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    METHOD OF FILLING PHARMACEUTICAL CONTAINERS
    1.
    发明公开
    METHOD OF FILLING PHARMACEUTICAL CONTAINERS 审中-公开

    公开(公告)号：US20240199249A1

    公开(公告)日：2024-06-20

    申请号：US18553654

    申请日：2022-03-31

    Applicant: 3P Innovation Limited

    Inventor： Thomas BAILEY ,  Roderick MITCHELL

    IPC: B65B3/00 ,  B65B7/16 ,  B65B43/46 ,  B65B43/59 ,  B65B55/02

    CPC classification number: B65B3/003 ,  B65B7/161 ,  B65B43/46 ,  B65B43/59 ,  B65B55/027

    Abstract: There is described a method of aseptically filling a plurality of nested containers with a pharmaceutical product and applying closures to filled containers in an aseptic environment, said method comprising: removing any coverings from the nested containers and nested closures; locating the uncovered containers laterally adjacent to the closures on a shuttle; moving the uncovered containers and uncovered closures to an aseptic filling zone; transferring the uncovered containers and closures to a multi-nest holder; locating the uncovered containers laterally adjacent to a plurality of closures in the multi-nest holder; filling the containers with a pharmaceutical product; removing a closure from the nest of closures into a closure transfer device; moving the nest of filled containers beneath the closure transfer device; and removing a closure from the closure transfer device into the filled container thereby scaling the filled container.

    APPARATUS AND METHOD FOR FILLING AND RESEALING
    5.
    发明申请
    APPARATUS AND METHOD FOR FILLING AND RESEALING 审中-公开
    装置和方法用于填充和回收

    公开(公告)号：US20170036788A1

    公开(公告)日：2017-02-09

    申请号：US15333506

    申请日：2016-10-25

    Applicant: MEDINSTILL DEVELOPMENT LLC

    Inventor： Daniel Py ,  Benoit Adamo ,  John Guthy

    IPC: B65B7/16 ,  B65B37/06 ,  B65B43/54 ,  B65B55/08 ,  B65B57/00 ,  B65B65/02 ,  B65B3/00 ,  B65B51/22

    CPC classification number: B65B7/161 ,  B65B3/003 ,  B65B7/00 ,  B65B37/06 ,  B65B43/54 ,  B65B51/22 ,  B65B55/04 ,  B65B55/08 ,  B65B57/00 ,  B65B65/02

    Abstract: Apparatus for filling devices that are penetrable for filling the devices with a substance, and resealable for sealing the resulting hole. A device support supports at least one such device in a substantially fixed position relative to the support during filling and/or resealing. A manifold drivingly mounted over the device support can include (1) a cartridge including a filling needle for penetrating a resealable stopper and introducing a substance therethrough into the device, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold can include a thermal source for heating a penetrated region of the stopper and, sealing the hole.

    Abstract translation: 用于填充用于将材料填充到装置中的可渗透装置的装置，并且可重新密封用于密封所产生的孔。 装置支撑件在填充和/或再密封期间相对于支撑件支撑至少一个这样的装置，其基本上固定的位置。 驱动地安装在装置支撑件上的歧管可以包括（1）包括用于穿透可重新密封的止动件并将物质引入其中的填充针的药筒，用于将药筒安装在歧管上的支架和可释放地联接到 用于在从歧管运输，安装和/或移除药筒期间覆盖填充针的安装件。 歧管可以包括用于加热塞子的穿透区域并密封孔的热源。

    PROCEDURE FOR THE MANUFACTURE OF VIALS FOR FLUID PRODUCTS, PARTICULARLY FOR MEDICAL, PHARMACEUTICAL, COSMETIC, FOOD PRODUCTS OR THE LIKE
    6.
    发明申请
    PROCEDURE FOR THE MANUFACTURE OF VIALS FOR FLUID PRODUCTS, PARTICULARLY FOR MEDICAL, PHARMACEUTICAL, COSMETIC, FOOD PRODUCTS OR THE LIKE 审中-公开
    用于制造流体产品，特别用于医药，药物，化妆品，食品或类似物的方法

    公开(公告)号：US20160152359A1

    公开(公告)日：2016-06-02

    申请号：US14904099

    申请日：2014-07-07

    Applicant: LAMEPLAST S.P.A.

    Inventor： Antonio FONTANA

    IPC: B65B7/16 ,  B65B3/00 ,  B65B51/22 ,  A61J1/06

    CPC classification number: B65B7/161 ,  A61J1/067 ,  A61J2205/30 ,  B29C45/0081 ,  B29C45/261 ,  B65B3/003 ,  B65B51/142 ,  B65B51/225 ,  B65D1/095 ,  B65D2203/00 ,  B65D2203/02

    Abstract: The procedure for the manufacture of vials for fluid products, particularly for medical, pharmaceutical, cosmetic, food products or the like, comprises the steps of: forming at least a vial (1) having: at least a containment body (4) for at least a fluid product, the containment body (4) having a longitudinal direction (D), a first extremity (5) suitable for defining a dispensing mouth (6) of the fluid product and a second extremity (7) substantially tubular opposite the first extremity (5) and suitable for defining an introduction opening (8) of the fluid product having an edge (9); and at least a closing element (10) of the dispensing mouth (6); filling the containment body (4) with the fluid product with the dispensing mouth (6) closed by the closing element (10); sealing the introduction opening (8) by squeezing the edge (9) between at least two sealing elements (16) to define a sealed portion (17, 18) substantially plate-shaped; applying information, data or logos (21) on the sealed portion (17, 18).

