公开(公告)号：US20120277413A1

公开(公告)日：2012-11-01

申请号：US13454023

申请日：2012-04-23

申请人： Juergen Schmitz ,  Andrzej Dzionek ,  David William Buck

发明人： Juergen Schmitz ,  Andrzej Dzionek ,  David William Buck

IPC分类号： C07K14/435 ,  C07H21/04

CPC分类号： C07K14/7056 ,  C07K16/2851 ,  Y10S435/81

摘要： The invention provides antigen-binding fragments specific for dendritic cells and effective in treatment and/or diagnosing a variety of disorders. Methods of use are also provided as are methods for screening for additional such antigen-binding fragments and the products obtained thereby.

摘要翻译： 本发明提供对树突状细胞特异性的抗原结合片段，并有效治疗和/或诊断多种病症。 还提供了用于筛选额外的这种抗原结合片段的方法和由此获得的产物。

公开(公告)号：US08183039B2

公开(公告)日：2012-05-22

申请号：US11393155

申请日：2006-03-29

申请人： Juergen Schmitz ,  David William Buck ,  Andrzej Dzionek

发明人： Juergen Schmitz ,  David William Buck ,  Andrzej Dzionek

IPC分类号： C12N5/00 ,  C12N5/02 ,  C07K1/00 ,  C12Q1/24

CPC分类号： C07K14/7056 ,  C07K16/2851 ,  Y10S435/81

摘要： The application describes, inter alia, a method for isolating or enriching for dendritic cells from a mixture of human cells involving contacting cells in the mixture with an antibody that binds BDCA-4, or antigen-binding fragment thereof, under conditions in which the antibody or antigen-binding fragment binds BDCA-4+ dendritic cells, and separating dendritic cells bound by the antibody or antigen-binding fragment from other cells in the mixture.

摘要翻译： 该申请尤其描述了一种用于从人细胞混合物中分离或富集树突状细胞的方法，包括使混合物中的细胞与结合BDCA-4或其抗原结合片段的抗体在其中抗体 或抗原结合片段结合BDCA-4 +树突状细胞，并将由抗体结合的树突状细胞或与混合物中的其他细胞的抗原结合片段分离。

公开(公告)号：US20070252346A1

公开(公告)日：2007-11-01

申请号：US11811683

申请日：2007-06-12

申请人： Stephen Steadings ,  William Buck ,  Christopher Barton

发明人： Stephen Steadings ,  William Buck ,  Christopher Barton

IPC分类号： B23B31/12

CPC分类号： B23B31/1238 ,  B23B31/123 ,  B23B2231/06 ,  B23B2231/38 ,  B23B2231/44 ,  Y10S279/902 ,  Y10T279/17632 ,  Y10T279/32 ,  Y10T408/953

摘要： A chuck for use with a manual or powered driver having a housing and a rotatable drive shaft extending therefrom is provided. The chuck includes a generally cylindrical body member having a nose section and a tail section. Each of a plurality of jaws is slidably positioned in one of a plurality of angularly disposed passageways in the body. Each jaw has a jaw face formed on one side thereof and threads formed on the opposite side thereof. A nut is rotatably mounted on the body in engagement with the jaw threads so that rotation of the nut moves the jaws axially within the passageways. A locking member, in a first axial position, is rotatable with respect to the driver housing. In a second axial position, it operatively engages the housing and the nut so that the locking member is rotationally held to the housing and the nut so that the nut is rotationally held to the housing. The locking member is axially reciprocal between the first axial position and the second axial position.

公开(公告)号：US20070184991A1

公开(公告)日：2007-08-09

申请号：US11655330

申请日：2007-01-19

申请人： Mark Winemiller ,  Douglas Deckman ,  William Maxwell ,  William Buck ,  David Baillargeon

发明人： Mark Winemiller ,  Douglas Deckman ,  William Maxwell ,  William Buck ,  David Baillargeon

IPC分类号： C10M155/04 ,  C10M129/74

CPC分类号： C10M105/38 ,  C10M107/02 ,  C10M111/02 ,  C10M127/06 ,  C10M141/06 ,  C10M169/04 ,  C10M169/044 ,  C10M169/045 ,  C10M2203/06 ,  C10M2203/065 ,  C10M2203/1025 ,  C10M2205/02 ,  C10M2205/0206 ,  C10M2205/173 ,  C10M2205/22 ,  C10M2205/223 ,  C10M2207/28 ,  C10M2207/2805 ,  C10M2207/283 ,  C10M2207/2835 ,  C10M2209/1023 ,  C10M2215/28 ,  C10N2220/021 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2230/54 ,  C10N2240/10 ,  C10N2260/14

