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公开(公告)号：US20110028392A1
公开(公告)日：2011-02-03
申请号：US12901178
申请日：2010-10-08
CPC分类号： A23L1/3053 , A23L33/18 , A61K38/05 , A61K45/06 , C07K5/06026
摘要： The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acids (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.
摘要翻译： 本发明提供了包含含有支链氨基酸（BCAA）的二肽的可口服给药的营养产品。 在一个实施方案中，营养产品包含选自以下至少一种的二肽：丙氨酰 - 亮氨酸，丙氨酰 - 异亮氨酸，丙氨酰缬氨酸，甘氨酰 - 亮氨酸，甘氨酰 - 异亮氨酸和甘氨酰 - 缬氨酸。
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公开(公告)号：US20170157242A1
公开(公告)日：2017-06-08
申请号：US14959107
申请日：2015-12-04
IPC分类号： A61K39/39 , A61K39/35 , A61K31/702 , A61K31/19 , A61K35/747 , A61K31/715
CPC分类号： A61K39/39 , A23L1/296 , A23L1/3008 , A23L1/3014 , A23L1/3053 , A23L1/308 , A23L33/10 , A23L33/115 , A23L33/125 , A23L33/13 , A23L33/135 , A23L33/18 , A23L33/40 , A23V2002/00 , A23Y2220/73 , A61K31/19 , A61K31/702 , A61K31/715 , A61K35/747 , A61K39/35 , A61K2035/115 , A61K2039/542 , A61K2039/55 , A61K2039/55511 , A61K2039/55594 , A61K2039/577 , A61K2300/00 , A23V2200/30 , A23V2200/304 , A23V2200/3202 , A23V2200/3204 , A23V2250/1578 , A23V2250/1582 , A23V2250/16 , A23V2250/161 , A23V2250/1614 , A23V2250/1618 , A23V2250/1868 , A23V2250/28 , A23V2250/304 , A23V2250/5034 , A23V2250/55 , A23V2250/702 , A23V2250/7042 , A23V2250/7044 , A23V2250/7046 , A23V2250/705 , A23V2250/7052 , A23V2250/7056 , A23V2250/706 , A23V2250/71 , A23V2250/712 , A23V2250/714 , A23V2250/72
摘要： Provided are nutritional compositions comprising a combination of a probiotic, dietary butyrate and/or a component for stimulating butyrate production in the human gut. Further disclosed are methods of accelerating tolerance to cow's milk allergy in a pediatric subject by providing said nutritional compositions to a target subject.
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公开(公告)号：US07989418B2
公开(公告)日：2011-08-02
申请号：US12089970
申请日：2006-10-26
CPC分类号： A23L1/3053 , A23L33/18 , A61K38/05 , A61K45/06 , C07K5/06026
摘要： The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acid (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.
摘要翻译： 本发明提供一种可口服给药的营养产品，其包含含有支链氨基酸（BCAA）的二肽。 在一个实施方案中，营养产品包含选自以下至少一种的二肽：丙氨酰 - 亮氨酸，丙氨酰 - 异亮氨酸，丙氨酰缬氨酸，甘氨酰 - 亮氨酸，甘氨酰 - 异亮氨酸和甘氨酰 - 缬氨酸。
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公开(公告)号：US20140296162A1
公开(公告)日：2014-10-02
申请号：US13994222
申请日：2011-12-16
CPC分类号： A23L1/3053 , A23J3/08 , A23J3/16 , A23L33/115 , A23L33/16 , A23L33/17 , A23L33/175 , A23L33/18 , A23L33/185 , A23L33/19 , A23L33/30 , A23L33/40 , A23V2002/00 , A23V2250/70 , A61K31/20 , A61K33/06 , A61K35/20 , A61K38/011 , A61K38/018 , A61K38/02 , A61K38/168 , A23V2200/302 , A23V2250/54252 , A23V2250/1578 , A23V2250/161 , A23V2250/18 , A23V2200/316 , A23V2200/16
摘要： The invention relates to a sterilized liquid or semi-solid acid enteral composition comprising per 100 ml 9 to 20 g of non-hydrolysed globular proteins, fat and at least 100 mg of divalent metal cations and having a pH ranging between 3 and 5. The invention further relates to a method for preparing a composition according to the invention, comprising a step wherein at least the non-hydrolysed globular proteins are subjected to a direct steam injection (DSI) at specific holding values, such as a holding temperature of 100 to 140° C. during a holding time of about 0.5 to 10 seconds, followed by a homogenization step and a sterilization step The composition according to the invention has a reduced astringency and can be used for medical purposes, such as for stimulating muscle protein synthesis in a mammal, in particular for treating sarcopenia, and for specific groups of people, such as elderly and sportsman.
摘要翻译： 本发明涉及一种无菌液体或半固体酸肠内组合物，其包含每100毫升9-20克非水解球状蛋白质，脂肪和至少100mg二价金属阳离子，pH值在3至5之间。 本发明还涉及一种制备根据本发明的组合物的方法，其包括至少将所述非水解球状蛋白质以特定保持值（例如保持温度为100至 在约0.5至10秒的保持时间内保持140℃，然后进行均化步骤和灭菌步骤根据本发明的组合物具有减少的涩味，并且可用于医学目的，例如用于刺激肌肉蛋白质合成 哺乳动物，特别是用于治疗肌肉减少症，以及针对特定群体的老年人和运动员。
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公开(公告)号：US20090170786A1
公开(公告)日：2009-07-02
申请号：US12089970
申请日：2006-10-26
IPC分类号： A61K38/05 , C07C229/00
CPC分类号： A23L1/3053 , A23L33/18 , A61K38/05 , A61K45/06 , C07K5/06026
摘要： The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acid (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.
