公开(公告)号：US5717087A

公开(公告)日：1998-02-10

申请号：US692028

申请日：1996-08-02

申请人： Jochen Kalbe ,  Reinhard Koch ,  Hanns Peter Muller ,  Jurgen Engelhardt ,  Wolfgang Koch ,  Volkhard Muller

发明人： Jochen Kalbe ,  Reinhard Koch ,  Hanns Peter Muller ,  Jurgen Engelhardt ,  Wolfgang Koch ,  Volkhard Muller

IPC分类号： A61K47/36 ,  A61K9/20 ,  A61K47/38 ,  C08B13/00 ,  C08B31/04 ,  C08B37/00 ,  C08J5/00 ,  C08L5/00 ,  C08L101/16 ,  C09D105/00 ,  D01F2/24 ,  D21H19/44 ,  D21H19/52

CPC分类号： C08B13/00 ,  A61K9/2054 ,  A61K9/2059 ,  C08B31/04 ,  Y02W30/43

摘要： The present invention relates to thermoplastic and biodegradable polysaccharide esters/polysaccharide ether esters, which are characterised in that they can be represented by the general structure ##STR1## wherein Polysaccharide-O represents the substituted OH groups of a polymeric saccharide unit and wherein A is a linear polyether chain of the following structure A=(E--O)n wherein E signifies a linear aliphatic or aromatic branched or unbranched chain having 2 to 11 C atoms, n is an integer equal to or greater than 0 and both B and D are a maleic acid addition product of the following structure ##STR2## wherein F is an aliphatic, saturated, monounsaturated or polyunsaturated carbon skeleton, which may optionally be provided with further substituents and wherein C can be a hydrogen atom, one or more substituents from the group dihydroxyethyl, hydroxypropyl, hydroxybutyl, methyl, ethyl, benzyl, dihydroxypropyl, carboxyalkyl, sulphoalkyl or cyanoethyl.

摘要翻译： 本发明涉及热塑性和可生物降解的多糖酯/多糖醚酯，其特征在于它们可以由通式结构表示，其中多糖-O代表聚合糖单元的取代的OH基团，其中A是 具有以下结构的线性聚醚链A =（EO）n，其中E表示具有2至11个C原子的直链脂族或芳族支链或非支链，n为等于或大于0的整数，B和D均为马来酸加成 具有以下结构的产物其中F是脂族饱和的单不饱和或多不饱和碳骨架，其可以任选地被提供另外的取代基，并且其中C可以是氢原子，一个或多个二羟基乙基，羟丙基， 羟基丁基，甲基，乙基，苄基，二羟基丙基，羧基烷基，磺基烷基或氰基乙基。

公开(公告)号：US5530111A

公开(公告)日：1996-06-25

申请号：US296171

申请日：1994-08-29

申请人： Wolfgang G. Glasser ,  Charles E. Frazier ,  Gamini Samaranayake

发明人： Wolfgang G. Glasser ,  Charles E. Frazier ,  Gamini Samaranayake

IPC分类号： C08B3/00 ,  C08B3/14 ,  C08B5/00 ,  C08B7/00 ,  C08B11/00 ,  C08B13/00

CPC分类号： C08B3/00 ,  C08B3/14

摘要： A method is described for the chemical modification of pre-shaped hydrogels in non-aqueous medium. The conditions permit the reaction of highly expanded, porous hydrogel particles, such as spherical beads, using pseudo homogeneous reaction conditions in the absence of water. The method involves a three step procedure in which the porous gels are solvent exchanged int a water-free solvent (step 1) with minimal change in gel dimension and porosity; followed by reaction under non-aqueous condition (step 2); and followed by solvent exchange into water (step 3). Many different types of reactions requiring non-aqueous conditions may be carried out using these conditions. The method has particularly been demonstrated for crosslinking fluorinating beads, and for esterifying beads in a reaction involving multifunctional free carboxylic acids in the presence of dicyclohexylcarbodiimide (DCC).

