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公开(公告)号：US20110011781A1
公开(公告)日：2011-01-20
申请号：US12867335
申请日：2009-02-26
Applicant: Gert Blankenstein , Holger Bartos , Ralf-Peter Peters , Christian Schoen
Inventor： Gert Blankenstein , Holger Bartos , Ralf-Peter Peters , Christian Schoen
CPC classification number: B01L3/502753 , B01D29/014 , B01D29/05 , B01D61/18 , B01D63/08 , B01D63/087 , B01D63/088 , B01D2201/0415 , B01D2201/44 , B01L3/502715 , B01L2300/0681 , B01L2300/0864 , B01L2400/0406 , G01N33/491
Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.
Abstract translation: 本发明涉及一种用于分离血液的装置，更具体地说，涉及用于吸收血液（19）并分离血液成分的装置（1）。 血浆，作为样品液体（2）。 所述装置（1）包括用于吸收血液（2）的供给装置（13），用于分离作为样品液体（2）的血液成分的装置（15），优选地通过以下方式吸收样品液体 以及用于在管道（3）的入口或进料区（18）中用样品液体（2）填充管道（3）的装置。 分离装置（15），特别是膜是弯曲的，特别是凸形的，并且所述弯曲的，特别是凸形的顶点突出到填充装置中。
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公开(公告)号：US20050155415A1
公开(公告)日：2005-07-21
申请号：US11014192
申请日：2004-12-17
Applicant: Dirk Kurowski , Christian Schoen , Ralf-Peter Peters , Holger Bartos , Ying Yu
Inventor： Dirk Kurowski , Christian Schoen , Ralf-Peter Peters , Holger Bartos , Ying Yu
IPC: A61B5/00 , C12Q1/56 , G01N11/10 , G01N11/16 , G01N27/74 , G01N33/487 , G01N33/49 , G01N33/66 , G01N33/86 , G01N11/00
CPC classification number: G01N11/162 , A61B5/14532 , C12Q1/56 , G01N11/10 , G01N27/3271 , G01N33/4905 , G01N33/66 , G01N2011/0086
Abstract: A process and a device for determining the viscosity of a fluid are proposed. Very simple and accurate determination is enabled in that the magnetic particles in the fluid are set into vibration by a magnetic field which varies over time. A measurement of the amplitude and/or phase of particle vibration is used to determine the viscosity or an associated quantity, such as the coagulation of blood or the glucose content.
Abstract translation: 提出了一种用于确定流体粘度的方法和装置。 通过随时间变化的磁场将流体中的磁性颗粒设定为振动，能够进行非常简单且准确的测定。 使用粒子振动的振幅和/或相位的测量来确定粘度或相关量，例如血液凝结或葡萄糖含量。
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公开(公告)号：US09539572B2
公开(公告)日：2017-01-10
申请号：US12867335
申请日：2009-02-26
Applicant: Gert Blankenstein , Holger Bartos , Ralf-Peter Peters , Christian Schoen
Inventor： Gert Blankenstein , Holger Bartos , Ralf-Peter Peters , Christian Schoen
CPC classification number: B01L3/502753 , B01D29/014 , B01D29/05 , B01D61/18 , B01D63/08 , B01D63/087 , B01D63/088 , B01D2201/0415 , B01D2201/44 , B01L3/502715 , B01L2300/0681 , B01L2300/0864 , B01L2400/0406 , G01N33/491
Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.
