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公开(公告)号：US07083588B1
公开(公告)日：2006-08-01
申请号：US09320172
申请日：1999-05-26
申请人： Ascher Shmulewitz , John Burton , Robert S. Bley , Roy Singfatt Chin , Ronald C. Brown , Robert L. Wilcox
发明人： Ascher Shmulewitz , John Burton , Robert S. Bley , Roy Singfatt Chin , Ronald C. Brown , Robert L. Wilcox
IPC分类号： A61M5/00
CPC分类号： A61M1/3621 , A61B17/0057 , A61M1/10 , A61M1/1008 , A61M1/101 , A61M1/1037 , A61M1/1081 , A61M1/1087 , A61M1/1096 , A61M1/12 , A61M1/3613 , A61M25/04 , A61M2205/32 , A61M2210/125
摘要： Apparatus and methods for perfusing ischemic myocardium, and optionally, for reducing the load on a patient's left ventricle, are provided using a inlet conduit having an inlet end configured for insertion into an oxygenated blood source, including without limitation, the left atrium, left ventricle, aorta, pulmonary vein, subclavian artery, brachiocephalic artery, radial artery or femoral artery, coupled to an outlet conduit having an outlet end configured for insertion into the coronary venous vasculature via the coronary ostium. The inlet conduit may include a stylet or elastomeric sleeve that facilitates placement, while the outlet conduit may include a valve for limiting a peak pressure attained in the coronary venous system. A motor-driven or hydraulically-actuated pump optionally may be coupled in the flow path, and control circuitry provided to control the pump with a user selected duty cycle.
摘要翻译： 用于灌注缺血心肌的装置和方法以及任选的用于减轻患者左心室负荷的装置和方法使用入口导管提供，所述入口导管具有被配置用于插入氧合血液源的入口端，包括但不限于左心房，左心室 主动脉，肺静脉，锁骨下动脉，头臂动脉，桡动脉或股动脉，联接到具有经由冠状口插入冠状静脉血管的出口端的出口导管。 入口导管可以包括便于放置的探针或弹性体套筒，而出口导管可以包括用于限制在冠状静脉系统中获得的峰值压力的阀。 可选地，电动驱动或液压致动的泵耦合在流动路径中，以及控制电路，其被提供以用用户选择的占空比来控制泵。
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2.发明授权Pressure-controlled continuous coronary sinus occlusion device and methods of use 有权压力控制连续冠状动脉窦闭塞装置及使用方法公开(公告)号：US06569145B1
公开(公告)日：2003-05-27
申请号：US09275797
申请日：1999-03-25
IPC分类号： A61M3100
CPC分类号： A61M25/0075 , A61B17/12022 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/1219 , A61M2025/0076 , A61M2025/1052 , A61M2210/125
摘要： Apparatus and methods for perfusing ischemic myocardium are provided using a tubular member having an end region adapted to be disposed in a portion of a patient's venous vasculature. The end region includes a lumen and a valve in communication with the lumen that controls pressure within an occluded portion of the vasculature by venting excess blood at a location proximal of a point of occlusion of the vasculature via the valve. An occlusion element optionally may be provided in the end region that retains the tubular member within the patient's venous vasculature and occludes the flow of blow around the lumen.
摘要翻译： 使用具有适于设置在患者静脉血管系统的一部分中的端部区域的管状构件来提供用于灌注缺血心肌的装置和方法。 端部区域包括内腔和与内腔连通的阀门，其通过经由阀在血管系统闭塞点附近的位置排出多余的血液来控制脉管系统闭塞部分内的压力。 可以在端部区域中设置闭塞元件，该端部区域将管状构件保持在患者的静脉血管内并阻塞围绕管腔的吹气流。
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公开(公告)号：US07049346B1
公开(公告)日：2006-05-23
申请号：US08700168
申请日：1996-08-20
IPC分类号： A61F13/00
CPC分类号： A61L27/52 , A61L27/26 , Y10S514/944
摘要： A physiologically acceptable composition comprises a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the particles. The concentration of the organic compound is such that the resulting particles can be inserted, without use of a carrier liquid utilizing a hand driven hypodermic syringe. The swollen hydrogel particles are substantially insoluble in body fluids. The composition is useful for treating urinary tract disorders.
摘要翻译： 生理上可接受的组合物包含在含有低分子量水溶性有机化合物的水溶液中溶胀的多个生理上可接受的水凝胶颗粒，该溶液具有使颗粒溶胀的能力。 有机化合物的浓度使得所得颗粒可以插入，而不使用手动皮下注射器的载体液体。 溶胀的水凝胶颗粒基本上不溶于体液。 该组合物可用于治疗尿路疾病。
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公开(公告)号：US5813411A
公开(公告)日：1998-09-29
申请号：US700004
申请日：1996-08-20
CPC分类号： A61L27/52 , A61L27/26 , Y10S623/915
摘要： A method of treating urinary disorders utilizing a physiologically acceptable composition including a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the particles. The concentration of the organic compound is such that the resulting particles can be inserted, without use of a carrier liquid utilizing a hand driven hypodermic syringe. The swollen hydrogel particles are substantially insoluble in body fluids.
