-
公开(公告)号:US20230331649A1
公开(公告)日:2023-10-19
申请号:US18000423
申请日:2021-06-03
Applicant: SIMON FRASER UNIVERSITY
Inventor: David J. VOCADLO , Robert BRITTON , Yang WANG , Venkata Narasimharao THOTA , Anthony FERS-LIDOU
CPC classification number: C07C35/14 , C07F9/12 , C07H3/02 , C12N5/0682 , C12N2500/30
Abstract: The present invention relates to inhibitors of protein fucosylation. More specifically, the present invention relates to carbacyclic compounds of Formula (I) useful as inhibitors of protein fucosylation, or for treating a cancer, an autoimmune disease, an infectious disease, an inflammatory disease, or sickle cell disease.
-
公开(公告)号:US11684095B2
公开(公告)日:2023-06-27
申请号:US16138864
申请日:2018-09-21
Applicant: Simon Fraser University
Inventor: Daniel Eamon Abram , Farid Golnaraghi , Gaofeng Gary Wang , Combiz Jelveh
IPC: A41D13/015 , A42B3/06 , B32B7/08 , A63B71/08 , A63B71/10 , A63B71/12 , A41D31/18 , A41D13/05 , A41D13/06 , A41D13/08 , A42B3/12 , A42B3/14
CPC classification number: A41D13/015 , A41D13/0506 , A41D13/0512 , A41D13/0518 , A41D13/0531 , A41D13/0543 , A41D13/065 , A41D13/08 , A41D31/185 , A42B3/064 , A42B3/121 , A63B71/08 , A63B71/081 , A63B71/10 , A63B71/12 , A63B71/1225 , A63B71/1291 , B32B7/08 , A41D2600/10 , A41D2600/104 , A42B3/14 , A63B2071/125 , A63B2071/1208 , A63B2071/1233 , A63B2071/1258 , A63B2071/1275 , A63B2071/1283 , A63B2209/10 , B32B2250/04 , B32B2307/56 , B32B2437/04 , B32B2571/00
Abstract: The present disclosure seeks to reduce the effects of rotational and linear acceleration experienced by the body of a user in response to an impact force. Modular disengaging systems of the present disclosure are generally suitable for coupling to protective equipment to provide a disengaging motion between various layers such that the effects of the impact force to the body of the user are reduced. Generally described, the modular disengaging systems of the present disclosure include layers configured to facilitate relative lateral motion therebetween upon an impact force.
-
公开(公告)号:US20220403119A1
公开(公告)日:2022-12-22
申请号:US17869733
申请日:2022-07-20
Applicant: Simon Fraser University
Inventor: David Terence Michael STEVENS , Ajit KHOSLA , Bonnie GRAY , Daniel LEZNOFF , Hidemitsu FURUKAWA
Abstract: A method of immobilization of an insoluble dopant. In some embodiments, the insoluble dopant comprises a coordination polymer. In some embodiments, the insoluble dopant comprises a vapochromic coordination polymer. The method may comprise dissolving a polymer carrier in a solvent. The polymer carrier may comprise a thermoplastic such as, but not limited to, polylactic acid, polyethylene glycol or polycarbonate. The insoluble dopant (e.g. a coordination polymer such as a vapochromic coordination polymer) may then be mixed into the dissolved polymer. Phase separation of the mixture of the dopant and dissolved polymer may be induced to form a hydrogel. The hydrogel may be employed as is (e.g. as a raw material for hydrogel 3D printing, as a sensing material, etc.) or may undergo further processing (e.g. solidification, grinding, extrusion, etc.) before being employed, for example, as a raw material for 3D printing, as a sensing material, etc.
-
公开(公告)号:US20210235698A1
公开(公告)日:2021-08-05
申请号:US17236521
申请日:2021-04-21
Applicant: SIMON FRASER UNIVERSITY
Inventor: Regine M. GRIES , Robert A. BRITTON , Michael T. HOLMES , Gerhard J. GRIES
IPC: A01N43/50 , A01N25/18 , A01M1/02 , A01M1/20 , A01N25/08 , A01N31/02 , A01N31/04 , A01N33/08 , A01N35/02 , A01N35/04 , A01N35/06 , A01N37/02
Abstract: Disclosed is a composition of volatile and less-volatile pheromone components that can be used alone or in combination with other compounds to attract and/or arrest bed bugs of both sexes and all developmental stages. This blend can be used to bait traps that are effective in capturing bed bugs in infested premises or can be combined with a pesticide that is lethal to bed bugs.
-
公开(公告)号:US11048776B2
公开(公告)日:2021-06-29
申请号:US16299120
申请日:2019-03-11
Applicant: Simon Fraser University
Inventor: Mark Snaterse , James Maxwell Donelan , Sung Jae Chang
Abstract: A method is provided for the automatic control of cycling speed in a human. The method comprises: estimating the subject's actual cycling speed using one or more sensors to thereby obtain a measured speed; determining an error comprising a difference between a desired speed and the measured speed; and outputting, to the subject, a stimulus frequency signal wherein the stimulus frequency signal is based on the error in such a manner that when the subject pedals in a manner that matches a frequency of the stimulus frequency signal, the subject's actual speed controllably tracks the desired speed.
