公开(公告)号：US20040053196A1

公开(公告)日：2004-03-18

申请号：US10661692

申请日：2003-09-12

Applicant: WOODWELDING AG

Inventor： Jorg Mayer ,  Marcel Aeschlimann ,  Laurent Torriani

IPC: A61C008/00

CPC classification number: A61C8/0012 ,  A61B17/68 ,  A61B17/70 ,  A61B2017/00955 ,  A61C8/0016 ,  A61C8/0018 ,  A61C8/0019 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/447 ,  A61F2/4611 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30064 ,  A61F2002/30065 ,  A61F2002/30067 ,  A61F2002/30088 ,  A61F2002/30784 ,  A61F2002/30878 ,  A61F2002/30884 ,  A61F2002/30892 ,  A61F2002/30899 ,  A61F2002/4475 ,  A61F2002/4627 ,  A61F2002/4683 ,  A61F2210/0004 ,  A61F2210/0071 ,  A61F2210/008 ,  A61F2250/003 ,  A61L2430/02

Abstract: An implant (1) to be implanted in bone tissue, e.g. a dental implant or an implant for an orthopedic application, comprises surface regions (4) of a first type which have e.g. osseo-integrative, inflammation-inhibiting, infection-combating and/or growth-promoting properties, and surface regions (8) of a second type which consist of a material being liquefiable by mechanical oscillation. The implant is positioned in an opening of e.g. a jawbone and then mechanical oscillations, e.g. ultrasound is applied to it while it is pressed against the bone. The liquefiable material is such liquefied at least partly and is pressed into unevennesses and pores of the surrounding bone tissue where after resolidification it forms a positive-fit connection between the implant and the bone tissue. The surface regions of the two types are arranged and dimensioned such that, during implantation, the liquefied material does not flow or flows only to a clinically irrelevant degree over the surface regions of the first type such enabling the biologically integrative properties of these surface regions to start acting directly after implantation. The implant achieves with the help of the named positive fit a very good (primary) stability, i.e. it can be loaded immediately after implantation. By this, negative effects of non-loading are prevented and relative movements between implant and bone tissue are reduced to physiological measures and therefore have an osseo-integration promoting effect.

Abstract translation: 植入物（1），被植入到骨组织中。 用于矫形应用的牙科植入物或植入物包括第一类型的表面区域（4） 骨整合，炎症抑制，感染对抗和/或生长促进特性以及由可通过机械振荡液化的材料组成的第二类型的表面区域（8）。 植入物定位在例如牙齿的开口中。 颚骨，然后是机械振荡，例如。 当超声被压在骨头上时。 液化材料至少部分地被液化，并且被压制成周围骨组织的不均匀部分和孔隙，其中在重新固定之后，它在植入物和骨组织之间形成正配合连接。 两种类型的表面区域的布置和尺寸设计使得在植入期间，液化材料在第一种类型的表面区域上不流动或仅流过临床上不相关的程度，使得这些表面区域的生物学综合性质 开始植入后直接起作用。 植入物借助命名的正配合实现非常好的（主要）稳定性，即可以在植入后立即加载。 由此，防止非负荷的负面影响，并且将植入物和骨组织之间的相对运动降低为生理测量，因此具有促进骨整合的作用。

公开(公告)号：US12023249B2

公开(公告)日：2024-07-02

申请号：US17049880

申请日：2019-04-25

Applicant: DiaxaMed, LLC

Inventor： Eugene Andrew Grossi ,  William E. Cohn ,  George Gellert ,  Aaron J. Hjelle

IPC: A61F2/24

CPC classification number: A61F2/2481 ,  A61F2002/2484 ,  A61F2210/0019 ,  A61F2210/008 ,  A61F2250/0003 ,  A61F2250/0096

Abstract: Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning. The devices include a cardiac jacket made of a flexible biocompatible material and at least one inflatable bladder disposed on an interior surface of the jacket. Inflation of the bladder causes the bladder to expand to exert localized pressure against a region of the heart. In some cases, a phase-change material is filled into the bladder as a liquid and the material solidifies at body temperature. In some cases, a positioning tool is used prior to the implantation of the jacket in order to determine effective positions for the inflatable bladder(s) to be located on the heart to improve heart functioning.