摘要翻译： 一种使用生理上可接受的组合物治疗尿失调的方法，所述组合物包括在含有低分子量水溶性有机化合物的水溶液中溶胀的多个生理上可接受的水凝胶颗粒，所述溶液具有使颗粒膨胀的能力。 有机化合物的浓度使得所得颗粒可以插入，而不使用手动皮下注射器的载体液体。 溶胀的水凝胶颗粒基本上不溶于体液。
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公开(公告)号：US5188596A
公开(公告)日：1993-02-23
申请号：US589048
申请日：1990-09-27
CPC分类号： A61B1/307 , A61B1/00082 , A61B1/042 , A61B1/32 , A61M29/02 , A61B1/07 , A61B2018/00553 , A61M25/1011
摘要： The present invention comprises a prostate dilation balloon disposed on a urethral catheter, a fixation balloon also disposed on said catheter, wherein said catheter is partially or completely transparent, and a fiber optic endoscope disposed within said catheter. The scope is arranged so that it can visualize the area outside the catheter in order to determine whether the dilation balloon and fixation balloon are properly located within their respective targets within the urethra and/or bladder. The scope is also capable of focusing on objects which may be present in and along the urethra.
摘要翻译： 本发明包括设置在尿道导管上的前列腺扩张球囊，还设置在所述导管上的固定球囊，其中所述导管部分或完全透明，以及设置在所述导管内的光纤内窥镜。 范围被布置成使得其可以可视化导管外部的区域，以便确定扩张球囊和固定球囊是否适当地位于其在尿道和/或膀胱内的各自目标内。 范围还可以集中在可能存在于尿道内和沿着尿道的物体上。
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公开(公告)号：US5968070A
公开(公告)日：1999-10-19
申请号：US909520
申请日：1997-08-11
CPC分类号： A61F2/07 , A61L31/10 , A61F2/0077 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2250/0067
摘要： The present invention is a medical device such as a stent in the form of an expandable mesh with an expandable polymer layer thereon. The mesh is metal or plastic. The polymer may be any of a variety of expandable polymers, which either expand upon hydration, or expand without significant resistance. The invention may be used, for example, as an expandable biliary, vascular, endotracheal, esophageal, or prostatic device.
摘要翻译： 本发明是一种医疗装置，例如其上具有可膨胀聚合物层的可扩张网状的支架。 网格是金属或塑料。 聚合物可以是各种可膨胀聚合物中的任何一种，其在水合时膨胀或膨胀而没有显着的阻力。 本发明可以用作例如可扩张的胆管，血管，气管内，食管或前列腺装置。
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公开(公告)号：US5159920A
公开(公告)日：1992-11-03
申请号：US539865
申请日：1990-06-18
申请人： Dennis E. Condon , Robert S. Bley , Bobby Purkait
发明人： Dennis E. Condon , Robert S. Bley , Bobby Purkait
摘要： A scope and stent system, the scope providing visibility not only through the urethra but also through the ureter during the insertion and placement of a ureteral stent. The scope is in the form of a fiber optic bundle having an appropriate provision for lighting and lensing thereof, and preferably having a video camera and monitor responsive to the image formed at the opposite end of the scope for viewing during the scope insertion process. The fiber optic bundle itself is made sufficiently small so that the entire scope may be fabricated with the appropriate dimensions of a typical stent guide wire and made sufficiently flexible for negotiating a tortuous path as required. The scope may be first inserted through an open-ended stent and through the urethra, the bladder and the ureter, and then the stent inserted thereover through the use of an appropriate stent pusher, or alternatively the scope, stent and stent pusher may be advanced together, the scope allowing observation of the procedure and the nature and extent of any obstructions encountered in the insertion process. Alternate embodiments include the provision of an additional working channel within the stent to allow an additional instrument such as a laser lithotriptor to be utilized in conjunction with the placement of the stent, as well as alternate forms of scope systems.
