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    Anti-infective central venous catheter with diffusion barrier layer
    1.
    发明授权
    Anti-infective central venous catheter with diffusion barrier layer 有权
    具有扩散阻隔层的抗感染性中心静脉导管

    公开(公告)号：US07896852B2

    公开(公告)日：2011-03-01

    申请号：US11170235

    申请日：2005-06-28

    申请人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

    发明人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0017

    摘要： A catheter extending from a distal end which, when in an operative position is inserted within a body of a patient, to a proximal end, the catheter comprising a charge holding cavity to which a therapeutic compound is to be supplied and a wall including inner and outer portions, an inner surface of the inner portion surrounding the charge holding cavity with an outer portion surrounding at least a portion of an outer surface of the inner portion, wherein the inner portion is formed so that a first diffusion rate of the therapeutic compound therethrough is different from a second diffusion rate through the outer portion.

    摘要翻译： 从远端延伸的导管，其在操作位置被插入到患者的身体内时到达近端，所述导管包括电荷保持腔，供给治疗化合物的导管和包括内部和/ 所述内部部分的内表面围绕所述电荷保持腔，外部包围所述内部部分的外表面的至少一部分，其中所述内部部分形成为使得所述治疗化合物通过其中的第一扩散速率 与通过外部的第二扩散速度不同。

    Medical device having anti-microbial properties and a false lumen and method of making the same
    2.
    发明授权
    Medical device having anti-microbial properties and a false lumen and method of making the same 有权
    具有抗菌性和假腔的医疗装置及其制造方法

    公开(公告)号：US07635358B2

    公开(公告)日：2009-12-22

    申请号：US10688224

    申请日：2003-10-15

    申请人： Sharon Mi Lyn Tan

    发明人： Sharon Mi Lyn Tan

    IPC分类号： A61M5/32

    CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/106 ,  A61L2300/404 ,  A61M25/0017

    摘要： A medical device with anti-microbial properties to prevent infections. This medical device, such as an in-dwelling catheter, has a portion that is insertable into the body of a patient and accessible from outside the body once the portion is inserted. The portion has an outer wall, a first active lumen within the outer wall, and a false lumen within the outer wall in which the false lumen has a distal portion and a proximal portion. The false lumen contains an anti-microbial agent that provides the outer wall with anti-microbial properties. The distal portion of the false lumen is sealed. The false lumen may be adjacent to the first active lumen. The medical device may also contain a second active lumen, wherein the first active lumen is an inlet lumen and the second active lumen is an outlet lumen. Alternatively, the false lumen may surround the first active lumen.

    摘要翻译： 具有抗微生物特性的医疗器械，以防止感染。 这种医疗装置，例如住宅导管，具有可插入患者体内的部分，一旦该部分被插入，该部分可从外部进入身体。 该部分具有外壁，外壁内的第一活动内腔和外壁内的假腔，其中假腔具有远侧部分和近端部分。 假腔含有抗微生物剂，为外壁提供抗微生物特性。 假腔的远端被密封。 假腔可以与第一活动管腔相邻。 医疗装置还可以包含第二活动腔，其中第一活动腔是入口腔，而第二活动腔是出口腔。 或者，假腔可围绕第一活动腔。

    System for providing a medical device with anti-microbial properties
    6.
    发明授权
    System for providing a medical device with anti-microbial properties 有权
    提供具有抗微生物性质的医疗器械的系统

    公开(公告)号：US07195615B2

    公开(公告)日：2007-03-27

    申请号：US10438063

    申请日：2003-05-14

    申请人： Sharon Mi Lyn Tan

    发明人： Sharon Mi Lyn Tan

    IPC分类号： A61M5/00

    CPC分类号： A61L29/16 ,  A61L2/16 ,  A61L2300/106 ,  A61L2300/404

    摘要： A system for providing medical device with anti-microbial properties to prevent infections. The system includes a medical device having a portion for insertion into the body of a patient, a lumen, and a substrate comprising an anti-microbial agent to be inserted into the lumen of the medical device. To protect the substrate from anti-microbial agents during insertion into the lumen, the system further includes a collapsible cover connected to the substrate. A connector can be used for attaching the substrate to the cover. The substrate may be an iodine-based rod. A guidewire may be attached to the connector to further facilitate insertion of the substrate into the lumen.

