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    MEANS FOR SECURING A CATHETER INTO A VESSEL
    21.
    发明申请
    MEANS FOR SECURING A CATHETER INTO A VESSEL 审中-公开
    将管道安装到船只中的手段

    公开(公告)号：US20120078078A1

    公开(公告)日：2012-03-29

    申请号：US13186192

    申请日：2011-07-19

    Applicant: David P. MacAdam ,  Charles A. Gibson ,  Dustin Dufour

    Inventor： David P. MacAdam ,  Charles A. Gibson ,  Dustin Dufour

    IPC: A61B5/05

    CPC classification number: A61B5/042 ,  A61B5/0422 ,  A61B5/6853 ,  A61B5/6858 ,  A61M25/04

    Abstract: An electrophysiology catheter, e.g., a coronary sinus catheter, for insertion into a cardiac vessel, such as the coronary sinus, includes a handle and a catheter shaft coupled at one end to the handle. The catheter shaft has a distal end and an anchor is associated with the catheter shaft and is movable between a deployed position and a collapsed position. In the deployed position, the anchor extends radially outward from an outer surface of the catheter shaft for contacting a wall and temporarily anchoring the catheter shaft within the coronary sinus. The catheter also includes an actuator for causing deployment and collapsing of the anchor upon manipulation of the actuator.

    Abstract translation: 用于插入心脏容器（例如冠状窦）的电生理学导管，例如冠状静脉窦导管，包括手柄和一端连接到手柄的导管轴。 导管轴具有远端，并且锚固体与导管轴相关联并且可在展开位置和折叠位置之间移动。 在展开位置，锚固体从导管轴的外表面径向向外延伸，用于接触壁并临时将导管轴锚定在冠状窦内。 导管还包括用于在操纵致动器时使锚固件展开和塌缩的致动器。

    Articulated Catheter
    22.
    发明申请
    Articulated Catheter 有权
    铰接导管

    公开(公告)号：US20080139999A1

    公开(公告)日：2008-06-12

    申请号：US10536109

    申请日：2005-05-17

    Applicant: Charles A. Gibson ,  Gary S. O'Boyle ,  Gary S. Falwell

    Inventor： Charles A. Gibson ,  Gary S. O'Boyle ,  Gary S. Falwell

    IPC: A61M25/092 ,  A61M25/00

    CPC classification number: A61M25/0147 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0108 ,  A61M25/0141 ,  A61M25/0144 ,  A61M2025/0161

    Abstract: Methods and apparatuses for manipulating an elongated flexible shaft of a catheter provide case and reliability of positioning electrodes against or near tissue. Dual-bend flexible distal tips (30) may be used in combination with flat wires. In some embodiments, flat wires which are free to rotate upon initial bending of shaft segments are employed. In some embodiments, one or more transition segments (48) are used to relocate the satellite lumen-to-main lumen transition of pull wires (42, 40) away from a change in shaft stiffness.

    Abstract translation: 用于操纵导管的细长柔性轴的方法和装置提供了定位电极抵靠或靠近组织的壳体和可靠性。 双弯曲柔性远端头（30）可以与扁平线组合使用。 在一些实施例中，采用在轴段的初始弯曲时自由旋转的扁平线。 在一些实施例中，一个或多个过渡段（48）用于将拉线（42,44）的卫星管腔到主腔的过渡位置远离轴刚度的变化。

    Handle design for a medical catheter
    23.
    发明授权
    Handle design for a medical catheter 有权
    处理医用导管的设计

    公开(公告)号：US07331958B2

    公开(公告)日：2008-02-19

    申请号：US10475941

    申请日：2002-04-26

    Applicant: Gary S. Falwell ,  Charles A. Gibson ,  Steven J. Burns

    Inventor： Gary S. Falwell ,  Charles A. Gibson ,  Steven J. Burns

    IPC: A61B18/18 ,  A61M31/00

    CPC classification number: A61B18/1492 ,  A61B18/1815 ,  A61B2018/00214 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/1435

    Abstract: A handle for use with a catheter, the handle including a housing, a cable, and a guide. The housing has a proximal end, a distal end, and a longitudinal axis that extends from the proximal end of the housing to the distal end of the housing. The cable is disposed in the housing and extends through the proximal end of the housing. A portion of the cable that is disposed in the housing is movable, under compression, in a first direction that is substantially aligned with the longitudinal axis of the housing. The guide is disposed in the housing and is adapted to prevent the portion of the cable from moving in a second direction that is transverse to the first direction when the portion of the cable is moved in the first direction. The handle is suitable for use with an electrophysiology catheter having an elongated shaft.

