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公开(公告)号：US08348867B2
公开(公告)日：2013-01-08
申请号：US12467234
申请日：2009-05-15
IPC分类号： A61H1/00
CPC分类号： A61N7/00 , A61B2017/00747 , A61B2017/22008 , A61K9/0009 , A61K41/0028 , A61M37/0092 , A61M2037/003 , A61N1/0412 , A61N1/0492 , A61N1/327 , A61N2007/0008 , A61N2007/0039
摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.
摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。
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公开(公告)号：US08298578B2
公开(公告)日：2012-10-30
申请号：US13252942
申请日：2011-10-04
申请人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
发明人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
CPC分类号： G01N33/558 , A61F9/0017 , A61K9/0048 , A61K9/0051 , A61K31/57 , A61K31/573 , A61K31/58 , A61K38/385 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2039/505 , C07K16/22 , C07K2317/24 , C07K2317/55 , Y10T29/49826
摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
摘要翻译： 用于释放治疗剂的治疗装置包括联接到包括储存器的容器的多孔结构。 储存器包括体积大小，当耦合到多孔结构并且植入患者体内时，释放治疗剂量的治疗剂延长的时间。 所述多孔结构可以包括联接到所述储存器的第一侧和与所述患者联接以释放所述治疗剂的第二侧。 多个互连通道可以从第一侧延伸到第二侧，以便将第一侧上的第一多个开口与第二侧上的第二多个开口连接。
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公开(公告)号：US20120029445A1
公开(公告)日：2012-02-02
申请号：US13252998
申请日：2011-10-04
申请人： Eugene de Juan, JR. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
发明人： Eugene de Juan, JR. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
CPC分类号： G01N33/558 , A61F9/0017 , A61K9/0048 , A61K9/0051 , A61K31/57 , A61K31/573 , A61K31/58 , A61K38/385 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2039/505 , C07K16/22 , C07K2317/24 , C07K2317/55 , Y10T29/49826
摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
摘要翻译： 用于释放治疗剂的治疗装置包括联接到包括储存器的容器的多孔结构。 储存器包括体积大小，当耦合到多孔结构并且植入患者体内时，释放治疗剂量的治疗剂延长的时间。 所述多孔结构可以包括联接到所述储存器的第一侧和与所述患者联接以释放所述治疗剂的第二侧。 多个互连通道可以从第一侧延伸到第二侧，以便将第一侧上的第一多个开口与第二侧上的第二多个开口连接。
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公开(公告)号：US08038672B2
公开(公告)日：2011-10-18
申请号：US11472630
申请日：2006-06-21
申请人： William Malecki , Dan Francis , Kenneth Horne , Mark E. Deem , Hanson S. Gifford, III , Jose Alejandro
发明人： William Malecki , Dan Francis , Kenneth Horne , Mark E. Deem , Hanson S. Gifford, III , Jose Alejandro
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/083 , A61B17/10 , A61B18/1477 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/0061 , A61B2017/00615 , A61B2017/00623 , A61B2017/00668 , A61B2017/00867 , A61B2017/0641 , A61B2017/0645 , A61B2017/0649 , A61B2018/00011 , A61B2018/00214 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00619 , A61B2018/0063 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/1425 , A61B2018/1472 , A61B2090/3614 , A61N7/022 , C08L2201/12
摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.
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公开(公告)号：US07967833B2
公开(公告)日：2011-06-28
申请号：US10941661
申请日：2004-09-15
申请人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John H. Stevens , William S. Peters
发明人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John H. Stevens , William S. Peters
IPC分类号： A61B17/00
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0467 , A61B17/0469 , A61B17/06061 , A61B17/064 , A61B17/068 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B17/2909 , A61B17/30 , A61B17/3403 , A61B18/1442 , A61B18/1492 , A61B90/50 , A61B2017/00243 , A61B2017/00247 , A61B2017/00637 , A61B2017/00663 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/306 , A61B2017/3405 , A61B2017/3427 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2090/064 , A61F2/2427 , A61F2/2496 , A61M1/3664 , A61M25/0023 , A61M25/0032 , A61M25/1011 , A61M39/0247 , A61M2025/0003 , A61M2025/028 , A61M2025/1052 , A61M2039/027 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , A61M2210/127 , A61M2230/005
摘要： The invention provides devices and methods for performing closed-chest surgical intervention within an internal cavity of a patient's heart or great vessel. A scope extending through a percutaneous intercostal penetration in the patient's chest is used to view an internal portion of the patient's chest. An internal penetration is formed in a wall of the heart or great vessel using cutting means introduced through a percutaneous penetration in an intercostal space in the patient's chest. An interventional tool is inserted through the internal penetration to perform a surgical procedure under visualization using the scope. A cutting tool is introduced into the patient's left atrium from a right portion of the patient's chest to remove the patient's mitral valve. A replacement valve is then introduced through an intercostal space in the right portion of the chest and through the internal penetration in the heart, and the replacement valve is attached in the mitral valve position.
