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    Fermentative production of organic compounds
    4.
    发明授权
    Fermentative production of organic compounds 失效
    发酵生产有机化合物

    公开(公告)号：US08741599B2

    公开(公告)日：2014-06-03

    申请号：US12094626

    申请日：2006-11-27

    申请人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    发明人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    IPC分类号： C12P23/00 ,  C12P19/14 ,  C12P19/02 ,  C12P13/04 ,  C12P13/08 ,  C12P13/00 ,  C12P7/66 ,  C12P1/00 ,  C12P19/38 ,  C12P7/14 ,  C12N1/00 ,  C12N1/20

    CPC分类号： C12P13/08 ,  C12N1/20 ,  C12N1/22

    摘要： A process for the fermentative production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least one 1 N atom, comprising the following steps: a1) milling a starch feedstock, thus obtaining a millbase which comprises at least part of the nonstarchy solid constituents of the starch feedstock; a2) suspending the millbase in an aqueous liquid and hydrolysis of the starch portion in the millbase by enzymatic liquefaction and, if appropriate, subsequent saccharification, whereby a first liquid (1) which comprises mono- or oligosaccharides is obtained; and b) addition of the liquid (1) which comprises mono- or oligosaccharides together with metabolizable mono-, di- or oligosaccharides or together with a composition which comprises metabolizable mono-, di- or oligosaccharide in a concentration of at least 50% by weight and which is essentially free from solids which are insoluble in water to a fermentation medium comprising a microorganism which is capable of overproducing the organic compound under fermentation conditions.

    摘要翻译： 一种用于发酵生产至少一种具有至少3个C原子或具有至少2个C原子和至少一个1 N原子的有机化合物的方法，包括以下步骤：a1）研磨淀粉原料，从而获得一种 包括淀粉原料的至少部分非淀粉样固体成分; a2）将研磨料悬浮在含水液体中，并通过酶液化和适当的后续糖化水解淀粉部分，由此获得包含单糖或寡糖的第一液体（1）; 和b）添加包含单糖或寡糖以及可代谢的单糖，二糖或寡糖的液体（1），或与包含至少50％浓度的可代谢的单糖，二糖或寡糖的组合物一起加入 并且其基本上不含不溶于包含微生物的发酵培养基的固体，所述微生物能够在发酵条件下过量产生有机化合物。

    Fermentative production of fine chemicals
    6.
    发明申请
    Fermentative production of fine chemicals 有权
    发酵精细化学品生产

    公开(公告)号：US20090162892A1

    公开(公告)日：2009-06-25

    申请号：US11597782

    申请日：2005-05-27

    申请人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    发明人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    IPC分类号： C12P23/00 ,  C12P1/00 ,  C12P21/00 ,  C12P19/38 ,  C12P19/30 ,  C12P19/12 ,  C12P19/04 ,  C12P13/04 ,  C12P17/18 ,  C12P17/12 ,  C12P7/64 ,  C12P7/40 ,  C12P7/48 ,  C12P7/46 ,  C12P7/42 ,  C12P7/26 ,  C12P7/02

    CPC分类号： C12P25/00 ,  C12P7/46 ,  C12P13/02 ,  C12P13/08 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/24 ,  C12P19/02 ,  C12P19/14 ,  C12P19/20 ,  Y02P20/582

    摘要： The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of sugar-based microbial fermentation, comprising: a) the preparation of a sugar-containing liquid medium with a monosaccharide content of more than 20% by weight from a starch feedstock, the sugar-containing liquid medium also comprising non-starchy solid constituents of the starch feedstock; b) the fermentation of the sugar-containing liquid medium for the production of the metabolite(s); and c) depletion or isolation of at least one metabolite from the fermentation liquor, wherein a microorganism strain which produces the desired metabolite(s) is cultivated with the sugar-containing liquid medium, said liquid medium being obtained by: a1) milling the starch feedstock; and a2) liquefying the millbase in an aqueous liquid in the presence of at least one starch-liquefying enzyme, followed by saccharification using at least one saccharifying enzyme, where at least some of the millbase is liquefied by continuous or batchwise addition to the aqueous liquid.