    Abstract translation: 与导管一起使用的手柄，手柄包括壳体，电缆和引导件。 壳体具有近端，远端和从壳体的近端延伸到壳体的远端的纵向轴线。 电缆设置在壳体中并且延伸穿过壳体的近端。 设置在壳体中的电缆的一部分在压缩下可在基本上与壳体的纵向轴线对准的第一方向上移动。 引导件设置在壳体中并且适于当电缆的该部分沿着第一方向移动时防止电缆的该部分在与第一方向横切的第二方向上移动。 手柄适用于具有细长轴的电生理导管。

    Electrophysiology catheter for mapping and/or ablation
    25.
    发明授权
    Electrophysiology catheter for mapping and/or ablation 有权
    用于映射和/或消融的电生理学导管

    公开(公告)号：US07300438B2

    公开(公告)日：2007-11-27

    申请号：US10475942

    申请日：2002-03-29

    Applicant: Gary S. Falwell ,  Steven J. Burns ,  Charles A. Gibson ,  David MacAdam ,  Nickolas G. Davis

    Inventor： Gary S. Falwell ,  Steven J. Burns ,  Charles A. Gibson ,  David MacAdam ,  Nickolas G. Davis

    IPC: A61B18/18 ,  A61M31/00

    CPC classification number: A61B18/1492 ,  A61B18/1815 ,  A61B2018/00839 ,  A61B2018/1435

    Abstract: Catheters for mapping and/or ablation are disclosed. In one embodiment, the catheter comprises a handle, a flexible shaft, a tip assembly, and a cable. The handle includes an actuator and is attached, at its distal end, to the proximal end of the flexible shaft. The flexible shaft has a longitudinal axis that extends along a length of the shaft. The proximal end of the tip assembly is attached to the distal end of the shaft and includes a fixed bend of approximatley ninety degrees relative to the longitudinal axis of the shaft. The distal end of the tip assembly includes an arcuate curve having a diameter. The arcuate curve is oriented in a plane that is approximatley perpendicular to the longitudinal axis of the shaft. The cable is attached to the actuator and the distal end of the tip assembly, and extends through the shaft. The cable is adapted to change the diameter of the arcuate curve in response to movement of the actuator.

    Abstract translation: 公开了用于映射和/或消融的导管。 在一个实施例中，导管包括手柄，柔性轴，尖端组件和电缆。 手柄包括致动器，并且在其远端处附接到柔性轴的近端。 柔性轴具有沿着轴的长度延伸的纵向轴线。 尖端组件的近端附接到轴的远端，并且包括相对于轴的纵向轴线近似90度的固定弯曲部。 尖端组件的远端包括具有直径的弓形曲线。 弧形曲线在垂直于轴的纵向轴线的平面中定向。 电缆连接到致动器和尖端组件的远端，并延伸穿过轴。 电缆适于响应于致动器的移动而改变弧形曲线的直径。

    Steerable catheter
    28.
    发明授权
    Steerable catheter 失效
    导向导管

    公开(公告)号：US06783510B1

    公开(公告)日：2004-08-31

    申请号：US09349451

    申请日：1999-07-08

    Applicant: Charles A. Gibson ,  Hab Seang

    Inventor： Charles A. Gibson ,  Hab Seang

    IPC: A61M3700

    CPC classification number: A61M25/0147 ,  A61M2025/0161

    Abstract: A catheter includes a pull wire which extends through two different lumen and attaches to the distal end of the catheter at an off-axis location. By tensioning the pull wire, the catheter can assume various complex curves, depending on the respective lumen through which the pull wire passes.

