-
公开(公告)号：US20220213675A1
公开(公告)日：2022-07-07
申请号：US17608977
申请日：2020-05-14
Applicant: Karl-Josef Kramer , Werner Kramer
Inventor： Karl-Josef Kramer , Werner Kramer
Abstract: A toilet device with inspection functions, highly controllable cleaning, drying, visual observation and reporting functions. Certain embodiments of such observation, inspection, cleaning and drying of the user's posterior and genitals are introduced in some detail, and so are the automatic self-cleaning and drying mechanisms, structures and methods of the observation and cleaning devices. This device allows the user to take full control of observing their bowel movement as well as controlling proper cleaning and drying afterwards. In addition, toilet device embodiments are presented which can be combined with the described observation and cleaning features and which support people lacking mobility, strength or coordination or having sensory impairments by executing certain bodily motions, such as bringing the user into a more or less crouching or rocking position in order to facilitate bowel movement. For all actuations, activation via voice, push button, touch screen or joystick control are all envisioned.
-
2.发明申请Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof 审中-公开新型杂环核苷酸衍生物，含有这些化合物的药物及其用途公开(公告)号：US20100261664A1
公开(公告)日：2010-10-14
申请号：US12786943
申请日：2010-05-25
Applicant: Wendelin FRICK , Heiner GLOMBIK , Werner KRAMER , Hubert HEUER , Harm BRUMMERHOP , Oliver PLETTENBURG
Inventor： Wendelin FRICK , Heiner GLOMBIK , Werner KRAMER , Hubert HEUER , Harm BRUMMERHOP , Oliver PLETTENBURG
IPC: A61K31/7042 , C07H15/18 , A61K31/7032 , C07H17/00 , C07H17/02 , A61P3/10
Abstract: Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereofThe invention relates to substituted heterocyclic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation. The compounds are suitable for example as antidiabetics.
Abstract translation: 新型杂环氟代果糖苷衍生物，含有这些化合物的药物及其用途本发明涉及式Ⅰ的取代杂环氟代果糖衍生物及其生理学上可耐受的盐及其制备方法。 该化合物适合于例如抗糖尿病药。
-
公开(公告)号：US07786103B2
公开(公告)日：2010-08-31
申请号：US11872855
申请日：2007-10-16
Applicant: Werner Kramer , Wendelin Frick
Inventor： Werner Kramer , Wendelin Frick
IPC: A61K31/397 , C07K14/435 , C07D205/04 , C07D235/02
Abstract: The invention describes a method for isolating an intestinal protein which is able to bind cholesterol and/or cholesterol uptake inhibitors.
Abstract translation: 本发明描述了一种分离能够结合胆固醇和/或胆固醇摄取抑制剂的肠蛋白的方法。
-
4.发明授权Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use 有权二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07674773B2
公开(公告)日：2010-03-09
申请号：US11155109
申请日：2005-06-17
Applicant: Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
Inventor： Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
CPC classification number: C07D205/08 , C07F7/1804
Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
Abstract translation: 其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
-
5.发明申请NOVEL 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES WHICH ARE SUBSTITUTED WITH CYCLOHEXYL GROUPS, METHOD FOR PRODUCING THE SAME, DRUGS CONTAINING SAID COMPOUNDS AND USE THEREOF 有权与环烯基组合取代的新的1,4-苯并四氢吡喃-1,1-二氧化物衍生物，其生产方法，含有化合物的药物及其用途公开(公告)号：US20100035962A1
公开(公告)日：2010-02-11
申请号：US12465920
申请日：2009-05-14
Applicant: Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC: A61K31/38 , C07D409/12 , A61P3/10 , A61P25/28 , A61P25/18
CPC classification number: C07D337/08
Abstract: This Invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with cyclohexyl groups, method for producing the same, drugs containing said compounds and use thereof.
Abstract translation: 本发明涉及用环己基取代的新的1,4-苯并噻吩-1-,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
-
Patent Agency Ranking
6.发明申请Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof 有权由苄基取代的新的1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US20100035961A1
公开(公告)日：2010-02-11
申请号：US12465911
申请日：2009-05-14
Applicant: Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC: A61K31/38 , C07D409/12 , A61P3/10 , A61P25/28 , A61P25/18
CPC classification number: C07H5/06 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H7/02 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
Abstract: This invention relates to Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof.
