公开(公告)号：US11793774B2

公开(公告)日：2023-10-24

申请号：US16646492

申请日：2018-09-13

申请人： ATROGI AB

发明人： Benjamin Pelcman ,  Tore Bengtsson

IPC分类号： A61K31/137 ,  C07C213/04 ,  C07C215/30 ,  C07C215/34 ,  A61K45/06 ,  A61P3/10

CPC分类号： A61K31/137 ,  A61K45/06 ,  A61P3/10 ,  C07C213/04 ,  C07C215/30 ,  C07C215/34

摘要： There is herein provided a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4 and n have meanings as provided in the description.

公开(公告)号：US11224667B2

公开(公告)日：2022-01-18

申请号：US16315305

申请日：2017-06-30

申请人： NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY

发明人： Masaaki Suzuki ,  Kengo Ito ,  Takashi Kato ,  Hiroshi Ikenuma ,  Hiroko Koyama

IPC分类号： C07C213/04 ,  A61K51/04 ,  C07B59/00

摘要： An object of the invention is to provide an 11C-labeled catechol derivative having sufficient radioactivity to obtain an imaging image by a PET apparatus, a PET probe of a phosphorylated tau aggregation inhibitor using the same, and a method for producing them. The 11C-labeled catechol derivative of the present invention is represented by the following general formula (a) (wherein R is a substituent having an isopropylamino group, and the carbon at the 2-position of the isopropylamino group is labeled with 11C).

公开(公告)号：US20210379574A1

公开(公告)日：2021-12-09

申请号：US17340658

申请日：2021-06-07

申请人： The Curators of the University of Missouri

发明人： Ali A. Rownaghi ,  Fateme Rezaei ,  Abdo-Alslam Alwakwak

IPC分类号： B01J31/12 ,  B01J37/04 ,  B01J37/06 ,  B01J37/08 ,  B01J35/10 ,  B01J8/02 ,  C07D263/22 ,  C07C213/04 ,  D01D5/24 ,  D01F11/00

摘要： Described herein are multi-functionalized hollow fiber organocatalysts, processes for producing multi-functionalized hollow fiber organocatalysts, and processes that utilize multi-functionalized hollow fiber organocatalysts for reacting chemicals. A variety of chemical reactions may be enhanced with the multifunctional hollow fiber organocatalysts. The multi-functionalized hollow fiber organocatalysts are particularly advantageous when used as heterogeneous organocatalysts and continuous-flow reactors.

公开(公告)号：US11186791B2

公开(公告)日：2021-11-30

申请号：US16496162

申请日：2018-03-28

申请人： Innospec Limited

发明人： Alan Norman Ross ,  Martin Roberts

IPC分类号： C10L1/222 ,  C10L1/19 ,  C10L10/18 ,  C10L1/223 ,  C07C211/63 ,  C07C215/40 ,  C07C217/08 ,  C10L10/08 ,  C07C209/24 ,  C07C213/04 ,  C07C69/40 ,  C07C67/317 ,  C10M133/06

摘要： A quaternary ammonium compound of formula (I): (I) wherein R0, R1, R2 and R3 is each independently an optionally substituted hydrocarbyl group, X is a linking group, R4 is an optionally substituted alkylene group, R5 is hydrogen or an optionally substituted alkyl, alkenyl or aryl group, and n is 0 or a positive integer, provided that n is not 0 when R5 is hydrogen.

公开(公告)号：US10934249B2

公开(公告)日：2021-03-02

申请号：US16353607

申请日：2019-03-14

申请人： Saudi Arabian Oil Company

发明人： Matthew Hilfiger ,  B. Raghava Reddy

IPC分类号： C07C213/00 ,  C09K8/36 ,  C07B41/02 ,  C07C215/10 ,  C07C215/14 ,  C07C213/04

摘要： N-hydroxyalkylated polyamines, methods of making N-hydroxyalkylated polyamines, and drilling fluids containing N-hydroxyalkylated polyamines are provided, in which the N-hydroxyalkylated polyamine includes Formula (I): where R1 and R2 are independently a —C or —CH group; R3 is an aliphatic hydrocarbyl; R4 and R5 are independently acyclic hydrocarbyls, or R1, R2, R4, and R5 are covalently connected to form a cyclic hydrocarbyl; and R6, R7, R8, and R9 are independently acyclic hydrocarbyls or acyclic heterohydrocarbyls.

公开(公告)号：US10774034B2

公开(公告)日：2020-09-15

申请号：US16610131

申请日：2018-05-03

申请人： BASF SE

发明人： Alvaro Gordillo ,  Andrei-Nicolae Parvulescu ,  Armin Lange De Oliveira ,  Andreas Kuschel ,  Juergen Bechtel ,  Johannes Lieberknecht ,  Ulrich Müller ,  Johann-Peter Melder ,  Christian Gruenanger

IPC分类号： C07C213/04 ,  B01J29/24 ,  B01J29/40 ,  B01J29/70 ,  C07C215/08 ,  B01J37/30 ,  C01B39/26 ,  C01B39/38 ,  C07C211/10 ,  B01J37/08

摘要： The present invention relates to a process for the conversion of ethylene oxide to 2-aminoethanol and/or ethane-1,2-diamine and/or linear polyethylenimines of the formula H2N—(CH2CH2NH)n—CH2CH2—NH2 wherein n≥1 comprising (i) providing a catalyst comprising a zeolitic material comprising YO2 and X2O3, wherein Y is a tetravalent element and X is a trivalent element; (ii) providing a gas stream comprising ethylene oxide and ammonia; (iii) contacting the catalyst provided in (i) with the gas stream provided in (ii) for converting ethylene oxide to 2-aminoethanol and/or ethane-1,2-diamine and/or linear polyethylenimines.

