公开(公告)号：US20240181163A1

公开(公告)日：2024-06-06

申请号：US18493446

申请日：2023-10-24

申请人： Merit Medical Systems, Inc.

发明人： Michael Dean Haslam ,  Nicole Willardson ,  Richard P. Jenkins

IPC分类号： A61M5/31 ,  A61M5/315

CPC分类号： A61M5/3129 ,  A61M5/31505 ,  A61M2005/3131 ,  A61M2005/31506 ,  A61M2205/0222 ,  A61M2207/00

摘要： Syringe systems including barrels having lubricated portions and non-lubricated portions are provided. The non-lubricated portions may be configured to be loaded with injectable materials, such as embolic agents. The injectable materials may comprise polyvinyl alcohol. Also provided are plungers having plunger tips and seal members. Also provided are methods of lubricating portions of barrels of syringe systems with lubricants including silicone or silicone-free lubricants.

公开(公告)号：US11911341B2

公开(公告)日：2024-02-27

申请号：US16077640

申请日：2017-02-15

申请人： MITSUBISHI GAS CHEMICAL COMPANY, INC.

发明人： Shota Arakawa ,  Toshiya Naito ,  Satoshi Okada ,  Kenichiro Usuda ,  Takumi Toida ,  Haruka Okazaki ,  Fumihiro Ito

IPC分类号： A61J1/14 ,  A61J1/05 ,  B65D1/09 ,  B32B27/32 ,  B32B27/08 ,  B32B27/34 ,  B32B1/02 ,  B65D1/00 ,  C08G69/32 ,  A61J1/06 ,  B32B27/18 ,  A61M5/31 ,  B29C49/00 ,  B29C49/06 ,  C08G69/06 ,  C08G69/26 ,  B29K77/00 ,  B29L31/00

CPC分类号： A61J1/1468 ,  A61J1/05 ,  A61J1/06 ,  A61M5/3129 ,  B29C49/0005 ,  B29C49/06 ,  B32B1/02 ,  B32B27/08 ,  B32B27/18 ,  B32B27/32 ,  B32B27/325 ,  B32B27/34 ,  B65D1/00 ,  B65D1/09 ,  C08G69/06 ,  C08G69/26 ,  C08G69/32 ,  A61M2005/3131 ,  A61M2207/00 ,  B29C2949/3032 ,  B29C2949/3034 ,  B29K2077/00 ,  B29L2031/712 ,  B32B2250/02 ,  B32B2250/03 ,  B32B2250/05 ,  B32B2250/24 ,  B32B2250/40 ,  B32B2307/30 ,  B32B2307/412 ,  B32B2307/7244 ,  B32B2439/80 ,  B32B2535/00 ,  C08G2390/00

摘要： Provided is a multilayer vessel excellent in gas barrier performance and transparency and its application. The multilayer vessel contains a layer (X) that contains at least one type of polyolefin resin as the major ingredient; and a layer (Y) that contains a polyamide resin (A) as the major ingredient, the polyamide resin (A) being composed of a structural unit derived from diamine, and a structural unit derived from dicarboxylic acid, 70 mol % or more of the structural unit derived from diamine being derived from metaxylylenediamine, meanwhile 30 to 60 mol % of the structural unit derived from dicarboxylic acid being derived from straight chain aliphatic α,ω-dicarboxylic acid having 4 to 20 carbon atoms, and 70 to 40 mol % being derived from isophthalic acid.

公开(公告)号：US20240001036A1

公开(公告)日：2024-01-04

申请号：US18038080

申请日：2021-11-19

申请人： W. L. Gore & Associates, Inc.

发明人： Tyler N. Hinkle ,  Robert C. Basham ,  David T. Morse

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/31513 ,  A61M5/3129 ,  A61M2005/3131

摘要： Methods and associated structures for translating a syringe stopper though a lubricant free tube, such as an insertion tube, syringe barrel or cartridge tube, during the assembly and/or use of the syringe or auto-injector. The stopper in a non-compressed state includes a proximal end, a plunger rod engaging cavity, and a sealing region having a length spaced from the proximal end by a sealing location length. The sealing region includes at least one rib having at least one microgroove within a polymer barrier, the at least one microgroove having an initial width. By the disclosed methods and structures, a translation force biased towards the outer diameter of the stopper is applied to the stopper using force concentrators. The translation force with force concentrators is sufficient to translate the stopper though the tube in a compressed state with a reduction of increase in the initial width of the at least one microgroove when compared to not using force concentrators.

