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    Methods and apparatus for an analyte detecting device
    1.
    发明申请
    Methods and apparatus for an analyte detecting device 审中-公开
    分析物检测装置的方法和装置

    公开(公告)号：US20070123802A1

    公开(公告)日：2007-05-31

    申请号：US11534977

    申请日：2006-09-25

    Applicant: Dominique Freeman

    Inventor： Dominique Freeman

    IPC: A61B5/00 ,  B65B55/00 ,  B27N3/08

    CPC classification number: A61B5/15176 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15159 ,  A61B5/15161

    Abstract: In one embodiment according to the present invention, a device is provided comprising a cartridge having a plurality of cavities. The device may include a plurality of penetrating members at least partially contained in the cavities of the single cartridge wherein the penetrating members are slidably movable to extend outward from lateral openings on the cartridge to penetrate tissue. The device may have a sterility barrier coupled to the cartridge, wherein the sterility barrier covers a plurality of the lateral openings, and wherein the sterility barrier covering the lateral openings is configured to be moved so that a penetrating member exits the lateral opening without contacting the barrier. The device may include a plurality of analyte detecting members coupled to the cartridge and a plurality of sample capture devices, wherein the sample capture devices each having an opening there through to allow a penetrating member to pass through.

    Abstract translation: 在根据本发明的一个实施例中，提供了包括具有多个空腔的盒的装置。 该装置可以包括至少部分地容纳在单个盒的空腔中的多个穿透构件，其中穿透构件可滑动地移动以从盒上的侧向开口向外延伸以穿透组织。 该装置可以具有耦合到盒的无菌屏障，其中无菌屏障覆盖多个侧向开口，并且其中覆盖侧向开口的无菌屏障构造成移动，使得穿透构件离开侧向开口而不接触 屏障。 该装置可以包括耦合到盒的多个分析物检测构件和多个样品捕获装置，其中每个样品捕获装置在其上具有开口以允许穿透构件通过。

    Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
    2.
    发明申请
    Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein 审中-公开
    用于提取体液和监测其中的分析物的装置，系统和方法

    公开(公告)号：US20040249254A1

    公开(公告)日：2004-12-09

    申请号：US10861749

    申请日：2004-06-04

    Inventor： Joel Racchini ,  Phil Stout ,  Michael Edward Hilgers ,  Thomas Rademacher ,  Joel Mechelke ,  Cass A. Hanson

    IPC: A61B005/05

    CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/022 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15087 ,  A61B5/15117 ,  A61B5/15159 ,  A61B5/157 ,  A61B5/6824 ,  A61B2560/0431 ,  A61B2562/0295

    Abstract: A system for extracting a bodily fluid sample (e.g., an interstitial fluid nullISFnull sample) and monitoring an analyte therein includes a disposable cartridge and a local controller module. The disposable cartridge includes a sampling module adapted to extract a bodily fluid sample and an analysis module adapted to measure an analyte (e.g., glucose) in the bodily fluid sample. The local controller module is in electronic communication with the disposable cartridge and is adapted to receive and store measurement data from the analysis module. An ISF extraction device includes a penetration member configured for penetrating and residing in a target site of a user's skin layer and, subsequently, extracting an ISF sample therefrom. The device also includes a pressure ring(s) adapted for applying pressure to the user's skin layer in the vicinity of the target site. The device is configured such that the pressure ring(s) is capable of applying pressure in an oscillating manner whereby an ISF glucose lag of the ISF sample extracted by the penetration member is mitigated. A method for extracting ISF includes providing an ISF fluid extraction device with a penetration member and a pressure ring(s). Next, a user's skin layer is contacted by the pressure ring(s) and penetrated by the penetration member. An ISF sample is then extracted from the user's skin layer while pressure is being applied in an oscillating manner by the pressure ring(s). The oscillating pressure mitigates an ISF glucose lag of the extracted ISF sample.

    Abstract translation: 用于提取体液样品（例如，间质液体[ISF]样品）和监测其中的分析物的系统包括一次性盒和本地控制器模块。 一次性药筒包括适于提取体液样品的采样模块和适于测量体液样品中分析物（例如葡萄糖）的分析模块。 本地控制器模块与一次性盒子电子通信，并且适于从分析模块接收和存储测量数据。 ISF提取装置包括穿透构件，其被配置为穿透和驻留在使用者皮肤层的目标部位中，并且随后从其提取ISF样品。 该装置还包括适于向目标部位附近的使用者皮肤层施加压力的压力环。 该装置被构造成使得压力环能够以振荡方式施加压力，从而减轻由穿透构件提取的ISF样品的ISF葡萄糖滞后。 提供ISF的方法包括提供具有穿透构件和压力环的ISF流体提取装置。 接下来，用户的皮肤层被压力环接触并被穿透构件穿透。 然后从用户的皮肤层提取ISF样品，同时通过压力环以振荡方式施加压力。 振荡压力降低了提取的ISF样品的ISF葡萄糖滞后。

    Cassette of lancet cartridges for sampling blood
    3.
    发明申请
    Cassette of lancet cartridges for sampling blood 有权
    用于取样血液的柳叶刀墨盒盒

    公开(公告)号：US20040009100A1

    公开(公告)日：2004-01-15

    申请号：US10282927

    申请日：2002-10-28

    Applicant: Agilent Technologies, Inc.