Abstract translation: 本发明涉及由苄基取代的新型1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途。
-
7.发明申请NOVEL DIPHENYLAZETIDINONE SUBSTITUTED BY PIPERAZINE-1-SULFONIC ACID AND HAVING IMPROVED PHARMACOLOGICAL PROPERTIES 审中-公开由哌嗪-1-磺酸取代的新型二氢吡啶酮，具有改善的药理性质公开(公告)号：US20090264402A1
公开(公告)日：2009-10-22
申请号：US12432997
申请日：2009-04-30
Applicant: Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Claus-Dieter Graf , Wolfgang Schmider
Inventor： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Claus-Dieter Graf , Wolfgang Schmider
IPC: A61K31/496 , C07D403/12 , A61P3/06 , C07D413/12
CPC classification number: C07D295/205 , C07D205/08 , C07D263/22
Abstract: The invention therefore relates to the compound of the formula I or a pharmaceutically acceptable salt thereof, its pharmaceutically composition and uses.
Abstract translation: 因此，本发明涉及式I化合物或其药学上可接受的盐，其药物组合物和用途。
-
8.发明申请USE OF INHIBITORS OF THE CELLULAR NA+/H+ EXCHANGER (NHE) FOR PREPARING A MEDICAMENT FOR NORMALIZING SERUM LIPIDS 审中-公开细胞NA + / H +交换子（NHE）的抑制剂用于制备用于正常化血清脂质的药物公开(公告)号：US20090143473A1
公开(公告)日：2009-06-04
申请号：US12364703
申请日：2009-02-03
Applicant: Hans Jochen LANG , Hans-Willi JANSEN , Jan-Robert SCHWARK , Heinz-Werner KLEEMANN , Oliver JUNG , Hans-Ludwig SCHAFER , Wolfgang LINZ , Werner KRAMER , Bernward SCHOLKENS , Eugen FALK
Inventor： Hans Jochen LANG , Hans-Willi JANSEN , Jan-Robert SCHWARK , Heinz-Werner KLEEMANN , Oliver JUNG , Hans-Ludwig SCHAFER , Wolfgang LINZ , Werner KRAMER , Bernward SCHOLKENS , Eugen FALK
IPC: A61K31/165 , A61P7/00
CPC classification number: A61K31/00 , A61K31/155 , A61K31/166 , A61K31/22 , A61K31/365 , A61K2300/00
Abstract: Use of inhibitors of the cellular Na+/H+ exchanger (NHE) for the production of a medicament for the normalization of serum lipids.The active compounds identified as inhibitors of the cellular Na+/H+ exchanger (NHE) are used for the production of a medicament for the normalization of serum lipids.They are used for the production of a medicament for lowering the blood lipid level and illnesses caused thereby, as well as the endothelial dysfunction syndrome and illness caused thereby.
Abstract translation: 使用细胞Na + / H +交换剂（NHE）的抑制剂来制备用于血清脂质标准化的药物。 鉴定为细胞Na + / H +交换体（NHE）的抑制剂的活性化合物用于制备用于血清脂质标准化的药物。 它们用于制备用于降低由此引起的血脂水平和疾病以及由此引起的内皮功能障碍综合征和疾病的药物。
-
公开(公告)号：US07435727B2
公开(公告)日：2008-10-14
申请号：US10635008
申请日：2003-08-06
Applicant: Werner Kramer , Wendelin Frick
Inventor： Werner Kramer , Wendelin Frick
IPC: A61K31/397 , C07K14/435 , C07D205/08 , C07D235/02
Abstract: The invention describes a method for isolating an intestinal protein which is able to bind cholesterol and/or cholesterol uptake inhibitors. Methods of identifying inhibitors of cholesterol uptake and related pharmaceuticals and methods of treatment also are described.
Abstract translation: 本发明描述了一种分离能够结合胆固醇和/或胆固醇摄取抑制剂的肠蛋白的方法。 还描述了鉴定胆固醇摄取抑制剂和相关药物的方法以及治疗方法。
-
10.发明授权Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权酸基取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07388004B2
公开(公告)日：2008-06-17
申请号：US11643890
申请日：2006-12-22
Applicant: Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
Inventor： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC: C07D205/08 , C07F9/568 , A61K31/397 , A61P9/10 , A61P3/06
CPC classification number: C07D205/08
Abstract: One embodiment of the invention relates to compounds of the formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of the compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
Abstract translation: 本发明的一个实施方案涉及式I化合物：其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
-
-
-
-
-
-
-
-
-
Search Results
65
records
(took 0.137 seconds)