摘要： The present invention concerns friction reducers for use in lubricating oil compositions which comprise certain groups of aromatic compounds, esters, narrow mixtures of base stocks, and/or amorphous polymers such as amorphous olefin copolymers. These compositions can provide substantial reductions in the coefficient of friction and fuel economy improving benefits when admixed to lubricating oils without deleterious effects such as instability, undesirable high viscosities and deposits. In one aspect of the invention, pentaerythritol esters and optionally triol esters are added to lubricating oil compositions to provide reduced friction and improved fuel economy. In a second aspect of the invention, similar results are obtained by adding hydrocarbyl aromatics to a lubricating oil composition containing one or more of Groups II and III base stock. In a third aspect, the invention concerns a lubricating oil composition comprising an amorphous olefin copolymer and one or more of Groups II and III base stocks. In one embodiment, the third aspect also includes one or more of hydrocarbyl aromatics and polyol esters as part of the composition. In a fourth aspect, moderate concentrations of hydrocarbyl aromatics are used in a lubricating oil composition comprising paraffinic base oil stocks and preferably a borated polyisobutenyl succinimide ashless dispersant.

摘要翻译： 本发明涉及用于润滑油组合物中的摩擦减少剂，其包含某些芳族化合物，酯，基础油料的混合物和/或无定形聚合物如无定形烯烃共聚物。 当混合到润滑油上时，这些组合物可以显着降低摩擦系数和燃料经济性，而不会产生有害影响，例如不稳定性，不希望的高粘度和沉积物。 在本发明的一个方面，将季戊四醇酯和任选的三醇酯加入到润滑油组合物中以提供降低的摩擦和改善的燃料经济性。 在本发明的第二方面，通过将烃基芳族化合物加入到含有II和III族基础油中的一种或多种的润滑油组合物中可获得类似的结果。 在第三方面，本发明涉及包含无定形烯烃共聚物和II和III族基料中的一种或多种的润滑油组合物。 在一个实施方案中，第三方面还包括作为组合物的一部分的一种或多种烃基芳族化合物和多元醇酯。 在第四方面，中等浓度的烃基芳族化合物用于包含石蜡基油原料，优选硼酸化聚异丁烯基琥珀酰亚胺无灰分散剂的润滑油组合物中。

公开(公告)号：US20070163408A1

公开(公告)日：2007-07-19

申请号：US11333854

申请日：2006-01-17

申请人： William Buck ,  David Peot

发明人： William Buck ,  David Peot

IPC分类号： B26D7/06 ,  B27B3/28

CPC分类号： B27G19/08 ,  B27G19/02 ,  Y10T83/727 ,  Y10T83/732

摘要： An improved riving knife/guard assembly for a table saw allows the guard to be removed and attached without the use of any tools, provides a clear view of the work zone, blade and workpiece, and is easily adjustable to accommodate different size workpieces and cutting angle. The assembly includes a riving knife extending upward from the table substantially coplanar with the saw blade and a guard that releasably attaches to the riving knife with a rotatable latch with the guard at least partially surrounding the saw blade.

摘要翻译： 用于台锯的改进的刀具/护罩组件允许在不使用任何工具的情况下移除和附接护罩，提供工作区域，刀片和工件的清晰视图，并且易于调节以适应不同尺寸的工件和切割 角度。 该组件包括从工作台向上延伸的铆刀，其与锯片基本上共面，并且具有可释放地附接到铆钉刀的防护件，其具有可旋转的闩锁，其中防护件至少部分地围绕锯片。

公开(公告)号：US20060276350A1

公开(公告)日：2006-12-07

申请号：US11444773

申请日：2006-06-01

申请人： Jacob Habeeb ,  William Buck ,  Douglas Deckman ,  William Maxwell

发明人： Jacob Habeeb ,  William Buck ,  Douglas Deckman ,  William Maxwell

IPC分类号： C10L1/22

CPC分类号： C10M135/10 ,  C10M129/54 ,  C10M133/04 ,  C10M133/16 ,  C10M135/36 ,  C10M159/12 ,  C10M2207/144 ,  C10M2219/044 ,  C10N2230/04 ,  C10N2230/08 ,  C10N2230/45 ,  C10N2240/102 ,  C10N2260/14 ,  C10M2219/106 ,  C10M2215/02

摘要： The present invention is directed to ashless detergents comprising the products resulting from the reaction of a salicylic acid, organic group substituted salicylic acid, sulfonic acid or organic groups substituted sulfur acid with thiadiazole or organic group substituted thiadiazole or an alkyl primary or secondary amine, and to formulated lubricating oils containing said ashless detergents.

