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公开(公告)号：US20240342063A1
公开(公告)日：2024-10-17
申请号：US18320218
申请日：2023-05-19
发明人： Lixian LI , Kegong NING , Qiuxia ZHANG , Ping LIU , Peng WU , Xiangye KONG , Ying CAI , Feng GAO
CPC分类号： A61K8/24 , A61K8/042 , A61Q11/00 , A61K2800/92
摘要： Disclosed is an amorphous calcium phosphate gel, as well as a preparation method and use thereof. The method comprises: adding aminomethyl propanol to a propylene glycol solution containing a calcium source to obtain a mixture; slowly adding a phosphoric acid solution to the mixture to obtain the amorphous calcium phosphate gel. The amorphous calcium phosphate gel as provided in the present disclosure has an excellent stability, which shows no obvious phase change after being left at room temperature for 12 months. The method avoids the use of toxic and harmful agents, which allows the production process to be safe and environmentally friendly, and also ensures the safety of the product. The method has a simple process, which allows the large-scale production of the product and provides a basis for the wide application of the amorphous calcium phosphate gel in oral care.
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公开(公告)号：US12109299B2
公开(公告)日：2024-10-08
申请号：US17354400
申请日：2021-06-22
发明人： Juliana Carvalhães Lago , Daniela Zimbardi , Carla Maria Sanches Scanavez De Paula , Ana Paula Pedroso De Oliveira , Cintia Rosa Ferrari , Caroline Ziegler Stüker , Juliana Beltrame Reigada , Debora Cristina Castellani
IPC分类号： A61K8/97 , A61K8/92 , A61K36/889 , A61P17/14 , A61Q7/00
CPC分类号： A61K8/922 , A61K36/889 , A61P17/14 , A61Q7/00 , A61K2800/91 , A61K2800/92
摘要： Cosmetic and/or pharmaceutical compositions for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway are provided. The compositions include at least one plant lipid, preferably pataua (Oenocarpus bataua) oil. Also included are methods for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway.
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公开(公告)号：US20240216230A1
公开(公告)日：2024-07-04
申请号：US18396092
申请日：2023-12-26
发明人： Dailin CHEN , Xiao Yi HUANG
CPC分类号： A61K8/0237 , A61K8/25 , A61K8/73 , A61Q11/00 , A61K2800/42 , A61K2800/92
摘要： Oral care compositions having a unique, multicolored pattern, and methods for the same are disclosed. The method for preparing an oral care composition having a unique, multicolored pattern may include forming a matrix in a base oral care composition, contacting a first colorant with a first portion of the base oral care composition, and contacting a second colorant with a second portion of the base oral care composition. The method may also include disposing the first portion of the oral care composition into a vessel via a first nozzle, disposing the second portion of the oral care composition into the vessel via a second nozzle, and forming a unique, multicolored pattern of the first and second colorants in the vessel.
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公开(公告)号：US12023388B2
公开(公告)日：2024-07-02
申请号：US17228039
申请日：2021-04-12
IPC分类号： A61K49/00 , A61K8/02 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/55 , A61K8/64 , A61K8/72 , A61K8/73 , A61Q11/00
CPC分类号： A61K49/0054 , A61K8/0241 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/55 , A61K8/64 , A61K8/72 , A61K8/732 , A61K8/736 , A61K49/0043 , A61K49/0093 , A61Q11/00 , A61K2800/413 , A61K2800/42 , A61K2800/434 , A61K2800/5426 , A61K2800/57 , A61K2800/654 , A61K2800/81 , A61K2800/92
摘要： Components, for example, nanoparticles for detecting and/or treating one or more active carious lesions or microcavities in teeth of a subject are provided. The component or nanoparticle may comprise a biocompatible and biodegradable polymer (e.g., a starch) bearing at least one cationic region and/or having a net positive charge and thereby capable of associating with one or more active and/or early carious lesions on a tooth in an oral cavity of a subject. The components or nanoparticles are optionally water soluble or dispersible. The components or nanoparticle also comprises an imaging agent (e.g., a fluorophore or dye) bonded to the biocompatible and biodegradable polymer. The component or nanoparticle is thus capable of indicating the presence of one or more active carious lesions when the component or nanoparticle is associated therewith. Oral care compositions comprising such compounds/nanoparticles and methods of making and using the same are also provided.
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公开(公告)号：US20240197578A1
公开(公告)日：2024-06-20
申请号：US18589567
申请日：2024-02-28
发明人： Jeanette Marie Swartz , Arif Ali Baig , Gregory Charles Gordon , Min Mao , Melissa Cherie Payne , Holly Balasubramanian Rauckhorst , Paul Albert Sagel , Paul Dennis Trokhan , Brian Patrick Croll , Dinah Achola Nyangiro
IPC分类号： A61K8/02 , A61K8/04 , A61K8/19 , A61K8/20 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/27 , A61K8/34 , A61K8/36 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/81 , A61Q11/00
CPC分类号： A61K8/0204 , A61K8/046 , A61K8/19 , A61K8/20 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/345 , A61K8/416 , A61K8/442 , A61K8/463 , A61K8/60 , A61K8/8129 , A61Q11/00 , A46B2200/1066 , A61K8/24 , A61K8/347 , A61K8/36 , A61K2800/28 , A61K2800/882 , A61K2800/92 , A61K2800/95
摘要： Oral care compositions and/or unit-dose oral care compositions comprising a high level of surfactant. Oral care compositions and/or unit-dose oral care compositions with a high foaming efficiency. Oral care compositions and/or unit-dose oral care compositions with one or more web forming materials, one or more surfactants, and a sugar alcohol.
