公开(公告)号：US09140605B2

公开(公告)日：2015-09-22

申请号：US14166067

申请日：2014-01-28

Applicant: RAYTHEON COMPANY

Inventor： Ian S. Robinson ,  John D. Bloomer

IPC: G01J3/45 ,  G01J3/28 ,  G01J3/26

CPC classification number: G01J3/2823 ,  G01J3/0237 ,  G01J3/027 ,  G01J3/0294 ,  G01J3/06 ,  G01J3/26 ,  G01J3/45 ,  G01J3/4535 ,  G01J2003/2826

Abstract: An imaging transform spectrometer, and method of operation thereof, that is dynamically configurable “on demand” between an interferometric spectrometer function and a broadband spatial imaging function to allow a single instrument to capture both broadband spatial imagery and spectral data of a scene. In one example, the imaging transform spectrometer is configured such that the modulation used for interferometric imaging may be dynamically turned ON and OFF to select a desired mode of operation for the instrument.

Abstract translation: 成像变换光谱仪及其操作方法，其可以在干涉测量光谱仪功能和宽带空间成像功能之间“按要求”动态配置，以允许单个仪器捕获场景的宽带空间图像和光谱数据。 在一个示例中，成像变换光谱仪被配置为使得用于干涉成像的调制可以被动态地接通和断开以选择仪器的期望的操作模式。

公开(公告)号：US20150260576A1

公开(公告)日：2015-09-17

申请号：US14666249

申请日：2015-03-23

Applicant: MKS Technology (d/b/a Snowy Range Instruments)

Inventor： Mark Watson ,  Shane Buller ,  Keith Carron

IPC: G01J3/44 ,  G01N21/65 ,  G01J3/06

CPC classification number: G01J3/4406 ,  G01J3/06 ,  G01J3/44 ,  G01J2003/062 ,  G01J2003/064 ,  G01N21/65 ,  G01N21/658 ,  G01N33/54313 ,  G01N33/54373 ,  G01N2201/0612

Abstract: A spectrometer is provided. In one implementation, for example, a spectrometer comprises an excitation source, a focusing lens, a movable mirror, and an actuator assembly. The focusing lens is adapted to focus an incident beam from the excitation source. The actuator assembly is adapted to control the movable mirror to move a focused incident beam across a surface of the sample.

Abstract translation: 提供光谱仪。 在一个实施方案中，例如，光谱仪包括激发源，聚焦透镜，可移动反射镜和致动器组件。 聚焦透镜适于聚焦来自激发源的入射光束。 致动器组件适于控制可移动镜以将聚焦的入射光束移动穿过样品的表面。

公开(公告)号：US09103721B2

公开(公告)日：2015-08-11

申请号：US13439951

申请日：2012-04-05

Applicant: Valerica Raicu ,  Gabriel Biener

Inventor： Valerica Raicu ,  Gabriel Biener

IPC: G01J3/00 ,  G01J3/28 ,  G02B21/00 ,  G01J3/02 ,  G01J3/06 ,  G01J3/44 ,  G02B21/16 ,  G02B27/09

CPC classification number: G01J3/2803 ,  G01J3/027 ,  G01J3/0294 ,  G01J3/06 ,  G01J3/4406 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1475 ,  G01N2015/1006 ,  G02B21/002 ,  G02B21/0076 ,  G02B21/16 ,  G02B27/0927 ,  G02B27/0983

Abstract: A system and method of high-speed microscopy using a two-photon microscope with spectral resolution. The microscope is operable to provide two- to five-dimensional fluorescence images of samples, including two or three spatial dimensions, a spectral dimension (for fluorescence emission), and a temporal dimension (on a scale of less than approximately one second). Two-dimensional (spatial) images with a complete wavelength spectrum are generated from a single scan of a sample. The microscope may include one of a multi-beam point scanning microscope, a single beam line scanning microscope, and a multi-beam line scanning microscope. The line scans may be formed using one or more of curved mirrors and lenses. The multiple beams may be formed using one of a grating, an array of lenses, and a beam splitter.

