公开(公告)号：US20240156684A1

公开(公告)日：2024-05-16

申请号：US18545356

申请日：2023-12-19

Applicant: Becton Dickinson and Company Limited

Inventor： Jude Cancellieri ,  Kivilcim Eralp ,  Paul Paia Marici ,  Derek Hugger ,  James J. Kennedy, III ,  Daniel Hamilton

IPC: A61J1/20 ,  B65B3/00 ,  B65B3/04 ,  B65B7/16 ,  B65B43/54 ,  B65B51/14 ,  B67B3/22 ,  B67B7/92

CPC classification number: A61J1/2006 ,  A61J1/2003 ,  A61J1/2048 ,  B65B3/003 ,  B65B3/04 ,  B65B7/161 ,  B65B43/54 ,  B65B51/142 ,  B67B3/22 ,  B67B7/92 ,  A61J1/10

Abstract: An assembly fixture device for attaching a vial adapter to a vial includes a base, a support member secured to the base, a handle connected to the support member, a vial adapter grip assembly connected to the handle and comprising an adapter grip member configured to engage and hold a vial adapter, and a vial grip assembly connected to the base comprising first and second grip members that are movable relative to each other and configured to engage and hold a vial. The first grip member is biased toward the second grip member to provide a vial engagement force, where the vial engagement force is about constant when a distance between the first and second grip members is less than 40 mm.

公开(公告)号：US20230399217A1

公开(公告)日：2023-12-14

申请号：US18032266

申请日：2021-10-13

Applicant: Verrica Pharmaceuticals Inc.

Inventor： Eugene R. Scavola ,  Paul Daly ,  Gregory Alcorn ,  Vicki Fluck

IPC: B67B7/92 ,  A61M35/00 ,  A61J1/06

CPC classification number: B67B7/92 ,  A61M35/003 ,  A61J1/065

Abstract: Tools (100) for crushing an ampule (146) contained within an applicator (102) for a therapeutic are disclosed herein. The ampule crush tool may be configured to rest on an incline relative to a flat surface. Further, the ampule crush tool may include a spill reservoir (122) for collecting a volume of the therapeutic expelled during an ampule crushing operation. Additionally, the ampule crush tool may form a fully enclosed cavity such that the ampule crush tool may contain the therapeutic even when the therapeutic is expelled from the ampule along an unpredictable trajectory. The ampule crush tool may also be shaped to orient an ampule-containing applicator in a suitable orientation within the ampule crush tool.

公开(公告)号：US20150368083A1

公开(公告)日：2015-12-24

申请号：US14313779

申请日：2014-06-24

Applicant: Coup Brands IP, LLC

Inventor： Ryan Tu ,  Tark Abed ,  Feng Hao Yu ,  Peter Privitera ,  Lawson Fisher ,  Natasha Gangjee ,  Ryan Braunstein

IPC: B67B7/92

CPC classification number: B67B7/92 ,  Y10T225/10 ,  Y10T225/371

Abstract: A rack for bottle sabering includes an elongated body defining an open compartment dimensioned to accommodate a pressurized bottle of fluid. The body partially encloses the bottle, leaving at least an underside of a neck and rim on one side of the bottle exposed for a sabering strike to sever the top of the bottle.

Abstract translation: 用于瓶子的机架包括限定敞开室的细长主体，其尺​​寸适于容纳加压瓶的流体。 身体部分地包围瓶子，至少留下瓶颈的一侧的颈部和边缘的下侧，暴露于瓶颈，以切断瓶子的顶部。

公开(公告)号：US09131930B2

公开(公告)日：2015-09-15

申请号：US13318892

申请日：2009-12-17

Applicant: Andy Greter

Inventor： Andy Greter

IPC: B65B1/04 ,  A61B17/00 ,  A61J1/06 ,  B67B7/92 ,  A61M5/178 ,  A61J1/20 ,  A61B19/00 ,  A61M5/19

CPC classification number: A61B17/00491 ,  A61B2017/00495 ,  A61B2090/037 ,  A61J1/065 ,  A61J1/20 ,  A61J1/201 ,  A61J1/2086 ,  A61J1/2096 ,  A61M5/1782 ,  A61M5/19 ,  B67B7/92

