-
1.发明授权1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof 有权被苄基取代的1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07956085B2
公开(公告)日：2011-06-07
申请号：US12465911
申请日：2009-05-14
Applicant: Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC: A61K31/38 , C07D409/08
CPC classification number: C07H5/06 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H7/02 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
Abstract: This invention relates to Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof.
Abstract translation: 本发明涉及由苄基取代的新型1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途。
-
2.发明申请NOVEL DIPHENYLAZETIDINONE WITH IMPROVED PHYSIOLOGICAL PROPERTIES, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND ITS USE 失效具有改善的生理特性的新型二氢噻吩酮，其制备方法，包含该化合物的药物及其用途公开(公告)号：US20070197498A1
公开(公告)日：2007-08-23
申请号：US11690993
申请日：2007-03-26
Applicant: Gerhard JAEHNE , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
Inventor： Gerhard JAEHNE , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
IPC: A61K31/397 , C07D205/02
CPC classification number: C07C233/18 , C07D205/08
Abstract: Novel diphenylazetidinone, process for its preparation, medicaments comprising this compound and their use The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
Abstract translation: 新型二苯基氮杂环丁酮，其制备方法，包含该化合物的药物及其用途本发明涉及式1的化合物及其生理上可接受的盐。 该化合物例如可用作降血脂药物。
-
公开(公告)号：US20070043017A1
公开(公告)日：2007-02-22
申请号：US11544718
申请日：2006-10-10
Applicant: Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
Inventor： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC: A61K31/397 , C07D205/02 , C07D403/02
CPC classification number: C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
Abstract: One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
-
4.发明授权Combination product of a 1,4-benzothiepine 1,1-dioxide compound with at least one other active ingredient and the use of the product 有权1,4-苯并噻吩1,1-二氧化物化合物与至少一种其它活性成分的组合产物和产物的用途公开(公告)号：US07179792B2
公开(公告)日：2007-02-20
申请号：US10699967
申请日：2003-11-03
Applicant: Heiner Glombik , Wendelin Frick , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Heiner Glombik , Wendelin Frick , Hans-Ludwig Schaefer , Werner Kramer
CPC classification number: A61K45/06 , A61K31/395 , A61K31/55 , A61K2300/00
Abstract: The present invention is directed to a 1,4-benzothiepine 1,1-dioxide compound of formula I in which the radicals have the meanings defined herein, or a pharmaceutically acceptable salt or physiologically functional derivative thereof, with at least one other active ingredient, or a pharmaceutically acceptable salt or physiologically functional derivative thereof. The invention is also directed to the use of the combination product, pharmaceutical composition comprising the combination product and method for preparing the pharmaceutical composition.
Abstract translation: 本发明涉及其中基团具有本文定义的含义，或其药学上可接受的盐或生理功能衍生物的式I的1,4-苯并硫代1,1-二氧化物化合物与至少一种其它活性成分， 或其药学上可接受的盐或生理功能衍生物。 本发明还涉及组合产品，包含组合产品和方法的药物组合物用于制备药物组合物的用途。
-
5.发明授权Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use 有权二苯基氮杂环丁酮衍生物，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US06498156B2
公开(公告)日：2002-12-24
申请号：US10021028
申请日：2001-12-19
Applicant: Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schaefer
Inventor： Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schaefer
IPC: A61K31397
CPC classification number: C07D401/14 , C07D205/08 , C07D409/12
Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
Abstract translation: 其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
-
Patent Agency Ranking
6.发明授权1,4-benzothiepin-1, 1-dioxide derivatives with improved properties method for producing the same, drugs containing said compounds and the use thereof 有权具有改进性质的1,4-苯并硫氮杂_1,1-二氧化物衍生物的制备方法，含有所述化合物的药物及其用途公开(公告)号：US08106023B2
公开(公告)日：2012-01-31
申请号：US12465883
申请日：2009-05-14
Applicant: Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC: C07D281/10 , A61K31/55 , A61K31/70
CPC classification number: C07H5/06 , C07D409/12
Abstract: This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives with improved properties, method for producing the same, drugs containing said compounds and use thereof.
Abstract translation: 本发明涉及具有改进性质的新型1,4-苯并硫代-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
-
7.发明申请NOVEL 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES WHICH ARE SUBSTITUTED WITH FLUORINE, METHOD FOR PRODUCING THE SAME, DRUGS CONTAINING SAID COMPOUNDS AND USE THEREOF 有权与氟化物取代的新的1,4-苯并二氢吡喃-1,1-二氧化物衍生物，其制备方法，含有化合物的药物及其用途公开(公告)号：US20100062991A1
公开(公告)日：2010-03-11
申请号：US12465928
申请日：2009-05-14
Applicant: Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
Inventor： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
CPC classification number: C07H7/02 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H5/06 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
Abstract: This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof.
Abstract translation: 本发明涉及被氟取代的新的1,4-苯并硫代-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
-
8.发明授权Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权环取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07579339B2
公开(公告)日：2009-08-25
申请号：US11501758
申请日：2006-08-10
Applicant: Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
Inventor： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC: C07D205/08 , C07D227/00 , A61K31/397 , A61P3/06 , A61P9/10
CPC classification number: C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
Abstract: One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
Abstract translation: 本发明的一个实施方案涉及式I化合物，其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
-
公开(公告)号：US07390790B2
公开(公告)日：2008-06-24
申请号：US11544718
申请日：2006-10-10
Applicant: Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
Inventor： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC: A61K31/7052 , C07H7/02 , C07H7/04 , A61P3/06 , A61P9/10 , A61K31/397 , C07D205/08 , C07D227/00
CPC classification number: C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
Abstract: One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
-
10.发明申请Acid-group-substituted diphenylazetidinones process for their preparation, medicaments comprising these compounds, and their use 有权酸组取代的二苯基氮杂环丁烷的制备方法，包含这些化合物的药物及其用途公开(公告)号：US20070123506A1
公开(公告)日：2007-05-31
申请号：US11643890
申请日：2006-12-22
Applicant: Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
Inventor： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC: A61K31/397 , A61K31/675 , C07D205/04
CPC classification number: C07D205/08
Abstract: One embodiment of the invention relates to compounds of the formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of the compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
Abstract translation: 本发明的一个实施方案涉及式I化合物：其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
-
-
-
-
-
-
-
-
-
Search Results
61
records
(took 0.076 seconds)