Abstract translation: 使用具有光谱分辨率的双光子显微镜的高速显微镜的系统和方法。 显微镜可操作以提供样品的二维至五维荧光图像，包括两个或三个空间维度，光谱维度（用于荧光发射）和时间维度（小于约一秒的刻度）。 从样品的单次扫描产生具有完整波长谱的二维（空间）图像。 显微镜可以包括多光束点扫描显微镜，单束线扫描显微镜和多光束线扫描显微镜中的一个。 线扫描可以使用一个或多个弯曲镜和透镜来形成。 多个光束可以使用光栅，透镜阵列和分束器中的一个来形成。

公开(公告)号：US08969806B2

公开(公告)日：2015-03-03

申请号：US14129798

申请日：2012-06-27

Applicant: Tomohiro Fukuma

Inventor： Tomohiro Fukuma

IPC: G01N21/95 ,  G01J3/06 ,  G01N21/3563 ,  G01J3/42 ,  G01N21/359 ,  G01N21/85

CPC classification number: G01N21/9508 ,  G01J3/06 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/85

Abstract: A drug inspection device and method for distinguishing tablets that have different amounts of active pharmaceutical ingredients and are indistinguishable in appearance. The device focuses on a tablet packaging process for tablets containing different amounts of active pharmaceutical ingredients, every row or every pocket, having housed therein a plurality of tablets, is used for conveyance. A beam having near-infrared light irradiates the tablets, a spectroscope receives reflected light, a near-infrared imaging unit captures a spectrum obtained through dispersion of the reflected light by the spectroscope and generates image data, and a control unit processes the image data and performs an operation for distinguishing the types of tablets. The control unit controls the near-infrared imaging unit to perform image capture at least once on the tablets included in the one row, to compute average spectrum data per tablet, and to distinguish the type of tablet based on the average spectrum data.

Abstract translation: 一种用于区分具有不同量的活性药物成分并且在外观上难以区分的片剂的药物检查装置和方法。 该装置专注于包含不同量的活性药物成分，每排或每个口袋的片剂的片剂包装方法，其中容纳有多个片剂，用于输送。 具有近红外光的光束照射片剂，分光镜接收反射光，近红外成像单元捕获通过分光镜分散反射光而获得的光谱，并生成图像数据，并且控制单元处理图像数据和 执行区分片剂类型的操作。 控制单元控制近红外成像单元在包括在一行中的平板电脑上至少执行一次图像捕获，以计算每个平板的平均频谱数据，并根据平均频谱数据区分平板电脑的类型。

公开(公告)号：US20150010878A1

公开(公告)日：2015-01-08

申请号：US14372388

申请日：2013-01-18

Applicant: University of Washington Through Its Center for Commercialization

Inventor： Eric J. Seibel ,  Liang Zhang ,  Richard S. Johnston ,  Charles D. Melville ,  Leonard Nelson ,  Cameron M. Lee ,  Joel Berg

IPC: A61B5/00 ,  A61B1/015 ,  A61B1/247 ,  A61B1/00 ,  A61C19/04 ,  A61B1/07

CPC classification number: A61B5/0088 ,  A61B1/00009 ,  A61B1/00096 ,  A61B1/00142 ,  A61B1/015 ,  A61B1/07 ,  A61B1/247 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/4547 ,  A61C19/04 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/06 ,  G01J3/10 ,  G01J3/4406 ,  G01N21/645 ,  G01N21/6486 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2021/6493

Abstract: Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (AF) from multiple excitation wavelengths is obtained and analyzed. Endogenous fluorophores residing in the enamel naturally fluoresce when illuminated by wavelengths ranging from ultraviolet into the visible spectrum. The relative intensities of the AF emission changes between different excitation wavelengths when the enamel changes from healthy to demineralized. By taking a ratio of AF emission spectra integrals between different excitation wavelengths, a standard is created wherein changes in AF ratios within a tooth are quantified and serve as indicators of early stage enamel demineralization. The techniques described herein may be used in conjunction with a scanning fiber endoscope (SFE) to provide a reliable, safe and low-cost means for identifying dental caries or decays.

