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    Method for identifying genes encoding signal sequences
    1.
    发明申请
    Method for identifying genes encoding signal sequences 审中-公开
    识别编码信号序列的基因的方法

    公开(公告)号：US20050164393A1

    公开(公告)日：2005-07-28

    申请号：US11048658

    申请日：2005-01-25

    Applicant: Sean McCarthy ,  Steven Bossone

    Inventor： Sean McCarthy ,  Steven Bossone

    IPC: C12N1/19 ,  C12N15/10 ,  C12N15/81 ,  C12Q1/68 ,  C12N1/18 ,  C12N15/74

    CPC classification number: C12Q1/6897 ,  C12N15/1034 ,  C12N15/1051 ,  C12N15/81

    Abstract: The invention involves a method of identifying nucleic acid sequences encoding signal peptide-containing proteins. The method features chimeric constructs containing a KRE9 gene that lacks a signal sequence. Yeast containing chimeric KRE9 plasmid constructs that encode signal sequences are selected based on their ability to grow on media in which sucrose is the sole carbon source.

    Abstract translation: 本发明涉及鉴定编码含有信号肽的蛋白质的核酸序列的方法。 该方法具有含有缺少信号序列的KRE9基因的嵌合构建体。 基于它们在其中蔗糖是唯一碳源的培养基上生长的能力来选择含有编码信号序列的嵌合KRE9质粒构建体的酵母。

    PASSIVE MAGNETIC BEARING
    2.
    发明申请
    PASSIVE MAGNETIC BEARING 审中-公开
    被动磁性轴承

    公开(公告)号：US20110001379A1

    公开(公告)日：2011-01-06

    申请号：US12829457

    申请日：2010-07-02

    Applicant: Sean McCarthy ,  Seamus Flanagan ,  Alan Simpson ,  Maxime Sorin

    Inventor： Sean McCarthy ,  Seamus Flanagan ,  Alan Simpson ,  Maxime Sorin

    IPC: H02K7/09

    CPC classification number: F16C32/0425 ,  F16C19/10 ,  F16C32/0402

    Abstract: A passive magnetic bearing which has an exceptionally low friction couple. Radial and axial restraint is achieved through magnetic and mechanical means. The embodiment of the passive magnetic bearing has two axially magnetized rings, which each exhibit at least one pair of north and south poles. The magnetized rings are positioned in a manner where the poles are in a repulsive magnetic interaction such that the plane of symmetry which separates the like poles lies perpendicular to the axis of the rotation of a shaft and this radially constrains the movement of the shaft. Axial rigidity is added to the system by the use of ceramic bearings and related axial retaining mechanisms on one of the ring magnets thus maintaining the magnetic bearing in an otherwise unstable axial plane.

    Abstract translation: 一种具有极低摩擦力的无源磁轴承。 通过磁力和机械方式实现径向和轴向约束。 无源磁轴承的实施例具有两个轴向磁化的环，每个环表现出至少一对北极和南极。 磁化环以这样的方式定位，其中磁极处于排斥磁相互作用，使得分离相同磁极的对称平面垂直于轴的旋转轴线，并且这径向地限制轴的运动。 通过在其中一个环形磁体上使用陶瓷轴承和相关的轴向保持机构将轴向刚度加到系统上，从而将磁轴承保持在另外不稳定的轴向平面。

    Method and apparatus for determining if an optical disk originated from a valid source
    5.
    发明授权
    Method and apparatus for determining if an optical disk originated from a valid source 失效
    用于确定光盘是否源自有效源的方法和装置

    公开(公告)号：US08098924B2

    公开(公告)日：2012-01-17

    申请号：US12108180

    申请日：2008-04-23

    Applicant: Patrick Smith ,  Phelim O'Doherty ,  Sean McCarthy

    Inventor： Patrick Smith ,  Phelim O'Doherty ,  Sean McCarthy

    IPC: G06K9/00 ,  G01N21/00

    CPC classification number: G11B23/281 ,  G11B5/865 ,  G11B7/263 ,  G11B20/00086

    Abstract: A method and apparatus for determining if an optical disk originated from a valid source, the method and apparatus scanning one major surface of the optical disk for imperfections, storing the locations of the imperfections relative to a datum, comparing a parameter of each of the locations of the imperfections with corresponding parameters of a master disk of known source for determining if the disk originated from the source from which the master disk originated.

