Mild, rinse-off antimicrobial liquid cleansing compositions containing
salicyclic acid
    4.
    发明授权
    Mild, rinse-off antimicrobial liquid cleansing compositions containing salicyclic acid 失效
    含有水杨酸的轻度,漂洗的抗菌液体清洁组合物

    公开(公告)号:US6106851A

    公开(公告)日:2000-08-22

    申请号:US323420

    申请日:1999-06-01

    摘要: The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 6% to about 16%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 100:0 to about 1.5:1; from about 2% to about 4%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75, wherein the proton donating agent is such that the composition is essentially free of C.sub.4 -C.sub.20 alkyl fatty acid, and wherein from about 0.15% to about 2%, by weight of the cleansing composition, of the proton donating agent is salicylic acid; a mildness enhancing agent selected from the group consisting of from about 20% to about 70%, by weight of the anionic surfactant, of a mildness enhancing cosurfactant; from about 0.1% to about 1.0%, by weight of the cleansing composition, of a mildness enhancing polymer; and mixtures thereof, and from about 35% to about 95.75%, by weight of the cleansing composition, of water; wherein the composition is adjusted to a pH of greater than about 3 and less than about 6. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram negative bacteria using these products.

    摘要翻译: 本发明涉及一种洗涤抗微生物清洁组合物,其包含按重量计约0.1%至约5.0%的清洁组合物的抗微生物活性物质; 约6%至约16%的洗涤组合物的阴离子表面活性剂,其中至少约67%的阴离子表面活性剂选自A类表面活性剂,C类表面活性剂及其混合物, 其中A类表面活性剂与C类的比例为约100:0至约1.5:1; 约2%至约4%的清洁组合物,具有大于约0.75的生物活性指数Z的质子供体,其中质子供体剂使得组合物基本上不含C4 -C 20烷基脂肪酸,其中约0.15重量%至约2重量%的所述清洁组合物的质子供体剂为水杨酸; 选自按重量计约20%至约70%的阴离子表面活性剂的温和增强助剂,具有温和增强助表面活性剂; 约0.1%至约1.0%的所述清洁组合物;增温聚合物; 和它们的混合物,和约35%至约95.75%重量的清洁组合物; 其中将组合物调节至大于约3且小于约6的pH。本发明还包括使用这些产品对革兰氏阴性细菌进行清洁皮肤并提供残留效力的方法。

    Polymeric x-ray contrast compositions containing iodinated polymeric
beads and microcrystaline cellulose
    9.
    发明授权
    Polymeric x-ray contrast compositions containing iodinated polymeric beads and microcrystaline cellulose 失效
    含有碘化聚合物珠粒和微晶纤维素的聚合X射线对比组合物

    公开(公告)号:US5525327A

    公开(公告)日:1996-06-11

    申请号:US227415

    申请日:1994-04-14

    IPC分类号: A61K49/04

    摘要: Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising iodinated polymeric, water-insoluble beads having a particle size of from about 0.01 to about 1000.mu. wherein said iodinated polymeric beads comprise a polymer containing repeating units of the formula (I) ##STR1## wherein A is a repeating organic unit in the backbone chain of the polymer; and X is an organic moiety containing or iodinated eromatic group and a hydrophilic group, said moiety having an iodine content within the range of from about 40 to about 80 weight percent based or the molecular weight of X, in a pharmaceutically acceptable carrier comprising a cellulose derivative.

    摘要翻译: 公开了用于口腔或逆行检查胃肠道的X射线造影剂组合物,其包含粒径为约0.01至约1000μm的碘化聚合物,水不溶性珠粒,其中所述碘化聚合物珠粒包含含有式 (I)其中A是聚合物的主链中的重复有机单元; 并且X是含有或碘化的丙烯酸基团和亲水基团的有机部分,所述部分在药学上可接受的载体中具有在约40至约80重量%的范围内或基于X的分子量的碘含量,其包含纤维素 衍生物。