摘要翻译： 本发明提供了用于在患者的心脏或大容器的内腔内执行闭胸手术干预的装置和方法。 使用延伸穿过患者胸部经皮肋间穿透的范围来观察患者胸部的内部部分。 使用通过在患者胸部的肋间空间经皮渗透引入的切割装置在心脏或大容器的壁上形成内部穿透。 通过内部穿透插入介入工具，以使用范围进行可视化的外科手术。 从患者胸部的右侧部分向患者的左心房引入切割工具以移除患者的二尖瓣。 然后将置换瓣膜通过胸部右侧部分的肋间空间并通过心脏内部穿透引入，置换瓣膜连接于二尖瓣位置。
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公开(公告)号：US07967763B2
公开(公告)日：2011-06-28
申请号：US11292950
申请日：2005-12-02
IPC分类号： A61H1/00
CPC分类号： A61N7/00 , A61B2017/00747 , A61B2017/22008 , A61K9/0009 , A61K41/0028 , A61M37/0092 , A61M2037/003 , A61N1/0412 , A61N1/0492 , A61N1/327 , A61N2007/0008 , A61N2007/0039
摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.
摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。
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公开(公告)号：US07854228B2
公开(公告)日：2010-12-21
申请号：US11092123
申请日：2005-03-28
申请人： Peter M. Wilson , Antony J. Fields , Hanson S. Gifford, III , John G. McCutcheon , Michael J. Hendricksen , Alan R. Rapacki , David R. Tholfsen , Michael S. Barrett , Ronald Hundertmark , Douglas Sutton
发明人： Peter M. Wilson , Antony J. Fields , Hanson S. Gifford, III , John G. McCutcheon , Michael J. Hendricksen , Alan R. Rapacki , David R. Tholfsen , Michael S. Barrett , Ronald Hundertmark , Douglas Sutton
CPC分类号： A61F2/2412 , A61B2017/1205 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2002/9522 , Y10S128/912
摘要： Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway and includes a valve protector that at least partially surrounds a valve member. The valve protector has sufficient rigidity to maintain the shape of the valve member against compression.
摘要翻译： 描述了患者肺容积减少的方法和系统。 所述方法包括在肺的支气管通道中植入流量控制装置。 流量控制装置调节通过支气管通道的流体流动并且包括至少部分地围绕阀构件的阀保护器。 阀保护器具有足够的刚性以保持阀构件的形状不被压缩。
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公开(公告)号：US20100010420A1
公开(公告)日：2010-01-14
申请号：US12559448
申请日：2009-09-14
IPC分类号： A61M37/00
CPC分类号： A61N7/00 , A61B2017/00747 , A61B2017/22008 , A61K9/0009 , A61K41/0028 , A61M37/0092 , A61M2037/003 , A61N1/0412 , A61N1/0492 , A61N1/327 , A61N2007/0008 , A61N2007/0039
摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.
摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。
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39.发明申请公开(公告)号：US20090270975A1
公开(公告)日：2009-10-29
申请号：US12386500
申请日：2009-04-17
申请人： Hanson S. Gifford, III , Ivan Sepetka , Mark E. Deem , Douglas S. Sutton , Allan R. Will , Martin S. Dieck , Sunmi Chew
发明人： Hanson S. Gifford, III , Ivan Sepetka , Mark E. Deem , Douglas S. Sutton , Allan R. Will , Martin S. Dieck , Sunmi Chew
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/0095 , A61F2/013 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2/97 , A61F2002/018 , A61F2002/061 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2002/9511 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/0098
摘要： A liner is advanced through a narrowed region in a vessel such as the internal carotid artery. The liner is advanced through the narrowed region in a collapsed position. A stent is then advanced through the liner and expanded to open the narrowed region. The liner may also have an anchor which expands an end of the liner before the stent is introduced.
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公开(公告)号：US07357812B2
公开(公告)日：2008-04-15
申请号：US10966806
申请日：2004-10-14
申请人： Bernard Andreas , Ron French , Mark E. Deem , Hanson S. Gifford, III , Alan Will
发明人： Bernard Andreas , Ron French , Mark E. Deem , Hanson S. Gifford, III , Alan Will
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61B1/00151 , A61F2/966 , A61F2002/9517 , Y10S623/903
摘要： Blood vessels and other body lumens are expanded using an evertible braided prosthesis. The braided prosthesis is delivered to the blood vessel in a radially collapsed configuration. A leading edge of the braided prosthesis is then everted so that it expands as it is advanced through the blood vessel. Optionally, the prosthesis can be provided with a biologically active substance in order to inhibit hyperplasia or have other desired biological effects.
摘要翻译： 使用可逆的编织假体扩张血管和其他体腔。 编织的假体以径向收缩的构型输送到血管。 然后，编织假体的前缘被转动，使得它在其通过血管前进时膨胀。 任选地，假体可以具有生物活性物质，以便抑制增生或具有其它所需的生物效应。
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