公开(公告)号：US09937104B2

公开(公告)日：2018-04-10

申请号：US15399869

申请日：2017-01-06

申请人： UNIVERSITY OF MARYLAND, BALTIMORE

发明人： Huakun Xu ,  Michael Weir

IPC分类号： A61K6/00 ,  A61K6/02 ,  A61K6/06 ,  A61K6/083

CPC分类号： A61K6/0067 ,  A61K6/0023 ,  A61K6/02 ,  A61K6/0235 ,  A61K6/024 ,  A61K6/0643 ,  A61K6/083 ,  C08L33/10 ,  A61K6/0029 ,  A61K6/0017

摘要： The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.

公开(公告)号：US09932416B2

公开(公告)日：2018-04-03

申请号：US15121504

申请日：2015-02-26

申请人： Universita' Degli Studi Di Trieste

发明人： Sergio Paoletti ,  Roberto Di Lenarda ,  Lorenzo Breschi ,  Milena Cadenaro ,  Marina Diolosa' ,  Gianluca Turco ,  Ivan Donati

IPC分类号： A61L24/08 ,  A61K6/097 ,  C08B37/08 ,  A61K6/083

CPC分类号： C08B37/003 ,  A61K6/083 ,  A61K6/097 ,  A61L24/08 ,  C08L33/08 ,  C08L5/08

摘要： The present invention concerns the preparation of chemically modified derivatives of chitosan with acrylic groups and their use in the field of enamel-dentin adhesives. Chitosan derivatives have physical-chemical features (hydrophilicity, presence of electrical charges on the chain) which allow them to interact with the organic part of the demineralized tooth. At the same time, the acrylic groups incorporated in the polymer chain allow the formation of a covalent bond with the restorative material used in the dental field that is typically composed of acrylic resins. By combining the adhesion to the tooth surface and the bond with the restorative material, the chemically modified chitosan described herein is able to increase the lifespan of the dental restoration and can thus find use in the field of adhesives, in particular enamel-dentin adhesives.

公开(公告)号：US09931280B2

公开(公告)日：2018-04-03

申请号：US14505687

申请日：2014-10-03

申请人： DENTSPLY INTERNATIONAL INC.

发明人： Hui Lu ,  Xiaoming Jin ,  Joachim E. Klee ,  Bernard Koltisko

IPC分类号： A61K6/08 ,  A61K6/083 ,  C07D295/24 ,  A61K6/00

CPC分类号： A61K6/083 ,  A61K6/0008 ,  C07D295/24 ,  C08L33/10

摘要： A dental composite composition is disclosed that includes a polymerizable resin, filler particles, and at least one polymerizable stable radical. A variety of polymerizable stable radicals may be employed, including those that have a 2,2,6,6-tetramethylpiperidinyl-1-oxyl moiety. Compositions as described herein exhibit excellent mechanical strength, hardness, and flexural modulus, while also significantly decreasing shrinkage stress caused by polymerization.

公开(公告)号：US09925126B2

公开(公告)日：2018-03-27

申请号：US15486579

申请日：2017-04-13

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Brant U. Kolb ,  Bryan C. Feisel ,  Martin Goetzinger ,  Philip S. Hall ,  Holger Hauptmann ,  Mark J. Hendrickson ,  Kathleen M. Humpal ,  John W. Longabach ,  James P. Mathers ,  Roberta R. Naujok ,  Paul D. Pennington ,  Gallus Schechner

IPC分类号： A61K6/02 ,  C04B35/64 ,  C04B35/488 ,  C01G25/02 ,  A61K6/00 ,  A61C13/08 ,  C08J9/28 ,  A61C7/28 ,  A61C13/00 ,  A61C8/00 ,  C04B35/624 ,  A61K6/083 ,  C01G25/00 ,  C04B35/486 ,  B82Y30/00 ,  C08J9/00 ,  A61C5/77 ,  A61C5/20