Abstract: A filling device (300) for breaking at least one ampoule (700) and for filling a syringe (600) from the ampoule is disclosed. The filling device has a base body (310), which delimits at least one hollow space (315). At the distal end, each hollow space has a removal opening, which is connected to a port (313) for the multi-use syringe. A breaking unit is designed to break the ampoule located in the hollow space. In some embodiments, the breaking unit comprises an actuating element, which is used to slide at least two ampoules onto a wedge-shaped structure, respectively, by way of a single actuating movement in the longitudinal direction, in order to apply a lateral force on the tips of the ampoules. In other embodiments, the breaking unit comprises an actuating element (320) that can be inserted in the transverse direction and acts directly on the tips of the ampoules in order to shatter or shear them off.

Abstract translation: 公开了一种用于打破至少一个安瓿（700）并用于从安瓿填充注射器（600）的填充装置（300）。 填充装置具有限定至少一个中空空间（315）的基体（310）。 在远端，每个中空空间具有一个移除开口，该开口连接到用于多用途注射器的端口（313）。 破碎装置设计用于打破位于中空空间的安瓿。 在一些实施例中，断裂单元包括致动元件，该致动元件用于通过在纵向方向上的单一致动运动将至少两个安瓿分别滑动到楔形结构上，以便施加横向力 安瓿的尖端。 在其他实施例中，断裂单元包括致动元件（320），该致动元件可以在横向上插入并且直接作用在安瓿的尖端上，以便使其破碎或剪切。

公开(公告)号：US08973800B2

公开(公告)日：2015-03-10

申请号：US13799833

申请日：2013-03-13

Applicant: Fu-Chao Liu ,  San-I Huang ,  Po-Yao Huang ,  Hung-Ni Huang

Inventor： Fu-Chao Liu ,  San-I Huang ,  Po-Yao Huang ,  Hung-Ni Huang

IPC: B67B7/92 ,  B67B7/44

CPC classification number: B67B7/92 ,  B67B7/44 ,  Y10T83/403 ,  Y10T83/412 ,  Y10T225/30 ,  Y10T225/371 ,  Y10T225/386

Abstract: An ampoule opener has an opening unit and a cover unit. The opening unit is a rigid frame and has two panels, two head-clamping holes and two pairs of wave-shaped flanges. The panels are respectively an upper panel and a lower panel. The head-clamping holes are elongated in length and tapered in width and are respectively formed through the panels. The pairs of wave-shaped flanges are formed between the panels and the head-clamping holes. The cover unit is flexible, is detachably mounted around the opening unit and has two covering boards, a mounting recess, two body-clamping holes and two pairs of wave-shaped edges. The body-clamping holes are elongated in length and tapered in width and are respectively formed through the mounting boards and communicate with the mounting recess. The pairs of wave-shaped edges are formed between the mounting boards and the body-clamping holes.

Abstract translation: 安瓿开启器具有开启单元和盖单元。 开口单元是刚性框架，具有两个面板，两个头夹紧孔和两对波形法兰。 面板分别是上面板和下面板。 头夹紧孔的长度是细长的，并且在宽度上呈锥形，分别通过面板形成。 一对波形凸缘形成在面板和头夹紧孔之间。 盖单元是柔性的，可拆卸地安装在开口单元周围，并具有两个覆盖板，安装凹槽，两个主体夹紧孔和两对波形边缘。 主体夹紧孔的长度是细长的，并且在宽度上呈锥形，分别形成在安装板上并与安装凹槽连通。 成对的波形边缘形成在安装板和主体夹紧孔之间。