    Abstract translation: 用于制造用于流体产品，特别是用于医疗，医药，化妆品，食品等的流体产品的小瓶的方法包括以下步骤：形成至少一个具有至少一个容纳体（4）的小瓶（1） 至少一个流体产品，所述容纳体（4）具有纵向方向（D），适于限定流体产品的分配口（6）的第一末端（5）和与所述流体产品相对的第二末端（7） 末端（5）并且适于限定具有边缘（9）的流体产品的引入开口（8）; 和至少一个分配口（6）的关闭元件（10）。 用所述流体产品填充所述容纳体（4），所述分配口（6）由所述封闭元件（10）封闭; 通过在至少两个密封元件（16）之间挤压所述边缘（9）来密封所述引入开口（8），以限定基本上板形的密封部分（17,18） 将信息，数据或标识（21）应用于密封部分（17,18）上。

    Apparatus and method for capping and sealing pharmaceutical vials
    7.
    发明授权
    Apparatus and method for capping and sealing pharmaceutical vials 有权
    用于封盖和密封药瓶的装置和方法

    公开(公告)号：US09096334B2

    公开(公告)日：2015-08-04

    申请号：US14316002

    申请日：2014-06-26

    Applicant: Genesis Packaging Technologies

    Inventor： F. William Bogle ,  Richard Spencer

    IPC: B65B7/28 ,  B65B7/16

    CPC classification number: B65B7/285 ,  B65B7/161 ,  B65B7/2821

    Abstract: An apparatus and a method for capping and sealing a vial with a cap assembly including a deformable annular seal, e.g., a ferrule, is disclosed. The apparatus comprises a base for holding the vial, a pressure applying platen, plural sealing rollers and associated electronic circuitry and motors. The platen is arranged to be moved relative to the base, whereupon it engages and applies a force to the cap assembly. The load cell measures the force applied and provides a signal indicative thereof to the electronic circuitry. The electronic circuitry determines when a desired amount of force has been applied to control the operation of the rollers, whereupon the rollers apply a force to the annular seal to permanently crimp the annular seal on the vial.

    Abstract translation: 公开了一种用包括可变形环形密封件（例如套圈）的盖组件来封盖和密封小瓶的装置和方法。 该装置包括用于保持小瓶的基座，压力施加台板，多个密封辊和相关联的电子电路和马达。 压板布置成相对于基座移动，于是其接合并向盖组件施加力。 称重传感器测量施加的力，并向电子电路提供指示其的信号。 电子电路确定何时施加了所需的力量以控制辊的操作，于是辊向环形密封件施加力以将环形密封件永久地卷曲在小瓶上。

    Sealed containers and methods of filling and resealing same
    9.
    发明授权
    Sealed containers and methods of filling and resealing same 有权
    密封容器和填充和重新密封方法

    公开(公告)号：US07992597B2

    公开(公告)日：2011-08-09

    申请号：US12791629

    申请日：2010-06-01

    Applicant: Daniel Py ,  Norbert M. Assion

    Inventor： Daniel Py ,  Norbert M. Assion

    IPC: B65B1/04

    CPC classification number: B65B3/003 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2096 ,  A61M2207/00 ,  A61M2209/045 ,  B65B3/027 ,  B65B7/161 ,  B65B51/10 ,  B65B55/08 ,  B65B2039/009 ,  B65D51/002

    Abstract: Disclosed is a container and method for filling same. The container includes a thermally resealable portion that is fusible in response to thermal energy, and a container body having a sealed empty chamber in fluid communication with the resealable portion for receiving therein a substance. The container also includes a base, a mid-portion, and an upper portion axially spaced from the base on an opposite side of the mid-portion relative to the base. Each of the base and upper portion define a laterally-extending dimension greater than a maximum laterally-extending dimension of the mid-portion. The method of filling the container includes penetrating the resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member while engaging the base of the body to substantially prevent axial movement of the body, and applying thermal energy to the resealable portion to thermally fuse the penetrated region thereof.

    Abstract translation: 公开了一种容器及其填充方法。 该容器包括能够响应于热能而易熔的可热再密封部分，以及具有密封空腔的容器主体，其与可再密封部分流体连通，用于在其中容纳物质。 容器还包括基部，中间部分和与基部相对于基部在中间部分的相对侧上轴向间隔开的上部。 基部和上部中的每一个限定大于中间部分的最大横向延伸尺寸的横向延伸的尺寸。 填充容器的方法包括用注射构件穿透可重新密封的部分并将物质引入腔室中，在与身体的基部接触的同时取出注射构件，以基本上防止身体的轴向移动，并将热能施加到可重新密封 部分，以热熔融其穿透区域。

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