-
公开(公告)号:US20210284612A1
公开(公告)日:2021-09-16
申请号:US17315969
申请日:2021-05-10
Applicant: Vectus Biosystems Limited
Inventor: Karen Annette DUGGAN
IPC: C07D233/64 , C07D241/04 , A61P9/00 , A61P13/12 , A61P11/00 , C07D233/90 , C07D401/06 , C07D401/04 , C07D401/12 , C07D403/04 , C07D417/04 , C07D413/04 , C07D413/06 , C07D403/06 , C07D407/04 , C07D417/06 , C07D407/06 , C07D409/06 , C07D409/04 , A61P1/16 , A61P9/12
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
-
公开(公告)号:US10752578B2
公开(公告)日:2020-08-25
申请号:US15761862
申请日:2016-09-21
Applicant: Vectus Biosystems Limited
Inventor: Anthony Kaye , Nurul Quazi , George Feast , Marshnil Lakshman
IPC: C07C231/02 , C07C309/66 , C07C69/732 , C07C59/52 , C07C303/28 , C07C231/12 , C07C235/34 , C07C51/09 , C07C53/134 , C07C67/03 , C07C67/31 , C07C69/616
Abstract: The present invention relates novel methods of synthesizing terphenyl compounds and in particular to novel methods for the synthesis of a compound of Formula I or intermediates thereof.
-
公开(公告)号:US20200255384A9
公开(公告)日:2020-08-13
申请号:US16334283
申请日:2017-09-21
Applicant: VECTUS BIOSYSTEMS LIMITED
Inventor: Karen Annette DUGGAN
IPC: C07D233/64 , A61P9/12 , A61P9/00 , A61P1/16 , A61P13/12 , C07D241/04
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
-
公开(公告)号:US10035775B2
公开(公告)日:2018-07-31
申请号:US15557762
申请日:2016-03-18
Applicant: VECTUS BIOSYSTEMS LIMITED
Inventor: Karen Annette Duggan
IPC: C07D233/78 , C07C39/12 , C07C59/54 , C07C215/54 , C07C239/20 , C07D207/26 , C07D207/38 , C07D209/48 , C07D233/96 , C07D261/14 , C07D263/38 , C07D263/44
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of fibrosis and fibrosis-related conditions.
-
公开(公告)号:US20180037539A1
公开(公告)日:2018-02-08
申请号:US15558155
申请日:2016-03-18
Applicant: VECTUS BIOSYSTEMS LIMITED
Inventor: Karen Annette DUGGAN
IPC: C07C235/34 , C07H15/203 , C07D231/12 , C07D333/24 , C07C237/20 , C07D213/56
CPC classification number: C07C235/34 , C07C237/20 , C07D207/327 , C07D213/56 , C07D231/12 , C07D239/26 , C07D261/08 , C07D277/30 , C07D307/54 , C07D333/24 , C07H15/203
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of kidney and/or liver disease.
-
公开(公告)号:US11053202B2
公开(公告)日:2021-07-06
申请号:US16334283
申请日:2017-09-21
Applicant: Vectus Biosystems Limited
Inventor: Karen Annette Duggan
IPC: C07D233/64 , C07D241/04 , A61P9/00 , A61P13/12 , A61P11/00 , C07D233/90 , C07D401/06 , C07D401/04 , C07D401/12 , C07D403/04 , C07D417/04 , C07D413/04 , C07D413/06 , C07D403/06 , C07D407/04 , C07D417/06 , C07D407/06 , C07D409/06 , C07D409/04 , A61P1/16 , A61P9/12
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
-
公开(公告)号:US10183908B2
公开(公告)日:2019-01-22
申请号:US15558155
申请日:2016-03-18
Applicant: VECTUS BIOSYSTEMS LIMITED
Inventor: Karen Annette Duggan
IPC: C07H15/203 , C07C235/34 , C07D231/12 , C07D333/24 , C07D239/26 , C07D261/08 , C07C237/20 , C07D207/327 , C07D277/30 , C07D213/56 , C07D307/54
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of kidney and/or liver disease.
-
公开(公告)号:US20150065424A1
公开(公告)日:2015-03-05
申请号:US14542929
申请日:2014-11-17
Applicant: Vectus Biosystems Limited
Inventor: Karen Annette Duggan
CPC classification number: C07K14/57563 , A61K38/00 , A61K38/08 , A61K38/10 , A61K38/2278 , A61K45/06 , C07K7/06 , C07K7/08
Abstract: The invention relates to composition comprising a pharmaceutically effective amount of one or more functional vasoactive intestinal peptide (VIP) fragments, and the use of those compositions in the treatment of fibrosis, hypertension and other disorder.
Abstract translation: 本发明涉及包含药学有效量的一种或多种功能性血管活性肠肽(VIP)片段的组合物,以及这些组合物在治疗纤维化,高血压和其它病症中的用途。
-
公开(公告)号:US20210130301A1
公开(公告)日:2021-05-06
申请号:US17142586
申请日:2021-01-06
Applicant: Vectus Biosystems Limited
Inventor: Karen Annette DUGGAN
IPC: C07D239/26 , A61P11/00 , C07C39/15 , C07C215/54 , C07C233/11 , C07D207/408 , C07D213/56 , C07D237/08 , C07D261/14 , C07D263/44 , C07D277/30 , C07D401/10 , C07D403/10 , C07D333/24 , C07C233/07 , C07D231/56 , C07D235/26 , C07D235/06 , C07C59/52 , C07C275/42 , C07D213/73 , C07D277/68 , A61P11/06 , C07D231/12 , C07C211/29 , C07D207/38 , C07C255/00 , C07C271/28 , C07C217/48 , C07C261/04 , C07D241/12 , C07D309/10 , C07D233/78 , C07D261/08 , C07D209/48 , C07C237/20 , C07D207/327 , C07C237/22 , C07D307/54 , C07D249/18 , C07D209/34 , C07D263/38 , C07C307/10 , C07D207/26 , C07D207/444 , C07C235/34 , C07C311/03 , C07C311/08 , C07C239/20 , C07C235/78 , C07D209/18 , C07D263/58 , C07D215/14 , C07D207/40
Abstract: The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.
-
公开(公告)号:US20180072682A1
公开(公告)日:2018-03-15
申请号:US15557762
申请日:2016-03-18
Applicant: VECTUS BIOSYSTEMS LIMITED
Inventor: KAREN ANNETTE DUGGAN
IPC: C07D233/78 , C07C215/54 , C07D207/26 , C07D207/38 , C07D233/96 , C07D261/14 , C07D263/38 , C07C239/20 , C07D263/44 , C07D209/48 , C07C59/54 , C07C39/12
CPC classification number: C07D233/78 , C07C39/12 , C07C39/15 , C07C47/575 , C07C59/52 , C07C59/54 , C07C215/48 , C07C215/54 , C07C239/20 , C07D207/26 , C07D207/267 , C07D207/36 , C07D207/38 , C07D207/408 , C07D207/448 , C07D209/48 , C07D233/96 , C07D261/14 , C07D263/38 , C07D263/44
Abstract: The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of fibrosis and fibrosis-related conditions.
-
-
-
-
-
-
-
-
-