摘要:
Tour guide contents stored in a tour guide apparatus carried by a user at a tour destination are provided with points of interest information and map data. This information includes latitude and longitude information for the site of each point of interest, and information on the providers of the information and the categories of information. The latitude and longitude information is provided for each site in relation to map data. By matching these pieces of latitude and longitude information to the map data, points of interest information can be laid out on the map and displayed. This makes it possible to select interesting site information to be displayed on the map based on the information provider, for example, points of interest information provided by provider A for restaurants and another set of information provided by provider B for hotels.
摘要:
The present invention provides C-glycoside derivatives and salts thereof, wherein B ring is bonded to A ring via —X— and A ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes related diseases such as an insulin-resistant diseases and obesity.
摘要:
A process for producing an azulene derivative useful as a Na+-glucose cotransporter inhibitor, which is high in yield, is simple in operation, is low in cost, is suited for environmental protection, and is advantageous industrially, the process being characterized by reducing and deprotecting at least one compound selected from penta-acyl compounds and tetra-acyl compounds or salts thereof to obtain a C-glycoside compound; and a useful intermediate for synthesis of such an azulene derivative, obtained in the course of the above process.
摘要:
The present invention provides C-glycoside derivatives and salts thereof, wherein B ring is bonded to A ring via —X— and A ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes related diseases such as an insulin-resistant diseases and obesity.
摘要:
The present invention provides an azulene derivative and a salt thereof, wherein an azulene ring is bonded to a benzene ring directly or via a lower alkylene which may be substituted with a halogen atom and the benzene ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes-related diseases such as insulin-resistant diseases and obesity.
摘要:
The present invention is a compound of general formula (I) or a pharmaceutically acceptable salt of, wherein W represents carbon chain from 9 to 17 which containing double bond or hydroxy group occasionally; X represents carbon chain from 11 to 25 which containing double bond or hydroxy group occasionally; Y represents —(CH2)a—CH═CH—(CH2)a′—, —(CH2)a— (a, a′ denotes an integer of 0-5 and a+a′ is 5 and under.), —S(O)0-2CH2—, —NHCH2—; Z represents —CO—, —SO2—; R represents —CH2OH, CO2H, CH2OCH2CO2SO3H; R0 represents —OH, —NH2, —NHAc.
摘要:
C-glycoside derivatives are disclosed, which are represented by the following formula (I) and its pharmaceutical acceptable salt, and which are useful for the treatment and/or prevention of diabetes and hypoglycemia. wherein: with the provisos that R1 is H, OH, lower alkyl, O-lower alkyl or R2 is H, —COO-lower alkyl, R5 is —CH2OH, —CH2OCO2-lower alkyl, —CH2OSO3H, —COOH or —COONa; wherein: A is (with the provisos that X is oxygen atom, nitrogen atom or sulfur atom R3 is lower alkyl when m=0, and is lower alkyl, —OH or —O-lower alkyl when m=1, . . . means saturated or unsaturated carbon bond; m is 0 or 1; n is 0, 1 or 2; above mentioned-lower alkyl means C1-C5.) or a pharmaceutical acceptable salt.
摘要:
An outboard motor comprises, in an installed or mounted state, an engine holder, an engine located to an upper portion of the engine holder, a drive shaft housing located to a lower portion of the engine holder for housing a drive shaft extending downward from the engine, and an oil pan formed to the engine holder, the oil pan being provided with a wall section to which steering brackets are secured through upper mounts. A first seal member is disposed at a mating surface portion of an upper surface of the drive shaft housing and a lower surface of the oil pan and a second seal member is disposed at a mating surface of an upper surface of the oil pan and a lower surface of the engine to thereby expose the drive shaft between the first and second seal members.
摘要:
An image scanner for a document incorporates a transparent member on a lower surface for passing reading and reflecting light while preventing entry of dust and foreign matter into the scanner housing. The transparent member is disposed so that at least the area which passes reflected light is located outside of the depth of field of the scanner optical system.
摘要:
The present invention relates to a thermal printer comprising a thermal head, and means for inhibiting an energization signal for heat generation of said thermal head. The inhibition means prevents the thermal head from being energized when it is in a non-operational position thereby preventing damage to the thermal head.