Abstract translation: 本发明涉及一种用于分离血液的装置，更具体地说，涉及用于吸收血液（19）并分离血液成分的装置（1）。 血浆，作为样品液体（2）。 所述装置（1）包括用于吸收血液（2）的供给装置（13），用于分离作为样品液体（2）的血液成分的装置（15），优选地通过以下方式吸收样品液体 以及用于在管道（3）的入口或进料区（18）中用样品液体（2）填充管道（3）的装置。 分离装置（15），特别是膜是弯曲的，特别是凸形的，并且所述弯曲的，特别是凸形的顶点突出到填充装置中。
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公开(公告)号：US07931868B2
公开(公告)日：2011-04-26
申请号：US10864359
申请日：2004-06-10
Applicant: Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
IPC: B01L3/00 , H01L21/8238
CPC classification number: G01N33/54386 , B01L3/502746 , B01L2200/0668 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/0896 , B01L2400/086 , B82Y30/00
Abstract: Device for manipulation of limited quantities of liquids with the following features: the device has at least one solid; the solid has surface areas in which different capillary forces act; one or more first surface areas have a microstructured and/or nanostructured surface; the microstructured and/or nanostructured surfaces have regularly arranged structure elements (A to E); the solid and the structure elements consist of one material and are connected to one another in one piece; one or more first surface areas are provided with reagents; the second surface area encompasses at least one of the first surface areas.
Abstract translation: 用于操作有限量的液体的装置具有以下特征：该装置具有至少一个固体; 固体具有不同毛细作用作用的表面区域; 一个或多个第一表面区域具有微结构和/或纳米结构化表面; 微结构和/或纳米结构表面具有规则排列的结构元件（A至E）; 固体和结构元件由一种材料组成并且彼此连接成一体; 一个或多个第一表面区域设有试剂; 所述第二表面区域包括所述第一表面区域中的至少一个。
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公开(公告)号：US20050026346A1
公开(公告)日：2005-02-03
申请号：US10864359
申请日：2004-06-10
Applicant: Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
IPC: G01N35/08 , B01J19/00 , B01L3/00 , G01N33/543 , G01N37/00 , H01L21/8238
CPC classification number: G01N33/54386 , B01L3/502746 , B01L2200/0668 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/0896 , B01L2400/086 , B82Y30/00
Abstract: Device for manipulation of limited quantities of liquids with the following features: the device has at least one solid; the solid has surface areas in which different capillary forces act; one or more first surface areas have a microstructured and/or nanostructured surface; the microstructured and/or nanostructured surfaces have regularly arranged structure elements (A to E); the solid and the structure elements consist of one material and are connected to one another in one piece; one or more first surface areas are provided with reagents; the second surface area encompasses at least one of the first surface areas.
Abstract translation: 用于操作有限量的液体的装置具有以下特征：该装置具有至少一个固体; 固体具有不同毛细作用作用的表面区域; 一个或多个第一表面区域具有微结构和/或纳米结构化表面; 微结构和/或纳米结构表面具有规则排列的结构元件（A至E）; 固体和结构元件由一种材料组成并且彼此连接成一体; 一个或多个第一表面区域设有试剂; 所述第二表面区域包括所述第一表面区域中的至少一个。
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Patent Agency Ranking
6.发明授权Apparatus for precise transfer and manipulation of fluids by centrifugal and or capillary forces 有权用于通过离心和/或毛细作用力精确地转移和操纵流体的装置公开(公告)号：US08337775B2
公开(公告)日：2012-12-25
申请号：US12205965
申请日：2008-09-08
Applicant: Michael J. Pugia , Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Michael J. Pugia , Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
IPC: G01N33/00
CPC classification number: B01L3/5025 , B01L3/5027 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L2200/0605 , B01L2200/10 , B01L2300/0645 , B01L2300/0861 , B01L2300/165 , B01L2400/0406 , B01L2400/06 , B01L2400/0688 , F04B19/006 , Y10T436/2575
Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.
Abstract translation: 在使用离心和毛细管力的装置中分析微升液体样品，特别是生物样品。 通过互连的毛细管通道将样品移动通过一个或多个排列在小扁平芯片内的样品阱。 通道可以是疏水的或亲水的，并且可以包括疏水或亲水的毛细管停止。
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公开(公告)号：US08318110B2
公开(公告)日：2012-11-27
申请号：US13047330
申请日：2011-03-14
Applicant: Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
CPC classification number: G01N33/54386 , B01L3/502746 , B01L2200/0668 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/0896 , B01L2400/086 , B82Y30/00
Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.