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公开(公告)号：US20240180802A1
公开(公告)日：2024-06-06
申请号：US17773058
申请日：2020-10-30
申请人： DEINOVE
CPC分类号： A61K8/31 , A61K31/01 , A61P17/02 , A61Q17/04 , A61K2800/92
摘要： The present invention relates to the use of neurosporene to protect the skin from the harmful effects of blue light and/or UVA, to promote epidermal regeneration or renewal, and to stimulate wound healing.
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公开(公告)号：US20240173239A1
公开(公告)日：2024-05-30
申请号：US17792977
申请日：2022-01-28
发明人： Jun Wang , Wing Keung Poon , Kam Chun Lo
CPC分类号： A61K8/675 , A23G4/126 , A61K8/042 , A61K8/66 , A61K8/671 , A61K8/676 , A61Q11/00 , A61K2800/5922 , A61K2800/92
摘要： Provided herein are an oral care additive, an oral care composition, a method of preparing the same, an oral care kit and use thereof. The main ingredient of the oral care additive contains one or more of nicotinic acid, nicotinamide or derivatives thereof to supplement and increase the level of β-nicotinamide adenine dinucleotide in the oral cavity, and various vitamin and coenzyme may be included as well to complement the function of the main ingredient. The additives and the application methods of the present invention retain the functionality of the existing oral care products while adding new efficacy, thereby providing a more comprehensive oral health management experience for the user.
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公开(公告)号：US20240050344A1
公开(公告)日：2024-02-15
申请号：US18549085
申请日：2021-03-11
发明人： Ying YANG , Shaopeng XU , Guofeng XU , Harsh Mahendra TRIVEDI , James MASTERS , Dandan CHEN , Betty WON
CPC分类号： A61K8/44 , A61K8/27 , A61Q11/00 , A61K8/21 , A61K2800/92
摘要： Methods of increasing sIgA levels in an individual's oral cavity are disclosed. The methods comprise applying effective amounts of zinc oxide, zinc citrate, and arginine Methods of increasing the concentration of sIgA in the individual's mucosa pellicle in the oral cavity are disclosed. Methods of increasing phagocytotic activity of phagocytotic cells in the individual's oral cavity are also disclosed. In addition, methods of increasing levels of β-Defensin 1 in the individual's oral cavity are disclosed.
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公开(公告)号：US11883520B2
公开(公告)日：2024-01-30
申请号：US16899882
申请日：2020-06-12
发明人： Ross Strand , Yang Su , Yunming Shi , Thanigaivel Shanmugam , Guannan Wang , Xiaoxiao Li
CPC分类号： A61K8/735 , A61K8/042 , A61K8/4946 , A61K8/8147 , A61Q11/00 , A61K2800/30 , A61K2800/87 , A61K2800/92
摘要： Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Said leave-on oral care compositions comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer and an additional polymer.
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公开(公告)号：US20240024225A1
公开(公告)日：2024-01-25
申请号：US17869261
申请日：2022-07-20
发明人： Tiandong Jia , Jie Sun , Christine S.t. Ng
IPC分类号： A61K8/9794 , A61Q11/00 , A61K8/02 , A61K8/19 , A61K8/9789 , A61K8/98 , A61K8/73 , A61K8/365 , A61K8/65 , A61K8/66 , A61K8/99 , A23K40/30 , A23K40/25 , A23K50/40 , A23K10/35 , A23K20/163 , A23K20/105 , A23K20/22 , A23K10/18 , A23K20/189 , A23K20/174
CPC分类号： A61K8/9794 , A61Q11/00 , A61K8/0216 , A61K8/19 , A61K8/9789 , A61K8/986 , A61K8/731 , A61K8/365 , A61K8/65 , A61K8/66 , A61K8/99 , A23K40/30 , A23K40/25 , A23K50/40 , A23K10/35 , A23K20/163 , A23K20/105 , A23K20/22 , A23K10/18 , A23K20/189 , A23K20/174 , A61K2800/92
摘要： A pet dental treat includes an outer shell constituting a dense, solid shell which keeps the dog occupied while the dog's teeth sink into a soft, chewy porous inner core, potentially coated on exposed surface(s) such as with a bio-active compound, to scrape tartar and remove plaque from the dog's teeth, including hard-to-reach teeth, thereby helping to maintain the oral health of the dog while also reducing bad breath. The pet dental treat has a cross-section visually resembling a tooth and includes a longitudinal slot defining an integral pocket having in-turned retaining elements at an entrance to the slot, with the pocket provided to selectively retain a functional, edible additive insert, such as a vitamin, medicinal item or the like insert, to be given to the pet, with the retaining elements preventing the edible insert from inadvertently falling out of the pocket.
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