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公开(公告)号：US11453872B2
公开(公告)日：2022-09-27
申请号：US15523820
申请日：2015-10-28
发明人： Chung Hong Cheung , Jun Wang , Junming Chen , Guilin Wang
IPC分类号： C12M1/40 , C12M1/00 , C12N11/06 , C12N11/02 , B01J19/22 , C07K1/04 , C07K17/06 , C12M1/12 , C12M1/26
摘要： Provided herein are a device and a method for preparation of immobilized proteins, enzymes or cells on a carrier to achieve the industrial batch production of the immobilized proteins, enzymes or cells.
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公开(公告)号：US20220389401A1
公开(公告)日：2022-12-08
申请号：US17820638
申请日：2022-08-18
发明人： Chung Hong Cheung , Jun Wang , Junming Chen , Guilin Wang
IPC分类号： C12N11/06 , C12M1/40 , C12M1/00 , C12N11/02 , B01J19/22 , C07K1/04 , C07K17/06 , C12M1/12 , C12M1/26
摘要： Provided herein are a device and a method for preparation of immobilized proteins, enzymes or cells on a carrier to achieve the industrial batch production of the immobilized proteins, enzymes or cells.
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公开(公告)号：US20240173239A1
公开(公告)日：2024-05-30
申请号：US17792977
申请日：2022-01-28
发明人： Jun Wang , Wing Keung Poon , Kam Chun Lo
CPC分类号： A61K8/675 , A23G4/126 , A61K8/042 , A61K8/66 , A61K8/671 , A61K8/676 , A61Q11/00 , A61K2800/5922 , A61K2800/92
摘要： Provided herein are an oral care additive, an oral care composition, a method of preparing the same, an oral care kit and use thereof. The main ingredient of the oral care additive contains one or more of nicotinic acid, nicotinamide or derivatives thereof to supplement and increase the level of β-nicotinamide adenine dinucleotide in the oral cavity, and various vitamin and coenzyme may be included as well to complement the function of the main ingredient. The additives and the application methods of the present invention retain the functionality of the existing oral care products while adding new efficacy, thereby providing a more comprehensive oral health management experience for the user.
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4.发明公开公开(公告)号：US20230392136A1
公开(公告)日：2023-12-07
申请号：US18272347
申请日：2021-11-12
发明人： Chung Hong CHEUNG , Jun WANG
CPC分类号： C12N11/10 , C12N1/20 , C12N9/92 , C12Y503/01018 , C12N2533/72 , C12N2537/10
摘要： A membranous immobilized cell, polypeptide, oligopeptide or protein and a preparation method thereof are provided. The method includes the following steps: 1) providing un-film-form chitosan, where the chitosan is un-pre-crosslinked or pre-crosslinked; 2) providing a mixture of the un-film-form chitosan and cell, polypeptide, oligopeptide or protein, and in the mixture, the un-film-form chitosan is in a dissolved state; 3) mixing the mixture with a crosslinking reagent to obtain a co-crosslinked product of the chitosan and the cell, polypeptide, oligopeptide or protein; and 4) drying the co-crosslinked product to obtain membranous immobilized cell, polypeptide, oligopeptide or protein. When un-pre-crosslinked chitosan is used in the step 1), the method further includes comprises the step 5) mixing the membranous immobilized cell, polypeptide, oligopeptide or protein with phosphate salt, so that chitosan molecules therein are crosslinked with each other.
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公开(公告)号：US20220315905A1
公开(公告)日：2022-10-06
申请号：US17618091
申请日：2020-06-01
发明人： Sup Yin Tsang , Wing Keung Poon , Yau Lung Siu , Kam Chun Lo , Jun Wang
摘要： Provided are an enzymatic reaction composition, a method for increasing the amount of adenosine triphosphate (ATP) in an enzymatic reaction, and a method for synthesizing amino acids or derivatives thereof, polypeptides, enzymes or proteins by using ATP. In the method, a first enzyme or enzyme group for producing adenosine monophosphate (AMP) is added during the enzymatic reaction so as to additionally increase the amount of ATP.
