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公开(公告)号：US20180093020A1
公开(公告)日：2018-04-05
申请号：US15832450
申请日：2017-12-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , Syed F.A. Hossainy , Mikael Trollsas , Stephen D. Pacetti
CPC classification number: A61L31/148 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2420/02 , A61L2420/08 , C08L67/04
Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.
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公开(公告)号：US09763818B2
公开(公告)日：2017-09-19
申请号：US14085716
申请日：2013-11-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
IPC: A61F2/958 , A61F2/91 , A61L27/00 , A61L31/06 , A61F2/86 , A61F2/844 , B29C35/08 , A61L31/14 , A61F2/89 , A61F2/82 , A61F2/915 , A61F2/95 , B29K67/00 , B29L23/00 , B29L31/00
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures.
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公开(公告)号：US09585778B2
公开(公告)日：2017-03-07
申请号：US14333344
申请日：2014-07-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John E. Papp , Syed Faiyaz Ahmed Hossainy , Michael Ngo , Chad Abunassar , Boris Anukhin , Mikael Trollsas , Lewis B. Schwartz
CPC classification number: A61F2/915 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/826 , A61F2002/9155 , A61F2002/91591 , A61F2210/00 , A61F2230/0013 , A61F2230/0054 , A61F2240/001 , B29C35/0805 , B29C65/64 , B29C66/1248 , B29C66/71 , B29C2035/0838 , B29K2067/046 , B29K2995/006 , B29L2031/7534
Abstract: Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed.
Abstract translation: 公开了由具有重叠端环的断开的支架段组成的分段支架。 还公开了具有至少一个不连续链节的支架。
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公开(公告)号：US20170042816A1
公开(公告)日：2017-02-16
申请号：US15242403
申请日：2016-08-19
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , John Stankus , James Su , Syed Hossainy , Joshua Takeshi Smith , Shadid Askar
CPC classification number: A61K9/146 , A61K9/0019 , A61K9/06 , A61K9/08 , A61K38/215 , A61K47/10 , A61K2039/505 , C07K16/241 , C07K16/40 , C07K2317/21
Abstract: Formulations and methods are disclosed which provide controlled, sustained release of a biologic therapeutic to a space within the body. More specifically, formulations comprising a plurality of hydrophilic polymer strands, and methods of forming and administering such formulations, are disclosed. In some embodiments, the formulations exhibit a burst release, an initial release, a triphasic release, and release over thirty to ninety days of the biologic therapeutic. In some embodiments, the formulations exhibit reversible precipitation of the biologic therapeutic into precipitates having a diameter of about 50 nm to about 10 μm.
Abstract translation: 公开了提供对体内空间的生物治疗剂的受控的持续释放的制剂和方法。 更具体地，公开了包含多个亲水性聚合物链的制剂，以及形成和施用这些制剂的方法。 在一些实施方案中，制剂在生物治疗的三十至九十天内显示爆发释放，初始释放，三相释放和释放。 在一些实施方案中，制剂将生物治疗剂的可逆沉淀显示为具有约50nm至约10μm直径的沉淀物。
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公开(公告)号：US09517150B2
公开(公告)日：2016-12-13
申请号：US13842432
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Mikael Trollsas , Michael Huy Ngo , Erik David Eli
CPC classification number: A61F2/915 , A61F2/958 , A61F2002/91575 , A61F2210/0004 , A61F2230/0054 , A61F2240/00 , A61F2240/008 , A61F2250/0071 , A61L31/06 , B29C55/24 , B29C55/26 , B29C69/001 , B29L2031/753 , Y10T29/49 , Y10T29/49927 , C08L67/04
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架具有当植入在外周血管内时产生较低的晚期管腔损失并且也表现出高的轴向疲劳寿命的结构。 在优选实施例中，支架形成通过连杆互连的环形结构，其中环具有12个冠部，并且至多两个连接相邻环件的连杆。
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Patent Agency Ranking
36.发明授权公开(公告)号：US09510976B2
公开(公告)日：2016-12-06
申请号：US14265343
申请日：2014-04-29
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Syed Hossainy , Paul Consigny , Dariush Davalian , James Su , Michael Ngo , Adrain Gale , Jesus Magana , Mikael Trollsas , Evan Norton , Benjamyn Serna
CPC classification number: A61F2/958 , A61B1/06 , A61F2/915 , A61F11/002 , A61F2002/91575 , A61F2002/91583 , A61F2230/0067 , A61F2250/0018 , A61F2250/0026 , A61F2250/0046 , A61F2250/0048 , A61F2250/005 , A61F2250/0082 , A61M25/10 , A61M29/02 , A61M2025/105 , A61M2025/1059 , A61M2210/0675
Abstract: A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure.