公开(公告)号：US20200157445A1

公开(公告)日：2020-05-21

申请号：US16496162

申请日：2018-03-28

申请人： INNOSPEC LIMITED

发明人： Alan Norman ROSS ,  Martin ROBERTS

IPC分类号： C10L1/222 ,  C10L1/19 ,  C10L10/18 ,  C10L1/223 ,  C07C211/63 ,  C07C215/40 ,  C07C217/08 ,  C10L10/08 ,  C07C209/24 ,  C07C213/04 ,  C07C69/40 ,  C07C67/317 ,  C10M133/06

摘要： A quaternary ammonium compound of formula (I): (I) wherein R0, R1, R2 and R3 is each independently an optionally substituted hydrocarbyl group, X is a linking group, R4 is an optionally substituted alkylene group, R5 is hydrogen or an optionally substituted alkyl, alkenyl or aryl group, and n is 0 or a positive integer, provided that n is not 0 when R5 is hydrogen.

公开(公告)号：US20180044308A1

公开(公告)日：2018-02-15

申请号：US15554922

申请日：2016-03-02

申请人： SABIC Global Technologies B.V.

发明人： Talal Al-Shammari ,  Khalid Karim ,  Zeeshan Nawaz ,  Ali Al-Hammad ,  Shehzada Khurram ,  Mubarik Ali Bashir ,  Labeeb Chaudhary Ahmed ,  Abdullah Turki Al-Jaloud ,  Saud Al-Khudeer ,  Thabet Al-Qahtani

IPC分类号： C07D301/03 ,  C07C1/04 ,  C07C5/32 ,  C07C9/06 ,  C10G2/00 ,  C07C29/10 ,  C07C31/20 ,  C07C213/04 ,  C07C215/08 ,  C07D301/32 ,  C07C11/04

CPC分类号： C07D301/03 ,  C07C1/0485 ,  C07C5/32 ,  C07C5/321 ,  C07C9/06 ,  C07C11/04 ,  C07C29/106 ,  C07C31/202 ,  C07C213/04 ,  C07C215/08 ,  C07D301/32 ,  C10G2/00

摘要： Disclosed herein is a method comprising the steps of: a) producing a hydrocarbon stream from syngas via a Fischer-Tropsch reaction, wherein the hydrocarbon stream comprises a first C2 hydrocarbon stream comprising ethane and a first ethylene product; b) separating at least a portion of the first C2 hydrocarbon stream from the hydrocarbon stream; c) separating at least a portion of the first ethylene product from the first C2 hydrocarbon stream, thereby producing a second C2 hydrocarbon stream; d) converting at least a portion of the ethane in the second C2 hydrocarbon stream to a second ethylene product; and e) producing ethylene oxide from at least a portion of the second ethylene product.

公开(公告)号：US20170022145A1

公开(公告)日：2017-01-26

申请号：US15302600

申请日：2015-04-06

申请人： SABIC GLOBAL TECHNOLOGIES B.V.

发明人： Naeem Al-Hazmi

IPC分类号： C07C213/04 ,  B01D3/14 ,  B01D3/32 ,  C07C213/10

CPC分类号： C07C213/04 ,  B01D3/143 ,  B01D3/322 ,  C07C213/10 ,  Y02P20/127 ,  C07C215/08 ,  C07C215/10

摘要： Systems and method are provided for reducing the water content in ethanolamine product streams from approximately 0.15%-0.19% by weight of water to approximately 0.02 to approximately 0.04 by weight of water. The reduced water content can be achieved by increasing the processing conditions at the monoethanolamine column by approximately 5% to approximately 20%, more preferably to approximately 10%, and by adding a dummy stream to the monoethanolamine column, which can be recycled to the reactor. The increased processing conditions and dummy stream at the monoethanolamine column can result in the following to achieve said water content: (i) the bottom stream flow rate increase by up to approximately 18.9%; the reboiler duty can be increased by up to 47.9%; and (iii) the condenser duty can be increased by up to approximately 52.5%.

摘要翻译： 提供的系统和方法用于将乙醇胺产物流中的水含量从约0.15％-0.19％（重量）的水减少至约0.02至约0.04重量％的水。 降低的水含量可以通过将单乙醇胺柱的加工条件增加约5％至约20％，更优选至约10％，并通过向单乙醇胺塔中加入虚拟物流来实现，其可循环至反应器 。 在单乙醇胺塔处加工条件和虚拟物流的增加可能导致以下因素达到所述含水量：（i）底部流量增加高达约18.9％; 再沸器的使用税可以增加47.9％。 和（iii）冷凝器功能可以增加高达约52.5％。

公开(公告)号：US09233909B2

公开(公告)日：2016-01-12

申请号：US13981008

申请日：2012-01-16

申请人： Hisayuki Kuwahara ,  Tomotaka Wada

发明人： Hisayuki Kuwahara ,  Tomotaka Wada

IPC分类号： C07C211/00 ,  C07C209/60 ,  C07C213/00 ,  C07C213/04 ,  C07C213/02

CPC分类号： C07C209/60 ,  C07C213/00 ,  C07C213/02 ,  C07C213/04 ,  C07C2601/14 ,  C07C2602/42 ,  C07C211/27 ,  C07C217/08

摘要： The present invention relates to a process for producing an amino compound by subjecting a polyamine and an alkenyl compound to addition reaction in the presence of an alkali metal hydride compound which is capable of supplying the amino compound in a stable manner without occurrence of odor.

摘要翻译： 本发明涉及通过在碱性金属氢化物化合物的存在下使多胺和链烯基化合物进行加成反应来制备氨基化合物的方法，所述碱金属氢化物化合物能稳定地供给氨基化合物而不产生气味。