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    Method and apparatus for analyte measurement test time
    21.
    发明申请
    Method and apparatus for analyte measurement test time 审中-公开
    用于分析物测量测试时间的方法和设备

    公开(公告)号：US20080214917A1

    公开(公告)日：2008-09-04

    申请号：US12056017

    申请日：2008-03-26

    申请人： Dirk Boecker

    发明人： Dirk Boecker

    IPC分类号： A61B5/1468 ,  A61B5/151

    CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/15016 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150427 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150916 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15176 ,  A61B5/15182

    摘要： A method is provided for analyte measurement by a user using an analyte measurement device. An analyte measurement is provided with a plurality of penetrating members and analyte sensors. Each analyte sensor is positioned in a sample chamber with a volume no greater than 1 μl. Each sample chamber has a working electrode, reference electrode and a counter electrode. The working electrode has a conductor, an enzyme and a mediator. A penetrating member and an unused analyte detecting member are presented into an active position. The following steps are then performed: (a) the penetrating member is fired to prick the skin and bring a fluid sample to the analyte detecting member, (b) the analyte level is measured, and (c) it takes no more than 10 seconds from the step of presenting the penetrating members and unused analyte into the active position through the step of measuring the analyte level.

    摘要翻译： 提供了一种用户使用分析物测量装置进行分析物测量的方法。 分析物测量提供有多个穿透构件和分析物传感器。 每个分析物传感器位于样品室中，体积不大于1ul。 每个样品室具有工作电极，参比电极和对电极。 工作电极具有导体，酶和介体。 穿透构件和未使用的分析物检测构件被呈现在活动位置。 然后执行以下步骤：（a）将穿透构件烧制以刺穿皮肤并将流体样品带到分析物检测构件，（b）测量分析物水平，和（c）不超过10秒 从通过测量分析物水平的步骤将穿透构件和未使用的分析物呈现到活动位置的步骤。

    Apparatus for sampling body fluid
    22.
    发明授权
    Apparatus for sampling body fluid 失效
    用于体液取样的装置

    公开(公告)号：US06015392A

    公开(公告)日：2000-01-18

    申请号：US160500

    申请日：1998-09-24

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  Ryszard Radwanski ,  Brent G. Duchon

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  Ryszard Radwanski ,  Brent G. Duchon

    IPC分类号： A61B5/00 ,  A61B5/15

    CPC分类号： A61B5/15016 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150396 ,  A61B5/150503 ,  A61B5/15113 ,  A61B5/15117 ,  A61B2562/0295

    摘要： Body fluid is sampled by causing a syringe mounted in a housing to be displaced toward a skin surface. The syringe remains in the resulting incision while the surrounding body tissue is stimulated by a stimulator ring to urge body fluid toward the incision. Simultaneously, the syringe is moved relative to the incision to keep the incision open. Such movement of the syringe may comprise reciprocation in the longitudinal or lateral directions, or both. Alternatively, the movement of the syringe may comprise rotation about a longitudinal center line of the syringe, with the pointed end of the syringe being in the shape of one-half of a cone segment. After the body fluid has been pooled, suction is created in a collection tube disposed in communication with the syringe, to draw body fluid inwardly through the syringe.

    摘要翻译： 通过使安装在壳体中的注射器朝向皮肤表面移位来取样体液。 注射器保持在所产生的切口中，而周围的身体组织被刺激环刺激以将体液推向切口。 同时，注射器相对于切口移动以保持切口打开。 注射器的这种移动可以包括在纵向或横向上的往复运动，或者两者。 或者，注射器的移动可以包括围绕注射器的纵向中心线的旋转，注射器的尖端为圆锥段的一半的形状。 在体液汇集后，在与注射器连通的收集管中产生抽吸，以通过注射器向内吸引体液。

    SAMPLING DEVICES AND METHODS INVOLVING RELATIVELY LITTLE PAIN
    29.
    发明申请
    SAMPLING DEVICES AND METHODS INVOLVING RELATIVELY LITTLE PAIN 审中-公开
    采用相关的轻度疼痛的装置和方法

    公开(公告)号：US20160038068A1

    公开(公告)日：2016-02-11

    申请号：US14689553

    申请日：2015-04-17

    申请人： Seventh Sense Biosystems, Inc.

    发明人： Donald E. Chickering, III ,  Howard Bernstein ,  Shawn Davis ,  Ramin Haghgooie ,  Douglas A. Levinson ,  Mark Michelman ,  Ping Gong

    IPC分类号： A61B5/15 ,  A61B5/151

    CPC分类号： A61B5/150984 ,  A61B5/1411 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/150022 ,  A61B5/150091 ,  A61B5/150099 ,  A61B5/150106 ,  A61B5/150129 ,  A61B5/150145 ,  A61B5/15016 ,  A61B5/150229 ,  A61B5/150389 ,  A61B5/150412 ,  A61B5/150442 ,  A61B5/150969 ,  A61B5/15105 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15119 ,  A61B5/15125 ,  A61B5/15134 ,  A61B5/15136 ,  A61B5/1514 ,  A61B5/15186 ,  A61B5/1519 ,  A61B5/15194 ,  A61B5/154 ,  A61B5/157 ,  A61B17/00234 ,  A61B2010/0225 ,  A61B2562/0238 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0046

    摘要： The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood, from subjects, e.g., to the skin and/or from the skin. In one aspect, the present invention is generally directed to devices and methods for receiving blood from a subject, e.g., from the skin, using devices including a substance transfer component (which may contain, for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In certain embodiments, substances may be received from and/or delivered to the subject with relatively little pain. The pain may be assessed, for example, using pain scales such as the Wong-Baker FACES Pain Scale. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

    摘要翻译： 本发明一般涉及用于递送和/或接受诸如血液的物质或物质从受试者例如皮肤和/或从皮肤接收的系统和方法。 一方面，本发明一般涉及使用包括物质转移组分（其可以包含例如一个或多个微针）的装置从例如皮肤接收血液的装置和方法，以及 存储室在接收血液之前具有小于大气压的内部压力。 在某些实施方案中，可以相对较少的疼痛从受试者接受和/或递送物质。 可以评估疼痛，​​例如使用诸如Wong-Baker FACES Pain Scale的疼痛量表。 在一些情况下，该装置可以是独立的，并且在某些情况下，可以将该装置应用于皮肤并被激活以从受试者接收血液。 然后可以处理装置或其一部分，以单独或与外部装置一起确定血液和/或血液内的分析物。 例如，可以从装置接收血液，和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。 本发明的其它方面涉及用于接收血液（或其他体液，例如间质液）的其他装置，涉及这种装置的试剂盒，制造这种装置的方法，使用这种装置的方法等。