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公开(公告)号：US20150275188A1
公开(公告)日：2015-10-01
申请号：US14661219
申请日：2015-03-18
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols from the fatty acid biosynthetic pathway, as well as methods of their use.
Abstract translation: 提供了从脂肪酸生物合成途径产生脂肪醇的基因工程细胞和微生物以及它们使用的方法。
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公开(公告)号：US20110256599A1
公开(公告)日：2011-10-20
申请号：US13099986
申请日：2011-05-03
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
IPC: C12P7/04 , C07C31/125 , C12N1/15 , C12N1/19 , C12N1/21
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols from the fatty acid biosynthetic pathway, as well as methods of their use.
Abstract translation: 提供了从脂肪酸生物合成途径产生脂肪醇的基因工程细胞和微生物以及它们使用的方法。
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公开(公告)号：US08283143B2
公开(公告)日：2012-10-09
申请号：US13099986
申请日：2011-05-03
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
IPC: C07C31/125 , C12P7/04 , C12N1/15 , C12N1/21
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols from the fatty acid biosynthetic pathway, as well as methods of their use.
Abstract translation: 提供了从脂肪酸生物合成途径产生脂肪醇的基因工程细胞和微生物以及它们使用的方法。
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公开(公告)号：US20100251601A1
公开(公告)日：2010-10-07
申请号：US12278960
申请日：2008-03-28
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered cells and microorganisms are provided that produce products from the fatty acid biosynthetic pathway (fatty acid derivatives), as well as methods of their use. The products are particularly useful as biofuels.
Abstract translation: 提供了从脂肪酸生物合成途径（脂肪酸衍生物）产生产物的基因工程细胞和微生物以及它们的使用方法。 该产品特别适用于生物燃料。
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公开(公告)号：US09017984B2
公开(公告)日：2015-04-28
申请号：US13529990
申请日：2012-06-21
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
IPC: C12N1/00 , C12N1/20 , C12N1/12 , C12P7/64 , C12N1/16 , C12N1/14 , C10L1/02 , C10L1/19 , C11C3/00
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered microorganisms that produce fatty alcohols from a sugar source by way of the fatty acid biosynthetic pathway, as well as methods of their use are provided.
Abstract translation: 提供了通过脂肪酸生物合成途径从糖源产生脂肪醇的基因工程微生物，以及它们的使用方法。
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Patent Agency Ranking
公开(公告)号：US20120264983A1
公开(公告)日：2012-10-18
申请号：US13529990
申请日：2012-06-21
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered microorganisms that produce fatty alcohols from a sugar source by way of the fatty acid biosynthetic pathway, as well as methods of their use are provided.
Abstract translation: 提供了通过脂肪酸生物合成途径从糖源产生脂肪醇的基因工程微生物，以及它们的使用方法。
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公开(公告)号：US08110670B2
公开(公告)日：2012-02-07
申请号：US12278960
申请日：2008-03-28
Applicant: Zhihao Hu , Fernando Valle
Inventor： Zhihao Hu , Fernando Valle
CPC classification number: C07C69/533 , C07C69/34 , C07C69/52 , C10L1/02 , C10L1/026 , C10L1/19 , C11C3/003 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/16 , C12N9/93 , C12P7/6409 , C12P7/6436 , C12P7/6463 , C12P7/649 , C12Y102/01 , C12Y301/02 , C12Y602/01 , C12Y604/01 , Y02E50/13 , Y02E50/343
Abstract: Genetically engineered cells and microorganisms are provided that produce products from the fatty acid biosynthetic pathway (fatty acid derivatives), as well as methods of their use. The products are particularly useful as biofuels.
Abstract translation: 提供了从脂肪酸生物合成途径（脂肪酸衍生物）产生产物的基因工程细胞和微生物以及它们的使用方法。 该产品特别适用于生物燃料。
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公开(公告)号：US20130071908A1
公开(公告)日：2013-03-21
申请号：US13600109
申请日：2012-08-30
Applicant: Marguerite A. CERVIN , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Karl J. Sanford , Joseph C. McAuliffe , Frank J. Feher , Aaron S. Puhala , Andrei Miasnikov , Richard La Duca , Caroline M. Peres
Inventor： Marguerite A. CERVIN , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Karl J. Sanford , Joseph C. McAuliffe , Frank J. Feher , Aaron S. Puhala , Andrei Miasnikov , Richard La Duca , Caroline M. Peres
CPC classification number: C12P5/007 , C12N9/1022 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y203/01009 , C12Y207/01036 , C12Y401/01033 , C12Y402/03027 , C12Y503/03002 , Y02E50/343
Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
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公开(公告)号：US08349599B2
公开(公告)日：2013-01-08
申请号：US13228758
申请日：2011-09-09
Applicant: Robert M. Caldwell , M. Harunur Rashid , Fernando Valle
Inventor： Robert M. Caldwell , M. Harunur Rashid , Fernando Valle
Abstract: Described are multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate. The complexes having a dehydrogenase subunit and a cytochrome C subunit. Also described are polynucleotides coding for the multimeric complexes and methods of use thereof.
Abstract translation: 描述了在碳底物的酶转化中起作用的多聚体氧化还原酶复合物。 具有脱氢酶亚基和细胞色素C亚基的复合物。 还描述了编码多聚体复合物的多核苷酸及其使用方法。
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10.发明申请Method of Creating a Library of Bacterial Clones with Varying Levels of Gene Expression 有权创建不同基因表达水平的细菌克隆库的方法公开(公告)号：US20120015849A1
公开(公告)日：2012-01-19
申请号：US13155290
申请日：2011-06-07
Applicant: Philippe Soucaille , Marguerite A. Cervin , Fernando Valle
Inventor： Philippe Soucaille , Marguerite A. Cervin , Fernando Valle
CPC classification number: C12N15/1086 , C40B40/08 , C40B50/06
Abstract: The present invention relates to a method of creating DNA libraries that include an artificial promoter library and/or a modified ribosome binding site library and transforming bacterial host cells with the library to obtain a population of bacterial clones having a range of expression levels for a chromosomal gene of interest.
Abstract translation: 本发明涉及一种创建包含人源启动子文库和/或修饰的核糖体结合位点文库的DNA文库的方法，并用文库转化细菌宿主细胞，以获得具有染色体表达水平范围的细菌克隆群 感兴趣的基因
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