摘要翻译： 描述了一种用于非水介质中预形状水凝胶的化学改性的方法。 该条件允许在不存在水的情况下使用假均匀反应条件使高度膨胀的多孔水凝胶颗粒如球形珠的反应。 该方法涉及三步法，其中多孔凝胶在无水溶剂（步骤1）中溶剂交换，凝胶尺寸和孔隙率变化最小; 然后在非水条件下反应（步骤2）; 然后进行与水的溶剂交换（步骤3）。 可以使用这些条件进行需要非水性条件的许多不同类型的反应。 特别是在二环己基碳化二亚胺（DCC）的存在下，涉及氟化珠的交联以及涉及多官能游离羧酸的反应中的酯化珠粒的方法。

公开(公告)号：US5484903A

公开(公告)日：1996-01-16

申请号：US941495

申请日：1992-09-08

申请人： Klaus Szablikowski ,  Hans-Josef Buysch ,  Alexander Klausener

发明人： Klaus Szablikowski ,  Hans-Josef Buysch ,  Alexander Klausener

IPC分类号： C08B5/00 ,  C08B13/00 ,  C08B31/06 ,  C07H1/00 ,  C07H13/02 ,  C08B31/00 ,  C08B37/00

CPC分类号： C08B5/00 ,  C08B13/00 ,  C08B31/06

摘要： The invention relates to a process for the production of carbonic acid esters of polysaccharides which is characterized in that polysaccharides are reacted with carbonic acid esters.

摘要翻译： 本发明涉及一种生产多糖碳酸酯的方法，其特征在于多糖与碳酸酯反应。

公开(公告)号：US4997935A

公开(公告)日：1991-03-05

申请号：US316336

申请日：1989-02-27

申请人： Michael Diamantoglou

发明人： Michael Diamantoglou

IPC分类号： C08B3/00 ,  B01D71/08 ,  B01D71/10 ,  B01D71/12 ,  C08B13/00 ,  C08B15/00 ,  C08B15/06 ,  C08B37/08

CPC分类号： B01D71/08 ,  B01D71/10 ,  B01D71/12 ,  C08B13/00 ,  C08B15/06 ,  C08B37/003

摘要： A modified cellulose for biocompatible dialysis membranes having a structure represented by the formula ##STR1## wherein cell is cellulose or chitin, in each case without hydroxyl groups, s=3 in the case of cellulose and s=2 in the case of chitin, R' is CH.sub.3 and/or C.sub.2 H.sub.5 and/or C.sub.3 H.sub.7, X denotes specified functional groups, R" is H or R, R"' denotes R, x+t=0.75 to 2.85, t=0 to 2.85, x=0 to 2.85, and r=0 to 1. A process for preparation of the cellulose derivatives is also disclosed.

摘要翻译： 用于生物相容性透析膜的改性纤维素，其具有由下式表示的结构：其中细胞是纤维素或几丁质，在每种情况下不含羟基，在纤维素的情况下s = 3，在甲壳质的情况下s = 2; R '是CH3和/或C2H5和/或C3H7，X表示指定的官能团，R“是H或R，R”'表示R，x + t = 0.75至2.85，t = 0至2.85，x = 0 至2.85，r = 0至1.还公开了制备纤维素衍生物的方法。

公开(公告)号：US4749800A

公开(公告)日：1988-06-07

申请号：US85825

申请日：1987-08-17

申请人： Patrick G. Jobe ,  Diane J. Lamb ,  Gary T. Martino

发明人： Patrick G. Jobe ,  Diane J. Lamb ,  Gary T. Martino

IPC分类号： C08B3/14 ,  C08B13/00 ,  C08B31/00 ,  C08B31/04 ,  C08B37/00 ,  D21H17/24 ,  D21H21/18 ,  C07D317/00 ,  C07C103/60