公开(公告)号：US08915413B2

公开(公告)日：2014-12-23

申请号：US13639694

申请日：2011-03-10

Applicant: Ralph Egon Kayser

Inventor： Ralph Egon Kayser

IPC: B67B7/92

CPC classification number: B67B7/92 ,  Y10T225/30 ,  Y10T225/329 ,  Y10T225/371

Abstract: A device for opening an ampoule (3) comprises a hollow cylindrical housing (11) having an interior for accommodating the ampoule (3) and a rotary element (12) having a proximal section (121), to which a break-off section (124) extending in a distal direction is connected to. The break-off section (124) is flexible in a radial direction and is pivotably connected to the proximal section (121) in the radial direction. The rotary element (12) is rotatable relative to the housing (11) about the longitudinal axis. The housing (11) has a first guiding structure (119) for pressing the break-off section (124) inward during a rotation of the rotary element so that the break-off section (124) exerts a radial shear force on an ampoule head (33) of an ampoule (3) to break the ampoule head (33) off of the ampoule body (31).

Abstract translation: 用于打开安瓿（3）的装置包括具有用于容纳安瓿（3）的内部的中空圆柱形壳体（11）和具有近侧部分（121）的旋转元件（12），分离部分 124）在远端方向上延伸。 断开部分（124）在径向上是柔性的，并且在径向方向上可枢转地连接到近侧部分（121）。 旋转元件（12）可围绕纵向轴线相对于壳体（11）旋转。 壳体（11）具有用于在旋转元件的旋转期间向内挤压分离部分（124）的第一引导结构（119），使得分离部分（124）在安瓿头上施加径向剪切力 （3）的安装孔（33），以将安瓿头（33）从安瓿主体（31）上拆下。

公开(公告)号：US08840001B2

公开(公告)日：2014-09-23

申请号：US13203054

申请日：2010-02-27

Applicant: Cezary Pluska

Inventor： Cezary Pluska

IPC: B26F3/02 ,  B67B7/92

CPC classification number: B67B7/92 ,  Y10T225/30 ,  Y10T225/325 ,  Y10T225/371

Abstract: An apparatus for breaking off the head of a glass ampoule that is composed of a cylindrical body, a neck forming a predetermined breaking point and a head, comprising an incline extending in an inclined manner to the axis of the ampoule to be inserted toward the same, a first support surface is disposed on the side of the incline causing a break-off of the head in the region above the bottom of the ampoule to be inserted at a radius of the ampoule from the axis of the apparatus and a second support surface is disposed on the opposite side beneath the neck of the ampoule at a distance from the axis of the apparatus that corresponds to the radius of the ampoule, during a relative movement of the apparatus to the ampoule in the direction of the axis thereof the incline breaks off the head at the neck.

Abstract translation: 一种用于分离玻璃安瓿头部的装置，其由圆柱体，形成预定断裂点的颈部和头部组成，包括倾斜方向延伸到安瓿的轴线以向其插入的倾斜装置 第一支撑表面设置在倾斜面上，导致头部在安瓿底部之上的区域中断，以便从该装置的轴线插入安瓿的半径处，并且第二支撑表面 在装置的轴线方向上相对于安瓿的半径一定距离处设置在安瓿瓶颈下方的相对侧，在该装置相对于安瓿在其轴线方向上相对移动时，倾斜断裂 在脖子上的头部。

公开(公告)号：US07490723B2

公开(公告)日：2009-02-17

申请号：US10876323

申请日：2004-06-23

Applicant: Ricardo Levisman

Inventor： Ricardo Levisman

IPC: A61J1/06 ,  B67B7/92

CPC classification number: B65D77/0493 ,  A61C8/0087 ,  A61J1/065 ,  Y10T225/30

Abstract: A glass ampoule for packaging and containing solid matter under sterile conditions, the glass ampoule comprising an integral glass body having a breaking section, the breaking section being breakable to define an opening large enough to easily remove the matter.