摘要翻译： 本发明涉及无水洗涤剂，其包含由水杨酸，有机基取代的水杨酸，磺酸或有机基取代的硫酸与噻二唑或有机基取代的噻二唑或烷基伯或仲胺反应得到的产物，以及 配制含有所述无灰洗涤剂的润滑油。

公开(公告)号：US20060175769A1

公开(公告)日：2006-08-10

申请号：US11378841

申请日：2006-03-17

申请人： Mark Huggins ,  Stephen Steadings ,  James Weinhold ,  William Buck

发明人： Mark Huggins ,  Stephen Steadings ,  James Weinhold ,  William Buck

IPC分类号： B23B31/12

CPC分类号： B25B23/0035 ,  B23B31/1071 ,  B23B31/1238 ,  B23B31/1253 ,  B23B2231/38 ,  B23B2231/44 ,  B25B23/0007 ,  Y10S279/902 ,  Y10S279/904 ,  Y10T279/17008 ,  Y10T279/17145 ,  Y10T279/17196 ,  Y10T279/17623 ,  Y10T279/17632 ,  Y10T279/17811 ,  Y10T279/29 ,  Y10T408/953

摘要： A chuck includes a generally cylindrical body and a plurality of jaws reciprocally disposed in the body in communication with a central bore in the body. A first detent extends radially into the central bore and is releasable in a radially outward direction. Upon insertion of an elongated tool shaft having a polygonal cross section into the bore so that a groove in the tool shaft is aligned with the first detent, the first detent engages the groove and axially retains the tool shaft. Upon movement of the jaws so that the jaw faces engage flat sides of the tool shaft, the jaws rotationally retain the tool shaft.

公开(公告)号：US20060153651A1

公开(公告)日：2006-07-13

申请号：US11371798

申请日：2006-03-09

申请人： Stephen Steadings ,  William Buck ,  Christopher Barton

发明人： Stephen Steadings ,  William Buck ,  Christopher Barton

IPC分类号： B23B31/10

CPC分类号： B23B31/1238 ,  B23B31/123 ,  B23B2231/06 ,  B23B2231/38 ,  B23B2231/44 ,  Y10S279/902 ,  Y10T279/17632 ,  Y10T279/32 ,  Y10T408/953

摘要： A chuck for use with a manual or powered driver having a housing and a rotatable drive shaft extending therefrom is provided. The chuck includes a generally cylindrical body member having a nose section and a tail section. Each of a plurality of jaws is slidably positioned in one of a plurality of angularly disposed passageways in the body. Each jaw has a jaw face formed on one side thereof and threads formed on the opposite side thereof. A nut is rotatably mounted on the body in engagement with the jaw threads so that rotation of the nut moves the jaws axially within the passageways. A locking member, in a first axial position, is rotatable with respect to the driver housing. In a second axial position, it operatively engages the housing and the nut so that the locking member is rotationally held to the housing and the nut so that the nut is rotationally held to the housing. The locking member is axially reciprocal between the first axial position and the second axial position.

公开(公告)号：US20060079411A1

公开(公告)日：2006-04-13

申请号：US11284509

申请日：2005-11-22

申请人： Mark Winemiller ,  Douglas Deckman ,  William Maxwell ,  William Buck ,  David Baillargeon

发明人： Mark Winemiller ,  Douglas Deckman ,  William Maxwell ,  William Buck ,  David Baillargeon

IPC分类号： C10M139/00

CPC分类号： C10M169/04 ,  C10M105/38 ,  C10M107/02 ,  C10M111/02 ,  C10M111/04 ,  C10M127/06 ,  C10M141/06 ,  C10M169/041 ,  C10M169/044 ,  C10M2201/10 ,  C10M2203/06 ,  C10M2203/065 ,  C10M2203/10 ,  C10M2203/1006 ,  C10M2203/1025 ,  C10M2205/02 ,  C10M2205/0206 ,  C10M2205/0225 ,  C10M2205/0245 ,  C10M2205/028 ,  C10M2205/0285 ,  C10M2205/163 ,  C10M2205/173 ,  C10M2205/22 ,  C10M2205/223 ,  C10M2207/024 ,  C10M2207/28 ,  C10M2207/2805 ,  C10M2207/283 ,  C10M2207/2835 ,  C10M2209/1023 ,  C10M2215/28 ,  C10M2219/081 ,  C10M2219/086 ,  C10N2220/021 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2230/54 ,  C10N2240/10 ,  C10N2260/14