-
公开(公告)号:US11025200B2
公开(公告)日:2021-06-01
申请号:US16562337
申请日:2019-09-05
Applicant: Simon Fraser University
Inventor: Zachary Raymond Nunn , Erol Girt
Abstract: A magnetic structure is provided. The magnetic structure may have a first magnetic layer with a first magnetization direction, a second magnetic layer with a second magnetization direction and a coupling layer interposed between the first and second magnetic layers. The coupling layer may include at least one non-magnetic element and at least one magnetic element. The atomic ratio of the at least one non-magnetic element to the at least one magnetic element is (100−x):x, where x is an atomic concentration parameter. Atomic concentration parameter, x, may cause the first magnetic layer to be non-collinearly coupled to the second magnetic layer such that, in the absence of external magnetic field, the first magnetization direction is oriented at a non-collinear angle relative to the second magnetization direction.
-
公开(公告)号:US11015672B2
公开(公告)日:2021-05-25
申请号:US16783221
申请日:2020-02-06
Applicant: SIMON FRASER UNIVERSITY
Inventor: Mohammad Mehdi Naserimojarad , Mehrdad Moallem , Siamak Arzanpour
IPC: B62K25/08 , F16F9/53 , F16F9/19 , B62K25/10 , F16F9/34 , B62K25/28 , F16F9/02 , F16D37/02 , G05G5/03
Abstract: A bicycle with a suspension system for a wheel of the bicycle, the suspension system including a smart fluid damper for dampening a movement of the wheel relative to the frame. The smart fluid damper includes a flow control element disposed within a cavity of the damper and configured to apply a field to a smart fluid within a fluid passage extending through the flow control element. The flow control element includes field barriers proximate the fluid passage to locally block and/or divert the field such that the field cannot pass therethrough. The field barriers are arranged to cause the field to criss-cross the fluid passage at multiple axial intervals along the fluid passage, thereby focusing the field within the fluid passage.
-
公开(公告)号:US20210137184A1
公开(公告)日:2021-05-13
申请号:US16491803
申请日:2018-03-06
Applicant: SIMON FRASER UNIVERSITY
Inventor: Daniel Eamon ABRAM , Farid GOLNARAGHI , Gaofeng Gary WANG
IPC: A41D13/015 , A42B3/12 , A42B3/06 , B32B3/26 , B32B5/18 , B32B5/24 , B32B5/26 , B32B7/12 , B32B7/08 , B32B25/04 , B32B25/08 , B32B25/10 , B32B25/20 , B32B27/06 , B32B27/12 , B32B27/08
Abstract: Generally described, aspects of the disclosed subject matter are directed to impact mitigating membranes. In accordance with aspects of the present disclosure, the impact mitigating membranes generally include a laminar core having a first lamina and a second lamina coupled to the first lamina and configured to shift relative to the first lamina to dissipate kinetic energy resulting from an oblique impact force. The laminar core may include a lubricating layer or self-lubrication between the lamina to reduce friction. In general, the laminar core is surrounded by first and second encapsulating layers positioned adjacent each lamina. An anchoring attachment coupled to one or more of the first and second encapsulating layer and associating with the laminar core constrains relative lateral motion between the laminar core and the first and second encapsulating layers.
-
公开(公告)号:US10895604B2
公开(公告)日:2021-01-19
申请号:US15744470
申请日:2016-07-13
Applicant: Ballard Power Systems Inc. , Simon Fraser University
Inventor: Jacob W. Devaal , Hooman Homayouni , Farid Golnaraghi
IPC: G01R31/389 , G01R31/3835 , G01N27/02 , G01N27/416 , H01M8/1018 , H03L5/00
Abstract: Systems and methods to provide a low voltage interface coupleable between an energy storage device or a DC power source (e.g., fuel cell stack, battery) and one or more AC signal diagnostic systems. The low voltage interface reduces a voltage of the DC power source and supplies the reduced voltage to the one or more AC signal diagnostic systems without affecting the results of the measurements obtained by the one or more AC signal diagnostic systems. Such functionality provides a safer method for performing advanced analysis (e.g., EIS, frequency analysis) while utilizing lower cost and/or smaller components.
-
公开(公告)号:US10800874B2
公开(公告)日:2020-10-13
申请号:US16068654
申请日:2017-01-06
Applicant: Simon Fraser University
Inventor: Steven Holdcroft , Andrew Wright
IPC: C08G61/00 , C08G61/10 , C07D235/18 , B01D67/00 , B01D71/28 , C08J5/22 , C25B11/04 , H01M4/86 , C25B13/08
Abstract: The present disclosure provides alkaline-stable m-terphenyl benzimidazolium hydroxide compounds, in which the C2-position is attached to a phenyl group having various substituents at the ortho positions. Polymers incorporating m-terphenylene repeating groups derived from these alkaline-stable benzimidazolium hydroxide compounds are also presented, along with their inclusion in ionic membranes and in electrochemical devices.
-
-
-
-
-
-
-
-
-