Abstract translation: 用于在激光单元的激光光源的前面配置至少一个光学部件的保持装置，包括：第一保持部，至少一个光学部件被附接到该第一保持部，所述保持装置还包括附接的第二保持部 到所述激光单元的一部分，并且所述第一保持部附接到所述第二保持部。 此外，本发明涉及具有这种保持装置的装置和用于产生该装置的方法。
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公开(公告)号：US20110172109A1
公开(公告)日：2011-07-14
申请号：US13047330
申请日：2011-03-14
Applicant: Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
CPC classification number: G01N33/54386 , B01L3/502746 , B01L2200/0668 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/0896 , B01L2400/086 , B82Y30/00
Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.
Abstract translation: 用于在激光单元的激光光源的前面配置至少一个光学部件的保持装置，包括：第一保持部，至少一个光学部件被附接到该第一保持部，所述保持装置还包括附接的第二保持部 到所述激光单元的一部分，并且所述第一保持部附接到所述第二保持部。 此外，本发明涉及具有这种保持装置的装置和用于产生该装置的方法。
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9.发明申请公开(公告)号：US20110088786A1
公开(公告)日：2011-04-21
申请号：US12977516
申请日：2010-12-23
Applicant: Gert BLANKENSTEIN , Thomas Willms , Ralf-Peter Peters , Claus Marquordt , Holger Bartos
Inventor： Gert BLANKENSTEIN , Thomas Willms , Ralf-Peter Peters , Claus Marquordt , Holger Bartos
IPC: F15D1/00
CPC classification number: F16K99/0001 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0605 , B01L2200/0621 , B01L2200/0684 , B01L2300/069 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0688 , F16K99/0017 , F16K99/0057 , F16K2099/0074 , F16K2099/0084 , Y10T137/0318 , Y10T137/86389
Abstract: A method for manipulating a first liquid within a device including fabricated microstructures for transporting the first liquid through a system of capillary channels and cavities with a closed configuration. The method including transporting the first liquid through the system by capillary force only, stopping a flow of the first liquid temporarily at a capillary stop, switching on the flow of the first liquid after a desired stop time is elapsed, adjusting the stop time of the first liquid by a length and a cross-section of the control capillary between a beginning of the control capillary and its end at the capillary stop, metering the first liquid to be manipulated, and holding a metered amount of the first liquid during the stop time within a cavity.
Abstract translation: 一种用于操纵装置内的第一液体的方法，包括制造的微结构，用于通过具有闭合构型的毛细通道和空腔系统输送第一液体。 该方法包括仅通过毛细管力运送第一液体通过系统，停止毛细管停止时第一液体的流动，在期望的停止时间之后切换第一液体的流动，调整第一液体的停止时间 第一液体在控制毛细管的开始处和毛细管停止之前的控制毛细管的长度和横截面上，计量待操作的第一液体，并在停止时间期间保持计量的第一液体 在一个空腔内
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10.发明授权Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces 有权用于通过离心和/或毛细管力精确地转移和操纵流体的方法和装置公开(公告)号：US07459127B2
公开(公告)日：2008-12-02
申请号：US10082415
申请日：2002-02-26
Applicant: Michael J. Pugia , Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
Inventor： Michael J. Pugia , Gert Blankenstein , Ralf-Peter Peters , Holger Bartos
IPC: G01N33/00
CPC classification number: B01L3/5025 , B01L3/5027 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L2200/0605 , B01L2200/10 , B01L2300/0645 , B01L2300/0861 , B01L2300/165 , B01L2400/0406 , B01L2400/06 , B01L2400/0688 , F04B19/006 , Y10T436/2575
Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.
Abstract translation: 在使用离心和毛细管力的装置中分析微升液体样品，特别是生物样品。 通过互连的毛细管通道将样品移动通过一个或多个排列在小扁平芯片内的样品阱。 通道可以是疏水的或亲水的，并且可以包括疏水或亲水的毛细管停止。
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