公开(公告)号：US20240061331A1

公开(公告)日：2024-02-22

申请号：US18485674

申请日：2023-10-12

申请人： FUJIFILM Corporation

发明人： Yosuke BEKKI ,  Masafumi KOJIMA ,  Akiyoshi GOTO ,  Nishiki FUJIMAKI

IPC分类号： G03F7/004 ,  C07C25/02 ,  C07C309/42 ,  C07C381/12 ,  C07D307/00 ,  C07D307/12 ,  C07D307/33 ,  C07D309/12 ,  C07D327/06 ,  C07D333/46 ,  C07D333/76 ,  C07D493/18 ,  C08F220/18 ,  C08F220/28 ,  C08F220/38 ,  G03F7/038 ,  G03F7/039

CPC分类号： G03F7/0045 ,  C07C25/02 ,  C07C309/42 ,  C07C381/12 ,  C07D307/00 ,  C07D307/12 ,  C07D307/33 ,  C07D309/12 ,  C07D327/06 ,  C07D333/46 ,  C07D333/76 ,  C07D493/18 ,  C08F220/1806 ,  C08F220/1807 ,  C08F220/1809 ,  C08F220/281 ,  C08F220/382 ,  G03F7/038 ,  G03F7/039 ,  C07C2601/14 ,  C07C2602/42 ,  C07C2603/74

摘要： An actinic ray-sensitive or radiation-sensitive resin composition contains a compound represented by general formula (S1) and an acid decomposable resin. In the general formula (S1), Q1, Q2, Q3, Q4, and Q5 each independently represent a hydrogen atom or a substituent, provided that at least one of Q1, Q2, Q3, Q4, or Q5 represents a substituent including an aryloxy group represented by general formula (QR1), Lq1 represents a single bond or a divalent linking group; and M+ represents an organic cation. In the general formula (QR1), G1, G2, G3, G4, and G5 each independently represent a hydrogen atom or a substituent, provided that at least one of G1, G2, G3, G4, or G5 represents a substituent including an ester group; and * represents a bonding position.

公开(公告)号：US20190142833A1

公开(公告)日：2019-05-16

申请号：US16189113

申请日：2018-11-13

申请人： Merck Patent GmbH

发明人： Thomas Fuchss ,  Ulrich Emde ,  Hans-Peter Buchstaller ,  Werner Mederski

IPC分类号： A61K31/519 ,  C07D285/01 ,  C07D405/14 ,  C07D239/72 ,  C07D237/14 ,  C07C25/02 ,  C07D513/04 ,  C07D473/00 ,  A61K31/5377 ,  A61K31/5386 ,  A61K45/06 ,  C07D239/74 ,  C07D403/14 ,  C07D498/08 ,  C07D495/04 ,  C07D491/048 ,  C07D487/04 ,  C07D471/04 ,  C07D417/14 ,  C07D417/10 ,  C07D405/04 ,  C07D403/10 ,  C07D401/10 ,  C07D265/30

CPC分类号： A61K31/519 ,  A61K31/5377 ,  A61K31/5386 ,  A61K45/06 ,  C07C25/02 ,  C07D237/14 ,  C07D239/72 ,  C07D239/74 ,  C07D265/30 ,  C07D285/01 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D417/10 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/08 ,  C07D513/04

摘要： The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.

公开(公告)号：US10045969B2

公开(公告)日：2018-08-14

申请号：US15097002

申请日：2016-04-12

申请人： NISSAN CHEMICAL INDUSTRIES, LTD.

发明人： Takeshi Mita ,  Takamasa Kikuchi ,  Takashi Mizukoshi ,  Manabu Yaosaka ,  Mitsuaki Komoda ,  Shinji Takii

IPC分类号： A61K31/421 ,  A61K9/00 ,  C07C25/13 ,  C07C25/24 ,  C07C25/02 ,  C07C25/06 ,  C07C25/08 ,  A01N43/80 ,  C07C43/174 ,  C07C205/11 ,  C07C205/12 ,  C07C211/52 ,  C07C251/48 ,  C07C255/29 ,  C07C255/50 ,  C07C255/60 ,  C07C281/02 ,  C07C323/09 ,  C07D261/16 ,  C07D413/04 ,  C07D413/06 ,  C07D413/12 ,  C07D417/06 ,  C07D417/12 ,  C07F7/08 ,  C07D261/04 ,  C07D413/14

