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    PULVERIZED FIBRIN CLOTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    62.
    发明申请
    PULVERIZED FIBRIN CLOTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
    PULVERIZED FIBRIN CLOTS和含有它们的药物组合物

    公开(公告)号：US20100331254A1

    公开(公告)日：2010-12-30

    申请号：US12810516

    申请日：2008-12-25

    申请人： Ascher Shmulewitz ,  Mazal Dahan ,  Raphael Gorodetsky

    发明人： Ascher Shmulewitz ,  Mazal Dahan ,  Raphael Gorodetsky

    IPC分类号： A61K38/36 ,  C07K14/745 ,  A61P43/00 ,  A61P17/00 ,  A61P19/04

    CPC分类号： A61L24/0031 ,  A61L24/0047 ,  Y10T428/2982

    摘要： Provided is a pulverized fibrin clot and a pharmaceutical composition including a pulverized fibrin clot. The pharmaceutical composition may contain the pulverized fibrin clot suspended in a gel such as cross-linked hyaluronic acid. The pharmaceutical composition may be in a form suitable for injection and may be used, for example, in the treatment of connective tissue, such as skin connective tissue. Also provided is a method for preparing a pulverized fibrin clot as well as a method for treating connective tissue using the pharmaceutical composition.

    摘要翻译： 提供了一种粉碎的纤维蛋白凝块和包含粉碎的纤维蛋白凝块的药物组合物。 药物组合物可以含有悬浮在凝胶如交联透明质酸中的粉碎的纤维蛋白凝块。 药物组合物可以是适合注射的形式，并且可以用于例如结缔组织如皮肤结缔组织的治疗。 还提供了制备粉碎的纤维蛋白凝块的方法以及使用该药物组合物治疗结缔组织的方法。

    Stent coating device
    64.
    发明授权
    Stent coating device 有权

    公开(公告)号：US07048962B2

    公开(公告)日：2006-05-23

    申请号：US10210714

    申请日：2002-07-30

    申请人： Avraham Shekalim ,  Ascher Shmulewitz

    发明人： Avraham Shekalim ,  Ascher Shmulewitz

    IPC分类号： A61L27/00

    CPC分类号： B05C5/0216 ,  B05B12/12 ,  B05B13/0442

    摘要： The present invention is a method and device, which is suitable for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device, for example a stent. Disclosed is a device for use with a stent deployed on a catheter balloon. The device is configured to apply a medical coating of a desired thickness to the surface of a stent only. This is done by use of a drop-on-demand inkjet printing system in association with an optical scanning device. The device is further configured so as to, if necessary, apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness. The section of the housing in which the stent is held during the coating procedure is detachable from the housing base. The detachable housing section may be easily cleaned and re-sterilized or simply disposed or simply disposed of.

    Stent coating device
    65.
    发明申请
    Stent coating device 审中-公开
    支架涂装装置

    公开(公告)号：US20050241577A1

    公开(公告)日：2005-11-03

    申请号：US11178638

    申请日：2005-07-11

    申请人： Avraham Shekalim ,  Ascher Shmulewitz

    发明人： Avraham Shekalim ,  Ascher Shmulewitz

    IPC分类号： B05B12/12 ,  B05B13/04 ,  B05C5/02 ,  B05C11/00 ,  B05D3/00

    CPC分类号： B05C5/0216 ,  B05B12/12 ,  B05B13/0442

    摘要： The present invention is a method and device, which is suitable for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device, for example a stent. Disclosed is a device for use with a stent deployed on a catheter balloon. The device is configured to apply a medical coating of a desired thickness to the surface of a stent only. This is done by use of a drop-on-demand ink-jet printing system in association with an optical scanning device. The device is further configured so as to, if necessary, apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness. The section of the housing in which the stent is held during the coating procedure is detachable from the housing base. The detachable housing section may be easily cleaned and re-sterilized or simply disposed of.

    摘要翻译： 本发明是适于在植入之前适用于手术室中的方法和装置，用于选择性地将医用涂层施加到可植入医疗装置，例如支架上。 公开了一种与部署在导管气囊上的支架一起使用的装置。 该装置被配置成将仅具有所需厚度的医用涂层施加到支架的表面。 这通过使用与光学扫描装置相关联的按需喷墨打印系统来完成。 该装置进一步构造成如果需要，施加多个分层涂层，每个分层涂层是不同的涂层材料，并且如果适当，则具有不同的厚度。 支架在涂覆过程中保持的壳体的部分可从壳体基座拆卸。 可拆卸的壳体部分可以容易地清洁和重新灭菌或简单地处理。

    Stent coating device
    66.
    发明授权
    Stent coating device 失效

    公开(公告)号：US06916379B2

    公开(公告)日：2005-07-12

    申请号：US10661930

    申请日：2003-09-15

    申请人： Avraham Shekalim ,  Ascher Shmulewitz

    发明人： Avraham Shekalim ,  Ascher Shmulewitz

    IPC分类号： B05B12/12 ,  B05B13/04 ,  B05C5/02 ,  B05C11/00 ,  B05D3/00

    CPC分类号： B05C5/0216 ,  B05B12/12 ,  B05B13/0442

    摘要： The present invention is a method and device, which is suitable for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device, for example a stent. Disclosed is a device for use with a stent deployed on a catheter balloon. The device is configured to apply a medical coating of a desired thickness to the surface of a stent only. This is done by use of a drop-on-demand ink-jet printing system in association with an optical scanning device. The device is further configured so as to, if necessary, apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness. The section of the housing in which the stent is held during the coating procedure is detachable from the housing base. The detachable housing section may be easily cleaned and re-sterilized or simply disposed of.