    Abstract translation: 导管包括拉线，其延伸穿过两个不同的内腔并且在离轴位置处附接到导管的远端。 通过拉紧拉线，根据拉丝通过的相应内腔，导管可以呈现各种复杂曲线。

    Aminoethylethanolamine producers composition and method for producing same
    29.
    发明授权
    Aminoethylethanolamine producers composition and method for producing same 失效
    氨基乙基乙醇胺生产者的组成及其制备方法

    公开(公告)号：US5068329A

    公开(公告)日：1991-11-26

    申请号：US576988

    申请日：1990-09-04

    Applicant: Lloyd M. Burgess ,  Charles A. Gibson

    Inventor： Lloyd M. Burgess ,  Charles A. Gibson

    IPC: C07C209/16 ,  C07C213/02 ,  C07D295/023

    CPC classification number: C07D295/023 ,  C07C209/16 ,  C07C213/02

    Abstract: A continuously generated alkyleneamines produces composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present,a) about 50 to about 90 mole % AEEA,b) less than about 3 mole % EDA but more than 0.01 mole % EDA,c) less than about 2 mole % DETA but more than 0.01 mole % DETA,d) about 5 to about 18 mole % of the combination of PIP, AEP and HEP,e) about 5 to about 20 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polyamines,g) a mole ratio of AEEA to the combination of PIP, AEP, HEP, DETA and EDA is greater than about 2.5,h) an AEEA to EDA mole ratio greater than about 22 andi) an AEEA to PIP mole ratio greater than about 7;and a process of manufacturing the same, which comprises feeding hydrogen and MEA to a reaction zone containing a fixed bed of a reductive amination catalyst, wherein the hydrogen comprises about 20 to about 80 mole percent of the feed in the reaction zone, the temperature of the reaction zone is about 120.degree. C. to about 300.degree. C., the pressure of the reaction zone is about 200 to about 1200 psig., the conversion of MEA is about 15 to about 42 weight percent, and recovering said producers composition from the reaction zone.

    Abstract translation: 连续生成的亚烷基胺产生组合物，其基于组合物的摩尔数的100％，不包括存在的任何MEA和水，a）约50至约90摩尔％的AEEA，b）小于约3摩尔％的EDA但大于 0.01摩尔％EDA，c）小于约2摩尔％DETA但大于0.01摩尔％DETA，d）PIP，AEP和HEP的组合约5至约18摩尔％，e）约5至约20摩尔％ 的一种或多种TETA和TEPAs，f）小于约1摩尔％的其它聚亚烷基多胺，g）AEEA与PIP，AEP，HEP，DETA和EDA的组合的摩尔比大于约2.5，h） AEEA至EDA摩尔比大于约22，i）AEEA至PIP摩尔比大于约7; 以及其制造方法，其包括将氢气和MEA进料到含有还原胺化催化剂的固定床的反应区，其中氢包含反应区中进料的约20至约80摩尔％，温度 反应区为约120℃至约300℃，反应区的压力为约200至约1200psig，MEA的转化率为约15至约42重量％，并将所述生产者组合物从 反应区。

    Continuous process for preparing alkanolamines
    30.
    发明授权
    Continuous process for preparing alkanolamines 失效
    链烷醇胺的连续工艺

    公开(公告)号：US4847418A

    公开(公告)日：1989-07-11

    申请号：US196802

    申请日：1988-05-16

    Applicant: Charles A. Gibson ,  Moinuddin Ahmed ,  James R. Nelson

    Inventor： Charles A. Gibson ,  Moinuddin Ahmed ,  James R. Nelson

    IPC: C07C213/04

    CPC classification number: C07C213/04

    Abstract: A continuous process is provided for preparing alkanolamines having a high yield of monoalkanolamine, which comprises continuously reacting a flowing stream of a homogeneous mixture of an alkylene oxide having from two to four carbon atoms and ammonia in a molar ratio of ammonia to alkylene oxide within the range from about 15:1 to about 50:1 at temperatures above the critical temperature of the mixture and at pressures above the critical pressure of the mixture and maintaining the mixture in a single phase having a density of at least 15 lbs./cu.ft. for the time necessary to form an alkanolamine product mixture containing at least about 65% by weight monoalkanolamine.

    Abstract translation: 提供了一种制备具有高产率的单链烷醇胺的链烷醇胺的连续方法，其包括将具有2至4个碳原子的烯化氧的均匀混合物的流动流与氨与氧化烯的摩尔比连续反应 在高于混合物的临界温度的温度下在约15:1至约50:1的范围内，并且在高于混合物的临界压力的压力下，将混合物保持在密度为至少15lbs./cu的单相中。 英尺 在形成含有至少约65重量％的单链烷醇胺的链烷醇胺产物混合物所需的时间。

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