Abstract translation: 可以植入聚合物支架以治疗咽鼓管。 支架可以设计成具有长度依赖的径向强度，以允许其保持在咽鼓管内并允许正常的关闭和打开咽鼓管。 可以使用气囊来植入支架，并且可以用治疗剂涂覆气囊。 在气球窦扩张过程中，涂覆的气囊也可以用于将治疗剂转移到窦腔。
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公开(公告)号：US09452138B2
公开(公告)日：2016-09-27
申请号：US14142651
申请日：2013-12-27
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , John Stankus , James Su , Syed Hossainy , Joshua Takeshi Smith , Shadid Askar
IPC: A61K38/00 , A61K9/14 , A61K9/00 , A61K47/10 , A61K9/08 , C07K16/24 , C07K16/40 , A61K38/21 , A61K39/00
CPC classification number: A61K9/146 , A61K9/0019 , A61K9/06 , A61K9/08 , A61K38/215 , A61K47/10 , A61K2039/505 , C07K16/241 , C07K16/40 , C07K2317/21
Abstract: Formulations and methods are disclosed which provide controlled, sustained release of a biologic therapeutic to a space within the body. More specifically, formulations comprising a plurality of hydrophilic polymer strands, and methods of forming and administering such formulations, are disclosed. In some embodiments, the formulations exhibit a burst release, an initial release, a triphasic release, and release over thirty to ninety days of the biologic therapeutic. In some embodiments, the formulations exhibit reversible precipitation of the biologic therapeutic into precipitates having a diameter of about 50 nm to about 10 μm.
Abstract translation: 公开了提供对体内空间的生物治疗剂的受控的持续释放的制剂和方法。 更具体地，公开了包含多个亲水性聚合物链的制剂，以及形成和施用这些制剂的方法。 在一些实施方案中，制剂在生物治疗的三十至九十天内显示爆发释放，初始释放，三相释放和释放。 在一些实施方案中，制剂将生物治疗剂的可逆沉淀显示为具有约50nm至约10μm直径的沉淀物。
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公开(公告)号：US20160184491A1
公开(公告)日：2016-06-30
申请号：US15063367
申请日：2016-03-07
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Mikael Trollsas , Lothar Walter Kleiner
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/416 , A61L2420/02 , A61L2420/04 , B05D3/14 , C08F14/22 , C08F114/22 , C08F214/22 , C08F214/28
Abstract: Provided herein is a prohealing piezoelectric coating and the method of making and using the same.
Abstract translation: 本文提供了一种预热压电涂层及其制造和使用方法。
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公开(公告)号：US20160030212A1
公开(公告)日：2016-02-04
申请号：US14880905
申请日：2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John Stankus , Yunbing Wang , Mikael Trollsas , Syed Faiyaz Ahmed Hossainy , Michael H. Ngo , Dariush Davalian
IPC: A61F2/915
CPC classification number: A61F2/915 , A61F2210/0004 , A61F2210/0057 , A61F2230/0013 , A61F2230/0054 , A61L31/041 , A61L31/129 , A61L31/141 , A61L31/148
Abstract: Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component.
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公开(公告)号：US20160000985A1
公开(公告)日：2016-01-07
申请号：US14322826
申请日：2014-07-02
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Paul Consigny , Erik Eli , Stephen D. Pacetti , Mikael Trollsas , John Stankus
IPC: A61M1/30
CPC classification number: A61M1/3655 , A61B2017/1107 , A61B2017/1135
Abstract: A medical device includes a curved tubular body configured for being used as an extravascular device to support vein maturation following the formation of an arteriovenous fistula. The tubular body is curved. The tubular body has an entrance angle of less than about 40 degrees to improve blood flow from the artery into the vein. And the tubular body includes a cuff or edge at the proximal end to stabilize the tubular body at the fistula.
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