公开(公告)号：US11707577B2

公开(公告)日：2023-07-25

申请号：US16093121

申请日：2017-04-07

申请人： Santen Pharmaceutical Co., Ltd. ,  Congruence Medical Solutions, LLC

发明人： Gautam N. Shetty ,  Lou Castagna

IPC分类号： A61M5/00 ,  A61M35/00 ,  A61M5/315 ,  A61F9/00 ,  A61M5/31 ,  A61M5/34 ,  A61M37/00 ,  A61M39/10

CPC分类号： A61M5/31551 ,  A61F9/0008 ,  A61M5/3129 ,  A61M5/31558 ,  A61M5/31575 ,  A61M5/31585 ,  A61M5/34 ,  A61M37/0015 ,  A61M39/10 ,  A61M2005/3131

摘要： According to some embodiments, a syringe may include a barrel; a delivery conduit; a plunger seal disposed within the barrel; and a plunger rod assembly affixed to an end of the barrel, the plunger rod assembly including a first plunger rod component comprising a first linear gear, a second plunger rod component disposed at least partially in the barrel and engaged with the plunger seal, wherein the second plunger rod component comprises a second linear gear, a first rotational gear having a plurality of gear teeth for engaging the first linear gear, and a second rotational gear having a second plurality of gear teeth for engaging the second linear gear, wherein the first rotational gear is coupled to the second rotational gear such that translation of the first plunger rod component causes translation of the second plunger rod component.

公开(公告)号：US11701471B2

公开(公告)日：2023-07-18

申请号：US16564928

申请日：2019-09-09

申请人： SCHOTT Pharma AG & Co. KGaA

发明人： Stephanie Mangold ,  Tamara Sweeck

IPC分类号： A61M5/31 ,  C10M107/50 ,  C10N40/00 ,  C10N50/08

CPC分类号： A61M5/3134 ,  C10M107/50 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238 ,  A61M2207/00 ,  C10M2227/045 ,  C10M2229/025 ,  C10N2040/50 ,  C10N2050/08

摘要： A liquid preparation for application to an inner side of a hollow body to produce a sliding layer on a packaging for pharmaceuticals or cosmetic products comprises the following constituents: a reactive silicone system for forming a silicone network of the sliding layer, a catalyst for catalyzing the cross-linking reaction of the reactive silicone system, at least one unreactive silicone oil, and at least one diluent. The diluent comprises a silicon-containing compound and a content of the at least one diluent in the preparation amounts to more than 45 percent by weight and less than 95 percent by weight in the preparation.

公开(公告)号：US11697132B2

公开(公告)日：2023-07-11

申请号：US16854498

申请日：2020-04-21

申请人： Schott AG

发明人： Matthias Bicker ,  Manfred Lohmeyer ,  Hartmut Bauch

IPC分类号： B05D3/14 ,  C03C17/28 ,  H01J37/32 ,  B05D1/00 ,  B05D7/22 ,  C03C17/00 ,  A61M5/31

CPC分类号： B05D3/147 ,  A61M5/3129 ,  B05D1/62 ,  B05D7/22 ,  C03C17/004 ,  C03C17/28 ,  H01J37/32394 ,  A61M2005/3131 ,  B05D2201/00 ,  B05D2203/35 ,  B05D2259/00

摘要： An apparatus and to a method for treating layers using a plasma zone sealed from the outer atmospheric pressure are provided. The apparatus and method include a plasma reactor including a substrate carrier in form of a container receiving means, and a closing element that is joined with the substrate carrier by means of a lifting device.