CPC分类号： A61K6/024 ,  A61C5/20 ,  A61C5/77 ,  A61C7/282 ,  A61C8/0001 ,  A61C8/0012 ,  A61C8/0048 ,  A61C13/0006 ,  A61C13/0022 ,  A61C13/082 ,  A61K6/0002 ,  A61K6/0008 ,  A61K6/025 ,  A61K6/0255 ,  A61K6/083 ,  B82Y30/00 ,  C01G25/00 ,  C01G25/006 ,  C01G25/02 ,  C01P2002/50 ,  C01P2002/52 ,  C01P2002/60 ,  C01P2002/84 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/10 ,  C04B35/486 ,  C04B35/488 ,  C04B35/624 ,  C04B35/64 ,  C04B38/00 ,  C04B38/0045 ,  C04B2111/00836 ,  C04B2235/3217 ,  C04B2235/3225 ,  C04B2235/3227 ,  C04B2235/3244 ,  C04B2235/549 ,  C04B2235/6562 ,  C04B2235/6565 ,  C04B2235/6567 ,  C04B2235/661 ,  C04B2235/77 ,  C04B2235/781 ,  C04B2235/785 ,  C04B2235/80 ,  C04B2235/96 ,  C04B2235/9646 ,  C04B2235/9661 ,  C08J9/008 ,  C08J9/28 ,  C08J2201/038 ,  C08J2201/04 ,  C08J2201/0502 ,  C08J2203/08 ,  C08J2205/026 ,  C08J2205/042 ,  C08J2207/10 ,  C08J2333/02 ,  C08J2333/10 ,  C08J2333/14 ,  Y02P20/544 ,  C04B38/0054 ,  C04B38/0058 ,  C04B38/0074

摘要： Aerogel, calcined articles, and crystalline articles comprising ZrO2. Exemplary uses of the crystalline metal oxide articles include dental articles (e.g., restoratives, replacements, inlays, onlays, veneers, full and partial crowns, bridges, implants, implant abutments, copings, anterior fillings, posterior fillings, and cavity liner, and bridge frameworks) and orthodontic appliances (e.g., brackets, buccal tubes, cleats, and buttons).

公开(公告)号：US09920062B2

公开(公告)日：2018-03-20

申请号：US14782936

申请日：2014-04-08

申请人： Xiaoming Xu ,  Stephen Costin

发明人： Xiaoming Xu ,  Stephen Costin

IPC分类号： A61K6/083 ,  C07C229/14 ,  C08L33/02 ,  C07D487/08 ,  A61K6/00

CPC分类号： C07D487/08 ,  A61K6/0047 ,  C07C229/14 ,  A61K6/083 ,  C08L33/10

摘要： Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking properties and are hydrolytically stable. The compounds may be utilized in dental and/or medical applications, including dental composites, dentures, bonding agents, sealants, resins and medical devices.

公开(公告)号：US09901520B2

公开(公告)日：2018-02-27

申请号：US14955240

申请日：2015-12-01

申请人： Muhlbauer Technology GmbH

发明人： Stephan Neffgen ,  Swen Neander

IPC分类号： A61K6/083 ,  C08F22/10

CPC分类号： A61K6/083 ,  C08F22/10 ,  C08L33/04

摘要： The invention provides an infiltrant for dental application that comprises crosslinking monomers. In accordance with the invention the infiltrant has a penetration coefficient PC>50 cm/s, and the crosslinking monomers, based on the total mass of monomers, comprise at least 5% by weight of crosslinking monomers having at least three polymerizable groups and not more than 95% by weight of crosslinking monomers having two polymerizable groups.

公开(公告)号：US20180036209A1

公开(公告)日：2018-02-08

申请号：US15661359

申请日：2017-07-27

申请人： Ivoclar Vivadent AG

发明人： Norbert Moszner ,  Yohann CateI ,  Urs Karl Fischer ,  Sven Tauscher

IPC分类号： A61K6/083 ,  C07C69/743 ,  C08F22/10 ,  A61K6/00

CPC分类号： A61K6/083 ,  A61K6/0023 ,  A61K6/0052 ,  C07C69/743 ,  C07C233/58 ,  C07C2601/02 ,  C08F22/105 ,  C08F220/10 ,  C08F222/14 ,  C08F222/36 ,  C08L33/08 ,  C08L33/10

摘要： Dental material which contains at least one vinylcyclopropane of the general formulae I, in which A, B independently of each other are in each case OH or COOH; X, Y independently of each other are in each case O or NH; R1, R2 independently of each other are in each case H or an aliphatic linear or branched C1-C10 hydrocarbon radical which can be interrupted by O, S or an ester group; and n, m independently of each other are in each case 0, 1 or 2, wherein, if X=Y=O, R1≠H and R2≠H, n+m≧1. The vinylcyclopropanes are characterized by a low shrinkage and a high reactivity on radical polymerization and are suitable in particular for the preparation of dental materials.