摘要翻译： 范围和支架系统，范围提供可见性，不仅通过尿道，而且通过输尿管插入和放置输尿管支架期间通过输尿管。 范围是光纤束的形式，其具有用于照明和透镜的适当设置，并且优选地具有响应于在示波器插入过程期间用于观察的相对端形成的图像的摄像机和监视器。 光纤束本身被制成足够小，使得整个范围可以用典型的支架导丝的适当尺寸制造，并且根据需要制造成足够灵活的谈判曲折路径。 该范围可以首先穿过开放式支架并通过尿道，膀胱和输尿管插入，然后通过使用合适的支架推动器插入其中的支架，或者替代物，支架和支架推动器可以是先进的 在一起，允许观察程序的范围以及插入过程中遇到的任何障碍物的性质和程度。 替代实施例包括在支架内提供额外的工作通道，以允许附加的仪器例如激光碎石机与支架的放置一起使用，以及范围系统的替代形式。
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公开(公告)号：US4475898A
公开(公告)日：1984-10-09
申请号：US371756
申请日：1982-04-26
CPC分类号： A61M25/0075 , A61M25/007 , A61M25/04 , A61M25/1011 , A61M27/006 , A61M2027/004 , A61M2210/145
摘要： A fetal shunt is disclosed which comprises a tubular body having a proximal end and a distal end. The proximal end is provided with openings which extend into a lumen which forms a fluid-flow passageway extending between the proximal and distal ends. Either flanges or inflatable cuffs, which can be inflated to form a balloon extending around the tubular body, are provided intermediate the length of the tubular body. The outwardly projecting flanges or the inflated cuff portions form projections which maintain the position of the fetal shunt after it is implanted. The distal end of the tubular body of the shunt is provided with a valve for permitting fluid flow outwardly of the tubular body. The shunt provides a method for transferring cerebral spinal fluid from the fetal cranium to the amniotic fluid surrounding the fetus.
摘要翻译： 公开了一种胎分流器，其包括具有近端和远端的管状体。 近端设置有开口，其延伸到内腔中，该内腔形成在近端和远端之间延伸的流体流动通道。 可以在管状体的长度之间设置可膨胀以形成围绕管状体延伸的气囊的凸缘或可充气袖带。 向外突出的凸缘或充气的袖带部分形成在植入之后保持胎儿分流器的位置的突起。 分流器的管状体的远端设置有用于允许流体从管状体向外流动的阀。 分流器提供将脑脊髓液从胎儿颅骨转移到胎儿周围的羊水的方法。
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公开(公告)号：US5964744A
公开(公告)日：1999-10-12
申请号：US316933
申请日：1994-10-03
IPC分类号： A61F2/04 , A61F2/94 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/00 , A61M25/04 , A61M25/16
CPC分类号： A61M27/008 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/04 , A61F2/94 , A61F2002/041 , A61L2400/16 , A61M2025/0293
摘要： In accordance with the invention, there are provided medical devices with incorporated shape memory systems that allow a polymeric medical device to be inserted in a first conformation or configuration and revert to a second conformation or configuration. The invention is useful in allowing the easy insertion or implantation of a device followed by expansion of the device in order to be retained without expulsion from a body cavity, for example. In another aspect of the invention there is provided a medical device, such as a ureteral stent, that includes comprising an elongated member having a proximal end portion and a distal end portion joined by a body portion. The elongated member has an initial outer diameter. A retention construction serves for retaining the member within a bodily cavity. The member is formulated of a physiologically acceptable polymer capable of hydrating and expanding from the initial member outer diameter to form a final member outer diameter. The device can assume differing shapes and can exhibit different degrees of softening at different places along its length and possess shape memory so that it can be inserted in a first conformation or configuration and revert to a second conformation or configuration upon the occurrence of a triggering event such as hydration.
摘要翻译： 根据本发明，提供了具有结合的形状记忆系统的医疗装置，其允许聚合物医疗装置以第一构象或构型插入并恢复到第二构象或构型。 本发明可用于允许容易地插入或植入装置，然后扩张装置，以便例如在不从体腔排出的情况下保持。 在本发明的另一方面，提供了一种医疗装置，例如输尿管支架，其包括细长构件，该细长构件具有由主体部分连接的近端部分和远端部分。 细长构件具有初始外径。 保持构造用于将构件保持在身体腔内。 该构件配制有能够从初始构件外径水合和膨胀以形成最终构件外径的生理上可接受的聚合物。 该装置可以呈现不同的形状并且可以在其长度上的不同位置显示不同程度的软化，并且具有形状记忆，使得其可以以第一构象或构型插入并且在发生触发事件时恢复到第二构象或构型 如水合。
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公开(公告)号：US5902832A
公开(公告)日：1999-05-11
申请号：US700170
申请日：1996-08-20
CPC分类号： A61L27/26 , A61L27/52 , Y10S524/916
摘要： A synthesis method is set forth for forming a physiologically acceptable composition comprising a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the particles. The concentration of the organic compound is such that the resulting particles can be inserted, without use of a carrier liquid utilizing a hand driven hypodermic syringe. The swollen hydrogel particles are substantially insoluble in body fluids. The method comprises contacting not fully swollen hydrogel particles with the organic compound and with water.
摘要翻译： 阐述了一种用于形成生理上可接受的组合物的合成方法，所述组合物包含在含有低分子量水溶性有机化合物的水溶液中溶胀的多个生理上可接受的水凝胶颗粒，该溶液具有使颗粒膨胀的能力。 有机化合物的浓度使得所得颗粒可以插入，而不使用手动皮下注射器的载体液体。 溶胀的水凝胶颗粒基本上不溶于体液。 该方法包括使完全溶胀的水凝胶颗粒与有机化合物和水接触。
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