CPC分类号： C08B31/003 ,  C08B13/00 ,  C08B3/14 ,  C08B31/04 ,  C08B37/0087 ,  D21H17/24 ,  D21H21/18

摘要： Polysaccharide esters containing aldehyde and acetal groups having the structural formulas ##STR1## are prepared by reacting a polysaccharide, such as a starch, gum, or cellulose, with an acetal-containing reagent which contains a functional group reactive with the hydroxyl groups of the polysaccharide; Z is a multivalent organic group: A and A' are independently a lower alkyl or together form at least a 5-membered cyclic acetal; x is at least 1; and y is at least 1. When x is >1 the esters are crosslinked. Typical reagents for introducing the acetal group include 3,3-diethoxypropionyl guanidine (itself a novel compound) and 4-(methylaminoacetaldehyde dimethyl acetal)-4-oxo-butanoic acid). The derivatives are useful in conventional applications such as coatings, adhesives, paper additives and foodstuffs.

摘要翻译： 含有结构式 + TR 的醛和缩醛基的多糖酯通过使多糖如淀粉，胶或纤维素与含缩醛试剂反应来制备，所述试剂含有与 多糖的羟基; Z是多价有机基团：A和A'独立地是低级烷基或一起形成至少5元环状缩醛; x至少为1; 并且y至少为1.当x> 1时，酯交联。 用于引入缩醛基团的典型试剂包括3,3-二乙氧基丙酰基胍（其本身是新化合物）和4-（甲基氨基乙醛二甲基缩醛）-4-氧代 - 丁酸）。 该衍生物可用于常规应用如涂料，粘合剂，纸添加剂和食品。

公开(公告)号：US4749414A

公开(公告)日：1988-06-07

申请号：US942410

申请日：1986-12-16

申请人： Marinda L. Wu ,  John F. Voeks

发明人： Marinda L. Wu ,  John F. Voeks

IPC分类号： C08B13/00 ,  C08J7/04 ,  C08L1/32 ,  C09J3/04 ,  C09K3/30

CPC分类号： C08J7/047 ,  C08B13/00 ,  C08J2401/00

摘要： The invention relates to a composition useful for producing a modifying adherent layer on a passive polymeric material, said composition comprising (A) a fluorinated ester substituted alkoxy cellulose having, on the average, between about 1.0 to 2.99 of the three reactive hydroxyl groups of each glucose unit present as alkoxy groups, and the remainder of the reactive hydroxyl groups of each glucose unit present as a fluoroester group of the formula: ##STR1## wherein R.sub.f is branched perfluoroalkyl comprising 3 to 20 carbon atoms; or --(CF.sub.2).sub.n CF.sub.2 --Q, wherein Q is hydrogen of fluorine; n is an integer from 1 to 19; or ##STR2## wherein X is selected from the group consisting of --F, --CF.sub.3 and --CF.sub.2 Cl, Y is --F, --Cl, --CF.sub.2 Cl or perfluoroalkyl having from 1 to 10 carbon atoms, Z is --F, --Cl, --CF.sub.3 or CF.sub.2 Cl, and m is an integer from 1 to 12; and (B) an organic solvent. The composition may be in an enclosed container having integral fluid delivery means such as a gas-pressurized container or a container having a manual pump.

摘要翻译： 本发明涉及一种可用于在被动聚合物材料上生产改性粘合层的组合物，所述组合物包含（A）氟化酯取代的烷氧基纤维素，其平均来说在每个的三个反应性羟基中的平均约为1.0至2.99 葡萄糖单元作为烷氧基存在，并且每个葡萄糖单元的剩余的反应性羟基作为下式的氟酯基存在：（i）其中R f为包含3至20个碳原子的支链全氟烷基; 或 - （CF 2）n CF 2 -Q，其中Q是氟的氢; n是1至19的整数; 或（ii）其中X选自-F，-CF 3和-CF 2 Cl，Y为-F，-Cl，-CF 2 Cl或具有1至10个碳原子的全氟烷基，其中Z为 -F，-Cl，-CF 3或CF 2 Cl，m为1〜12的整数。 和（B）有机溶剂。 组合物可以在具有整体流体输送装置的封闭容器中，例如气体加压容器或具有手动泵的容器。

