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    Oil-In-Water Emulsion Type Sunscreen Preparation
    81.
    发明申请
    Oil-In-Water Emulsion Type Sunscreen Preparation 有权
    水包油乳液防晒霜

    公开(公告)号：US20100209365A1

    公开(公告)日：2010-08-19

    申请号：US12670744

    申请日：2007-07-27

    申请人： Yoshihito Takakura ,  Kazuaki Suzuki ,  Takayuki Omura

    发明人： Yoshihito Takakura ,  Kazuaki Suzuki ,  Takayuki Omura

    IPC分类号： A61K8/49 ,  A61Q17/04

    CPC分类号： A61K8/062 ,  A61K8/345 ,  A61K8/35 ,  A61K8/37 ,  A61K8/375 ,  A61K8/40 ,  A61K8/4946 ,  A61K8/4966 ,  A61K8/4973 ,  A61K8/86 ,  A61K2800/52 ,  A61Q17/04 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/941 ,  Y10S514/942

    摘要： The object of the present invention is to provide an oil-in-water emulsified sunscreen cosmetic that is superior in stability and the sensation during use. This object is achieved by providing an oil-in-water emulsified sunscreen cosmetic that satisfies all of the following conditions (A), (B), (C), (D), and (E):(A) Containing the following three types of surfactants (A-1)-(A-3) in the amount of 1-6 wt % of the total amount of the cosmetic (A-1) A POE stearic ester having a POE mole number of 20-120 (A-2) Sorbitan tristearate (A-3) Glyceryl stearate having a HLB of 5-8 (B) Containing the following oil soluble ultraviolet absorbent, which is solid at room temperature, in the amount of 0.01-5 wt % of the total amount of the cosmetic Bis-ethylhexyloxyphenolmethoxyphenyltriazine and/or tert-butylmethoxybenzoylmethane (C) Containing the following oil soluble ultraviolet absorbent, which is liquid at room temperature, in the amount of 1-14 wt % of the total amount of the cosmetic Ethylhexyl methoxycinnamate and/or octocrylene (D) Containing the following water soluble ultraviolet absorbent in the amount of 0.1-5 wt % of the total amount of the cosmetic Phenylbenzimidazolesulfonic acid (E) Containing higher alcohol having 14-24 carbon atoms

    摘要翻译： 本发明的目的是提供在使用中稳定性和感觉优异的水包油乳化防晒化妆品。 该目的通过提供满足以下所有条件（A），（B），（C），（D）和（E）的水包油乳化防晒化妆品来实现：（A）含有以下三种 化妆品（A-1）总量的1-6重量％的表面活性剂（A-1） - （A-3）的种类POE摩尔数为20-120的POE硬脂酸酯（A -2）脱水山梨糖醇三硬脂酸酯（A-3）HLB为5-8的硬脂酸甘油酯（B）含有下述在室温下为固体的油溶性紫外线吸收剂，其量为总量的0.01-5重量％ 化妆品的双 - 乙基己氧基苯酚甲氧基苯基三嗪和/或叔丁基甲氧基苯甲酰甲烷（C）含有以下在室温下为液体的油溶性紫外线吸收剂，其量为化妆品甲氧基肉桂酸乙基己酯总量的1-14wt％ 或八聚氰基（D）含有下述水溶性紫外线吸收剂，其量为总量的0.1-5重量％ 化妆品苯基苯并咪唑磺酸（E）含有14-24个碳原子的高级醇

    Nanoemulsion based on glycerol fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields
    83.
    发明授权
    Nanoemulsion based on glycerol fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields 有权
    基于甘油脂肪酯的纳米乳液及其在化妆品，皮肤病学和/或眼科领域中的应用