    Abstract translation: 一种用于确定光盘是否源自有效源的方法和装置，所述方法和装置扫描光盘的一个主表面以获得缺陷，存储缺陷相对于基准的位置，比较每个位置的参数 具有已知源的主盘的相应参数的缺陷，用于确定盘是否源自主盘的源。

    ELECTRIC MOTOR WITH NO COUNTER ELECTROMOTIVE FORCE
    7.
    发明申请
    ELECTRIC MOTOR WITH NO COUNTER ELECTROMOTIVE FORCE 有权
    无电机电动马达

    公开(公告)号：US20110227440A1

    公开(公告)日：2011-09-22

    申请号：US12967741

    申请日：2010-12-14

    Applicant: Sean McCarthy ,  Seamus Flanagan ,  Alan Simpson ,  Maxime Sorin

    Inventor： Sean McCarthy ,  Seamus Flanagan ,  Alan Simpson ,  Maxime Sorin

    IPC: H02K21/12

    CPC classification number: H02K29/10 ,  H02K1/12 ,  H02K21/14 ,  H02K53/00

    Abstract: An electromagnetic motor system with no counter/back electromotive force due to the ability of the system to change from one magnetic state to another magnetic state in a defined sequence. In the first state a kinetic energy component is added to the system's rotor where two permanent magnetic materials, which are affixed to the rotor, are allowed to come into an angular range such that they act in a symmetrical manner on a fixed soft ferromagnetic material. This fixed soft ferromagnetic material also acts as the core of an electromagnetic coil and when the rotor's permanent magnets are at the closest proximity to the soft ferromagnetic core a voltage is applied across the coil, resulting in the soft ferromagnetic coil being saturated in a horizontal manner where previously it was polarized in a vertical manner while under the influence of the rotor's two permanent magnets.

    Abstract translation: 由于系统以一定的顺序从一个磁状态转变为另一个磁状态的能力，所以不具有反电动势的电磁电动机系统。 在第一状态下，将动能分量添加到系统的转子中，其中固定在转子上的两个永久磁性材料被允许进入角度范围，使得它们以对称的方式在固定的软铁磁材料上作用。 该固定的软铁磁材料也用作电磁线圈的核心，并且当转子的永磁体与软铁磁芯最接近时，线圈上施加电压，导致软铁磁线圈以水平方式饱和 其中以前它在垂直方向上被极化，同时在转子的两个永磁体的影响下。

    Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
    9.
    发明申请
    Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof 审中-公开
    Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和整合素α亚基蛋白和核酸分子及其用途

    公开(公告)号：US20060122373A1

    公开(公告)日：2006-06-08

    申请号：US11175714

    申请日：2005-07-05

    Applicant: Sean McCarthy ,  David Gearing ,  Douglas Holtzman ,  Yang Pan ,  Samantha Busfield ,  Thomas Barnes ,  Charles Mackay ,  Jose Lora

    Inventor： Sean McCarthy ,  David Gearing ,  Douglas Holtzman ,  Yang Pan ,  Samantha Busfield ,  Thomas Barnes ,  Charles Mackay ,  Jose Lora

    IPC: C07K14/705 ,  C07K14/715 ,  C07H21/04 ,  C12P21/06

    CPC classification number: C12Q1/48 ,  A61K38/00 ,  C07K14/47 ,  C07K2319/00 ,  C12Q1/6876

    Abstract: The invention provides novel Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 polypeptides, proteins, and nucleic acid molecules. In addition to isolated, full-length Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 proteins, the invention further provides isolated Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 fusion proteins, antigenic peptides and anti-Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 antibodies. The invention also provides Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 or A259 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

    Abstract translation: 本发明提供新颖的Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259多肽，蛋白质和核酸分子。 除了分离的全长Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259蛋白外，本发明还提供了分离的Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259融合 蛋白质，抗原肽和抗Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259抗体。 本发明还提供了Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞， 已经引入或破坏了Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129或A259基因的人类转基因动物。 还提供利用本发明组合物的诊断，筛选和治疗方法。

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