Invention Application
US20060122373A1 Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
审中-公开
Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和整合素α亚基蛋白和核酸分子及其用途
- Patent Title: Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
- Patent Title (中): Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和整合素α亚基蛋白和核酸分子及其用途
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Application No.: US11175714Application Date: 2005-07-05
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Publication No.: US20060122373A1Publication Date: 2006-06-08
- Inventor: Sean McCarthy , David Gearing , Douglas Holtzman , Yang Pan , Samantha Busfield , Thomas Barnes , Charles Mackay , Jose Lora
- Applicant: Sean McCarthy , David Gearing , Douglas Holtzman , Yang Pan , Samantha Busfield , Thomas Barnes , Charles Mackay , Jose Lora
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K14/715 ; C07H21/04 ; C12P21/06
Abstract:
The invention provides novel Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 polypeptides, proteins, and nucleic acid molecules. In addition to isolated, full-length Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 proteins, the invention further provides isolated Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 fusion proteins, antigenic peptides and anti-Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 antibodies. The invention also provides Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 or A259 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
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