3-基，三环[5.2.1.02， 6]癸-4-基，四环[6.2.1.13,6.02,7]十二-4-基和四环[6.2.1.13,6.02,7]十二烷基-5-基，或其氢化产物。 该化合物通过在环上具有至少一个氢原子的芳族烃与选自未取代或低级烷基取代的三环[5.2.1.02,6]癸-3-烯和四环[6.2 .1.13,6.02,7]十二碳-4-烯在Friedel-Crafts催化剂存在下，或在氢化催化剂存在下氢化由此得到的化合物。 该化合物可用作粘合剂的添加剂。

公开(公告)号：US3965204A

公开(公告)日：1976-06-22

申请号：US468949

申请日：1974-05-10

Applicant: Joachim H. Lukas ,  Frank Baardman ,  Adriaan P. Kouwenhoven

Inventor： Joachim H. Lukas ,  Frank Baardman ,  Adriaan P. Kouwenhoven

IPC: B01J27/00 ,  C07B61/00 ,  C07C1/00 ,  C07C2/42 ,  C07C13/06 ,  C07C13/32 ,  C07C13/38 ,  C07C13/44 ,  C07C67/00 ,  C07C3/03

CPC classification number: C07C13/44 ,  C07C13/06 ,  C07C13/38 ,  C07C2/42 ,  C07C2101/04 ,  C07C2102/18 ,  C07C2102/50 ,  C07C2531/14

Abstract: Preparation of alkylidenecyclobutane derivatives and of cyclobutene derivatives by contacting a (cyclo)alkene with an allene or with a 1-alkyne in the liquid phase in the presence of a dissolved Lewis acid derived from an element of Group III A of the Periodic Table of the Elements, titanium, tin, antimony, tantalum, rhenium, iron, or zinc.

Abstract translation: 通过使（环）烯与丙烯或与1-炔炔在液相中，在衍生自元素周期表第IIIA族元素的溶解路易斯酸的存在下，制备亚烷基环丁烷衍生物和环丁烯衍生物 元素，钛，锡，锑，钽，铼，铁或锌。

公开(公告)号：US09630980B2

公开(公告)日：2017-04-25

申请号：US14876328

申请日：2015-10-06

Applicant: BOREALIS AG

Inventor： Norbert Hafner ,  Pascal Castro ,  Pavel Sergeevich Kulyabin ,  Vyatcheslav Izmer ,  Alexander Voskoboynikov ,  Luigi Resconi ,  Dmitry Kononovich ,  Ville Virkkunen ,  Dmitry Uborsky

IPC: C07C13/36 ,  C07C13/38 ,  C07C41/01 ,  C08F4/6592 ,  C07F7/08 ,  C07C13/465 ,  C07F17/00 ,  C08L23/12 ,  C08F10/06 ,  C08F110/06 ,  C08F210/06 ,  C08F4/659

CPC classification number: C07F7/081 ,  C07C13/36 ,  C07C13/38 ,  C07C13/465 ,  C07C41/01 ,  C07F17/00 ,  C08F4/65912 ,  C08F4/65916 ,  C08F4/65927 ,  C08F10/06 ,  C08F110/06 ,  C08F210/06 ,  C08L23/12 ,  C08L2207/02 ,  C08L2314/06 ,  C08L23/16 ,  C08F2500/03 ,  C08F2500/12 ,  C08F210/16

Abstract: A ligand of formula (I′) wherein L is a divalent bridge selected from —R′2C—, —R′2C—CR′2—, —R′2Si—, —R′2Si—SiR′2—, —R′2Ge—, wherein each R′ is independently a hydrogen atom, C1-20-hydrocarbyl, tri(C1-20-alkyl)silyl, C6-20-aryl, C7-20-arylalkyl or C7-20-alkylaryl; R2 and R2′ are each independently a C1-20 hydrocarbyl radical; R5′ is a C1-20 hydrocarbyl group; R6, R6′, R7 and R7′ are each independently hydrogen or a C1-20 hydrocarbyl group; Ar and Ar′ are independently an aryl or heteroaryl group having up to 20 carbon atoms; each R1 is a C1-20 hydrocarbyl group or two R1 groups on adjacent carbon atoms taken together can form a fused 5 or 6 membered non aromatic ring with the Ar group; and each R4 is a C1-20 hydrocarbyl group; and the dotted lines represent a double bond present in between carbons 1 and 2 or 2 and 3 of the indenyl ring.

