公开(公告)号：US20060177350A1

公开(公告)日：2006-08-10

申请号：US10549284

申请日：2004-03-19

申请人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Iida ,  Hisao Kawaura ,  Noriyuki Iguchi ,  Wataru Hattori ,  Hiroko Someya

发明人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Iida ,  Hisao Kawaura ,  Noriyuki Iguchi ,  Wataru Hattori ,  Hiroko Someya

IPC分类号： G01N1/10

CPC分类号： B01D57/02 ,  B01L3/502707 ,  B01L3/502746 ,  B01L3/502753 ,  B01L3/502784 ,  B01L2200/0668 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/0415 ,  B01L2400/0454 ,  G01N1/40 ,  G01N27/44743 ,  G01N35/08

摘要： A sample-carrier complex (119) is introduced into a sample introducing portion (107), and the sample-carrier complex (119) is moved and deposited on a damming portion (111). The damming portion (111) is heated at a stage in which the predetermined amount of sample-carrier complex (119) is deposited on the damming portion (111). A temperature is increased to a predetermined temperature to break down the sample-carrier complex (119) into a sample (121) and a carrier (123). A voltage is applied between the sample introducing portion (107) and a sample recovery portion (109) to cause the sample (121) to pass through a gap between columnar bodies (115) and move into a second channel (106) to perform predetermined separation and analysis or recovery operation.

摘要翻译： 将样本 - 载体复合体（119）引入到样本引入部分（107）中，并且样本 - 载体复合体（119）移动并沉积在阻挡部分（111）上。 阻挡部分（111）在预定量的样品载体复合物（119）沉积在阻挡部分（111）上的阶段被加热。 将温度升高到预定温度以将样品 - 载体复合物（119）分解成样品（121）和载体（123）。 在样品导入部（107）和样品回收部（109）之间施加电压使样品（121）通过柱状体（115）之间的间隙并移动到第二通道（106）中，以进行预定的 分离和分析或恢复操作。

公开(公告)号：US20060000772A1

公开(公告)日：2006-01-05

申请号：US10536798

申请日：2003-11-28

申请人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Iida ,  Hisa Kawaura ,  Noriyuki Iguchi ,  Hiroko Someya ,  Minoru Asogawa

发明人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Iida ,  Hisa Kawaura ,  Noriyuki Iguchi ,  Hiroko Someya ,  Minoru Asogawa

IPC分类号： B01D15/08

CPC分类号： B01D67/0062 ,  B01D69/00 ,  B01D69/141 ,  B01D71/027 ,  B01L3/502707 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2200/0631 ,  B01L2300/0816 ,  G01N1/34 ,  G01N1/405

摘要： A channel (103) is formed in a substrate (101), and a portion of the channel (103) is provided with a separating portion (107). A number of pillars are formed in the separating portion (107), and an adsorptive substance layer having an adsorptive substance, which exhibits a specific interaction for a specific substance, immobilized on the surface thereof, is formed. Once a sample is introduced into the channel (103), the specific substance is adsorbed on the adsorptive substance layer to be separated from other components. After washing the inside of the channel (103) with a buffer solution, the specific substance is desorbed from the adsorptive substance layer by flowing a eluting solution through the channel (103) and the specific substance is recovered.

摘要翻译： 通道（103）形成在基板（101）中，并且通道（103）的一部分设置有分离部分（107）。 在分离部（107）中形成有多个支柱，并且形成了具有固定在其表面上的特定物质的特定相互作用的具有吸附物质的吸附物质层。 一旦将样品引入通道（103）中，特定物质被吸附在吸附物质层上以与其它组分分离。 用缓冲溶液洗涤通道（103）的内部后，通过使通道（103）流过洗脱液，将特定物质从吸附物质层解吸，回收特定物质。

公开(公告)号：US06881315B2

公开(公告)日：2005-04-19

申请号：US10207852

申请日：2002-07-31

申请人： Kazuhiro Iida ,  Hisao Kawaura ,  Masakazu Baba ,  Toshitsugu Sakamoto ,  Toru Sano ,  Noriyuki Iguchi

发明人： Kazuhiro Iida ,  Hisao Kawaura ,  Masakazu Baba ,  Toshitsugu Sakamoto ,  Toru Sano ,  Noriyuki Iguchi

IPC分类号： B01L99/00 ,  B01L3/00 ,  G01N15/10 ,  G01N15/14 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  C07K1/26

CPC分类号： B01L3/502761 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2400/086 ,  G01N27/44704 ,  G01N27/44773 ,  G01N30/02 ,  G01N30/6052 ,  G01N2030/285 ,  B01D15/34

摘要： A fractionating apparatus is used for fractionating sample into micro-structures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating unit, and pillar patches are formed in the groove at intervals wider than the gap among the pillar patches; while the sample is migrated through the fractionating passage, small-sized DNA molecules are trapped in the pillar patches, and large-sized DNA molecules are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules reaches the end of the fractionating passage faster than the small-sized DNA molecules without clogging.