Abstract translation: 提供了检测早期龋齿和衰老的方法和系统。 特别地，在一个实施例中，获得并分析来自多个激发波长的激光诱导自发荧光（AF）。 当从紫外线到可见光谱的波长照射时，驻留在釉质中的内源性荧光团自然发荧光。 当釉质从健康变为软化时，AF发射的相对强度在不同的激发波长之间变化。 通过采用不同激发波长之间的AF发射光谱积分的比例，创建了一种标准，其中量化牙齿内AF比的变化，并用作早期釉质脱矿质的指标。 本文描述的技术可以与扫描光纤内窥镜（SFE）一起使用，以提供用于识别龋齿或衰变的可靠，安全和低成本的方法。

公开(公告)号：US20140374573A1

公开(公告)日：2014-12-25

申请号：US14270929

申请日：2014-05-06

Applicant: Gonzalo Arce ,  Henry Arguello Fuentes

Inventor： Gonzalo Arce ,  Henry Arguello Fuentes

IPC: G01J3/51 ,  H01L27/146

CPC classification number: H01L27/14625 ,  G01J3/0229 ,  G01J3/06 ,  G01J3/14 ,  G01J3/2823 ,  H01L27/14621

Abstract: Spectral imaging sensors and methods are disclosed. A spectral imaging sensor includes a color-coded array of apertures positioned to receive light from an object to be imaged. The array includes a first plurality of apertures configured to pass light in a first predetermined wavelength range and a second plurality of apertures configured to pass light in a second predetermined wavelength range different from the first predetermined wavelength range. The imaging sensor further includes one or more optical elements positioned to receive light passing through the color-coded array, and a photodetector positioned to receive light from the one of more optical elements. A spectral imaging method includes the steps of filtering light from an object to be imaged through a color-coded array of apertures, redirecting the filtered light with one or more optical elements, and receiving the redirected light with a photodetector.

Abstract translation: 公开了光谱成像传感器和方法。 光谱成像传感器包括定位成接收来自待成像对象的光的孔的颜色编码阵列。 该阵列包括被配置为使第一预定波长范围内的光通过的第一多个孔，以及被配置成使第二预定波长范围内的第一预定波长范围内的光通过的第二多个孔。 成像传感器还包括被定位成接收通过彩色编码阵列的光的一个或多个光学元件，以及定位成接收来自多个光学元件中的一个的光的光电检测器。 光谱成像方法包括以下步骤：通过彩色编码的孔阵列对来自待成像对象的光进行过滤，使用一个或多个光学元件重定向经过滤光，以及用光电检测器接收重定向的光。

公开(公告)号：US20140268135A1

公开(公告)日：2014-09-18

申请号：US13841095

申请日：2013-03-15

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： James A. Cox ,  Daniel Youngner

IPC: G01J3/433

CPC classification number: G01J3/10 ,  G01J3/06 ,  G01J3/14 ,  G01J3/18

Abstract: Stand-off spectrometry systems and methods are described herein. One system includes a laser source configured to emit a single-spectral light, and an optical frequency comb (OFC) coupled to the laser source and configured to generate, using the single-spectral light, a multi-spectral light to determine an absorption spectrum of a substance.

Abstract translation: 本文描述了分离光谱测定系统和方法。 一个系统包括被配置为发射单光谱光的激光源和耦合到激光源的光频梳（OFC），并被配置为使用单光谱光产生多光谱以确定吸收光谱 的物质

公开(公告)号：US20140193078A1

公开(公告)日：2014-07-10

申请号：US14090753

申请日：2013-11-26

Applicant: Raytheon Company

Inventor： Ian S. Robinson ,  Bradley Flanders

IPC: G06K9/46

CPC classification number: G06K9/46 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/06 ,  G01J3/2823 ,  G01J2003/2836 ,  G06K9/0063

Abstract: A method for reducing dimensionality of hyperspectral images includes receiving a hyperspectral image having a plurality of pixels. The method may further include establishing an orthonormal basis vector set comprising a plurality of mutually orthogonal normalized members. Each of the mutually orthogonal normalized members may be associated with one of the plurality of pixels of the hyperspectral image. The method may further include decomposing the hyperspectral image into a reduced dimensionality image, utilizing calculations performed while establishing said orthonormal basis vector set. A system configured to perform the method may also be provided.

