公开(公告)号：US10007100B2

公开(公告)日：2018-06-26

申请号：US14924435

申请日：2015-10-27

Applicant: OLYMPUS CORPORATION

Inventor： Yu Kikuchi

IPC: G02B21/00 ,  G02B21/16

CPC classification number: G02B21/0048 ,  G02B21/16

Abstract: A light sheet illumination microscope includes a detection optical system and an illumination optical system. The illumination optical system includes a first optical element for forming a sheet-shaped illumination beam that travels in a first direction and that has a width in a second direction that is perpendicular to both the optical axis of the detection optical system and the first direction in a specimen, and a scanner that relatively scans the specimen with the sheet-shaped illumination beam in the second direction.

公开(公告)号：US10018819B2

公开(公告)日：2018-07-10

申请号：US15094847

申请日：2016-04-08

Applicant: OLYMPUS CORPORATION

Inventor： Yoshihito Iguchi ,  Yu Kikuchi

IPC: G02B21/06 ,  G02B21/00 ,  G02B21/16 ,  G02B21/36

CPC classification number: G02B21/06 ,  G02B21/0032 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/367

Abstract: A light sheet illumination microscope includes an illumination optical system configured to illuminate a sample from a direction substantially perpendicular to an optical axis of a detection optical system. The illumination optical system includes a first optical element configured to convert light emitted from a light source into a light sheet that forms an illumination area having a sheet shape substantially perpendicular to the optical axis of the detection optical system when the sample is irradiated with the light sheet. The illumination optical system further includes a second optical element that configured to act on the light emitted from the light source such that the light sheet is converged, diverged or diffracted in a width direction of the light sheet.

公开(公告)号：US09841591B2

公开(公告)日：2017-12-12

申请号：US14546910

申请日：2014-11-18

Applicant: OLYMPUS CORPORATION

Inventor： Yu Kikuchi

IPC: G02B21/00 ,  G02B21/12 ,  G02B21/16 ,  G01N21/64 ,  G02B7/16 ,  G02B21/24 ,  G02B27/10 ,  G02B27/14

CPC classification number: G02B21/0076 ,  G01N21/645 ,  G01N21/6456 ,  G01N21/6458 ,  G02B7/16 ,  G02B21/12 ,  G02B21/16 ,  G02B21/248 ,  G02B27/1006 ,  G02B27/141

Abstract: A microscope is a microscope that switches an observation method between the bright-field observation and the fluorescence observation. The microscope includes an objective that irradiates a sample with excitation light and converts fluorescence from the sample into a parallel light flux, a beam splitter that splits fluorescence and excitation light from each other, and a collective lens that is arranged in such a manner that it is freely set in and removed from an optical path between the beam splitter and the objective, that has a positive power, and that is set in the optical path for fluorescence observation and is removed from the optical path for bright-field observation.