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    METHOD FOR AGROBACTERIUM-MEDIATED TRANSFORMATION OF PLANTS
    1.
    发明申请
    METHOD FOR AGROBACTERIUM-MEDIATED TRANSFORMATION OF PLANTS 失效
    农杆菌介导转化植物的方法

    公开(公告)号：US20090271896A1

    公开(公告)日：2009-10-29

    申请号：US11835237

    申请日：2007-08-07

    申请人： Ajith Anand ,  Kirankumar Mysore

    发明人： Ajith Anand ,  Kirankumar Mysore

    IPC分类号： A01H5/00 ,  C12N5/10 ,  C12N15/82 ,  C12N15/87 ,  C12N15/74

    CPC分类号： C12N15/8205 ,  C12N2770/00023

    摘要： The invention provides methods and compositions for enhancing the efficiency of Agrobacterium-mediated transformation of host cells such as plant cells. Plant expression constructs comprising a gene encoding a VIP2 or VIP2-like polypeptide are provided, as well as methods for utilizing such constructs to enhance Agrobacterium-mediated transformation efficiency.

    摘要翻译： 本发明提供用于提高农杆菌介导的宿主细胞如植物细胞转化效率的方法和组合物。 提供了包含编码VIP2或VIP2样多肽的基因的植物表达构建体，以及利用这些构建体来提高农杆菌介导的转化效率的方法。

    BIONANOMATERIALS AND THEIR SYNTHESIS
    2.
    发明申请
    BIONANOMATERIALS AND THEIR SYNTHESIS 有权
    生物分子及其合成

    公开(公告)号：US20090029441A1

    公开(公告)日：2009-01-29

    申请号：US12090579

    申请日：2006-11-01

    申请人： Qian Wang ,  Zhongwel Niu

    发明人： Qian Wang ,  Zhongwel Niu

    IPC分类号： C12N7/00

    CPC分类号： C12N7/00 ,  B82Y5/00 ,  C12N2770/00023 ,  D01F1/10 ,  D01F6/76 ,  Y10S977/762

    摘要： The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to form composite nanofibers that are fixed together in a head-to-tail assembly by a polymer. Also, 2-dimensional nanostructures formed from crosslinked viruses assembled in a single, film-like layer are generally disclosed. Porous gels having controllable pore size through the use of virus particles are also disclosed.

    摘要翻译： 通常公开了使用诸如病毒和病毒样颗粒的生物材料来形成纳米结构。 例如，棒状病毒可以用于形成复合纳米纤维，它们通过聚合物以头对尾组装方式固定在一起。 此外，通常公开了由组装在单个膜状层中的交联病毒形成的二维纳米结构。 还公开了通过使用病毒颗粒具有可控孔径的多孔凝胶。

    Bionanomaterials and their synthesis
    6.
    发明授权
    Bionanomaterials and their synthesis 有权
    Bionan材料及其合成

    公开(公告)号：US08334127B2

    公开(公告)日：2012-12-18

    申请号：US12883295

    申请日：2010-09-16

    申请人： Qian Wang ,  Zhongwei Niu

    发明人： Qian Wang ,  Zhongwei Niu

    IPC分类号： C12N7/00

    CPC分类号： C12N7/00 ,  B82Y5/00 ,  C12N2770/00023 ,  D01F1/10 ,  D01F6/76 ,  Y10S977/762

    摘要： The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to form composite nanofibers that are fixed together in a head-to-tail assembly by a polymer. Also, 2-dimensional nanostructures formed from crosslinked viruses assembled in a single, film-like layer are generally disclosed. Porous gels having controllable pore size through the use of virus particles are also disclosed.

    摘要翻译： 通常公开了使用诸如病毒和病毒样颗粒的生物材料来形成纳米结构。 例如，棒状病毒可以用于形成复合纳米纤维，它们通过聚合物以头对尾组装方式固定在一起。 此外，通常公开了由组装在单个膜状层中的交联病毒形成的二维纳米结构。 还公开了通过使用病毒颗粒具有可控孔径的多孔凝胶。

    Method for agrobacterium-mediated transformation of plants
    7.
    发明授权
    Method for agrobacterium-mediated transformation of plants 失效
    农杆菌介导的植物转化方法

    公开(公告)号：US08053638B2

    公开(公告)日：2011-11-08

    申请号：US11835237

    申请日：2007-08-07

    申请人： Ajith Anand ,  Kirankumar Mysore

    发明人： Ajith Anand ,  Kirankumar Mysore

    IPC分类号： C12N15/84 ,  C12N5/04 ,  C12N5/10 ,  A01H5/00 ,  A01H5/10

    CPC分类号： C12N15/8205 ,  C12N2770/00023

    摘要： The invention provides methods and compositions for enhancing the efficiency of Agrobacterium-mediated transformation of host cells such as plant cells. Plant expression constructs comprising a gene encoding a VIP2 or VIP2-like polypeptide are provided, as well as methods for utilizing such constructs to enhance Agrobacterium-mediated transformation efficiency.

    摘要翻译： 本发明提供用于提高农杆菌介导的宿主细胞如植物细胞转化效率的方法和组合物。 提供了包含编码VIP2或VIP2样多肽的基因的植物表达构建体，以及利用这些构建体来提高农杆菌介导的转化效率的方法。

    Bionanomaterials and Their Synthesis
    8.
    发明申请
    Bionanomaterials and Their Synthesis 有权
    Bionan材料及其合成

    公开(公告)号：US20110151542A1

    公开(公告)日：2011-06-23

    申请号：US12883295

    申请日：2010-09-16

    申请人： Qian Wang ,  Zhongwei Niu

    发明人： Qian Wang ,  Zhongwei Niu

    IPC分类号： C12N7/00

    CPC分类号： C12N7/00 ,  B82Y5/00 ,  C12N2770/00023 ,  D01F1/10 ,  D01F6/76 ,  Y10S977/762

    摘要： The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to form composite nanofibers that are fixed together in a head-to-tail assembly by a polymer. Also, 2-dimensional nanostructures formed from crosslinked viruses assembled in a single, film-like layer are generally disclosed. Porous gels having controllable pore size through the use of virus particles are also disclosed.

    摘要翻译： 通常公开了使用诸如病毒和病毒样颗粒的生物材料来形成纳米结构。 例如，棒状病毒可以用于形成复合纳米纤维，它们通过聚合物以头对尾组装方式固定在一起。 此外，通常公开了由组装在单个膜状层中的交联病毒形成的二维纳米结构。 还公开了通过使用病毒颗粒具有可控孔径的多孔凝胶。

    Flexible vaccine assembly and vaccine delivery platform
    9.
    发明申请
    Flexible vaccine assembly and vaccine delivery platform 审中-公开
    灵活的疫苗组装和疫苗交付平台

    公开(公告)号：US20050282263A1

    公开(公告)日：2005-12-22

    申请号：US11090497

    申请日：2005-03-25

    申请人： Alison McCormick ,  Mark Smith ,  Kenneth Palmer ,  John Lindbo ,  Long Nguyen ,  Gregory Pogue

    发明人： Alison McCormick ,  Mark Smith ,  Kenneth Palmer ,  John Lindbo ,  Long Nguyen ,  Gregory Pogue

    IPC分类号： C12N7/00 ,  C12N7/04 ,  C12N15/86

    CPC分类号： C12N7/00 ,  A61K2039/5258 ,  C12N2710/20022 ,  C12N2770/00023

    摘要： Herein described are various methods for making a vaccine that are made of re-assembled virus like particles (VLP). First, the VLPs are disassembled into coat proteins or encapsidation intermediate populations. Each population undergoes, for instance, chemical conjugation of unique peptide or nucleic moieties to form separate populations. Thereafter, a predetermined amount of each of the several (one or more) different coat proteins or encapsidation intermediates from the different populations is mixed and joined, forming intact VLPs, surrounding a nucleic acid core, that are composed of different coat proteins such that the reassembled VLP displays more than one peptide or other molecule. The nucleic acid can function either as a scaffold alone or can be engineered for the expression of an immunomodulatory protein in a eukaryotic cell.

    摘要翻译： 本文描述了制备由重新组装的病毒样颗粒（VLP）制成的疫苗的各种方法。 首先，将VLP分解成外壳蛋白或衣壳化中间种群。 每个群体经历例如独特的肽或核酸部分的化学共轭以形成分开的群体。 此后，将来自不同群体的几种（一种或多种）不同外壳蛋白或壳化中间体中的每一种的预定量混合并连接，形成围绕核酸核心的完整VLP，其由不同的外壳蛋白组成，使得 重组VLP显示多于一个肽或其他分子。 核酸可以作为单独的支架起作用，或者可以被工程化以在真核细胞中表达免疫调节蛋白。