    公开(公告)号：US06541018B1

    公开(公告)日：2003-04-01

    申请号：US09461753

    申请日：1999-12-16

    申请人： Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

    发明人： Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

    IPC分类号： A61K700

    CPC分类号： A61Q19/00 ,  A61K8/062 ,  A61K9/0048 ,  A61K9/1075 ,  A61K2800/21 ,  A61K2800/413 ,  A61Q1/14 ,  A61Q19/007 ,  B01F17/0021 ,  B82Y5/00 ,  Y10S514/844 ,  Y10S514/847 ,  Y10S514/88 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/939 ,  Y10S514/941 ,  Y10S514/942 ,  Y10S514/943 ,  Y10S514/975

    摘要： The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one glycerol fatty ester surfactant which is solid at a temperature of less than or equal to 45° C.; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion and methods for its use. Ideally, the emulsion is transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and, in the ophthalmological field, as an eye lotion for treating the eyes.

    摘要翻译： 本发明提供一种纳米乳液，其包括：分散在水相中的油相; 和至少一种甘油脂肪酸酯表面活性剂，其在小于或等于45℃的温度下是固体;其中所述油相包括数均分子量小于100nm的油球;其中所述油相至少包括 一种分子量大于400的油; 并且其中油相与表面活性剂的重量比为2至10.本发明还提供了制备纳米乳液的方法及其使用方法。 理想情况下，乳液在储存时是透明和稳定的。 它理想地含有大量的油，同时保持良好的透明度和良好的化妆品性能。 纳米乳剂在化妆品和皮肤病学领域特别有用，特别是用于保湿皮肤和/或粘膜，以及用于治疗头发，在眼科领域中，作为用于治疗眼睛的眼液。

    Reversible gelation emulsion compositions and methods of use
    89.
    发明授权
    Reversible gelation emulsion compositions and methods of use 失效
    可逆凝胶化乳液组合物及其使用方法

    公开(公告)号：US5441732A

    公开(公告)日：1995-08-15

    申请号：US853135

    申请日：1992-03-18

    申请人： Anne L. Hoeg ,  David L. Meadows

    发明人： Anne L. Hoeg ,  David L. Meadows

    IPC分类号： A61K9/00 ,  A61K9/06 ,  A61K9/107 ,  A61K9/16 ,  A61K47/10 ,  A61K47/18 ,  A61K47/32 ,  A61K47/38 ,  A61K31/19 ,  A01N25/04 ,  A61K31/745

    CPC分类号： A61K9/0048 ,  A61K47/10 ,  A61K47/18 ,  A61K47/32 ,  A61K47/38 ,  A61K9/0019 ,  A61K9/06 ,  A61K9/1647 ,  Y10S514/912 ,  Y10S514/913 ,  Y10S514/914 ,  Y10S514/915 ,  Y10S514/938 ,  Y10S514/942

    摘要： Reversibly gelling aqueous and oil emulsions are disclosed which can be modified to incorporate oil soluble pharmaceutical compounds for delivery to physiological systems in a soluble form and which undergo significant changes in viscosity in response to substantially simultaneous changes in both temperature and pH. The compositions are formed of relatively low concentrations of a stable combination of at least one pH-sensitive reversibly gelling polymer, at least one temperature-sensitive reversibly gelling polymer and at least one organic oil. The compositions can be formulated to exhibit a sol-gel transition over a wide range of conditions and viscosities and may be modified to incorporate a pharmaceutical compound for utilization as droppable or injectable drug delivery systems which will gel following administration to a physiological system for the sustained delivery of such pharmaceutical compounds.

    摘要翻译： 公开了可反射胶凝的水和油乳液，其可以被修饰以引入油溶性药物化合物，以便以可溶形式递送到生理系统，并且响应于温度和pH两者的基本上同时的变化而经历显着的粘度变化。 组合物由相对低浓度的至少一种pH敏感的可逆胶凝聚合物，至少一种温度敏感的可逆胶凝聚合物和至少一种有机油的稳定组合形成。 组合物可以配制成在宽范围的条件和粘度下显示出溶胶 - 凝胶转变，并且可以被修饰以引入药物化合物以用作可滴注或可注射的药物递送系统，其将在施用于生理系统之后凝胶用于持续的 这种药物化合物的递送。