摘要翻译： 分馏装置用于将样品分级成尺寸不同的微结构，并且包括由分馏通道形成的分馏单元; 分馏通道限定在形成在分馏单元的基板中的槽中，并且在凹槽中以比柱状体之间的间隙宽的间隔形成柱贴片; 当样品通过分馏通道迁移时，小尺寸的DNA分子被捕获在柱状贴片中，大尺寸的DNA分子通过宽间隔平滑地迁移; 这导致大尺寸DNA分子比小尺寸DNA分子更快地到达分级通道的末端而没有堵塞。

公开(公告)号：US06235407B1

公开(公告)日：2001-05-22

申请号：US09194130

申请日：1998-11-23

申请人： Hiroyuki Ogata ,  Sachiko Suzuki ,  Kazuo Mochizuki ,  Takashi Isogai ,  Shigeru Usuda ,  Toru Sano

发明人： Hiroyuki Ogata ,  Sachiko Suzuki ,  Kazuo Mochizuki ,  Takashi Isogai ,  Shigeru Usuda ,  Toru Sano

IPC分类号： B32B1508

CPC分类号： B05D7/51 ,  B05D7/14 ,  B32B15/08 ,  B60K15/03 ,  C23C28/00 ,  Y10T428/12014 ,  Y10T428/12063 ,  Y10T428/12111 ,  Y10T428/12569 ,  Y10T428/12597 ,  Y10T428/12736 ,  Y10T428/12757 ,  Y10T428/1355 ,  Y10T428/31678

摘要： A highly corrosion resistant steel sheet for fuel tank comprising a lowermost layer of Zn or Zn-based plating layer deposited on each side of the steel sheet; a chemical conversion film deposited on each of the Zn or Zn-based plating layer; a metal powder-containing organic resin film deposited on one of the chemical conversion film, said metal powder-containing organic resin film containing Al and Ni metal powders and an amine modified epoxy resin; and a silica-containing organic resin film deposited on the other chemical conversion film, said silica-containing organic resin film containing at least one resin having at least one functional group selected from hydroxyl group, isocyanate group, carboxyl group, glycidyl group, and amino group; silica; and a lubricant. The steel sheet of the present invention has excellent corrosion resistance, press workability, resistance weldability and brazing ability, and therefore, the steel sheet of the present invention is particularly useful when it is used in contact with an alcohol or an alcohol-blended gasoline.

摘要翻译： 一种用于燃料箱的高耐腐蚀钢板，包括沉积在钢板两侧的最下层的Zn或Zn基镀层; 沉积在每个Zn或Zn基镀层上的化学转化膜; 沉积在化学转化膜之一上的含金属粉末的有机树脂膜，含有Al和Ni金属粉末的所述含金属粉末的有机树脂膜和胺改性环氧树脂; 和沉积在另一化学转化膜上的含二氧化硅的有机树脂膜，所述含二氧化硅的有机树脂膜含有至少一种具有至少一个选自羟基，异氰酸酯基，羧基，缩水甘油基和氨基的官能团的树脂 组; 二氧化硅 和润滑剂。 本发明的钢板具有优异的耐腐蚀性，冲压加工性，电阻可焊性和钎焊性，因此本发明的钢板在与醇或醇混汽油接触时特别有用。

公开(公告)号：US5756277A

公开(公告)日：1998-05-26

申请号：US580188

申请日：1995-12-28

申请人： Toru Sano

发明人： Toru Sano

IPC分类号： G03C1/015 ,  G03C1/005 ,  G03C1/035 ,  G03C1/07

CPC分类号： G03C1/0053 ,  G03C1/07

摘要： A method for producing a silver halide emulsion comprising high silver chloride tabular grains each having a chloride content of 50 mol % or more and having a major plane comprising a (111) face, which comprises a step for conducting nucleation of said grains substantially in the absence of a crystal phase controlling agent to form grains which have two twin planes parallel with each other and of which most of the surface are (100) faces, a step for ripening said grains by adding a crystal phase controlling agent which adsorbs to the (111) face or a mixture of a crystal phase controlling agent which adsorbs to the (111) face and a protective colloid to reduce the ratio of grains other than the grains having two or more parallel twin planes and then a step for growing with remaining tabular grains having a major plane mainly comprising a (111) face to form tabular grains having a major plane comprising a (111) face.