    Inventor： Tad Decatur Simons ,  Michael Greenstein ,  Dominique M. Freeman ,  Leslie Anne Leonard ,  David A. King ,  Paul Lum

    IPC: B01L003/00

    CPC classification number: A61B5/157 ,  A61B5/150022 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15113 ,  A61B5/15153 ,  A61B5/15159 ,  A61B5/15165 ,  A61B5/15174 ,  A61B2562/0295 ,  Y10S436/808

    Abstract: A cassette containing cartridges for sampling blood from a patient. The cassette includes a container for storing a plurality of cartridges and at least one cartridge in the container. The cartridge includes a cartridge case and a lancet. The lancet has a tip and is housed in the cartridge case. The lancet can be driven to extend the tip outside the cartridge case for lancing the skin of the patient to yield blood. The container has a compartment that contains at least one cartridge. A cartridge from the compartment can be loaded onto a glucometer that drives the lancet in the cartridge to lance the skin of a patient.

    Abstract translation: 包含用于从患者取血的药筒的药盒。 盒式磁带包括用于存储多个盒的容器和容器中的至少一个盒。 药筒包括药筒盒和刺血针。 刺血针具有尖端并且容纳在盒壳体中。 可以驱动柳叶刀将尖端延伸到药筒壳体外部，以便撕裂患者的皮肤以产生血液。 容器具有包含至少一个盒的隔间。 来自隔室的药筒可以被装载到驱动药筒中的刺血针的血糖仪上以刺穿患者的皮肤。

    Methods and apparatus for an analyte detecting device
    5.
    发明申请
    Methods and apparatus for an analyte detecting device 审中-公开
    分析物检测装置的方法和装置

    公开(公告)号：US20110034829A9

    公开(公告)日：2011-02-10

    申请号：US11534977

    申请日：2006-09-25

    Applicant: Dominique Freeman

    Inventor： Dominique Freeman

    IPC: A61B5/00 ,  B65B55/00 ,  B27N3/08

    CPC classification number: A61B5/15176 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15159 ,  A61B5/15161

    Abstract: In one embodiment according to the present invention, a device is provided comprising a cartridge having a plurality of cavities. The device may include a plurality of penetrating members at least partially contained in the cavities of the single cartridge wherein the penetrating members are slidably movable to extend outward from lateral openings on the cartridge to penetrate tissue. The device may have a sterility barrier coupled to the cartridge, wherein the sterility barrier covers a plurality of the lateral openings, and wherein the sterility barrier covering the lateral openings is configured to be moved so that a penetrating member exits the lateral opening without contacting the barrier. The device may include a plurality of analyte detecting members coupled to the cartridge and a plurality of sample capture devices, wherein the sample capture devices each having an opening there through to allow a penetrating member to pass through.

    Abstract translation: 在根据本发明的一个实施例中，提供了包括具有多个空腔的盒的装置。 该装置可以包括至少部分地容纳在单个盒的空腔中的多个穿透构件，其中穿透构件可滑动地移动以从盒上的侧向开口向外延伸以穿透组织。 该装置可以具有耦合到盒的无菌屏障，其中无菌屏障覆盖多个侧向开口，并且其中覆盖侧向开口的无菌屏障构造成移动，使得穿透构件离开侧向开口而不接触 屏障。 该装置可以包括耦合到盒的多个分析物检测构件和多个样品捕获装置，其中每个样品捕获装置在其上具有开口以允许穿透构件通过。

    Devices and methods for accessing and analyzing physiological fluid
    10.
    发明申请
    Devices and methods for accessing and analyzing physiological fluid 有权
    用于获取和分析生理液体的装置和方法

    公开(公告)号：US20030212347A1

    公开(公告)日：2003-11-13

    申请号：US10143253

    申请日：2002-05-09

    Inventor： Borzu Sohrab

    IPC: A61B005/00

    CPC classification number: A61B5/15159 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150442 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150862 ,  A61B5/150969 ,  A61B5/15126 ,  A61B5/15146 ,  A61B5/15153 ,  A61B5/157

    Abstract: Systems, devices and methods for determining the concentration of physiological fluid analytes are provided. The subject systems have a plurality of biosensor devices present on a disposable cartridge. Each biosensor device includes a biosensor and a skin penetration means. In practicing the subject methods, a movement means of the device is used to move each biosensor device in a first direction that provides for penetration of the skin-piercing means into a skin layer followed by movement of the biosensor in a second direction that provides for removal of the skin-piercing means from the skin layer, where this movement profile provides for physiological fluid access and analyte concentration determination by the analyte sensor means. The subject systems, devices and methods for using the same find use in determining the concentration of a variety of different physiological fluid analytes, and are particularly suited for use in detection of physiological fluid glucose concentration.

    Abstract translation: 提供了用于确定生理流体分析物浓度的系统，装置和方法。 主题系统具有存在于一次性盒中的多个生物传感器装置。 每个生物传感器装置包括生物传感器和皮肤穿透装置。 在实施主题方法时，使用该装置的移动装置沿着第一方向移动每个生物传感器装置，该第一方向提供皮肤刺穿装置穿透皮肤层，随后生物传感器沿第二方向移动，该第二方向提供 从皮肤层去除皮肤刺穿装置，其中该运动分布提供生物流体通过和分析物传感器装置的分析物浓度测定。 用于使用相同发现的主题系统，装置和方法可用于确定各种不同生理液体分析物的浓度，并且特别适用于检测生理液体葡萄糖浓度。

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