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1.发明申请COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE FREE OF C5 HYDROCARBONS UNDER DECOUPLING CONDITIONS AND/OR SAFE OPERATING RANGES 审中-公开在解除条件和/或安全操作范围内生产不含C5碳氢化合物的异丙苯的组合物和方法公开(公告)号：US20160281112A1
公开(公告)日：2016-09-29
申请号：US14973485
申请日：2015-12-17
发明人： Anthony R. CALABRIA , Marguerite A. CERVIN , Gopal K. CHOTANI , Richard LA DUCA , Joseph C. MCAULIFFE , Michael C. MILLER , Timothy A. SABO , Karl J. SANFORD , Erin L. WEBSTER , Gregory M. WHITED
CPC分类号： C12P5/007 , C07C11/18 , C12N9/88 , C12N15/52 , C12N15/70 , C12N15/74 , C12N15/75 , C12N15/80 , C12P5/02 , C12Y402/03027 , Y02E50/343
摘要： The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a nonflammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
摘要翻译： 本发明的特征在于从培养细胞产生异戊二烯的方法，其中固定相中的细胞。 本发明还提供包含这些培养细胞和/或增加量的异戊二烯的组合物。 本发明还提供了在气相中包含不可燃浓度的异戊二烯的体系。 此外，本发明提供了异戊二烯组合物，例如具有增加量的异戊二烯或增加的纯度的组合物。
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公开(公告)号：US20180273982A1
公开(公告)日：2018-09-27
申请号：US15873761
申请日：2018-01-17
发明人： Marguerite A. CERVIN , Gopal K. CHOTANI , Frank J. FEHER , Richard LA DUCA , Joseph C. MCAULIFFE , Andrei MIASNIKOV , Caroline M. PERES , Aaron S. PUHALA , Karl J. SANFORD , Fernando VALLE , Gregory M. WHITED
CPC分类号： C12P5/007 , C12N9/1022 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y203/01009 , C12Y207/01036 , C12Y401/01033 , C12Y402/03027 , C12Y503/03002 , Y02E50/343
摘要： The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
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公开(公告)号：US20140128645A1
公开(公告)日：2014-05-08
申请号：US13722991
申请日：2012-12-20
IPC分类号： C12P5/00
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03027
摘要： The invention provides for methods for the production of isoprene in recombinant marine bacterial cells via the heterologous expression of isoprene synthase enzymes.
摘要翻译： 本发明提供了通过异戊二烯合酶的异源表达在重组海洋细菌细胞中生产异戊二烯的方法。
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公开(公告)号：US20220324786A1
公开(公告)日：2022-10-13
申请号：US17634600
申请日：2020-08-25
申请人： DANISCO US INC.
发明人： Juho JÄRVINEN , Hannu KOIVIKKO , Jyrki KUUSISTO , Tero Tuomas MENTUNEN , Juha NURMI , Pertti Matias SÄRELÄ , Jani SIITONEN , Gregory M. WHITED
摘要： Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, comprising subjecting the aqueous solution comprising said X-MVA to a purification step to produce a purified solution and crystallizing said X-MVA from said purified solution by water solvent crystallization. Methods are also provided for producing mevalonolactone from an aqueous solution comprising X-MVA, comprising subjecting the aqueous solution comprising said X-MVA to cation exchange thereby converting said aqueous solution comprising X-MVA to an aqueous solution comprising mevalonolactone (MVL). Methods are also provided for producing mevalonolactone monohydrate crystals.
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公开(公告)号：US20180066287A1
公开(公告)日：2018-03-08
申请号：US15677335
申请日：2017-08-15
发明人： Anthony R. CALABRIA , Marguerite A. CERVIN , Gopal K. CHOTANI , Richard LA DUCA , Joseph C. MCAULIFFE , Michael C. MILLER , Timothy A. SABO , Karl J. SANFORD , Erin L. Spring , Gregory M. WHITED
IPC分类号： C12P5/00 , C12N15/80 , C12N15/75 , C12N15/74 , C12N15/70 , C12N15/52 , C07C11/18 , C12P5/02 , C12N9/88
CPC分类号： C12P5/007 , C07C11/18 , C12N9/88 , C12N15/52 , C12N15/70 , C12N15/74 , C12N15/75 , C12N15/80 , C12P5/02 , C12Y402/03027 , Y02E50/343
摘要： The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
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6.发明申请COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 审中-公开包含各种保护素和/或细菌体的组合物及其用途公开(公告)号：US20130135979A1
公开(公告)日：2013-05-30
申请号：US13741292
申请日：2013-01-14
申请人： Danisco US Inc.