摘要翻译： 本发明提供一种可口服给药的营养产品，其包含含有支链氨基酸（BCAA）的二肽。 在一个实施方案中，营养产品包含选自以下至少一种的二肽：丙氨酰 - 亮氨酸，丙氨酰 - 异亮氨酸，丙氨酰缬氨酸，甘氨酰 - 亮氨酸，甘氨酰 - 异亮氨酸和甘氨酰 - 缬氨酸。
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公开(公告)号：US08486888B2
公开(公告)日：2013-07-16
申请号：US12901178
申请日：2010-10-08
CPC分类号： A23L1/3053 , A23L33/18 , A61K38/05 , A61K45/06 , C07K5/06026
摘要： The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acids (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.
摘要翻译： 本发明提供了包含含有支链氨基酸（BCAA）的二肽的可口服给药的营养产品。 在一个实施方案中，营养产品包含选自以下至少一种的二肽：丙氨酰 - 亮氨酸，丙氨酰 - 异亮氨酸，丙氨酰缬氨酸，甘氨酰 - 亮氨酸，甘氨酰 - 异亮氨酸和甘氨酰 - 缬氨酸。
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公开(公告)号：US20130059928A1
公开(公告)日：2013-03-07
申请号：US13698108
申请日：2011-05-16
IPC分类号： A23J3/32 , A61K8/64 , A61K47/42 , C07K1/12 , C07K14/415
CPC分类号： A23L1/3053 , A23J3/14 , A23J3/32 , A23L33/18 , A23P10/30
摘要： A method for preparing alkaline hydrolysates of plant proteins, which includes the following steps: 1) preparing a suspension of proteins selected from the group consisting of pea proteins, potato proteins and maize proteins, at a dry matter content of between 10 and 15%; 2) adjusting the pH, with stirring, to a value between 9.5 and 10.5 using, as the only alkaline agent, one or more alkali metal hydroxides selected from the group consisting of sodium hydroxide and potassium hydroxide; 3) heating the resulting suspension at a temperature between 70 and 80° C., for 4 to 6 hours; 4) neutralizing said heated suspension using an inorganic acid, preferably hydrochloric acid; 5) drying the neutralized suspension so as to obtain the alkaline hydrolysate.
摘要翻译： 一种制备植物蛋白质碱性水解物的方法，其包括以下步骤：1）以干物质含量为10至15％制备选自豌豆蛋白，马铃薯蛋白和玉米蛋白的蛋白质悬浮液; 2）使用一种或多种选自氢氧化钠和氢氧化钾的碱金属氢氧化物作为唯一碱性试剂，在搅拌下将pH调节至9.5至10.5之间。 3）将得到的悬浮液在70-80℃的温度下加热4至6小时; 4）使用无机酸，优选盐酸中和所述加热的悬浮液; 5）干燥中和的悬浮液，得到碱性水解产物。
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公开(公告)号：US20110123514A1
公开(公告)日：2011-05-26
申请号：US12992530
申请日：2009-05-14
申请人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
发明人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
CPC分类号： A23L1/3053 , A23J1/20 , A23L33/18 , A23L33/19 , A61K38/00 , C07K14/515
摘要： The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.
摘要翻译： 本发明提供了用于富集血管生成素的乳提取物的方法，所述方法涉及通过大小，电荷或免疫亲和力分离。 本发明还提供了通过该方法产生的血管生成素富集的提取物，并将其提供于药物和营养组合物以及用于治疗可被血管生成素治疗的多种疾病或病症的食物。
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公开(公告)号：US20100168040A1
公开(公告)日：2010-07-01
申请号：US12293722
申请日：2007-03-23
IPC分类号： A61K38/05 , A61P21/00 , C07C229/26
CPC分类号： A23L1/3053 , A23L33/18 , A23V2002/00 , A61K38/05 , A23V2200/316
摘要： A muscle fatigue remedy that for persons with the symptoms of muscle pain attributed to strenuous exercise, lassitude in the arms and legs attributed to acute exercise, lower back pain and stiffness in the shoulder attributed to taking of a certain posture over a prolonged period of time, etc., relieves the symptoms and allows them to have a fulfilling life. There is provided a muscle fatigue remedy containing alanylglutamine or its salt as an active ingredient.
摘要翻译： 肌肉疲劳补救措施，适用于剧烈运动引起肌肉疼痛症状的人员，由于急性运动引起的胳膊和腿部疲劳，腰部疼痛和肩部僵硬导致长时间服用某种姿势 等等，减轻症状，使他们有一个充实的生活。 提供了含有丙氨酰谷氨酰胺或其盐作为活性成分的肌肉疲劳补救剂。
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公开(公告)号：US09247766B2
公开(公告)日：2016-02-02
申请号：US12992530
申请日：2009-05-14
申请人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
发明人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
CPC分类号： A23L1/3053 , A23J1/20 , A23L33/18 , A23L33/19 , A61K38/00 , C07K14/515
摘要： The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.
摘要翻译： 本发明提供了用于富集血管生成素的乳提取物的方法，所述方法涉及通过大小，电荷或免疫亲和力分离。 本发明还提供了通过该方法产生的血管生成素富集的提取物，并将其提供于药物和营养组合物以及用于治疗可被血管生成素治疗的多种疾病或病症的食物。
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