公开(公告)号：US4226981A

公开(公告)日：1980-10-07

申请号：US944177

申请日：1978-09-20

申请人： Yoshiro Onda ,  Hiroaki Muto ,  Kazumasa Maruyama

发明人： Yoshiro Onda ,  Hiroaki Muto ,  Kazumasa Maruyama

IPC分类号： A61K9/28 ,  A61K9/36 ,  C08B13/00 ,  G03C1/835 ,  B44D1/50 ,  G03C1/92

CPC分类号： A61K9/2866 ,  C08B13/00 ,  G03C1/835

摘要： A novel cellulose derivative provided in this invention is a mixed ester of an alkoxy or hydroxyalkoxy substituted cellulose ether, prepared by the esterification reaction of the ether with succinic anhydride and an anhydride of an aliphatic monocarboxylic acid. The cellulose derivatives are advantageous because of their capability of producing enteric coatings having sufficient flexibility without the use of a plasticizer as well as by their chemical and physical stability against moisture, and also by easy purification after completion of the esterification reaction. The coatings produced from the derivatives have a similar chemical and physical stability. The cellulose derivatives are useful for the enteric coating of pharmaceutical dosage forms and also for providing halation-preventing layers on photographic films.

摘要翻译： 本发明提供的新型纤维素衍生物是通过醚与琥珀酸酐的酯化反应和脂族一元羧酸的酸酐制备的烷氧基或羟基烷氧基取代的纤维素醚的混合酯。 纤维素衍生物是有利的，因为它们具有在不使用增塑剂的情况下具有足够柔韧性的肠溶衣的能力，以及它们对水分的化学和物理稳定性以及酯化反应完成后容易的纯化。 由衍生物生产的涂料具有相似的化学和物理稳定性。 纤维素衍生物可用于药物剂型的肠溶包衣以及用于在照相胶片上提供防晕层。

公开(公告)号：US3974139A

公开(公告)日：1976-08-10

申请号：US488297

申请日：1974-07-12

申请人： Rimas-Kazimeras Mechislovo Noreika ,  Juozas-Romanas Juozo Musnitskas ,  Iolanta Vladimiro Lesene ,  Ionas Iona Zdanavichjus

发明人： Rimas-Kazimeras Mechislovo Noreika ,  Juozas-Romanas Juozo Musnitskas ,  Iolanta Vladimiro Lesene ,  Ionas Iona Zdanavichjus

IPC分类号： C08B11/20 ,  C08B13/00 ,  C08B11/193

CPC分类号： C08B11/20 ,  C08B13/00

摘要： The invention relates to diethylaminohydroxypropyl derivatives of cellulose I or II having maximum weight percentage of nitrogen of 1.6 and 6.3 respectively, and having the power to sorb 7.5 - 14 and 11.5 - 36 per cent of water, respectively, at a temperature of 20.degree.C and a relative humidity of 63 per cent. The invention relates also to the method for preparing these cellulose derivatives which consists in treating diethylaminohydroxypropyl derivatives of cellulose I or II having maximum weight percentage of nitrogen of 1.6 and 6.3 respectively and having the power to sorb a maximum of 7.3 or 11 per cent of water respectively, at a temperature of 20.degree.C and relative humidity of 63 percent, with acetic acid or with its aqueous solutions, taking not less than 0.1 mole of acetic acid per mole of diethylaminohydroxypropyl groups. The proposed derivatives of cellulose have highly accessible structure, increased reactivity and lowered chromacity. They can be used in various branches of science and technology in the capacity of ion-exchange materials, for example, in separation and purification of biochemical objects, in the capacity of complexing agents, for example, in purification and concentration of metals, in the capacity of catalysts, etc..