摘要翻译： 一种卤化银乳剂的制造方法，其包含高氯化银片状颗粒，其各自具有50摩尔％以上的氯含量，并且具有包括（111）面的主面，其包括基本上在 不存在结晶相控制剂以形成具有彼此平行的两个平面并且其中大部分表面为（100）面的晶粒的晶粒;通过添加吸附至（100）表面的晶体相控制剂来成熟所述晶粒的步骤， 111）面或吸附到（111）面的结晶相控制剂和保护胶体的混合物，以降低具有两个或更多个平行双面的颗粒之外的晶粒的比例，然后是用剩余的片状生长的步骤 具有主要包括（111）面的主平面的颗粒形成具有包括（111）面的主平面的片状颗粒。

公开(公告)号：US07825375B2

公开(公告)日：2010-11-02

申请号：US12092357

申请日：2006-11-09

申请人： Toru Sano

发明人： Toru Sano

IPC分类号： H01J49/00

CPC分类号： H01J49/0418 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/0642 ,  B01L2200/10 ,  B01L2300/0819 ,  G01N33/6851 ,  H01J49/0009

摘要： A microchip 100 is employed as target board of mass spectrometry. The microchip 100 includes a substrate 120, a plurality of sample-distributing sections, provided in the substrate 120 and contains samples that serve as a target of a mass spectrometry distributed therein, and a reference material-supplying channel provided in the substrate 120 and capable of being supplied with a reference material in the mass spectrometry. The plurality of sample-distributing sections are provided in the lateral side of the fine channel 102 for distributing the reference material along the fine channel 102 for distributing the reference material.

摘要翻译： 使用微芯片100作为质谱的靶板。 微芯片100包括基板120，多个样品分配部，设置在基板120中，并且包含用作分布在其中的质谱的靶的样品和设置在基板120中的参考材料供给通道，并且能够 在质谱中提供参考物质。 多个样品分配部分设置在细通道102的横向侧，用于沿着用于分配参考材料的细通道102分配参考材料。

公开(公告)号：US20080070283A1

公开(公告)日：2008-03-20

申请号：US11854315

申请日：2007-09-12

申请人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Ilda ,  Hisao Kawaura ,  Noriyuki Iguchi ,  Wataru Hattori ,  Hiroko Someya

发明人： Toru Sano ,  Masakazu Baba ,  Kazuhiro Ilda ,  Hisao Kawaura ,  Noriyuki Iguchi ,  Wataru Hattori ,  Hiroko Someya

IPC分类号： C12P19/34 ,  C12M1/00

CPC分类号： G01N33/54366 ,  C12Q1/686 ,  C12Q2565/518 ,  C12Q2523/307

摘要： A reaction apparatus (10) includes a substrate (12) and a plurality of columnar members (14) formed on the substrate (12). Oligonucleotides for immobilization (16) having sequences complementary to sequences of both ends of a starting template DNA (18) is adhered on the surfaces of the substrate (12) and the columnar members (14). The starting template DNA (18) can be immobilized over the adjacent columnar members (14) by introducing the starting template DNA (18) under the elongated condition. PCR is conducted in such condition.

