公开(公告)号：US20190174025A1

公开(公告)日：2019-06-06

申请号：US16267706

申请日：2019-02-05

Applicant: Nobuyuki SATOH ,  Yasuyuki SUZUKI ,  Masato KOBAYASHI ,  Suguru YOKOZAWA ,  Tatsuhiko OKADA ,  Mamoru YORIMOTO ,  Daisaku HORIKAWA ,  Yuichi SAKURADA

Inventor： Nobuyuki SATOH ,  Yasuyuki SUZUKI ,  Masato KOBAYASHI ,  Suguru YOKOZAWA ,  Tatsuhiko OKADA ,  Mamoru YORIMOTO ,  Daisaku HORIKAWA ,  Yuichi SAKURADA

IPC: H04N1/60 ,  H04N1/028 ,  H04N1/00 ,  G01J3/06 ,  G01J3/02 ,  G01J3/52 ,  H04N5/225 ,  H04N1/41 ,  G06K15/02 ,  G01J3/46

CPC classification number: H04N1/6033 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/46 ,  G01J3/52 ,  G01J3/524 ,  G06K15/027 ,  G06K15/102 ,  G06K2215/0094 ,  G06K2215/101 ,  H04N1/00005 ,  H04N1/00015 ,  H04N1/00023 ,  H04N1/00034 ,  H04N1/00045 ,  H04N1/00047 ,  H04N1/00068 ,  H04N1/00087 ,  H04N1/00278 ,  H04N1/00323 ,  H04N1/0282 ,  H04N1/034 ,  H04N1/41 ,  H04N1/50 ,  H04N1/6008 ,  H04N1/6044 ,  H04N5/2253 ,  H04N5/2254 ,  H04N2201/0082

Abstract: An image capturing unit includes a sensor unit that image-captures a predetermined area including a subject; and a reference chart unit that is arranged in the predetermined area and captured with the subject by the sensor unit.

公开(公告)号：US10302490B2

公开(公告)日：2019-05-28

申请号：US15320567

申请日：2015-06-19

Applicant: Carl Zeiss Microscopy GmbH

Inventor： Burkhard Roscher ,  Stefan Wilhelm ,  Gunter Moehler

IPC: G01J3/06 ,  G01J3/12 ,  G01J3/18 ,  G01J3/28 ,  G02F1/11 ,  G02F1/33 ,  H01S3/00 ,  G02B21/00 ,  G02B21/16

Abstract: A method and apparatus for actuating an acousto-optical component for manipulating light passing therethrough, in particular for manipulating the illumination and/or detection light in the beam path of a microscope, preferably a laser scanning microscope, where the illumination and/or detection wavelength is adjusted by means of at least one frequency generator connected to the acousto-optical component and controlling the manipulation, the frequency generator generates a signal which generates a spectral spread for the intensity distribution of the wavelength of the illumination and/or detection light for ensuring a temperature-independent manipulation. Actuation is effected by two or more actuation signals in such a way that two or more overlapping and/or superposing main lobes of the transfer function of the acousto-optical component or main maxima are generated.

公开(公告)号：US20190033134A1

公开(公告)日：2019-01-31

申请号：US16077578

申请日：2017-02-10

Applicant: OXFORD UNIVERSITY INNOVATION LIMITED

Inventor： Elion Poem ,  Ian Walmsley

IPC: G01J3/32 ,  G01J3/02 ,  G01J3/06 ,  G01J3/28

Abstract: A spectrometer for temporally separating electromagnetic radiation (10) includes a cavity (105) having first and second reflecting mirrors (1, 2, 4, 5). The first mirror (1, 2) has an aperture (8) arranged to allow electromagnetic radiation (10) to be input into the cavity (105). The spectrometer also includes an imaging device (3) between the first and second mirrors (1, 2, 4, 5) that defines an optical axis of the cavity (105) and performs spatial Fourier transforms of the electromagnetic radiation (10). The first and/or second mirrors (1, 2, 4, 5) has a normal that is arranged at a non-parallel angle to the optical axis, such that the position and/or angle of incidence of electromagnetic radiation (10) on the second mirror is shifted after each round trip. The second mirror (4, 5) allows a wavelength component (14) of the electromagnetic radiation to be output from the cavity (105) when the position and/or angle of incidence of the electromagnetic radiation on the second mirror (4) after one or more round trips of the cavity (105) exceeds a threshold.