    摘要翻译： 一种用于提供具有抗微生物特性以防止感染的医疗装置的系统。 该系统包括具有用于插入患者体内的部分，内腔和包含要插入医疗装置的内腔中的抗微生物剂的基底的医疗装置。 为了在插入内腔期间保护基底免受抗微生物剂的影响，系统还包括连接到基底的可折叠盖。 可以使用连接器将基板连接到盖上。 基底可以是碘基棒。 导丝可以附接到连接器以进一步便于将基底插入管腔中。

    LATEX MEDICAL ARTICLES FOR RELEASE OF ANTIMICROBIAL AGENTS
    7.
    发明申请
    LATEX MEDICAL ARTICLES FOR RELEASE OF ANTIMICROBIAL AGENTS 审中-公开
    用于释放抗菌药物的LATEX医疗文章

    公开(公告)号：US20110125093A1

    公开(公告)日：2011-05-26

    申请号：US13021018

    申请日：2011-02-04

    申请人： Sharon Mi Lyn Tan

    发明人： Sharon Mi Lyn Tan

    IPC分类号： A61L29/14 ,  A61K47/32 ,  A61K9/00 ,  A61K9/14 ,  A61K33/38 ,  A61P31/00 ,  B05D1/18

    CPC分类号： A61L29/16 ,  A61L29/042 ,  A61L31/049 ,  A61L31/16 ,  A61L2300/10 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/622

    摘要： According to an aspect of the present invention, a medical article is provided which comprises a latex antimicrobial region. The latex antimicrobial region can constitute the entirety of the medical article, or it can constitute only a portion of the medical article. The latex antimicrobial region comprises release-modulating microparticles, which are dispersed within a latex polymer. The release-modulating microparticles further comprise an antimicrobial agent, and the microparticles are adapted to release the antimicrobial agent. Examples of medical articles that can be produced in accordance with the present invention are gloves, finger cots, supply and drainage tubes, catheters, condoms, and contraceptive diaphragms. Also described are methods for forming such articles.

    摘要翻译： 根据本发明的一个方面，提供一种包含胶乳抗微生物区域的医疗制品。 胶乳抗微生物区域可以构成整个医疗制品，或者它可以构成医疗用品的一部分。 胶乳抗微生物区域包含分散在胶乳聚合物中的释放调节微粒。 释放调节微粒还包含抗微生物剂，并且微粒适于释放抗微生物剂。 根据本发明可以生产的医疗制品的实例是手套，手指套，供排水管，导管，避孕套和避孕膜。 还描述了形成这种制品的方法。

    Anti-infective central venous catheter with diffusion barrier layer
    8.
    发明授权
    Anti-infective central venous catheter with diffusion barrier layer 有权
    具有扩散阻隔层的抗感染性中心静脉导管

    公开(公告)号：US07947031B2

    公开(公告)日：2011-05-24

    申请号：US11642453

    申请日：2006-12-19

    申请人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

    发明人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0017

    摘要： A catheter includes a wall surrounding a lumen. The wall has an inner portion forming an outer surface of the lumen and an outer portion surrounding at least a portion of an outer surface of the inner portion. A first diffusion rate of materials from the lumen through the inner portion is different from a second diffusion rate through the outer portion. A durometer hardness of the inner portion is lower than a durometer hardness of the outer portion.

    摘要翻译： 导管包括围绕管腔的壁。 壁具有形成内腔的外表面的内部部分和围绕内部部分的外表面的至少一部分的外部部分。 从内腔到内部的材料的第一扩散速率不同于通过外部的第二扩散速率。 内部部分的硬度计硬度低于外部部分的硬度计硬度。

    Latex medical articles for release of antimicrobial agents
    9.
    发明授权
    Latex medical articles for release of antimicrobial agents 有权
    用于释放抗菌剂的乳胶医药制品

    公开(公告)号：US07906148B2

    公开(公告)日：2011-03-15

    申请号：US10631871

    申请日：2003-07-31

    申请人： Sharon Mi Lyn Tan

    发明人： Sharon Mi Lyn Tan

    IPC分类号： A61K9/50

    CPC分类号： A61L29/16 ,  A61L29/042 ,  A61L31/049 ,  A61L31/16 ,  A61L2300/10 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/622

    摘要： According to an aspect of the present invention, a medical article is provided which comprises a latex antimicrobial region. The latex antimicrobial region can constitute the entirety of the medical article, or it can constitute only a portion of the medical article. The latex antimicrobial region comprises release-modulating microparticles, which are dispersed within a latex polymer. The release-modulating microparticles further comprise an antimicrobial agent, and the microparticles are adapted to release the antimicrobial agent. Examples of medical articles that can be produced in accordance with the present invention are gloves, finger cots, supply and drainage tubes, catheters, condoms, and contraceptive diaphragms. Also described are methods for forming such articles.

    摘要翻译： 根据本发明的一个方面，提供一种包含胶乳抗微生物区域的医疗用品。 胶乳抗微生物区域可以构成整个医疗制品，或者它可以构成医疗用品的一部分。 胶乳抗微生物区域包含分散在胶乳聚合物中的释放调节微粒。 释放调节微粒还包含抗微生物剂，并且微粒适于释放抗微生物剂。 可以根据本发明生产的医疗制品的实例是手套，手指套，供排水管，导管，避孕套和避孕膜。 还描述了形成这种制品的方法。