摘要翻译： 反应装置（10）包括基板（12）和形成在基板（12）上的多个柱状部件（14）。 具有与起始模板DNA（18）两端的序列互补的序列的固定化寡核苷酸（16）粘附在基材（12）和柱状构件（14）的表面上。 通过在细长条件下引入起始模板DNA（18），起始模板DNA（18）可以固定在相邻的柱状构件（14）上。 PCR在这种条件下进行。

公开(公告)号：US20060214101A1

公开(公告)日：2006-09-28

申请号：US10549587

申请日：2004-03-15

申请人： Katsutoshi Takahashi ,  Kazuhiro Iida ,  Masakazu Baba ,  Noriyuki Iguchi ,  Toru Sano ,  Hisao Kawaura ,  Toshitsugu Sakamoto ,  Wataru Hattori ,  Hiroko Someya

发明人： Katsutoshi Takahashi ,  Kazuhiro Iida ,  Masakazu Baba ,  Noriyuki Iguchi ,  Toru Sano ,  Hisao Kawaura ,  Toshitsugu Sakamoto ,  Wataru Hattori ,  Hiroko Someya

IPC分类号： H01J49/00 ,  B01D59/44

CPC分类号： H01J49/0418 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2200/0663 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/16 ,  B01L2400/086 ,  G01N1/22 ,  G01N30/84 ,  G01N2030/8452

摘要： After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separated in the channel. The ionized fraction is detected by a mass spectrometry unit (363) and analyzed by an analytical result analyzing unit (371). The analytical result is stored in a memory (369) while associated with position information in a driver control unit (367) and information on laser beam irradiation condition in a laser control unit (373), and the analytical result is imaged by an imaging unit (375). The imaged analytical result is displayed on a display (377).

摘要翻译： 在将样品预先分离成在微芯片（353）中形成的通道中的多个部件之后，通过激光振荡器（361）的激光束沿着分离方向照射通道，以顺序地电离通道中分离的每个部分。 通过质谱分析单元（363）检测离子化部分，并通过分析结果分析单元（371）进行分析。 分析结果与激光控制单元（373）中的驱动器控制单元（367）中的位置信息和激光束照射条件的信息相关联地存储在存储器（369）中，并且分析结果由成像单元 （375）。 成像分析结果显示在显示器上（377）。

公开(公告)号：US20060035386A1

公开(公告)日：2006-02-16

申请号：US10537292

申请日：2003-11-25

申请人： Wataru Hattori ,  Masakazu Baba ,  Toru Sano ,  Kazuhiro Iida ,  Hisao Kawaura ,  Hiroko Someya

发明人： Wataru Hattori ,  Masakazu Baba ,  Toru Sano ,  Kazuhiro Iida ,  Hisao Kawaura ,  Hiroko Someya

IPC分类号： G01N33/558

CPC分类号： B01D61/18 ,  B01D29/00 ,  B01D67/0062 ,  B01D69/00 ,  B01D71/02 ,  B01D71/027 ,  B01L3/502746 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2300/0816 ,  B01L2400/086 ,  G01N33/5302

摘要： A channel (1) formed in a substrate (41) branches into channels (2, 3) at a branch point (43). On this branch point, obstacles (8) having a columnar structure are aligned at certain intervals.

摘要翻译： 形成在基板（41）中的通道（1）在分支点（43）处分支成通道（2,3）。 在该分支点上，具有柱状结构的障碍物（8）以一定间隔对准。

公开(公告)号：US20140193052A1

公开(公告)日：2014-07-10

申请号：US14239801

申请日：2012-08-22

申请人： Yoshiko Yoshihara ,  Tomoharu Kiyuan ,  Toru Sano ,  Kenichi Kamijo

发明人： Yoshiko Yoshihara ,  Tomoharu Kiyuan ,  Toru Sano ,  Kenichi Kamijo

IPC分类号： G06T7/00

CPC分类号： G06T7/0012 ,  G01N33/4833 ,  G06F19/321 ,  G06K9/0014 ,  G06K9/6253 ,  G06T2207/10056 ,  G06T2207/30024

摘要： Disclosed is an information processing apparatus that supports diagnosis based on a tissue sample image obtained from imaging a biological tissue, including: a tissue sample image cutting unit that individually cuts out the tissue sample image from a plurality of slides that includes the plurality of tissue sample images; and a display position setting unit that sets a display position on a display screen where a reduced image of each tissue sample image is displayed, on the basis of a characteristic amount of each tissue sample image cut by the tissue sample image cutting unit.

摘要翻译： 公开了一种信息处理设备，其基于从生物组织成像获得的组织样本图像来支持诊断，所述信息处理设备包括：组织样本图像切割单元，其从包括所述多个组织样本的多个幻灯片中单独地切出组织样本图像 图片; 以及显示位置设定单元，其基于由组织样本图像切割单元切割的每个组织样本图像的特征量，在显示屏幕上设置显示每个组织样本图像的缩小图像的显示位置。