公开(公告)号：US10161790B2

公开(公告)日：2018-12-25

申请号：US15768714

申请日：2017-08-10

Applicant: Shenzhen Institute of Terahertz Technology and Innovation ,  Shenzhen Terahertz System Equipment Co., Ltd.

Inventor： Qing Ding ,  Shichang Peng ,  Yi Pan ,  Chen Li

IPC: G01J3/02 ,  G01J3/06 ,  G01N21/3586 ,  G01J3/42

Abstract: A delay line device and a terahertz time-domain spectrometer system include: a baseplate, a slide rail component, in which the slide rail component includes a slide, a reflector, a grating ruler component, and an electric-magnetic induction component. When the electric-magnetic component, after being applied a current, cuts the magnetic induction coil to generate power to push the slide moving, the grating ruler component placed on the slide rail component collects the movement information of the slide. The slide's movement drives the reflector placed on the slide to move together to change the optical distance of a pump light, so as to generate the delay between the pump light and a probe light.

公开(公告)号：US10088428B2

公开(公告)日：2018-10-02

申请号：US15309732

申请日：2015-05-08

Applicant: Danmarks Tekniske Universitet

Inventor： Anders Kristensen ,  Christoph Vannahme ,  Martin Dufva

IPC: G01N21/77 ,  H01S3/08 ,  G01J3/08 ,  G01J3/18 ,  G01J3/28 ,  G01N21/41 ,  G01J3/02 ,  G01J3/06

Abstract: A surface refractive index acquisition system for characterization of a sample is provided. The system comprises a grating device configured to receive the sample, and first and second grating regions. First and second grating periods are selected to provide optical resonances for light respectively in first and second wavelength bands. A light source is configured to illuminate part of the first and second grating regions simultaneously. An imaging system is configured to image light from the grating device and comprises an optical element focusing light in a transverse direction and being invariant in an orthogonal transverse direction, the optical element being oriented such that the longitudinal direction of the grating device is oriented to coincide with the invariant direction of the optical element, and an imaging spectrometer comprising an entrance slit having a longitudinal direction oriented to coincide with the invariant direction of the optical element.

公开(公告)号：US10078013B2

公开(公告)日：2018-09-18

申请号：US15723103

申请日：2017-10-02

Applicant: UNIVERSITY OF MARYLAND BALTIMORE COUNTY

Inventor： Bradley Arnold ,  Christopher Cooper ,  John Cataldi

IPC: G01J3/28 ,  G01J3/44 ,  G01J3/18 ,  G02B6/32 ,  G01J3/06 ,  G02B5/18

CPC classification number: G01J3/44 ,  G01J3/0221 ,  G01J3/06 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/36 ,  G02B5/1814 ,  G02B5/1861 ,  G02B6/32

Abstract: The invention provides methods and apparatus comprising a multi-wavelength laser source that uses a single unfocused pulse of a low intensity but high power laser over a large sample area to collect Raman scattered collimated light, which is then Rayleigh filtered and focused using a singlet lens into a stacked fiber bundle connected to a customized spectrograph, which separates the individual spectra from the scattered wavelengths using a hybrid diffraction grating for collection onto spectra-specific sections of an array photodetector to measure spectral intensity and thereby identify one or more compounds in the sample.

公开(公告)号：US20180252578A1

公开(公告)日：2018-09-06

申请号：US15905925

申请日：2018-02-27

Applicant: Shuichi Suzuki ,  Hidetaka Noguchi ,  Masayuki Fujishima ,  Hidenori Kato ,  Junichi Azumi ,  Masashi Suematsu

Inventor： Shuichi Suzuki ,  Hidetaka Noguchi ,  Masayuki Fujishima ,  Hidenori Kato ,  Junichi Azumi ,  Masashi Suematsu

IPC: G01J3/02 ,  G01J3/06 ,  G01J3/30

CPC classification number: G01J3/021 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/06 ,  G01J3/18 ,  G01J3/28 ,  G01J3/30 ,  G01J3/453 ,  G01J3/52 ,  G01J2003/064 ,  G01J2003/451

Abstract: A spectrum measuring device including a ribbon element, a light detection element, and circuitry. The ribbon element includes a first light reflector including a plurality of first light reflection surfaces configured to be translated in an out-of-plane direction, and a second light reflector including a plurality of second light reflection surfaces that are fixed. The circuitry supplies a drive signal to the ribbon element in such a manner that a change of a displacement amount difference between the first light reflection surfaces and the second light reflection surfaces corresponds to a predetermined frequency; and acquires the light quantity data detected by the light detection element at a predetermined sampling frequency.