公开(公告)号：US11944717B2

公开(公告)日：2024-04-02

申请号：US17477947

申请日：2021-09-17

Applicant: Tulavi Therapeutics, Inc. ,  Incept, LLC

Inventor： Corinne Bright ,  Yong Ren ,  Kenneth M. Martin ,  Farhad Khosravi ,  Amarpreet S. Sawhney

IPC: A61B17/11 ,  A61B17/00 ,  A61F2/00 ,  A61F2/02 ,  A61K9/00 ,  A61L27/18 ,  A61L27/26 ,  A61L27/52 ,  A61L31/14

CPC classification number: A61L27/26 ,  A61B17/1128 ,  A61F2/00 ,  A61F2/02 ,  A61K9/0004 ,  A61L27/18 ,  A61L27/52 ,  A61L31/14 ,  A61B2017/00526 ,  A61F2210/00 ,  A61F2210/008 ,  A61F2240/00 ,  A61F2240/001 ,  A61F2250/00 ,  A61L2400/06 ,  A61L2430/32

Abstract: Disclosed are methods, devices and materials for the in situ formation of a nerve cap and/or a nerve wrap to inhibit neuroma formation following planned or traumatic nerve injury. The method includes the steps of identifying a severed end of a nerve, and positioning the severed end into a cavity defined by a form. A transformable media is introduced into the form cavity to surround the severed end. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the severed end. The media may be a hydrogel, and the transformation may produce a synthetic crosslinked hydrogel protective barrier. The media may include at least one anti-regeneration agent to inhibit nerve regrowth.

公开(公告)号：US11819412B2

公开(公告)日：2023-11-21

申请号：US17166062

申请日：2021-02-03

Applicant: Coloplast A/S

Inventor： Frederick William Hamlin ,  John J. Allen ,  Rahul Dilip Sathe ,  Neal Poucher ,  Kellie J. Giese

IPC: A61F2/26

CPC classification number: A61F2/26 ,  A61F2210/008 ,  A61F2250/0058

Abstract: A penile prosthesis has an energy assembly coupled to a proximal end of a tubular body. The energy assembly has a housing enclosing a piston, a heating element, and a liquid phase change material (PCM) sealed between an interior surface of the housing and the piston. When the heating element heats the liquid PCM to a gaseous state, the piston moves in a distal direction to increase pressure in the tubular body and provide the prosthesis with erection.

公开(公告)号：US09889033B2

公开(公告)日：2018-02-13

申请号：US14578370

申请日：2014-12-20

Applicant: Rex Medical, L.P.

Inventor： James F. McGuckin, Jr.

IPC: A61F5/00 ,  A61F5/01

CPC classification number: A61F5/0104 ,  A61F2210/0061 ,  A61F2210/008 ,  A61F2210/0085

Abstract: An orthopedic brace for preventing injury to a wearer including a body having a series of liquid filled regions, the body having a first more flexible state wherein the liquid filled regions contain a liquid material and a second more rigid state wherein the liquid within the regions is hardened to a second harder state, the body transformable from the first state to the second state upon receiving a force which exceeds a predetermined value. A chemical reaction or an isothermal process can cause the phase change.

公开(公告)号：US20150112423A1

公开(公告)日：2015-04-23

申请号：US14579340

申请日：2014-12-22

Applicant: NEW PHASE LTD.

Inventor： Refael HOF ,  Valery PEREVALOV

IPC: A61F2/94 ,  A61F2/04 ,  A61B18/04

CPC classification number: A61F2/94 ,  A61B18/04 ,  A61F2/02 ,  A61F2/04 ,  A61F2/91 ,  A61F7/12 ,  A61F2007/0292 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0066 ,  A61F2210/008 ,  A61F2250/0001 ,  A61F2250/0067 ,  A61N1/086 ,  A61N1/406 ,  A61N2007/0039

Abstract: A method is provided, including, delivering into a heart of a patient an annuloplasty ring structure including a body portion and an adjusting mechanism configured to adjust a size of the body portion of the annuloplasty ring structure, the adjusting mechanism including a housing, and following the delivering, moving the housing with respect to the body portion. Other applications are also described.

Abstract translation: 提供了一种方法，包括向患者的心脏递送瓣膜成形术环结构，所述瓣膜成形术环结构包括主体部分和调节机构，所述调整机构构造成调节瓣膜成形术环结构的主体部分的尺寸，所述调节机构包括壳体， 相对于身体部分递送，移动壳体。 还描述了其它应用。

公开(公告)号：US20140107403A1

公开(公告)日：2014-04-17

申请号：US14133656

申请日：2013-12-19

Applicant: Coloplast A/S

Inventor： Michael M. Witzmann ,  Douglas A. Devens, Jr.

IPC: A61F2/00

CPC classification number: A61F2/0045 ,  A61B17/0401 ,  A61B2017/00805 ,  A61B2017/0464 ,  A61F2210/008 ,  A61F2210/009 ,  A61F2250/0007

Abstract: An incontinence treatment system includes a urethral support extending between a first end and a second end, a first connector attached to the first end of the urethral support and a second connector attached to the second end of the urethral support, and an energy source. At least one of the first connector and the second connector is a cross-linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. In this regard, the cross-linked polymer connector is stretched to provide a stretched cross-linked polymer connector having a product length. The energy source is adapted to provide energy from an extracorporeal location through intact skin to shorten the stretched cross-linked polymer connector to an implant length that is less than the product length.

