-
公开(公告)号：US20150284785A1
公开(公告)日：2015-10-08
申请号：US14474274
申请日：2014-09-01
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Ralf Bickel , Torsten Schulz , Thomas Ullrich
IPC: C12Q1/68
CPC classification number: C12Q1/6837 , B01F11/0045 , B01L3/5027 , B01L3/502746 , B01L7/52 , B01L7/525 , B01L2200/027 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0877 , B01L2300/1827 , B01L2300/1838 , B01L2400/0481 , G01N21/6452 , G01N21/6458
Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
Abstract translation: 本发明涉及用于检测分析物的装置和方法。 特别地，本发明涉及用于定性和/或定量检测分析物的方法，其包括在基底上的微阵列，探针分子固定在阵列元件上，所述微阵列设置在装置的第一表面上; 以及检测室，形成在包括设置在其上的微阵列的第一表面和第二表面之间，其中微阵列和第二表面之间的距离是可变的，并且其中第二表面具有位移结构。
-
公开(公告)号：US20180088115A1
公开(公告)日：2018-03-29
申请号：US15719522
申请日：2017-09-28
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Ralf Bickel , Torsten Schulz , Thomas Ullrich , Jens Tuchscheerer
CPC classification number: G01N33/56966 , B01F11/0045 , B01F11/0266 , B01F13/0059 , B01L3/50273 , B01L3/502746 , B01L2200/027 , B01L2300/0636 , B01L2300/0822 , B01L2300/0825 , B01L2400/0481 , G01N21/03 , G01N35/0099 , G01N2021/0346 , G01N2035/00346
Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
-
Patent Agency Ranking
公开(公告)号：US20180085751A1
公开(公告)日：2018-03-29
申请号：US15649628
申请日：2017-07-13
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Torsten Schulz , Thomas Ellinger , Daniel Weicherding
CPC classification number: B01L3/502707 , B01L2300/0636 , B01L2300/069 , B01L2300/0877 , B01L2400/0481 , C12Q1/6834
Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.
-
公开(公告)号：US20190004054A1
公开(公告)日：2019-01-03
申请号：US15893675
申请日：2018-02-11
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Thomas Kaiser , Jens Tuchscheerer , Vico Beier , Torsten Schulz , Anke Wostemeyer
Abstract: A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. Capillary structures of the devices or used in the methods may comprise a matrix and the devices may comprise control elements and methods for assaying of sample may use corresponding controlling activities.
-
公开(公告)号：US09580745B2
公开(公告)日：2017-02-28
申请号：US14474274
申请日：2014-09-01
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Ralf Bickel , Torsten Schulz , Thomas Ullrich
CPC classification number: C12Q1/6837 , B01F11/0045 , B01L3/5027 , B01L3/502746 , B01L7/52 , B01L7/525 , B01L2200/027 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0877 , B01L2300/1827 , B01L2300/1838 , B01L2400/0481 , G01N21/6452 , G01N21/6458
Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
Abstract translation: 本发明涉及用于检测分析物的装置和方法。 特别地，本发明涉及用于定性和/或定量检测分析物的方法，其包括在基底上的微阵列，探针分子固定在阵列元件上，所述微阵列设置在装置的第一表面上; 以及检测室，形成在包括设置在其上的微阵列的第一表面和第二表面之间，其中微阵列和第二表面之间的距离是可变的，并且其中第二表面具有位移结构。
-
公开(公告)号：US20150197822A1
公开(公告)日：2015-07-16
申请号：US14499221
申请日：2014-09-28
Applicant: CLONDIAG GMBH
Inventor： Katrin Steinmetzer , Eugen Ermantraut , Torsten Schulz , Thomas Kaiser , Thomas Ullrich
CPC classification number: C12Q1/703 , B01J19/0046 , B01J2219/00527 , B01J2219/00576 , B01J2219/00605 , B01J2219/00659 , B01J2219/00695 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , B01L3/502738 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L7/52 , B01L9/527 , B01L2200/0647 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2300/0816 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/701 , C12Q2600/158
Abstract: A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative of the presence and/or amount of the target molecules, a micro fluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the micro fluidic network.
Abstract translation: 一种包括刚性基底的装置，至少部分地覆盖基底的柔性覆盖元件，形成在基底中的适于容纳液体并适于释放一个或多个细胞，孢子或病毒的内容物的第一结构，所述内容物包括 目标分子，形成在基底中的第二结构，适于容纳液体，并且包括适于捕获靶分子的至少一个结合成分，并用于确定指示靶分子的存在和/或量的值;微流体网络 至少互连第一结构和第二结构，以及致动器构件，其适于通过将柔性覆盖元件压靠在衬底上来选择性地关闭微流体网络的一部分来实现第一结构和第二结构之间的流体流动。
-
公开(公告)号：US09791441B2
公开(公告)日：2017-10-17
申请号：US13919524
申请日：2013-06-17
Applicant: CLONDIAG GMBH
Inventor： Eugen Ermantraut , Ralf Bickel , Torsten Schulz , Thomas Ullrich , Jens Tuchscheerer
CPC classification number: G01N33/56966 , B01F11/0045 , B01F11/0266 , B01F13/0059 , B01L3/50273 , B01L3/502746 , B01L2200/027 , B01L2300/0636 , B01L2300/0822 , B01L2300/0825 , B01L2400/0481 , G01N21/03 , G01N35/0099 , G01N2021/0346 , G01N2035/00346
Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
-
-
-
-
-
-
Search Results
7
records
(took 0.021 seconds)