摘要： The present invention concerns friction reducers for use in lubricating oil compositions which comprise certain groups of aromatic compounds, esters, narrow mixtures of base stocks, and/or amorphous polymers such as amorphous olefin copolymers. These compositions can provide substantial reductions in the coefficient of friction and fuel economy improving is benefits when admixed to lubricating oils without deleterious effects such as instability, undesirable high viscosities and deposits. In one aspect of the invention, pentaerythritol esters and optionally triol esters are added to lubricating oil compositions to provide reduced friction and improved fuel economy. In a second aspect of the invention, similar results are obtained by adding hydrocarbyl aromatics to a lubricating oil composition containing one or more of Groups II and III base stock. In a third aspect, the invention concerns a lubricating oil composition comprising an amorphous olefin copolymer and one or more of Groups II and III base stocks. In one embodiment, the third aspect also includes one or more of hydrocarbyl aromatics and polyol esters as part of the composition. In a forth aspect, moderate concentrations of hydrocarbyl aromatics are used in a lubricating oil composition comprising paraffinic base oil stocks and preferably a borated polyisobutenyl succinimide ashless dispersant.

摘要翻译： 本发明涉及用于润滑油组合物中的摩擦减少剂，其包含某些芳族化合物，酯，基础油料的混合物和/或无定形聚合物如无定形烯烃共聚物。 这些组合物可以显着降低摩擦系数和燃料经济性，这是改善当与润滑油混合而没有有害影响如不稳定性，不希望的高粘度和沉积物时的益处。 在本发明的一个方面，将季戊四醇酯和任选的三醇酯加入到润滑油组合物中以提供降低的摩擦和改善的燃料经济性。 在本发明的第二方面，通过将烃基芳族化合物加入到含有II和III族基础油中的一种或多种的润滑油组合物中可获得类似的结果。 在第三方面，本发明涉及包含无定形烯烃共聚物和II和III族基料中的一种或多种的润滑油组合物。 在一个实施方案中，第三方面还包括作为组合物的一部分的一种或多种烃基芳族化合物和多元醇酯。 在第四方面，中等浓度的烃基芳族化合物用于包含石蜡基油原料，优选硼酸化的聚异丁烯基琥珀酰亚胺无灰分散剂的润滑油组合物中。

公开(公告)号：US20050217445A1

公开(公告)日：2005-10-06

申请号：US11156358

申请日：2005-06-17

申请人： David Peot ,  Philip Minalga ,  George Hornick ,  William Buck ,  William Kaiser

发明人： David Peot ,  Philip Minalga ,  George Hornick ,  William Buck ,  William Kaiser

IPC分类号： B27B9/00 ,  B23D45/04 ,  B23D59/00 ,  B23Q11/06 ,  B23Q17/24 ,  B27B5/32 ,  B27G19/02

CPC分类号： B23D59/003 ,  B23D59/002 ,  B23Q11/06 ,  B23Q17/24 ,  B23Q17/2404 ,  B27B5/32 ,  B27G19/02 ,  Y10T83/7697 ,  Y10T83/7734 ,  Y10T83/7788 ,  Y10T83/828 ,  Y10T83/839 ,  Y10T83/853 ,  Y10T83/8773

摘要： A table saw such as a chop saw, a miter saw, compound miter saw or a sliding compound miter saw that is provided with a laser arbor alignment system. An opaque shield or transparent shield having an opaque mask blocks the laser beam from being projected into a range of normal operator eye positions. One or more openings in the shield or opaque mask provide a sight line on a workpiece initially. As the saw is moved into engagement with the workpiece, the shield is pivoted away from the workpiece and a solid laser line is projected on the workpiece.

摘要翻译： 台锯如切割锯，斜切锯，复合斜切锯或设置有激光轴对准系统的滑动复合斜切锯。 具有不透明掩模的不透明屏蔽或透明屏蔽件阻挡激光束投射到正常操作者眼睛位置的范围内。 屏蔽或不透明掩模中的一个或多个开口最初在工件上提供视线。 当锯被移动成与工件接合时，屏蔽件远离工件枢转，并且将实心激光线投影到工件上。