CPC分类号： A61K31/421 ,  A01N43/80 ,  A61K9/0053 ,  C07C25/02 ,  C07C25/06 ,  C07C25/08 ,  C07C25/13 ,  C07C25/24 ,  C07C43/1742 ,  C07C43/1745 ,  C07C205/11 ,  C07C205/12 ,  C07C211/52 ,  C07C251/48 ,  C07C255/29 ,  C07C255/50 ,  C07C255/60 ,  C07C281/02 ,  C07C323/09 ,  C07D261/04 ,  C07D261/16 ,  C07D413/04 ,  C07D413/06 ,  C07D413/12 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07F7/0812

摘要： A substituted alkenylbenzene compound of formula (4): wherein X1 is selected from the group consisting of halogen atom, —SF5, C1-C6halo alkyl, hydroxy C1-C6haloalkyl, C1-C6alkoxy C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6 haloalkoxy, C1-C3haloalkoxy C1-C3haloalkoxy, C1-C6haloalkylthio, C1-C6haloalkylsulfinyl and C1-C6haloalkylsulfonyl; X3 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy and C1-C6 alkylthio; X4 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, C1-C4alkyl, C1-C4alkoxy and C1-C4haloalkoxy; R3 is —C(R3a)(R3b)R3c, where R3a and R3b independently of each other are a halogen atom, or R3a and R3b together form 3- to 6-membered ring together with the carbon atom bonding them by forming a C2-C5haloalkylene chain, and R3c is selected from the group consisting of a hydrogen atom, halogen atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy and C1-C4haloalkylthio, with a proviso that in case where X1 is a fluorine atom, chlorine atom or trifluoromethyl, and both X2 and X3 are a hydrogen atom, in case where both X1 and X2 are fluorine atom and X3 is a hydrogen atom, and in case where both X1 and X2 are trifluoromethyl and X3 is a hydrogen atom, R3c is a hydrogen atom, chlorine atom, bromine atom, iodine atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy or C1-C4haloalkylthio.

公开(公告)号：US20170290836A1

公开(公告)日：2017-10-12

申请号：US15633064

申请日：2017-06-26

申请人： Merck Patent GmbH

发明人： Thomas Fuchss ,  Ulrich Emde ,  Hans-Peter Buchstaller ,  Werner Mederski

IPC分类号： A61K31/519 ,  C07C25/02 ,  C07D265/30 ,  C07D237/14 ,  C07D239/72 ,  C07D285/01

CPC分类号： A61K31/519 ,  A61K31/5377 ,  A61K31/5386 ,  A61K45/06 ,  C07C25/02 ,  C07D237/14 ,  C07D239/72 ,  C07D239/74 ,  C07D265/30 ,  C07D285/01 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D417/10 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/08 ,  C07D513/04

摘要： The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.

公开(公告)号：US09741934B2

公开(公告)日：2017-08-22

申请号：US15127847

申请日：2014-11-21

申请人： Sumitomo Chemical Company, Limited

发明人： Tomoyasu Yoshida ,  Mio Shiratori

IPC分类号： C08G75/00 ,  H01L51/00 ,  C07F15/00 ,  C07F5/00 ,  C07F5/02 ,  C08G61/12 ,  C07C13/567 ,  C07C22/04 ,  C07C25/02 ,  C07C31/20 ,  C07C33/30 ,  C07C35/38 ,  C09K11/02 ,  C09K11/06 ,  C08G61/10 ,  C08L65/00 ,  H01L51/50

CPC分类号： H01L51/0035 ,  C07C13/567 ,  C07C22/04 ,  C07C25/02 ,  C07C31/20 ,  C07C33/30 ,  C07C35/38 ,  C07C2602/06 ,  C07C2603/18 ,  C07F5/003 ,  C07F5/025 ,  C07F15/0033 ,  C08G61/10 ,  C08G61/12 ,  C08G61/122 ,  C08G61/126 ,  C08G61/128 ,  C08G2261/124 ,  C08G2261/135 ,  C08G2261/312 ,  C08G2261/3142 ,  C08G2261/3162 ,  C08G2261/411 ,  C08G2261/512 ,  C08G2261/514 ,  C08G2261/76 ,  C08G2261/95 ,  C08L65/00 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1059 ,  C09K2211/185 ,  H01L51/0039 ,  H01L51/0043 ,  H01L51/5016 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092

摘要： A polymer compound comprising a constitutional unit having a group represented by the formula (1): wherein Ring A1A and Ring R2A represent an aromatic hydrocarbon ring or a heterocyclic ring and these rings each optionally have a substituent, nA represents an integer of 0 to 5, nB represents an integer of 1 to 5, LA and LB represent an alkylene group, a cycloalkylene group, an arylene group, a divalent heterocyclic ring group, a group represented by —NR′—, an oxygen atom or a sulfur atom, and R′ represents a hydrogen atom, an alkyl group or the like, and Q1 represents a crosslinkable group.