Abstract translation: 失禁治疗系统包括在第一端和第二端之间延伸的尿道支撑件，连接到尿道支撑件的第一端的第一连接器和连接到尿道支撑件的第二端的第二连接器以及能量源。 第一连接器和第二连接器中的至少一个是玻璃化转变温度在40-70摄氏度之间的交联聚合物连接器。 在这方面，交联聚合物连接器被拉伸以提供具有产品长度的拉伸的交联聚合物连接器。 能源适于从体外位置通过完整皮肤提供能量，以将拉伸的交联聚合物连接器缩短到小于产品长度的植入物长度。

公开(公告)号：US08636644B2

公开(公告)日：2014-01-28

申请号：US13589189

申请日：2012-08-20

Applicant: Michael M Witzmann ,  Douglas Adelbert Devens, Jr.

Inventor： Michael M Witzmann ,  Douglas Adelbert Devens, Jr.

IPC: A61F2/00

CPC classification number: A61F2/0045 ,  A61B17/0401 ,  A61B2017/00805 ,  A61B2017/0464 ,  A61F2210/008 ,  A61F2210/009 ,  A61F2250/0007

Abstract: An incontinence treatment device includes a urethral support and first and second connectors. The urethral support extends between a first end and a second end and has porosity that is configured to allow tissue in-growth through the urethral support. The first connector is attached to the first end of the urethral support and the second connector is attached to the second end of the urethral support. At least one of the first connector and the second connector is a cross-linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. The cross-linked polymer connector has an initial length that is elongated to an implant length that is greater than the initial length. Means for heating the cross-linked polymer connector from an extracorporeal location through intact skin is provided, thereby shortening the cross-linked polymer connector.

Abstract translation: 失禁治疗装置包括尿道支撑件和第一和第二连接器。 尿道支撑件在第一端和第二端之间延伸并且具有构造成允许组织通过尿道支撑生长的多孔性。 第一连接器连接到尿道支撑件的第一端，第二连接器连接到尿道支撑件的第二端。 第一连接器和第二连接器中的至少一个是玻璃化转变温度在40-70摄氏度之间的交联聚合物连接器。 交联聚合物连接器具有延伸到大于初始长度的植入物长度的初始长度。 提供了通过完整皮肤从体外位置加热交联聚合物连接器的手段，从而缩短了交联聚合物连接器。

公开(公告)号：US08550979B2

公开(公告)日：2013-10-08

申请号：US12815440

申请日：2010-06-15

Applicant: Michael M. Witzmann ,  Douglas Adelbert Devens, Jr.

Inventor： Michael M. Witzmann ,  Douglas Adelbert Devens, Jr.

IPC: A61F2/02

CPC classification number: A61F2/0045 ,  A61B17/0401 ,  A61B2017/00805 ,  A61B2017/0464 ,  A61F2210/008 ,  A61F2210/009 ,  A61F2250/0007

Abstract: A method of treating incontinence in a patient includes implanting a support by suspending the support from a pair of connectors attached to tissue thereby supporting a urethra of the patient with an implanted support and a pair of implanted connectors. The method additionally includes evaluating the patient for incontinence post-implantation of the support, and reducing the incontinence of the patient by shortening a length of one of the pair of implanted connectors through intact skin from a location extracorporeal of the patient.

Abstract translation: 一种治疗患者尿失禁的方法包括通过从连接到组织上的一对连接器悬挂支撑来植入支撑物，从而利用植入的支撑物和一对植入的连接器来支撑患者的尿道。 该方法还包括评估患者对支架植入后的失禁，以及通过从患者体外位置的整个皮肤缩短一对植入的连接器中的一个的长度来减少患者的失禁。

公开(公告)号：US20130245754A1

公开(公告)日：2013-09-19

申请号：US13885366

申请日：2011-11-14

Applicant: Ronald David Blum ,  Rudy Mazzocchi

Inventor： Ronald David Blum ,  Rudy Mazzocchi

IPC: A61F2/16

CPC classification number: A61F2/1624 ,  A61F2/1613 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2210/008 ,  A61F2210/009

Abstract: An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

Abstract translation: 具有柔性流体填充膜的可植入眼科装置提供动态可变的光学功率，以恢复患有老花眼或无晶状体的个体的失去的适应性，而无需移动部件或减少透射光量。 驱动该装置导致流体填充的膜改变曲率，这产生相应的光功率变化。 例如，挤压膜的边缘导致膜的中心膨胀与挤压力成比例的量。 或者，加热或向膜施加电压可能导致膜中的液体经历伴随相应的体积变化的相变，导致膜膨胀以改变装置的光功率。