Abstract translation: 一种用于在无菌条件下包装和含有固体物质的玻璃安瓿，所述玻璃安瓿包括具有断裂部分的整体玻璃体，所述断裂部分是可断裂的，以限定足够大的开口以容易地除去该物质。

公开(公告)号：US06874187B2

公开(公告)日：2005-04-05

申请号：US10288030

申请日：2002-11-05

Applicant: Christopher M. Tague ,  Kris D. Eager

Inventor： Christopher M. Tague ,  Kris D. Eager

IPC: B67B7/92 ,  B67B7/00

CPC classification number: B67B7/92 ,  Y10T225/30

Abstract: An opener and tool for breaking medical containers, such as, for example, ampoules that includes an elongated handle which has a first end and a second end, an upper edge and a lower edge, and an opener which defines an opening extending into the upper edge at the first end and further defining a flexible cantilevered arm. The opener and tool has at least one arcuate pocket for gripping containers of different sizes between sides of the opening, holding the container and breaking a tip of the container to remove a liquid therefrom for further use with powdered components to produce a mix. The opener and tool also includes a spatula disposed at the second end of the handle.

Abstract translation: 用于破坏医疗容器的开启器和工具，例如包括具有第一端和第二端的细长手柄的安瓿，上边缘和下边缘，以及开口器，其限定延伸到上部的开口 在第一端处边缘并进一步限定柔性悬臂。 开启器和工具具有至少一个弓形凹槽，用于在开口的侧面之间夹持不同尺寸的容器，保持容器并破坏容器的尖端以从其中除去液体以进一步与粉末组件一起使用以产生混合物。 开启器和工具还包括设置在手柄的第二端的刮刀。

公开(公告)号：US5658474A

公开(公告)日：1997-08-19

申请号：US358230

申请日：1994-12-16

Applicant: Johan H. Geerke

Inventor： Johan H. Geerke

IPC: B67B7/92 ,  A61K9/00 ,  B23K26/00 ,  B23K26/02 ,  B23K26/08 ,  B23K26/38

CPC classification number: B23K26/082 ,  A61K9/0004 ,  B23K26/0838 ,  B23K26/382 ,  B23K26/386 ,  B23K26/402 ,  B23K2203/42

Abstract: A method of laser drilling a delivery port (37) in a beneficial agent dispenser (30) is disclosed. A dispenser (30) has a compartment (32) formed by a wall (31) for containing a beneficial agent (33) to be delivered. A laser beam is employed for burning at least partially through the wall (31). The laser beam and the dispenser (30) are positioned relative to one another such that the laser beam is aimed at a predetermined port site (35) on the dispenser (30). The laser beam is turned off (unenergized) during the positioning period. The laser beam is then energized and moved relative to the dispenser (30) for scribing a delivery port (37) proximate the port site (35). The scribing motion moves the laser beam from the port site (35) along a course (37). Preferably the course (37) is closed. The scribing motion causes the burning of the wall (31) by the laser beam to scribe the delivery port (37). The positioning motion and the scribing motion are controlled by a scanning system (16). The laser source (13) beam is energized during the scribing motion for burning the wall (31) forming the delivery port (37) therein for subsequent delivery of the beneficial agent (33) therethrough.

Abstract translation: 公开了一种在有益剂分配器（30）中激光钻孔输送口（37）的方法。 分配器（30）具有由壁（31）形成的用于容纳要输送的有益剂（33）的隔室（32）。 使用激光束至少部分地通过壁（31）进行燃烧。 激光束和分配器（30）相对于彼此定位，使得激光束瞄准分配器（30）上的预定端口位置（35）。 激光束在定位期间关闭（未通电）。 激光束然后被激励并相对于分配器（30）移动，用于在靠近端口位置（35）处划出输送端口（37）。 划线运动沿着路线（37）将激光束从端口位置（35）移动。 优选地，过程（37）是关闭的。 划线运动导致激光束对壁（31）的燃烧以划分输送口（37）。 定位运动和划线运动由扫描系统（16）控制。 激光源（13）光束在划线运动期间通电，用于燃烧形成输送口（37）的壁（31），用于随后将有益剂（33）输送通过其中。