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公开(公告)号：US11883368B2
公开(公告)日：2024-01-30
申请号：US16899919
申请日：2020-06-12
发明人： Ross Strand , Yang Su , Yunming Shi , Xiaoxiao Li , Guannan Wang
IPC分类号： A61K31/728 , A61K31/375 , A61K31/355 , A61K31/197 , A61C19/06 , A61K31/7016 , A61K9/00 , A61K8/73 , A61K8/81 , A61K8/67 , A61K8/60 , A61Q11/00 , A61K47/32
CPC分类号： A61K31/728 , A61C19/063 , A61K8/60 , A61K8/673 , A61K8/676 , A61K8/678 , A61K8/735 , A61K8/8147 , A61K9/0053 , A61K31/197 , A61K31/355 , A61K31/375 , A61K31/7016 , A61K47/32 , A61Q11/00 , A61K2800/00 , A61K2800/30
摘要： Leave-on oral care compositions comprising a hyaluronic acid, and a gum-strengthening polyol are provided for promoting Gum Health of a user.
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公开(公告)号：US20150320654A1
公开(公告)日：2015-11-12
申请号：US14633256
申请日：2015-02-27
发明人： Xiaoxiao Li , Yujun Li , Ross Strand , Xiujun Xu
CPC分类号： A61K8/19 , A61K8/20 , A61K8/73 , A61K8/731 , A61K2800/48 , A61K2800/52 , A61K2800/594 , A61Q11/00
摘要： Oral care composition comprises a stannous ion source and a thickener comprising at least 2 agents selected from the group consisting of: i) a linear sulfated polysaccharide; ii) a natural gum; iii) and a non-ionic cellulose derivative. A method for treating the oral cavity comprises administering to the oral cavity the oral care composition.
摘要翻译： 口腔护理组合物包含亚锡离子源和增稠剂，其包含至少2种选自以下的试剂：i）线性硫酸化多糖; ii）天然胶; iii）和非离子纤维素衍生物。 用于治疗口腔的方法包括向口腔施用口腔护理组合物。
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公开(公告)号：US11813343B2
公开(公告)日：2023-11-14
申请号：US17024824
申请日：2020-09-18
发明人： Ross Strand , Xiaoxiao Li , Yunming Shi
CPC分类号： A61K8/27 , A61K8/19 , A61K8/21 , A61K8/25 , A61K8/44 , A61Q11/00 , A61K2800/30 , A61K2800/48
摘要： Dentifrice compositions comprising zinc ion, glycine and fluoride ion source, especially in the absence of stannous ion source, are provided for treating dental plaque biofilm.
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公开(公告)号：US20140377315A1
公开(公告)日：2014-12-25
申请号：US14312763
申请日：2014-06-24
发明人： Ross Strand , Yujun Li , Yiqun Zhang , Xiaoxiao Li , Hanbo Bao
CPC分类号： A61K8/0275 , A61K8/25 , A61K2800/41 , A61Q11/00
摘要： The present invention provides an oral care composition for encouraging proper tooth cleaning, containing particulate materials which can be breakable under a brushing action with a brushing force from 0.1N to 5N. The particulate materials can have a particle size distribution characterized by (1) a change ratio of mean particle size before and after the brushing action is at least 20%, (2) a change ratio of D90 before and after the brushing action is at least 20%, (3) at least 5% of the particulate materials have a particle size greater than 200 μm before the brushing action, and (4) no more than 30% of the particulate materials have a particle size greater than 200 μm after the brushing action. The oral care composition can have a viscosity ranging from 10 to 90 BKU.