发明人： Richard R. BOTT , Rasmus B. JENSEN , Bradley R. KELEMEN , Donald E. WARD, II , Gregory M. WHITED
IPC分类号： G11B7/242
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译： 本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定化混合物。 蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材 和塑料材料，其中所述固体材料沉积在所述基底上。 本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。
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公开(公告)号：US20220331219A1
公开(公告)日：2022-10-20
申请号：US17634620
申请日：2020-08-25
申请人： DANISCO US INC.
发明人： Heli ANGLENIUS , Carole GHERARDI , Laura Tiina Maria HUUSKONEN , Juho JÄRVINEN , Henrik Max JENSEN , Hannu KOIVIKKO , Jyrki KUUSISTO , Tero Tuomas MENTUNEN , Juha NURMI , Piera Mattia PERICU , Pertti Matias SÄRELÄ , Jani SIITONEN , Kirsti TIIHONEN , Gregory M. WHITED
摘要： Compositions comprising mevalonolactone, mevalonic add, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof and methods of use are provided for topical application for skin care, skin supplement, hair care, and oral care. More specifically, the present disclosure is directed towards compositions comprising mevalonolactone, mevalonic acid, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof for providing a skin care benefit and/or multiple skin care benefits.
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8.发明申请PRODUCTION OF ISOPRENE, ISOPRENOID, AND ISOPRENOID PRECURSORS USING AN ALTERNATIVE LOWER MEVALONATE PATHWAY 审中-公开使用替代的下层梅花路线生产异丙苯，异丙苯和异丙苯前驱物公开(公告)号：US20160002672A1
公开(公告)日：2016-01-07
申请号：US14654424
申请日：2013-12-20
发明人： Zachary Q. BECK , Jörg MAMPEL , Guido MEURER , Michael C. MILLER , Karl J. SANFORD , Dmitrii V. VAVILINE , Walter WEYLER , Gregory M. WHITED
CPC分类号： C12P5/007 , C07C11/18 , C07F9/09 , C12N9/1229 , C12N9/88 , C12P9/00 , C12Y207/04026 , C12Y401/01 , Y02E50/343
摘要： The invention provides for compositions and methods for the production of isoprene, isoprenoid precursor, and/or isoprenoids in cells via the expression (e.g., heterologous expression) of phosphomevalonate decarboxylases and/or isopentenyl kinases.
摘要翻译： 本发明提供了通过磷酸戊糖醛酸脱羧酶和/或异戊烯基激酶的表达（例如异源表达）在细胞中产生异戊二烯，类异戊二烯前体和/或类异戊二烯的组合物和方法。
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公开(公告)号：US20140073026A1
公开(公告)日：2014-03-13
申请号：US14028342
申请日：2013-09-16
IPC分类号： C12P5/00
摘要： The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity.
摘要翻译： 本发明的特征在于从培养细胞产生异戊二烯的方法。 本发明还提供包括这些培养细胞的组合物。 本发明提供异戊二烯组合物，例如具有增加的异戊二烯量或增加的纯度的组合物。 另外，本发明提供了通过在适合异戊二烯生产的条件下培养细胞同时维持细胞活力和/或代谢活性来生产异戊二烯的方法。
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10.发明申请COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE FREE OF C5 HYDROCARBONS UNDER DECOUPLING CONDITIONS AND/OR SAFE OPERATING RANGES 有权在解除条件和/或安全操作范围内生产不含C5碳氢化合物的异丙苯的组合物和方法公开(公告)号：US20130196402A1
公开(公告)日：2013-08-01
申请号：US13741149
申请日：2013-01-14
发明人： Anthony R. CALABRIA , Marguerite A. CERVIN , Gopal K. CHOTANI , Richard LA DUCA , Joseph C. MCAULIFFE , Michael C. MILLER , Timothy A. SABO , Karl J. SANFORD , Erin L. WEBSTER , Gregory M. WHITED
IPC分类号： C12P5/02
CPC分类号： C12P5/007 , C07C11/18 , C12N9/88 , C12N15/52 , C12N15/70 , C12N15/74 , C12N15/75 , C12N15/80 , C12P5/02 , C12Y402/03027 , Y02E50/343
摘要： The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
摘要翻译： 本发明的特征在于从培养细胞产生异戊二烯的方法，其中固定相中的细胞。 本发明还提供包含这些培养细胞和/或增加量的异戊二烯的组合物。 本发明还提供了在气相中包含不可燃浓度的异戊二烯的体系。 此外，本发明提供了异戊二烯组合物，例如具有增加量的异戊二烯或增加的纯度的组合物。
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