公开(公告)号：US20180028413A1

公开(公告)日：2018-02-01

申请号：US15552751

申请日：2016-03-01

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Bradley D. Craig ,  Gregory A. Kobussen

IPC分类号： A61K6/02 ,  A61K6/083 ,  C04B35/80 ,  A61K6/00

CPC分类号： A61K6/0205 ,  A61K6/0005 ,  A61K6/0008 ,  A61K6/0017 ,  A61K6/0073 ,  A61K6/083 ,  C04B35/806 ,  C08L33/00

摘要： The present disclosure provides a composite material, a method of making and using the composite material and dental products made by hardening the composite material. The composite material includes a polymerizable component, ceramic fibers and nanoclusters. Each of the ceramic fibers of the composite material has a length and where the length of fifty percent of the ceramic fibers, based on a total number of the ceramic fibers, is at least 50 micrometers and the length of ninety percent of the ceramic fibers, based on the total number of the ceramic fibers, is no greater than 500 micrometers. The composite material can also include discrete non-fumed metal oxide nanoparticles. The composite material can be hardened to become any one of a dental restorative, a dental adhesive, a dental mill blank, a dental cement, a dental prostheses, an orthodontic device, an orthodontic adhesive, a dental casting material or a dental coating.

公开(公告)号：US09861557B2

公开(公告)日：2018-01-09

申请号：US14904129

申请日：2014-07-11

申请人： Ivoclar Vivadent AG

发明人： Norbert Moszner ,  Yohann Catel

IPC分类号： A61K6/083 ,  A61K6/00

CPC分类号： A61K6/083 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0052 ,  C08L33/14

摘要： Dental material which contains a urea derivative according to general formula I, in which R1 and R2 are in each case independently of each other an aliphatic C1-C15 radical which can be interrupted by —O—, —S—, —CO—O—; X is a radically polymerizable group; Y is a radically polymerizable group or an acid group; n, m are in each case independently of each other 1, 2, or 3.

公开(公告)号：US09861458B2

公开(公告)日：2018-01-09

申请号：US14695353

申请日：2015-04-24

申请人： Bruce Willard Hultgren ,  Steven Mark Rzepecki

发明人： Bruce Willard Hultgren ,  Steven Mark Rzepecki

IPC分类号： A61C13/20 ,  A61C13/00 ,  A61B5/11 ,  A61C9/00 ,  A61K6/10 ,  A61C13/34 ,  G05B19/4099 ,  A61C8/00 ,  A61B5/00 ,  A61C19/05

CPC分类号： A61C5/77 ,  A61B5/0037 ,  A61B5/0088 ,  A61B5/1111 ,  A61B5/1128 ,  A61C9/0006 ,  A61C9/0053 ,  A61C13/0004 ,  A61C13/34 ,  A61C19/052 ,  A61C2008/0084 ,  A61K6/10 ,  G05B19/4099 ,  G05B2219/35044 ,  G05B2219/37555 ,  G05B2219/45167 ,  G05B2219/49008 ,  A61K6/083 ,  C08L33/08

摘要： A system for fabricating a dental restoration to restore a tooth at a restoration site in a dentition of a patient is disclosed. The dentition includes a restoration dental arch and an opposing dental arch. The restoration dental arch include the restoration site and the opposing dental arch is opposite the restoration dental arch. The system includes an impression apparatus, a motion capture apparatus, an interface apparatus, and a restoration design system. The impression apparatus is configured to capture an impression of the dentition of the patient. The motion capture apparatus is configured to capture a plurality of location data points that represent the locations of the opposing dental arch relative to the restoration dental arch. The interference model generation system is configured to generate an interference model for the restoration site. The restoration design system is for designing a restoration using the interference model.