Abstract translation: 一种用于降低高光谱图像的维数的方法包括接收具有多个像素的高光谱图像。 该方法还可以包括建立包括多个相互正交的归一化成员的正交基矢量集合。 每个相互正交的标准化构件可以与高光谱图像的多个像素中的一个相关联。 该方法可以进一步包括利用在建立所述正交基本向量集合时执行的计算来将高光谱图像分解为降维的图像。 还可以提供被配置为执行该方法的系统。

公开(公告)号：US20140190243A1

公开(公告)日：2014-07-10

申请号：US13980354

申请日：2011-09-30

Applicant: Masahide Gunji

Inventor： Masahide Gunji

IPC: G01J3/44

CPC classification number: G01J3/4406 ,  G01J3/06 ,  G01J3/18 ,  G01J3/42 ,  G01N21/64 ,  G01N30/74 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6421

Abstract: A fluorescence spectrophotometer according to the present invention includes: a light source 1; a sample cell 3; an excitation-side light-dispersing system 2 for dispersing a light from the light source 1 and for casting a desired wavelength of light into the sample cell 3; an emission-side light-dispersing system 4 for dispersing a light emitted from the sample cell 3, the emission-side light-dispersing system 4 being located off an optical path of a transmitted light exiting from the sample cell 3 after being cast from the excitation-side light-dispersing system 2 into the sample cell 3; and a photodetector 5 capable of detecting, among the light from the emission-side light-dispersing system 4, an emission light having the same wavelength as the light cast from the excitation-side light-dispersing system 2 into the sample cell 3.

Abstract translation: 根据本发明的荧光分光光度计包括：光源1; 样品池3; 用于分散来自光源1的光并将期望波长的光投射到样品池3中的激发侧光分散系统2; 用于分散从样品池3发射的光的发射侧光分散系统4，发射侧光分散系统4从从样品池3射出的透射光的光路上离开 激发侧光分散系统2进入样品池3; 以及光检测器5，其能够从发光侧光分散系统4的光中检测与从激发侧光分散系统2投射到样品池3中的光的相同波长的发射光。

公开(公告)号：US20140169706A1

公开(公告)日：2014-06-19

申请号：US14133174

申请日：2013-12-18

Applicant: Thermo Electron Scientific Instruments LLC

Inventor： John R. IVERSON

IPC: F16C33/16 ,  F16C29/02

CPC classification number: F16C33/16 ,  F16C29/02 ,  G01J3/0202 ,  G01J3/06 ,  G01J3/4535

Abstract: An all-graphite interferometer bearing assembly is introduced that allows the movement of a movable mirror in a Michelson interferometer without degradation during use. The assembly includes a stationary hollow graphite tube and a movable assembly which includes a mirror and a monolithic graphite member slidably disposed within the bore of the graphite tube that is composed of the same grade of graphite material as the monolithic graphite member. The result is a robust novel moving mirror arrangement in a Michelson interferometer that enables precise mirror alignment control, a long stroke length, excellent vibration damping and reduced sensitivity to external vibrations.

Abstract translation: 引入了全石墨干涉仪轴承组件，其允许在迈克尔逊干涉仪中移动可移动镜而不会在使用过程中退化。 组件包括固定的中空石墨管和可移动组件，其包括反射镜和可滑动地设置在石墨管的孔内的整体石墨构件，该石墨管由与整体式石墨构件相同等级的石墨材料组成。 结果是在迈克尔逊干涉仪中采用了坚固的新型移动反射镜装置，能够进行精确的镜面对准控制，长行程长度，优异的振动阻尼和对外部振动的灵敏度降低。