摘要翻译： 本发明提供一种用于鼓励适当的牙齿清洁的口腔护理组合物，其含有在刷洗作用下可以用0.1N至5N的刷洗力破裂的颗粒材料。 颗粒材料可以具有以下特征的粒度分布：（1）刷洗作用前后平均粒径的变化率至少为20％，（2）刷牙作用前后的D90变化率至少为 20％，（3）至少5％的颗粒材料在刷涂作用之前具有大于200μm的粒度，和（4）不超过30％的颗粒材料的颗粒尺寸大于200μm后 刷牙动作。 口腔护理组合物可以具有10至90BKU的粘度。
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公开(公告)号：US20140377188A1
公开(公告)日：2014-12-25
申请号：US14312749
申请日：2014-06-24
发明人： Ross Strand , Yujun Li , Yiqun Zhang , Xiaoxiao Li , Zhong Lei
CPC分类号： A61K8/0275 , A61K8/25 , A61K2800/41 , A61Q11/00
摘要： The present invention provides an oral care composition, containing at least 0.5% by weight of silica agglomerates, wherein each of the silica agglomerates has: (i) an overall particle size from 200 μm to 2000 μm, and (ii) a crush strength from 0.1N to 5N. The silica particles that make up the silica agglomerate can have an average particle size from 1 μm to 50 μm. The composition can have a viscosity from 10 to 90 BKU. The present invention also provides a method of encouraging proper tooth cleaning by administering the oral care composition of the present invention to a subject's tooth surface. The present invention further provides the use of a silica agglomerate in manufacturing an oral care composition for encouraging proper tooth cleaning
摘要翻译： 本发明提供了含有至少0.5重量％的二氧化硅附聚物的口腔护理组合物，其中每个二氧化硅附聚物具有：（i）总体粒径为200μm至2000μm，和（ii） 0.1N〜5N。 构成二氧化硅团聚体的二氧化硅粒子的平均粒径可以为1μm〜50μm。 组合物可以具有10至90BKU的粘度。 本发明还提供了通过将本发明的口腔护理组合物施用于受试者的牙齿表面来鼓励适当的牙齿清洁的方法。 本发明还提供二氧化硅附聚物在制造口腔护理组合物中用于鼓励适当牙齿清洁的用途
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公开(公告)号：US11883520B2
公开(公告)日：2024-01-30
申请号：US16899882
申请日：2020-06-12
发明人： Ross Strand , Yang Su , Yunming Shi , Thanigaivel Shanmugam , Guannan Wang , Xiaoxiao Li
CPC分类号： A61K8/735 , A61K8/042 , A61K8/4946 , A61K8/8147 , A61Q11/00 , A61K2800/30 , A61K2800/87 , A61K2800/92
摘要： Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Said leave-on oral care compositions comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer and an additional polymer.
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公开(公告)号：US11622925B2
公开(公告)日：2023-04-11
申请号：US17024838
申请日：2020-09-18
发明人： Ross Strand , Xiaoxiao Li , Yunming Shi
IPC分类号： A61Q11/00 , A61K8/21 , A61K8/27 , A61K6/00 , A61K8/60 , A61K8/365 , A61K8/44 , A61K8/25 , A61K8/34
摘要： Dentifrice compositions comprising zinc lactate, glycine, and fluoride ion are provided for treating dental plaque biofilm.
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公开(公告)号：US20210338538A1
公开(公告)日：2021-11-04
申请号：US17367786
申请日：2021-07-06
发明人： Ross Strand , Yujun Li , Yiqun Zhang , Xiaoxiao Li , Zhong Lei
摘要： The present invention provides an oral care composition, containing at least 0.5% by weight of silica agglomerates, wherein each of the silica agglomerates has: (i) an overall particle size from 200 μm to 2000 μm, and (ii) a crush strength from 0.1N to 5N. The silica particles that make up the silica agglomerate can have an average particle size from 1 μm to 50 μm. The composition can have a viscosity from 10 to 90 BKU. The present invention also provides a method of encouraging proper tooth cleaning by administering the oral care composition of the present invention to a subject's tooth surface. The present invention further provides the use of a silica agglomerate in manufacturing an oral care composition for encouraging proper tooth cleaning.
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公开(公告)号：US10213368B2
公开(公告)日：2019-02-26
申请号：US14633389
申请日：2015-02-27
发明人： Xiaoxiao Li , Yujun Li , Ross Strand , Andrew Frederic Broth , William Michael Glandorf , Steven Carl Burgess , Xiujun Xu
摘要： Oral care composition comprise a stannous ion source and a thickener consisting essentially of carrageenan and xanthan gum. A method for treating the oral cavity comprises administering the composition to the oral cavity in a toothpaste.
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公开(公告)号：US09687427B2
公开(公告)日：2017-06-27
申请号：US14633256
申请日：2015-02-27
发明人： Xiaoxiao Li , Yujun Li , Ross Strand , Xiujun Xu
CPC分类号： A61K8/19 , A61K8/20 , A61K8/73 , A61K8/731 , A61K2800/48 , A61K2800/52 , A61K2800/594 , A61Q11/00
摘要： Oral care composition comprises a stannous ion source and a thickener comprising at least 2 agents selected from the group consisting of: i) a linear sulfated polysaccharide; ii) a natural gum; iii) and a non-ionic cellulose derivative. A method for treating the oral cavity comprises administering to the oral cavity the oral care composition.
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