公开(公告)号：US20230201464A1

公开(公告)日：2023-06-29

申请号：US18115131

申请日：2023-02-28

申请人： SCHOTT Pharma AG & Co. KGaA

发明人： Elmar Horsch ,  Tanja Woywod

IPC分类号： A61M5/31 ,  A61J1/06

CPC分类号： A61M5/3129 ,  A61J1/062 ,  A61M2005/3131 ,  A61M2205/0238

摘要： A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper, the stopper having a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition, the stopper having a circumferential surface partially contacting an inner surface of the barrel, a surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness, the inner surface of the barrel having a surface roughness Ra of less than 100 nm.

公开(公告)号：US11684546B2

公开(公告)日：2023-06-27

申请号：US17717854

申请日：2022-04-11

申请人： SiO2 Medical Products, Inc.

发明人： Christopher Weikart ,  Becky L. Clark ,  Adam Stevenson ,  John T. Felts

IPC分类号： A61J1/14 ,  A61J1/00 ,  C23C16/02 ,  C23C16/04 ,  C23C16/40 ,  C23C16/455 ,  G01N27/22 ,  G01N33/53 ,  G01N33/543 ,  G01N33/74 ,  A61J1/03 ,  A61J1/05 ,  A61L31/04 ,  A61L31/08 ,  A61L31/14 ,  C23C16/50 ,  A61L31/16 ,  A61M5/31 ,  B65D25/14

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/035 ,  A61J1/05 ,  A61L31/04 ,  A61L31/08 ,  A61L31/088 ,  A61L31/143 ,  A61L31/16 ,  A61M5/3129 ,  B65D25/14 ,  C23C16/029 ,  C23C16/045 ,  C23C16/401 ,  C23C16/45523 ,  C23C16/50 ,  G01N27/227 ,  G01N33/5308 ,  G01N33/5438 ,  G01N33/74 ,  A61L2420/02 ,  A61L2420/08 ,  A61M2005/3131 ,  A61M2205/0238 ,  G01N2333/62 ,  G01N2800/042

摘要： An article or vessel is described including a vessel surface and a coating set comprising at least one tie coating, at least one barrier coating, and at least one pH protective coating. For example, the coating set can comprise a tie coating, a barrier coating, a pH protective coating and a second barrier coating; and in the presence of a fluid composition, the fluid contacting surface is the barrier coating or layer. The respective coatings can be applied by PECVD of a polysiloxane precursor. Such vessels can have a coated interior portion containing a fluid with a pH of 4 to 8. The barrier coating prevents oxygen from penetrating into the thermoplastic vessel, and the tie coating and pH protective coating together protect the barrier layer from the contents of the vessel. The second barrier coating is comparable to glass surface if needed.

公开(公告)号：US20190070364A1

公开(公告)日：2019-03-07

申请号：US15834333

申请日：2017-12-07

申请人： URO-1, Inc.

发明人： Phillip Jack Snoke ,  Philip Morrison Allred, III ,  John Joseph Smith

IPC分类号： A61M5/31 ,  A61B1/307 ,  A61M5/315

CPC分类号： A61M5/3137 ,  A61B1/00135 ,  A61B1/307 ,  A61M5/3156 ,  A61M5/31595 ,  A61M2005/3131 ,  A61M2205/3379 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2210/1085

摘要： An incremental syringe is provided and includes a syringe barrel, a finger grip disposed at the proximal end of the syringe barrel, a tab disposed inside the syringe barrel, and a plunger body having detentes, wherein the detentes are configured to interact with the tab to provide audible and tactile feedback to a user when the plunger body is pushed through the syringe barrel in a distal direction.

公开(公告)号：US20190038828A1

公开(公告)日：2019-02-07

申请号：US16053227

申请日：2018-08-02

申请人： Insulet Corporation

发明人： Ian MCLAUGHLIN

IPC分类号： A61M5/00 ,  A61L2/20 ,  A61M5/31

CPC分类号： A61M5/001 ,  A61L2/0094 ,  A61L2/206 ,  A61L2202/182 ,  A61L2202/21 ,  A61L2202/23 ,  A61L2202/24 ,  A61M5/002 ,  A61M5/14248 ,  A61M5/3129 ,  A61M2005/3114 ,  A61M2005/312 ,  A61M2005/3128 ,  A61M2005/3131 ,  A61M2209/045

摘要： A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed.