Functionalized rubbery polymers
    8.
    发明授权
    Functionalized rubbery polymers 有权
    官能化橡胶聚合物

    公开(公告)号:US09587060B2

    公开(公告)日:2017-03-07

    申请号:US11603719

    申请日:2006-11-22

    摘要: This invention discloses a process for the synthesis of a rubbery polymer by emulsion polymerization that comprised polymerizing (1) a conjugated diolefin monomer and (2) a functionalized monomer having the structural formula: wherein the R1 groups can be the same or different and represent hydrogen atoms or alkyl groups containing from 1 to about 8 carbon atoms, wherein R2 represents a hydrogen atom or an alkyl group containing from 1 to about 8 carbon atoms, wherein R3 represents a hydrogen atom or an alkyl group containing from 1 to about 8 carbon atoms, and wherein R4 represents a hydrogen atom or an alkyl group containing from 1 to about 8 carbon atoms, with the proviso that if R3 represent an alkyl group then R4 represents a hydrogen atom, and with the proviso that R4 represents an alkyl group then R3 represents a hydrogen atom, wherein said polymerization is conducted in an aqueous medium, and wherein said polymerization is initiated with a free radical initiator.

    摘要翻译: 本发明公开了一种功能单体,其用于聚合物,橡胶组合物,轮胎以及制备这种橡胶组合物的方法。 所述官能单体具有选自由以下组成的组的结构式:其中R 1基可以相同或不同,表示氢原子或含有1至8个碳原子的烷基,其中R 2表示氢原子或烷基 含有1至8个碳原子的基团,其中R 3表示氢原子或含有1至8个碳原子的烷基,其中R 4表示氢原子或含有1至8个碳原子的烷基,条件是 如果R 3表示烷基,则R 4表示氢原子,条件是R 4表示烷基,则R 3表示氢原子,并且其中R 5可以相同或不同,表示烷基 含有1至8个碳原子的基团。

    Antifouling heparin coatings
    9.
    发明授权
    Antifouling heparin coatings 有权
    防污肝素涂层

    公开(公告)号:US09561309B2

    公开(公告)日:2017-02-07

    申请号:US10857141

    申请日:2004-05-27

    摘要: A medical device comprising a coating thereon comprising a biocompatible polymer and heparin is provided herein. Heparin is coupled with the biocompatible polymer via a spacer having a grouping that renders a binding site of the heparin molecule accessible by a binding protein. The medical device can be implanted in a human being for the treatment of a disease such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

    摘要翻译: 本文提供了包括其上的包含生物相容性聚合物和肝素的医疗装置。 肝素通过具有使得肝素分子的结合位点可被结合蛋白使得的分组的间隔物与生物相容性聚合物偶联。 医疗器械可以植入人类用于治疗动脉粥样硬化,血栓形成,再狭窄,出血,血管解剖或穿孔,血管动脉瘤,易损斑块,慢性完全闭塞,跛行,静脉和人造移植物的吻合增殖等疾病 ,胆管阻塞,输尿管阻塞,肿瘤阻塞或其组合。