公开(公告)号：US20180231416A1

公开(公告)日：2018-08-16

申请号：US15320567

申请日：2015-06-19

Applicant: Carl Zeiss Microscopy GmbH

Inventor： Burkhard ROSCHER ,  Stefan WILHELM ,  Gunter MOEHLER

IPC: G01J3/12 ,  G02B21/00 ,  G02F1/11 ,  G01J3/06

CPC classification number: G01J3/1256 ,  G01J3/06 ,  G02B21/002 ,  G02B21/16 ,  G02F1/113 ,  G02F1/116 ,  G02F2203/21

Abstract: A method and apparatus for actuating an acousto-optical component for manipulating light passing therethrough, in particular for manipulating the illumination and/or detection light in the beam path of a microscope, preferably a laser scanning microscope, where the illumination and/or detection wavelength is adjusted by means of at least one frequency generator connected to the acousto-optical component and controlling the manipulation, the frequency generator generates a signal which generates a spectral spread for the intensity distribution of the wavelength of the illumination and/or detection light for ensuring a temperature-independent manipulation. Actuation is effected by two or more actuation signals in such a way that two or more overlapping and/or superposing main lobes of the transfer function of the acousto-optical component or main maxima are generated.

公开(公告)号：US09909923B2

公开(公告)日：2018-03-06

申请号：US14845980

申请日：2015-09-04

Applicant: Sean Xiaolu Wang ,  Qun Li

Inventor： Sean Xiaolu Wang ,  Qun Li

IPC: G01J3/443 ,  G01J3/10 ,  G01J3/02 ,  G01J3/06 ,  G01J3/28

CPC classification number: G01J3/443 ,  G01J3/0208 ,  G01J3/06 ,  G01J3/10 ,  G01J3/28

Abstract: This invention discloses a laser induced breakdown spectroscopy (LIBS) apparatus based on a high repetition rate pulsed laser. The laser produces a train of laser pulses at a high repetition rate in the kHz or even higher range. When the laser beam hits the sample, it generates several thousands of micro-plasmas per second. Synchronized miniature CCD array optical spectrometer modules collect the LIBS signal from these micro-plasmas. By adjusting the integration time of the spectrometer to cover a plurality of periods of the laser pulse train, the spectrometer integrates the LIBS signal produced by this plurality of laser pulses. Hence the intensity of the obtained LIBS spectrum can be greatly improved to increase the signal-to-noise ratio (SNR) and lower the limit of detection (LOD). In addition, the influence of pulse to pulse variation of the laser is minimized since the obtained LIBS spectrum is the spectrum of a plurality of micro-plasmas produced by a plurality of laser pulses. The high repetition rate laser also makes it possible for fast scanning the laser beam over the sample surface such that an average spectrum of the sample is collected to overcome the sample non-uniformity issue or for performing spectral imaging of the sample by correlating the obtained LIBS spectrum with the position of the scanning laser beam.

公开(公告)号：US09778106B2

公开(公告)日：2017-10-03

申请号：US14794316

申请日：2015-07-08

Applicant: TECAN Trading AG

Inventor： Lutz Niggl ,  Andreas Erlbacher ,  Frank Münchow

IPC: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01N35/02 ,  G01N21/25 ,  G01N21/31 ,  G01J3/12

CPC classification number: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01J2003/1204 ,  G01J2003/1213 ,  G01J2003/1217 ,  G01N21/253 ,  G01N21/31 ,  G01N35/028 ,  G01N2021/3174 ,  G01N2201/084

Abstract: A spectrometer (1) comprises a light source (2), a monochromator (3) with at least one diffraction grating (4), a monochromator housing (5), an order sorting filter (7), a microplate receptacle (12) and a controller (6). The order sorting filter (7) of the spectrometer (1) comprises a substrate (23), a first optical thin film (24) and a second optical thin film (25), wherein, in a spatially partly overlapping and interference-free manner, the first optical thin film (24) is arranged on a first surface (26) and the second optical thin film (25) is arranged on a second surface (27) of the substrate (23). A spectrometer (1) equipped with a respective order sorting filter is used in a scanning method for detecting the absorption spectrum of samples examined in wells (14) of microplates (13).