    Prosthesis coating decision support system
    67.
    发明申请
    Prosthesis coating decision support system 审中-公开
    假体涂层决策支持系统

    公开(公告)号：US20050048194A1

    公开(公告)日：2005-03-03

    申请号：US10654562

    申请日：2003-09-02

    申请人： Ascher Shmulewitz

    发明人： Ascher Shmulewitz

    IPC分类号： A61F2/00 ,  A61F2/82 ,  B05D3/00 ,  G06F19/00

    CPC分类号： A61F2/82 ,  A61F2250/0067 ,  A61F2310/00389 ,  G16H50/50

    摘要： Systems and methods consistent with embodiments of the present invention are provided for determining whether and how to coat a prosthesis prior to surgery. In accordance with one embodiment of the invention, a method for coating a prosthesis is provided that includes providing information from one or more sources; electronically analyzing the information to generate at least one treatment plan for coating a prosthesis; and instructing a prosthesis coating device to coat the prosthesis based on the treatment plan.

    摘要翻译： 提供了与本发明的实施例一致的系统和方法，用于确定是否以及如何在手术之前涂覆假体。 根据本发明的一个实施例，提供了一种用于涂覆假体的方法，其包括从一个或多个源提供信息; 电子分析信息以产生用于涂覆假体的至少一个治疗计划; 并且指示假体涂覆装置基于治疗计划涂覆假体。

    Pressure-controlled continuous coronary sinus occlusion device and methods of use
    68.
    发明授权
    Pressure-controlled continuous coronary sinus occlusion device and methods of use 有权
    压力控制连续冠状动脉窦闭塞装置及使用方法

    公开(公告)号：US06569145B1

    公开(公告)日：2003-05-27

    申请号：US09275797

    申请日：1999-03-25

    申请人： Ascher Shmulewitz ,  Robert S. Bley ,  Robert L. Wilcox

    发明人： Ascher Shmulewitz ,  Robert S. Bley ,  Robert L. Wilcox

    IPC分类号： A61M3100

    CPC分类号： A61M25/0075 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12136 ,  A61B17/1219 ,  A61M2025/0076 ,  A61M2025/1052 ,  A61M2210/125

    摘要： Apparatus and methods for perfusing ischemic myocardium are provided using a tubular member having an end region adapted to be disposed in a portion of a patient's venous vasculature. The end region includes a lumen and a valve in communication with the lumen that controls pressure within an occluded portion of the vasculature by venting excess blood at a location proximal of a point of occlusion of the vasculature via the valve. An occlusion element optionally may be provided in the end region that retains the tubular member within the patient's venous vasculature and occludes the flow of blow around the lumen.

    摘要翻译： 使用具有适于设置在患者静脉血管系统的一部分中的端部区域的管状构件来提供用于灌注缺血心肌的装置和方法。 端部区域包括内腔和与内腔连通的阀门，其通过经由阀在血管系统闭塞点附近的位置排出多余的血液来控制脉管系统闭塞部分内的压力。 可以在端部区域中设置闭塞元件，该端部区域将管状构件保持在患者的静脉血管内并阻塞围绕管腔的吹气流。

    Methods and apparatus for treating ischemic heart disease by providing transvenous myocardial perfusion
    70.
    发明授权
    Methods and apparatus for treating ischemic heart disease by providing transvenous myocardial perfusion 有权
    通过提供经静脉心肌灌注治疗缺血性心脏病的方法和装置

    公开(公告)号：US06186972B1

    公开(公告)日：2001-02-13

    申请号：US09208807

    申请日：1998-12-09

    申请人： James A. Nelson ,  Ascher Shmulewitz ,  John Burton

    发明人： James A. Nelson ,  Ascher Shmulewitz ,  John Burton

    IPC分类号： A61B1900

    CPC分类号： A61B17/3478 ,  A61B17/320758 ,  A61B18/1492 ,  A61B2017/00252 ,  A61B2017/22077

    摘要： Methods and apparatus for supplying retrograde perfusion of chronically ischemic myocardium by forming one or more transmural passageways between a cardiac chamber and the coronary venous vasculature. The placement, size and number of the passageways are selected, and portions of the venous vasculature or coronary ostium optionally partially or completely occluded, to maintain a parameter related to the pressure attained in the venous vasculature to a value less than a predetermined value.

    摘要翻译： 通过在心室和冠状静脉血管之间形成一个或多个透壁通道来供应慢性缺血心肌逆行灌注的方法和装置。 选择通道的位置，大小和数量，并且静脉血管或冠状口的部分可选地部分或完全闭塞，以将与静脉脉管系统中获得的压力相关的参数保持在小于预定值的值。