摘要翻译： 本发明涉及分别具有最大重量百分比为1.6和6.3的纤维素I或II的二乙基氨基羟丙基衍生物，并且具有分别在20℃的温度下吸附7.5-14和11.5-36％的水的功率 相对湿度为63％。 本发明还涉及制备这些纤维素衍生物的方法，该方法包括分别处理最大重量百分比为1.6和6.3的纤维素I或II的二乙基氨基羟丙基衍生物，并具有最多吸收7.3或11％的水 分别在20℃和相对湿度为63％的温度下，与乙酸或其水溶液相比，每摩尔二乙基氨基羟丙基不少于0.1摩尔的乙酸。 所提出的纤维素衍生物具有高度可接近的结构，增加的反应性和降低的色度。 它们可以用于离子交换材料的各种科学和技术部门，例如在生物化学物质的分离和纯化中，以络合剂的能力，例如金属的净化和浓缩，在 催化剂的能力等。

公开(公告)号：US3940384A

公开(公告)日：1976-02-24

申请号：US387894

申请日：1973-08-13

申请人： James Teng ,  Frank Dai ,  Marcella C. Stubits

发明人： James Teng ,  Frank Dai ,  Marcella C. Stubits

IPC分类号： C08B11/193 ,  C08B13/00

CPC分类号： C08B11/193 ,  C08B13/00

摘要： This disclosure involves the acetate ester of methyl hydroxypropyl cellulose. This particular cellulose ester is useful as a gelling agent for organic solvents. The methyl hydroxypropyl cellulose acetate is prepared by the simultaneous hydroxypropylation and methylation of cellulose and by the continuation of the cellulose derivatization into acetylation. The overlapping relationship of the hydroxypropylation and acetylation processes is found to be efficient and economical in that it eliminates the difficulty of isolation and recovery of the water insoluble methyl hydroxypropyl cellulose.

摘要翻译： 本公开涉及甲基羟丙基纤维素的乙酸酯。 该特定的纤维素酯可用作有机溶剂的胶凝剂。 通过纤维素的同时羟丙基化和甲基化以及通过将纤维素衍生化继续进行乙酰化来制备乙酸甲基羟丙基纤维素。 发现羟丙基化和乙酰化过程的重叠关系是有效和经济的，因为它消除了水不溶性甲基羟丙基纤维素的分离和回收的困难。

公开(公告)号：US3891621A

公开(公告)日：1975-06-24

申请号：US40640873

申请日：1973-10-15

申请人： US AGRICULTURE

发明人： ARTHUR JR JETT C ,  BAINS MALKAIT S

IPC分类号： C07H15/04 ,  C07H23/00 ,  C08B5/00 ,  C08B13/00 ,  C08B15/05 ,  D06M13/503 ,  C07C47/18

CPC分类号： C07H15/04 ,  C07H23/00 ,  C08B5/00 ,  C08B13/00 ,  C08B15/05 ,  D06M13/503

摘要： This invention relates to a method for preparing carbohydrateboron alkoxide compounds. Under anhydrous conditions, stable compounds of methyl- Alpha -D-glucoside, methyl- Alpha mannoside, sucrose, cellobiose, methyl cellulose, and cellulose and boron alkoxides, such as boron ethoxide, boron prepoxide, and boron isopropoxide, were prepared in neat boron alkoxide, the parent alcohol, benzene, pyridine, and/or ethylenediamine. The method of this invention has as its objective increasing the reactivity of carbohydrates, as their molecular weights increase, with boron alkoxides by treatment in solutions of strong bases, such as pyridine and ethylenediamine. Formation of carbohydrateboron alkoxide compounds modifies the rate of oxidation of carbohydrates and is related to preparing flame-resistant products.