公开(公告)号：US09732094B2

公开(公告)日：2017-08-15

申请号：US14890214

申请日：2014-05-08

申请人： Merck Patent GmbH

发明人： Thomas Fuchss ,  Ulrich Emde ,  Hans-Peter Buchstaller ,  Werner Mederski

IPC分类号： C07D513/04 ,  C07D239/74 ,  C07D401/10 ,  C07D403/10 ,  C07D405/04 ,  C07D405/14 ,  C07D417/10 ,  C07D417/14 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/08 ,  C07D471/04 ,  A61K31/5377 ,  A61K31/5386 ,  A61K45/06 ,  C07D403/14 ,  C07D473/00

CPC分类号： A61K31/519 ,  A61K31/5377 ,  A61K31/5386 ,  A61K45/06 ,  C07C25/02 ,  C07D237/14 ,  C07D239/72 ,  C07D239/74 ,  C07D265/30 ,  C07D285/01 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D417/10 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/08 ,  C07D513/04

摘要： The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitization of cancer cells to anticancer agents and/or ionizing radiation.

公开(公告)号：US20170189890A1

公开(公告)日：2017-07-06

申请号：US15316393

申请日：2015-06-08

申请人： Northwestern University ,  King Abdulaziz City for Science and Technology

发明人： James M. HOLCROFT ,  Karel J. HARTLIEB ,  James Fraser STODDART

IPC分类号： B01J20/22 ,  C07C17/389 ,  C07C7/12 ,  B01J20/28 ,  B01J20/30

CPC分类号： B01J20/226 ,  B01J20/28004 ,  B01J20/3021 ,  B01J20/305 ,  B01J20/3085 ,  C07C7/12 ,  C07C7/13 ,  C07C17/38 ,  C07C17/389 ,  C07C2601/16 ,  C07C2602/42 ,  Y02P20/582 ,  C07C15/04 ,  C07C15/06 ,  C07C15/073 ,  C07C15/08 ,  C07C15/085 ,  C07C15/02 ,  C07C15/46 ,  C07C13/20 ,  C07C13/23 ,  C07C13/21 ,  C07C13/42 ,  C07C25/06 ,  C07C25/13 ,  C07C25/02 ,  C07C22/08 ,  C07C25/08

摘要： A separation medium consisting of a cyclodextrin metal-organic framework (CD-MOF) for separating aromatic compounds and methods of preparing the same are presented. Bottom-up preparations include the following steps: (a) preparing a first mixture comprising a cyclodextrin, an alkali metal salt, water and an alcohol; (b) performing one of the following two steps: (i) stirring the first mixture; or (ii) adding an amount of a surfactant to the first mixture to form a second mixture; and (c) crystallizing the CD-MOF from the first mixture or the second mixture. Top-down preparations include the following steps: (a) preparing a first mixture comprising the cyclodextrin, an alkali metal salt, water and an alcohol; (b) crystallizing the CD-MOF from the first mixture; and (c) optionally performing particle size reduction of the crystallized CD-MOF. The CD-MOFs are amenable for use in methods for separating alkylaromatic and haloaromatic compounds from a mixture of hydrocarbons.

公开(公告)号：US09637462B2

公开(公告)日：2017-05-02

申请号：US15034751

申请日：2014-11-05

申请人： TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED

发明人： Gennady Nisnevich ,  Kseniya Kulbitski ,  Mark Gandelman ,  Alexander Artaryan

IPC分类号： C07D263/26 ,  C07D275/06 ,  C07D233/82 ,  C07C41/22 ,  C07D233/74 ,  C07D263/22 ,  C07D209/48 ,  C07C17/093 ,  C07C29/64 ,  C07C41/05 ,  C07C67/05 ,  C07C201/12 ,  C07D211/38 ,  C07C17/10 ,  C07C17/12 ,  C07C17/14 ,  C07C17/363 ,  C07B39/00 ,  C07D207/46