    摘要翻译： 本发明涉及通过糖基微生物发酵生产具有至少3个碳原子或至少2个碳原子和至少1个氮原子的至少一种微生物代谢物的方法，包括：a）制备 含糖液体介质，其单糖含量大于淀粉原料的20重量％以上，所述含糖液体介质还包含淀粉原料的非淀粉状固体成分; b）用于生产代谢物的含糖液体培养基的发酵; 和c）从所述发酵液中消耗或分离至少一种代谢物，其中产生所需代谢物的微生物菌株与所述含糖液体培养基一起培养，所述液体培养基通过以下步骤获得：a1）研磨所述淀粉 原料; 和a2）在至少一种淀粉 - 液化酶的存在下在水性液体中液化所述研磨料，然后使用至少一种糖化酶进行糖化，其中至少一些所述絮凝液通过连续或分批添加至所述水性液体而液化 。

    Fermentative Production of Organic Compounds
    7.
    发明申请
    Fermentative Production of Organic Compounds 失效
    有机化合物的发酵生产

    公开(公告)号：US20080299606A1

    公开(公告)日：2008-12-04

    申请号：US12094626

    申请日：2006-11-27

    申请人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    发明人： Markus Pompejus ,  Stephan Freyer ,  Markus Lohscheidt ,  Oskar Zelder ,  Matthias Boy

    IPC分类号： C12P23/00 ,  C12P1/00 ,  C12P21/04 ,  C12P13/00 ,  C12P7/64 ,  C12P7/18 ,  C12P7/40 ,  C12P19/38 ,  C12P19/40 ,  C12P19/30

    CPC分类号： C12P13/08 ,  C12N1/20 ,  C12N1/22

    摘要： A process for the fermentative production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least one 1 N atom, comprising the following steps: a1) milling a starch feedstock, thus obtaining a millbase which comprises at least part of the nonstarchy solid constituents of the starch feedstock; a2) suspending the millbase in an aqueous liquid and hydrolysis of the starch portion in the millbase by enzymatic liquefaction and, if appropriate, subsequent saccharification, whereby a first liquid (1) which comprises mono- or oligosaccharides is obtained; and b) addition of the liquid (1) which comprises mono- or oligosaccharides together with metabolizable mono-, di- or oligosaccharides or together with a composition which comprises metabolizable mono-, di- or oligosaccharide in a concentration of at least 50% by weight and which is essentially free from solids which are insoluble in water to a fermentation medium comprising a microorganism which is capable of overproducing the organic compound under fermentation conditions.

    摘要翻译： 一种用于发酵生产至少一种具有至少3个C原子或具有至少2个C原子和至少一个1 N原子的有机化合物的方法，包括以下步骤：a1）研磨淀粉原料，从而获得一种 包括淀粉原料的至少部分非淀粉样固体成分; a2）将研磨料悬浮在含水液体中，并通过酶液化和适当的后续糖化水解淀粉部分，由此获得包含单糖或寡糖的第一液体（1）; 和b）添加包含单糖或寡糖以及可代谢的单糖，二糖或寡糖的液体（1），或与包含至少50％浓度的可代谢的单糖，二糖或寡糖的组合物一起加入 并且其基本上不含不溶于包含微生物的发酵培养基的固体，所述微生物能够在发酵条件下过量产生有机化合物。

    Enzyme Granulate l Containing Phytase
    10.
    发明申请
    Enzyme Granulate l Containing Phytase 审中-公开
    含有植酸酶的酶颗粒

    公开(公告)号：US20090274795A1

    公开(公告)日：2009-11-05

    申请号：US11991837

    申请日：2006-09-11

    申请人： Markus Lohscheidt ,  Roland Betz ,  Jörg Braun ,  Wolf Pelletier ,  Peter Ader

    发明人： Markus Lohscheidt ,  Roland Betz ,  Jörg Braun ,  Wolf Pelletier ,  Peter Ader

    IPC分类号： C12N9/16 ,  A23L1/30

    CPC分类号： C12Y301/03026 ,  A23K20/189 ,  A23K40/10 ,  A23K40/20 ,  A23K40/25 ,  A23K40/30

    摘要： The present invention relates to novel phytase-comprising enzyme granules, those particles of which have A) a core which comprises at least one phytase and at least one solid carrier material suitable for feeds, and b) a coating arranged on the core, the cores of the particles or the entire particle, after if appropriate required grinding, on suspension or dissolution in demineralized water at 25° C. giving a pH in the range from 4.5 to 6.5, preferably in the range from 4.6 to 6.0, and particularly preferably from 4.7 to 5.5 and which are suitable as feed additives, and also a method for production thereof. The invention also relates to the use of the phytase-comprising enzyme granules in feed compositions and, in particular, pelleted feed compositions, which are obtainable using the phytase-comprising enzyme granules.

    摘要翻译： 本发明涉及新颖的含有植酸酶的酶颗粒，其中的颗粒具有A）包含至少一种植酸酶和至少一种适用于饲料的固体载体材料的芯，以及b）布置在芯上的涂层，芯 的颗粒或整个颗粒，如果合适的话需要研磨，在25℃的软化水中悬浮或溶解，得到4.5至6.5，优选在4.6至6.0范围内，特别优选为 4.7〜5.5，适合作为饲料添加剂，也可以是其制造方法。 本发明还涉及含有植酸酶的酶颗粒在饲料组合物中的用途，特别是使用含有植酸酶的酶颗粒可获得的颗粒饲料组合物。