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公开(公告)号：US20200369844A1
公开(公告)日：2020-11-26
申请号：US16989041
申请日：2020-08-10
发明人： Chung Hong Cheung , Jun Wang
IPC分类号： C08J9/00 , C07K17/06 , C07K17/08 , C07K1/22 , C12N11/06 , C12N11/08 , B01D15/38 , C12N11/02 , C07K17/04 , C12N9/10 , B01J20/32 , B01J20/286 , B01J20/26 , B01J20/24 , A01N43/68 , B01J31/02 , B01J31/06 , C07K5/083 , C07K7/62 , C07K14/31 , C12N11/10
摘要： The invention is directed to a complex, including: a porous composite carrier including: a porous organic foam material containing open pores, each pore comprising a wall defining the pore; and a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam materials, and a protein, polypeptide, or oligopeptide immobilized onto the porous composite carrier through a reaction between an amino group of the protein, polypeptide or oligopeptide and an aldehyde group of the composite carrier. The immobilized product has high specific surface area and high specific activity. The immobilization is simple and in low cost, and is suitable for industrial application.
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公开(公告)号：US20170321207A1
公开(公告)日：2017-11-09
申请号：US15523820
申请日：2015-10-28
发明人： Chung Hong Cheung , Jun Wang , Junming Chen , Guilin Wang
CPC分类号： C12N11/06 , B01J19/22 , C07K1/042 , C07K17/06 , C12M21/14 , C12M21/18 , C12M25/00 , C12M29/06 , C12M33/00 , C12N11/02
摘要： Provided herein are a device and a method for preparation of immobilized proteins, enzymes or cells on a carrier to achieve the industrial batch production of the immobilized proteins, enzymes or cells.
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8.发明申请Composite Carrier for Immobilization of Proteins, Polypeptides or Oligopeptides, Preparation Methods and Application Thereof 审中-公开用于固定蛋白质，多肽或寡肽的复合载体，其制备方法和应用公开(公告)号：US20160168347A1
公开(公告)日：2016-06-16
申请号：US14902728
申请日：2014-07-08
发明人： Chung Hong Cheung , Jun Wang
IPC分类号： C08J9/00 , C07K17/06 , C07K7/62 , A01N43/68 , B01J31/06 , C07K5/083 , C07K14/31 , C12N11/10 , B01J31/02 , C07K17/08 , C07K1/22
CPC分类号： C08J9/0061 , A01N43/68 , B01D15/3809 , B01J20/24 , B01J20/267 , B01J20/286 , B01J20/3212 , B01J20/3219 , B01J20/3274 , B01J31/0234 , B01J31/06 , C07K1/22 , C07K5/0806 , C07K7/62 , C07K14/31 , C07K17/04 , C07K17/06 , C07K17/08 , C08J2201/026 , C08J2361/28 , C08J2403/10 , C08J2405/08 , C12N9/1051 , C12N11/02 , C12N11/06 , C12N11/08 , C12N11/10
摘要： Provided are a composite carrier for immobilization of a protein, polypeptide or oligopeptide, a preparation method and an application thereof. The composite carrier is a porous material which comprises: (1) a porous organic foam material containing open pores; and (2) a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam material, wherein the aldehyde groups are able to react with the protein, polypeptide or oligopeptide, and the crosslinked product are formed by chitosan via a crosslinking reaction with a polyaldehyde compound.
摘要翻译： 提供用于固定蛋白质，多肽或寡肽的复合载体，其制备方法和应用。 复合载体是多孔材料，其包括：（1）含有开孔的多孔有机泡沫材料; 和（2）具有醛基并且固定在多孔有机泡沫材料的一个或多个孔的壁的表面上的交联产物，其中醛基能够与蛋白质，多肽或寡肽反应，并且交联产物 由壳聚糖通过与多醛化合物的交联反应形成。
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