CPC分类号： C07D263/26 ,  C07B39/00 ,  C07C17/093 ,  C07C17/10 ,  C07C17/12 ,  C07C17/14 ,  C07C17/363 ,  C07C29/64 ,  C07C41/05 ,  C07C41/22 ,  C07C67/05 ,  C07C201/12 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2601/18 ,  C07C2602/42 ,  C07D207/46 ,  C07D209/48 ,  C07D211/38 ,  C07D233/74 ,  C07D233/82 ,  C07D263/22 ,  C07D275/06 ,  C07C43/225 ,  C07C35/48 ,  C07C43/192 ,  C07C33/46 ,  C07C43/174 ,  C07C69/63 ,  C07C22/04 ,  C07C25/02 ,  C07C205/12 ,  C07C25/13 ,  C07C205/11 ,  C07C23/10 ,  C07C23/28 ,  C07C23/08 ,  C07C23/14 ,  C07C23/16 ,  C07C19/07

摘要： The present invention provides new stable crystalline N-iodoamides-1-iodo-3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water.

公开(公告)号：US20170092864A1

公开(公告)日：2017-03-30

申请号：US15127847

申请日：2014-11-21

申请人： Sumitomo Chemical Company, Limited

发明人： Tomoyasu YOSHIDA ,  Mio SHIRATORI

IPC分类号： H01L51/00 ,  C07C13/567 ,  C07C33/30 ,  C07C31/20 ,  C09K11/06 ,  C07C25/02 ,  C07F5/02 ,  C08G61/12 ,  C09K11/02 ,  C07C35/38 ,  C07C22/04

CPC分类号： H01L51/0035 ,  C07C13/567 ,  C07C22/04 ,  C07C25/02 ,  C07C31/20 ,  C07C33/30 ,  C07C35/38 ,  C07C2602/06 ,  C07C2603/18 ,  C07F5/003 ,  C07F5/025 ,  C07F15/0033 ,  C08G61/10 ,  C08G61/12 ,  C08G61/122 ,  C08G61/126 ,  C08G61/128 ,  C08G2261/124 ,  C08G2261/135 ,  C08G2261/312 ,  C08G2261/3142 ,  C08G2261/3162 ,  C08G2261/411 ,  C08G2261/512 ,  C08G2261/514 ,  C08G2261/76 ,  C08G2261/95 ,  C08L65/00 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1059 ,  C09K2211/185 ,  H01L51/0039 ,  H01L51/0043 ,  H01L51/5016 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092

摘要： A polymer compound comprising a constitutional unit having a group represented by the formula (1): wherein Ring A1A and Ring R2A represent an aromatic hydrocarbon ring or a heterocyclic ring and these rings each optionally have a substituent, nA represents an integer of 0 to 5, nB represents an integer of 1 to 5, LA and LB represent an alkylene group, a cycloalkylene group, an arylene group, a divalent heterocyclic ring group, a group represented by —NR′—, an oxygen atom or a sulfur atom, and R′ represents a hydrogen atom, an alkyl group or the like, and Q1 represents a crosslinkable group.

公开(公告)号：US09440908B2

公开(公告)日：2016-09-13

申请号：US14396570

申请日：2013-04-25

申请人： BAYER CROPSCIENCE AG

发明人： Thomas Himmler ,  Sandra Lehmann ,  Thomas Norbert Muller ,  Mathias Riedrich ,  Lars Rodefeld ,  Frank Volz ,  Sascha Von Morgenstern

IPC分类号： C07C211/40 ,  C07C209/26 ,  C07C17/093 ,  C07C25/06 ,  C07C45/00 ,  C07C201/12 ,  C07C209/00 ,  C07C209/36 ,  C07C209/70 ,  C07C245/20 ,  C07C249/02 ,  C07F3/02

CPC分类号： C07C211/40 ,  C07C17/093 ,  C07C25/06 ,  C07C45/004 ,  C07C201/12 ,  C07C209/00 ,  C07C209/26 ,  C07C209/365 ,  C07C209/70 ,  C07C245/20 ,  C07C249/02 ,  C07C2601/02 ,  C07F3/02 ,  Y10S585/931 ,  C07C47/55 ,  C07C211/52 ,  C07C251/24 ,  C07C209/68 ,  C07C251/04 ,  C07C209/52 ,  C07C25/02 ,  C07C205/06

摘要： The present invention relates to a process for preparing N-(5-chloro-2-isopropylbenzyl)cyclopropanamine by hydrogenation of N-[(5-chloro-2-isopropylphenyl)methylene]cyclopropanamine over specific platinum catalysts.

摘要翻译： 本发明涉及通过在特定的铂催化剂上氢化N - [（5-氯-2-异丙基苯基）亚甲基]环丙胺而制备N-（5-氯-2-异丙基苄基）环丙胺的方法。