公开(公告)号：US09522857B2

公开(公告)日：2016-12-20

申请号：US14118190

申请日：2012-05-18

Applicant: Yasushi Yamamoto ,  Hikaru Yatabe

Inventor： Yasushi Yamamoto ,  Hikaru Yatabe

IPC: C07C13/38 ,  C07C15/14 ,  C07C2/76 ,  B01J23/44 ,  B01J23/46 ,  B01J29/08 ,  C07C13/28 ,  C07D407/04 ,  C07C2/74 ,  C07C5/367

CPC classification number: C07C2/76 ,  B01J23/44 ,  B01J23/462 ,  B01J29/088 ,  C07C2/74 ,  C07C5/367 ,  C07C13/28 ,  C07C2521/04 ,  C07C2521/08 ,  C07C2521/12 ,  C07C2521/16 ,  C07C2521/18 ,  C07C2523/44 ,  C07C2523/63 ,  C07C2529/08 ,  C07C2529/18 ,  C07C2529/40 ,  C07C2529/50 ,  C07C2529/70 ,  C07C2601/14 ,  C07D407/04 ,  Y02P20/52 ,  C07C15/14

Abstract: A 3,3′,4,4′-tetraalkyl cyclohexylbenzene represented by the general formula (1): in which R represents an alkyl group having 1 to 4 carbon atoms, which may be easily converted into a 3,3′,4,4′-biphenyltetracarboxylic acid and a 3,3′,4,4′-biphenyltetracarboxylic dianhydride thereof, which are starting materials for a polyimide, via a 3,3′,4,4′-tetraalkylbiphenyl; and a method for producing the same.

公开(公告)号：US08329841B2

公开(公告)日：2012-12-11

申请号：US13327022

申请日：2011-12-15

Applicant: Dai-Seung Choi ,  Hye-Young Jung ,  Sung-Ho Chun ,  Heon Kim ,  Sung-Don Hong ,  Dong-Woo Yoo

Inventor： Dai-Seung Choi ,  Hye-Young Jung ,  Sung-Ho Chun ,  Heon Kim ,  Sung-Don Hong ,  Dong-Woo Yoo

IPC: C08F36/02 ,  C08F36/14 ,  C08F236/02 ,  C08F236/14 ,  C07C13/36 ,  C07C13/38

CPC classification number: C08F290/00 ,  C08F210/02 ,  C08F290/14 ,  C08F297/00 ,  C08F297/06 ,  C08F232/00 ,  C08F2500/25 ,  C08F2500/26

Abstract: The present invention relates to a photoreactive polymer that comprises a multi-cyclic compound in a main chain, and a polymerization method thereof. Since the photoreactive polymer according to the present invention comprises a multi-cyclic compound having a high glass transition temperature as a main chain, the thermal stability is excellent, and since the mobility of the main chain is relatively high as compared to that of an additional polymer, a photoreactive group can be freely moved in the main chain of the polymer. Accordingly, it is possible to overcome a slow photoreactive rate that is considered a disadvantage of a polymer material used to prepare an alignment film for known liquid crystal display devices.

Abstract translation: 本发明涉及在主链中包含多环化合物的光反应性聚合物及其聚合方法。 由于根据本发明的光反应性聚合物包含具有高玻璃化转变温度作为主链的多环化合物，因此热稳定性优异，并且由于主链的迁移率与附加的相比高， 聚合物，光反应性基团可以在聚合物的主链中自由移动。 因此，可以克服被认为是用于制备用于已知液晶显示装置的取向膜的聚合物材料的缺点的缓慢的光反应速率。